Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8BG0M)

Drug Name

FP-253-GDEPT Drug Info

Synonyms

FP-253; PNP-GDEPT; GDEPT (prostate cancer), Mayne; GDEPT (fludarabine phosphate, prostate cancer), CSIRO; Gene-directed enzyme prodrug therapy (prostate cancer), Mayne; OAdV gene therapy (PNP/ fludarabine phosphate), Mayne; Ovine adenovirus gene therapy (purine nucleoside phosphorylase/fludarabine phosphate), Mayne; OAdV GDEPT (E coli PNP/fludarabine phosphate, prostate cancer), Broadvector; Ovine atadenovirus GDEPT (purine nucleoside phosphorylase/fludarabine phosphate, prostate cancer), Biotech Equity Partners

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1	[1]

Cross-matching ID

TTD Drug ID: DM8BG0M

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Schistosoma Purine nucleoside phosphorylase (sch PNP)	TTVYIH7	Q9BMI9_SCHMA	Modulator	[1]

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References

1	Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer. J Gene Med. 2004 Dec;6(12):1343-57.