Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8GRJK)

Drug Name

Rapamycin Drug Info

Synonyms

MTOR inhibitors

Indication

Disease Entry	ICD 11	Status	REF
Lymphangioleiomyomatosis	CB07	Approved	[1]
Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[2]
Severe acute respiratory syndrome (SARS)	1D65	Investigative	[2]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting HUMAN mammalian target of rapamycin (mTOR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sirolimus	DMGW1ID	Advanced cancer	2A00-2F9Z	Approved	[3]
Everolimus	DM8X2EH	Advanced cancer	2A00-2F9Z	Approved	[2]
Sapanisertib	DMYZFNH	Breast cancer	2C60-2C65	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN mammalian target of rapamycin (mTOR)	TT7HQAF	MTOR_HUMAN	Inhibitor	[2]

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
3	Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2. Cell Discov. 2020 Mar 16;6:14.
4	Prevent COVID-19 Severity by Repurposing mTOR Inhibitors. 2 April 2020