Details of the Drug

General Information of Drug (ID: DM8GRJK)

Drug Name
Rapamycin
Synonyms MTOR inhibitors
Indication
Disease Entry ICD 11 Status REF
Lymphangioleiomyomatosis CB07 Approved [1]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [2]
Severe acute respiratory syndrome (SARS) 1D65 Investigative [2]
Therapeutic Class
Antiviral Agents
Affected Organisms
Humans and other mammals
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 914.2
Logarithm of the Partition Coefficient (xlogp) 6
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 13
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 2: low solubility and high permeability [3]
Elimination
2% of drug is excreted from urine in the unchanged form [3]
MRTD
The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 0.14767 micromolar/kg/day [4]
Chemical Identifiers
Formula
C51H79NO13
IUPAC Name
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Canonical SMILES
C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
InChI
InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1
InChIKey
QFJCIRLUMZQUOT-HPLJOQBZSA-N
Cross-matching ID
PubChem CID
5284616
ChEBI ID
CHEBI:9168
CAS Number
53123-88-9
UNII
W36ZG6FT64
DrugBank ID
DB00877
TTD ID
D05VYY
ACDINA ID
D00627
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HUMAN mammalian target of rapamycin (mTOR) TT7HQAF MTOR_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 0.0615 6.5026 -7.878 3.787
ES4 GDSC1; GDSC2 -6.364 -1.3436 -7.333 28.7942
NOS-1 [Human HNSCC] GDSC1; GDSC2 -6.0986 1.4824 -8.3029 31.2483
SK-PN-DW GDSC1; GDSC2 -4.9823 2.64 -7.7789 25.8381
ES6 GDSC1; GDSC2 -4.6742 10.6584 -11.4687 34.3716
EW-16 GDSC1; GDSC2 -2.4693 10.0148 -9.2937 24.3474
EW-12 GDSC1; GDSC2 -1.902 15.8348 -11.7442 31.6482
A-673 GDSC2; CTRP2 -1.6518 25.3465 -11.1129 43.0621
HuO9 GDSC2 -1.3262 20.5253 -15.3277 28.5509
EW-1 GDSC1; GDSC2 -1.2656 10.2857 -8.4972 19.3949
CADO-ES1 GDSC2 -0.8884 8.7652 -9.3768 11.3442
CHSA8926 GDSC2 -0.6544 17.2433 -13.2432 23.3047
ES8 GDSC1; GDSC2 -0.5633 11.6071 -8.6309 18.5186
HuO-3N1 GDSC2 -0.4973 8.3134 -8.9436 8.9234
CHSA0011 GDSC2 -0.483 19.2656 -12.3458 29.9477
EW-7 GDSC2 -0.3126 7.3233 -8.4086 6.3857
TC-71 GDSC1; GDSC2 -0.0482 1.8089 -3.9165 0.1415
EW-11 GDSC1; GDSC2 0.0128 17.1496 -10.9289 23.8332
H-EMC-SS GDSC1; GDSC2 0.0759 10.4949 -7.6449 13.9621
ES1 GDSC1; GDSC2 0.1161 22.1378 -13.3125 28.3122
CAL-72 GDSC2 0.1672 20.4201 -14.2083 24.1232
ES5 GDSC1; GDSC2 0.2315 2.8674 -4.1841 0.6068
ES7 GDSC1; GDSC2 0.3046 3.1325 -4.2519 0.6077
NY GDSC2 0.3326 4.1302 -6.8688 0.5361
U-CH2 GDSC2 0.367 11.2645 -7.8172 16.2792
EW-3 GDSC1; GDSC2 0.4252 11.7926 -8.0305 14.7831
EW-22 GDSC1; GDSC2 0.5761 11.2307 -7.6624 13.2209
Hs 888.T CTRP2 0.675 44.7371 -18.5513 46.1434
EW-24 GDSC1; GDSC2 0.8404 8.9961 -6.455 8.163
CHSA0108 GDSC2 1.0037 13.0665 -8.2522 16.7166
EW-13 GDSC1 1.0208 13.6109 -8.5 19.6669
EW-18 GDSC1; GDSC2 1.2667 18.7563 -10.8101 21.5429
SK-ES-1 GDSC1; GDSC2; CTRP2 1.6077 21.1375 -6.0194 33.1548
MHH-ES-1 GDSC2; CTRP2 2.2609 15.1191 -2.4663 25.866
G-292 clone A141B1 GDSC2; CTRP2 4.2946 31.5813 -8.854 32.4907
TC71 CTRP2 4.2988 6.8136 3.4813 8.1667
Hs 822.T CTRP2 5.4503 6.8841 4.4369 1.8681
U2OS GDSC2; CTRP2; CTRP1 7.5269 25.1326 -2.8928 19.4263
SK-N-MC CTRP2 7.5791 48.5985 -14.658 37.0325
SaOS-2 GDSC2; CTRP2 7.6264 21.0797 -0.9364 14.293
CAL-78 GDSC2; CTRP2 8.4665 25.0825 -2.2855 16.5378
SJSA-1 GDSC1; GDSC2; CTRP2 8.8867 45.2381 -11.947 30.3415
MG-63 GDSC2; CTRP2 10.5503 39.1899 -7.6853 23.8544
HOS GDSC2; CTRP2 12.0062 24.988 0.1033 7.4108
SW1353 CTRP2 13.9309 36.4651 -4.0211 17.6359
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 220 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -0.5859 64.5719 -29.5324 48.4283
MEC1 CTRP2 -0.3002 75.8443 -34.9025 48.448
JM1 GDSC1; GDSC2; CTRP2 7.8771 32.1107 -6.2065 26.2325
KMS-34 CTRP2 -15.8475 -2.6187 -16.211 88.4128
OCI-Ly3 CTRP2 -14.4567 10.6918 -18.0095 73.3968
BL-70 CTRP2; CTRP1 -12.4972 17.4773 -18.4422 67.3481
SUP-B8 GDSC2 -12.0175 -7.8703 -12.0548 79.6383
SU-DHL-6 GDSC1; GDSC2; CTRP2 -11.9827 10.0557 -15.1127 64.9364
BCP-1 CTRP2 -11.9084 8.8291 -14.6131 72.2079
Daudi GDSC1; GDSC2; CTRP2 -11.4559 11.4036 -15.0268 63.4159
Ri-1 CTRP2 -11.4494 17.138 -17.2597 66.2173
Ramos.2G6.4C10 GDSC1; GDSC2 -11.1141 6.7623 -15.7481 54.8241
MOLP-8 GDSC1; GDSC2; CTRP2 -10.7857 0.3106 -11.2071 69.7281
OCI-Ly10 CTRP2; CTRP1 -10.7686 29.9451 -22.1114 60.9852
KHM-1B CTRP2 -10.5186 29.1382 -21.567 60.8314
SU-DHL-16 GDSC1; GDSC2 -9.5826 2.7282 -12.4028 55.3356
KMS-20 CTRP2 -9.3058 34.1927 -22.7166 58.4609
CRO-AP2 GDSC2 -9.1934 166.2095 -93.0289 50.2783
KMS-26 CTRP2 -9.1841 12.7069 -13.0867 65.6024
Pfeiffer CTRP2 -9.0246 23.1521 -17.3467 60.7976
DoHH2 GDSC1; GDSC2; CTRP2 -8.8068 32.8336 -21.5887 56.0343
OPM-2 GDSC1; GDSC2; CTRP2 -7.7734 3.3821 -8.5277 59.1952
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 -7.6835 44.0158 -25.763 53.8161
Karpas-231 GDSC1; GDSC2 -7.561 1.7832 -9.912 40.5144
BE-13 GDSC1; GDSC2 -7.5307 4.4345 -11.0926 42.0161
Farage GDSC1; GDSC2 -7.3702 80.3896 -48.5973 49.416
Jiyoye GDSC1; GDSC2 -7.3445 5.5832 -11.4506 41.7948
Ki-JK CTRP2 -7.0844 14.6633 -11.6574 60.9763
JVM-2 GDSC1; GDSC2; CTRP2 -7.0461 4.2912 -8.3299 52.9545
SU-DHL-8 GDSC1; GDSC2; CTRP2 -6.7051 26.4846 -16.5491 52.2657
SR GDSC1; GDSC2; CTRP2 -6.6666 18.9283 -13.0639 52.788
GR-ST GDSC1; GDSC2 -6.6187 88.2412 -51.879 48.3549
QIMR-WIL GDSC1; GDSC2 -6.6178 5.8615 -10.884 43.0602
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -6.5935 8.2968 -8.6729 54.0699
A4/Fukuda GDSC1; GDSC2; CTRP2 -6.2169 23.235 -14.559 51.6613
SU-DHL-5 GDSC2; CTRP1 -6.0682 -1.6261 -6.0835 54.1222
WIL2 NS GDSC1; GDSC2 -5.9726 9.2828 -11.9499 38.3866
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -5.761 16.2728 -10.9022 51.2856
NU-DHL-1 CTRP2 -5.7418 54.905 -29.3609 52.9503
CESS GDSC1; GDSC2 -5.638 2.8637 -8.5072 30.3354
Karpas-422 GDSC1; GDSC2; CTRP2 -5.5991 23.5401 -14.0858 50.5689
OCI-Ly7 GDSC2 -5.5603 6.21 -10.0613 38.2513
KOPN-8 GDSC1; GDSC2 -5.44 5 -9.3574 32.0755
Mino CTRP2 -5.3299 63.6908 -33.3175 52.2712
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 -5.1261 10.3143 -7.783 53.3879
RC-K8 GDSC2 -4.9311 8.6025 -12.1821 29.3159
VL51 GDSC1; GDSC2 -4.9119 6.2074 -9.4688 30.8284
KE-37 GDSC1; GDSC2; CTRP2 -4.9003 11.0341 -7.8772 48.8684
EoL-1 GDSC1; GDSC2; CTRP2 -4.8757 18.9718 -11.2663 49.1285
MHH-PREB-1 GDSC1; GDSC2 -4.7727 2.947 -7.7347 25.0498
CCRF-CEM GDSC1; GDSC2 -4.76 4.9579 -8.7139 28.3049
Karpas-1106P GDSC2 -4.5204 7.712 -11.4102 26.225
PL-21 GDSC1; GDSC2 -4.4125 3.7608 -7.8087 28.4599
ARH-77 GDSC1; GDSC2 -4.3907 9.146 -10.4675 31.7696
EB1 CTRP2 -4.132 33.1527 -17.236 52.4211
JSC-1 GDSC1; GDSC2 -4.0979 6.286 -8.787 26.7202
KE-97 CTRP2; CTRP1 -4.0941 10.398 -6.7155 55.8464
SUP-T11 CTRP2 -4.0925 16.0239 -9.149 54.2127
L-363 GDSC1; GDSC2; CTRP2 -3.9355 12.6021 -7.5039 46.1242
H9 GDSC1; GDSC2 -3.8836 12.2334 -11.5725 32.716
697 GDSC1; GDSC2; CTRP2 -3.7914 26.4003 -13.6644 47.4106
GA-10 GDSC1; GDSC2; CTRP2 -3.3755 16.9356 -8.8313 45.3323
MM1.S GDSC2; CTRP2 -3.2884 18.7534 -9.5758 45.4395
JVM-3 GDSC1; GDSC2; CTRP2 -3.2788 9.4882 -5.5467 43.1395
LC4-1 GDSC1; GDSC2 -3.2609 9.1353 -9.4998 26.7021
MOLT-4 GDSC1; GDSC2 -3.1022 4.9239 -7.2632 18.7726
CA46 GDSC1; GDSC2; CTRP2 -3.0954 18.0399 -9.0548 44.8228
KMS-11 GDSC2; CTRP2; CTRP1 -3.071 38.7386 -18.8729 48.7533
SUP-M2 GDSC1; GDSC2; CTRP2 -3.0604 1.7568 -3.1665 39.4675
BONNA-12 GDSC2 -3.0516 20.7446 -15.1307 38.3009
Karpas-299 GDSC1; GDSC2; CTRP2 -3.021 13.0633 -6.7511 43.3793
M-07e CTRP2 -2.6064 96.6848 -47.298 50.0804
ATN-1 GDSC1; GDSC2 -2.4982 12.1304 -10.3728 27.2309
P32/ISH GDSC1; GDSC2 -2.4565 14.3282 -11.4366 29.4476
BALL-1 GDSC1; GDSC2 -2.3787 7.9611 -8.198 20.6651
L-540 GDSC1; GDSC2; CTRP2 -2.217 17.6981 -8.0233 42.4082
MY-M12 GDSC1; GDSC2 -2.1786 11.3904 -9.7483 27.9929
DB GDSC1; GDSC2; CTRP2 -2.1182 11.9526 -5.3389 39.8878
KM-H2 GDSC1; GDSC2; CTRP2 -2.0755 12.7662 -6.5379 36.7983
Hs 611.T CTRP2 -2.0155 58.2617 -27.6547 49.5968
MOLT-16 GDSC1; GDSC2; CTRP2 -1.9666 7.3123 -3.3273 36.7117
L-428 GDSC1; GDSC2; CTRP2 -1.8604 16.6316 -7.1754 41.0307
MLMA GDSC1; GDSC2 -1.732 23.7457 -15.5547 34.2478
Jurkat GDSC2; CTRP2 -1.7097 11.0794 -5.3915 34.1805
NCI-H929 GDSC2; CTRP2 -1.6872 24.0215 -10.507 42.8279
NK-92MI GDSC1; GDSC2 -1.5556 9.6126 -8.3826 22.4226
BC-3 GDSC1; GDSC2 -1.4843 10.4075 -8.7218 23.3922
MN-60 GDSC1; GDSC2 -1.3736 9.0607 -7.974 17.7868
HC-1 GDSC1; GDSC2 -1.3187 15.5812 -11.1603 26.6932
CML-T1 GDSC2; CTRP2 -1.1971 17.7599 -7.0477 39.5385
BV-173 GDSC1; GDSC2; CTRP2 -1.1514 21.652 -8.8561 40.8913
MEG-01 GDSC1; GDSC2 -0.9913 6.5028 -6.4539 10.9671
NCO2 CTRP2 -0.9624 37.9329 -16.6397 47.9164
HT GDSC1; GDSC2; CTRP2; CTRP1 -0.936 29.0493 -12.1526 44.5449
Raji GDSC1; GDSC2; CTRP2 -0.8717 30.0103 -12.6568 42.5433
KMS-12-BM GDSC1; GDSC2; CTRP2 -0.7847 12.5737 -4.2447 35.3122
Karpas-45 GDSC1; GDSC2 -0.7218 10.6946 -8.2991 17.6975
Mono-Mac-1 CTRP2 -0.7134 29.025 -12.0276 46.8569
MOLT-3 CTRP2 -0.6377 72.6374 -33.5967 48.6394
KMS-28BM CTRP2 -0.4654 43.4069 -18.9021 47.5328
CTV-1 GDSC1; GDSC2 -0.341 17.8154 -11.5208 25.731
TK [Human B-cell lymphoma] GDSC2 -0.3314 1.5449 -6.2366 0.017
MHH-CALL-2 GDSC2 -0.2699 3.8106 -6.9818 0.9996
SUP-HD1 GDSC1; GDSC2; CTRP2 -0.2341 28.2387 -11.2 40.8446
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 -0.2207 23.4222 -8.7411 39.4077
MV4-11 GDSC1; CTRP2 -0.1848 13.0127 -3.8388 39.4479
ALL-PO GDSC1; GDSC2 -0.1569 7.9792 -6.6027 10.2214
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -0.1516 57.4259 -25.4907 45.2603
PF-382 GDSC1; GDSC2; CTRP2 -0.1048 25.0666 -9.5261 39.5551
VAL GDSC1; GDSC2 -0.0965 24.5303 -14.6598 30.648
ML-2 GDSC1; GDSC2 -0.0877 12.0784 -8.5216 17.318
KMOE-2 GDSC1; GDSC2 -0.0826 3.989 -4.761 2.4171
BC-1 GDSC1; GDSC2 -0.0173 9.2639 -7.1197 12.1002
HAL-01 GDSC1; GDSC2 0.0765 16.3979 -10.5129 22.7357
YT GDSC1; GDSC2 0.0837 2.4043 -4.0748 0.3352
CTB-1 GDSC1; GDSC2 0.1358 19.5425 -12.016 28.2385
DG-75 GDSC1; GDSC2 0.2142 9.0427 -6.8642 10.7148
ROS-50 GDSC1; GDSC2 0.2565 18.5541 -11.4399 26.8819
Loucy GDSC1; GDSC2 0.2877 14.0143 -9.1971 18.804
WSU-NHL GDSC1; GDSC2 0.2947 14.8596 -9.6033 19.9721
KMS-21-BM CTRP2 0.4135 20.2417 -6.6902 42.5203
RPMI-8866 GDSC1; GDSC2 0.4313 16.1877 -10.1532 21.2347
DND-41 GDSC1; GDSC2; CTRP2 0.5118 19.2951 -6.1385 35.2546
U-698-M GDSC1; GDSC2 0.5411 18.0187 -10.9692 23.0574
P30/OHK GDSC1; GDSC2 0.6044 10.6758 -7.3816 12.1325
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 0.6851 21.1361 -6.7799 38.4575
SCC-3 GDSC1; GDSC2 0.6874 14.3238 -9.0682 17.7566
ME1 GDSC1; GDSC2 0.7082 9.764 -6.8889 10.0755
RCH-ACV GDSC2; CTRP2 0.7206 57.1679 -24.7028 45.3509
KY821 GDSC1; GDSC2 0.7228 2.7586 -3.97 0.0952
PL21 CTRP2; CTRP1 0.7343 20.8747 -6.6065 42.0294
IM-9 GDSC1; GDSC2 0.8206 15.8133 -9.6958 19.3697
ST486 GDSC1; GDSC2; CTRP2 0.8309 14.8938 -3.7178 31.0415
HuT 78 CTRP2 0.8587 9.2408 -1.0922 33.7594
EM-2 GDSC1; GDSC2; CTRP2 0.8655 28.7411 -10.4444 38.7007
TUR GDSC1; GDSC2 0.8877 12.3905 -8.0077 13.9714
NKM-1 GDSC1; GDSC2 0.8924 13.0914 -8.3379 15.0944
MC116 GDSC1; GDSC2; CTRP2; CTRP1 1.0047 31.8125 -11.7405 41.4032
BL-41 GDSC1; GDSC2; CTRP2 1.013 24.0245 -7.9841 36.4059
L-1236 GDSC1; GDSC2; CTRP2 1.025 35.4774 -13.6391 40.4082
SEM CTRP2 1.025 26.5704 -9.2279 42.8032
MOTN-1 CTRP2 1.0743 57.5288 -24.5755 46.5899
EB2 GDSC1; GDSC2 1.177 13.3871 -8.2903 14.4964
Granta-519 GDSC1; GDSC2; CTRP2 1.258 17.5479 -4.5879 31.6938
JJN-3 GDSC1; GDSC2; CTRP2 1.2854 37.8016 -14.5634 40.5382
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 1.3085 11.2698 -1.4705 25.904
P3HR-1 CTRP2; CTRP1 1.3792 32.9861 -11.9872 43.6509
MOLM-13 GDSC1; GDSC2; CTRP2 1.4356 23.0184 -7.1027 34.7758
HuNS1 CTRP2 1.4371 48.0762 -19.547 45.4689
OCI-Ly19 GDSC1; GDSC2; CTRP2 1.4765 21.0128 -6.0785 35.882
NALM-6 GDSC1; GDSC2; CTRP2 1.5084 20.0015 -5.5526 32.6888
KG-1 GDSC1; GDSC2 1.6606 14.8227 -8.6537 14.9624
Namalwa GDSC1; GDSC2; CTRP2 1.7605 35.1592 -12.8302 39.0178
Hs 445 GDSC1; GDSC2 1.8142 15.0854 -8.678 14.8157
U-937 CTRP2; CTRP1 2.3604 7.0828 1.4445 22.0655
P31/FUJ GDSC1; GDSC2; CTRP2 2.4129 10.5577 -0.1256 19.7807
SUP-T1 GDSC1; GDSC2; CTRP2 2.4453 25.856 -7.5996 33.7334
MOLT-13 GDSC2; CTRP2 2.4731 22.1127 -5.7171 31.2932
RPMI-6666 GDSC1; GDSC2; CTRP2 2.5452 26.111 -7.6378 33.6249
MOLM-16 GDSC2; CTRP2; CTRP1 2.5744 46.9457 -17.8933 42.0209
JeKo-1 GDSC2; CTRP2 2.6114 39.0498 -14.0261 40.2255
EHEB GDSC1; CTRP2 2.6163 36.1051 -12.5531 40.8813
F-36P CTRP2 2.6531 46.3375 -17.6273 43.6786
Reh GDSC1; GDSC2; CTRP2 3.0001 12.5807 -0.5386 19.8638
U266B1 GDSC1; GDSC2; CTRP2 3.0648 14.4925 -1.4162 22.0154
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 3.1209 15.9131 -1.9691 26.1417
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 3.1324 5.5956 2.8266 12.1124
SU-DHL-1 GDSC1; GDSC2; CTRP2 3.4789 7.3304 2.4304 11.8207
DEL GDSC1; GDSC2; CTRP2 3.6204 3.9898 3.6203 6.8951
KCL-22 GDSC1; GDSC2; CTRP2 3.6514 25.5698 -6.4011 30.4272
AML-193 CTRP2 3.894 10.9421 1.0894 18.7044
Mono-Mac-6 GDSC1; GDSC2; CTRP2 4.4171 26.1286 -6.0249 28.7831
OCI-M1 GDSC1; GDSC2; CTRP2 4.6073 5.0252 4.5725 2.2044
LAMA-84 GDSC1; GDSC2; CTRP2 4.6186 26.9229 -7.6036 26.7186
ALL-SIL GDSC1; GDSC2; CTRP2 4.7597 14.9785 -0.1618 16.0278
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 4.8191 37.3181 -11.1713 34.2626
KMS-18 CTRP2 5.1823 41.2861 -12.9617 38.7614
REC-1 CTRP2 5.1992 7.0589 4.163 3.4166
Kasumi-2 CTRP2 5.3145 56.7176 -20.5675 41.835
KMM-1 CTRP2 5.3732 12.3081 1.6828 13.3457
Karpas-620 GDSC1; GDSC2; CTRP2 5.436 6.7995 4.4679 1.2815
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 5.5726 16.4242 -0.0982 15.2641
RS4;11 GDSC1; GDSC2; CTRP2 5.5849 27.8976 -5.9349 27.0401
RPMI-8402 GDSC1; GDSC2; CTRP2 5.6714 26.7708 -5.3008 25.9229
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 5.7839 27.2508 -5.4487 27.8871
OCI-AML-2 GDSC1; GDSC2; CTRP2 6.1835 19.5182 -1.2665 16.9402
MHH-CALL-3 CTRP2 6.1851 26.0098 -4.5035 28.7046
JURL-MK1 GDSC1; GDSC2; CTRP2 6.191 43.5033 -13.2381 34.1586
RL GDSC1; GDSC2; CTRP2 6.2241 44.0727 -13.4956 35.7282
Toledo CTRP2 6.3654 28.2536 -5.4786 29.9745
A3/Kawakami GDSC1; GDSC2; CTRP2 6.4232 31.9014 -7.2531 27.8519
NB4 GDSC1; GDSC2; CTRP2 6.5455 7.4092 4.7676 0.0466
TF-1 CTRP2 6.6139 7.7077 4.6888 0.1388
SK-MM-2 GDSC1; GDSC2; CTRP2 6.8261 9.1312 4.2254 0.8535
EJM GDSC1; GDSC2; CTRP2; CTRP1 6.8748 27.4313 -4.5459 23.4374
HEL 92.1.7 CTRP2 6.9272 7.8608 4.7474 0.0335
Peer CTRP2 7.0001 43.5028 -12.5802 36.3494
K-562 GDSC1; GDSC2; CTRP2 7.026 9.8131 4.0387 1.1691
KMS-27 CTRP2 7.0844 40.6631 -11.0948 35.1445
HDLM-2 GDSC1; GDSC2; CTRP2 7.1084 33.3004 -7.4025 27.2236
SU-DHL-10 GDSC2; CTRP2 7.5359 26.2397 -3.5552 20.3446
Kasumi-1 GDSC1; GDSC2; CTRP2 7.9899 25.2958 -2.7436 19.7036
HPB-ALL CTRP2 8.0179 20.4834 -0.3592 16.0213
Ci-1 CTRP2 8.4627 24.6268 -2.0647 20.0483
ME1 CTRP2 8.5472 19.8431 0.3216 13.0999
MHH-CALL-4 GDSC2; CTRP2 8.6018 43.0879 -11.1001 31.2291
SUP-B15 GDSC1; GDSC2; CTRP2 8.9363 32.0318 -5.359 22.0196
MOLM-6 CTRP2 9.051 36.0932 -7.2805 28.7173
SIG-M5 GDSC1; GDSC2; CTRP2 9.1685 50.4482 -14.3188 33.31
P12-Ichikawa GDSC2; CTRP2 9.3936 22.6396 -0.4457 11.1047
KYO-1 CTRP2 9.4538 32.9115 -5.4069 25.4277
SET-2 CTRP2 10.1259 24.4274 -0.8096 14.4177
MOLP-2 CTRP2 10.1636 42.2077 -9.4626 29.9842
HD-MY-Z CTRP2 11.4807 38.2231 -6.5349 24.7187
HL-60 GDSC1; GDSC2; CTRP2 11.945 26.7703 -0.7481 9.4902
KO52 CTRP2 12.1558 33.0685 -3.576 18.6687
HEL GDSC1; GDSC2; CTRP2 12.5757 30.8716 -3.0653 12.6657
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 12.5888 32.4844 -2.8773 14.0498
OCI-AML-5 GDSC1; GDSC2; CTRP2 15.182 35.0681 -2.5965 10.9373
CMK CTRP2 15.2208 31.9729 -1.183 10.0354
⏷ Show the Full List of 220 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 7.3904 36.4457 -8.7465 32.5987
TE8 CTRP2 9.7113 27.1691 -2.4112 19.1244
TE-15 GDSC1; GDSC2 -6.3597 1.0534 -8.3668 32.3726
OE21 GDSC2; CTRP2 -2.3768 19.3872 -8.9688 43.303
TE-5 GDSC1; GDSC2; CTRP2 -0.7205 22.8689 -9.0332 40.2446
TE-6 GDSC1; GDSC2; CTRP2 0.1798 56.7611 -24.9719 44.786
KYSE-270 GDSC2 0.2226 4.9012 -7.1864 1.3049
T.T GDSC2 0.3606 2.9767 -6.473 0.0769
TE-8 GDSC1 0.5465 51.5285 -27.5937 41.6226
KYSE-410 GDSC2; CTRP2; CTRP1 1.1433 22.3699 -6.9572 35.4056
KYSE-140 GDSC2; CTRP2; CTRP1 2.7133 8.531 1.1879 16.1616
KYSE-150 GDSC2; CTRP2 4.123 4.9663 4.059 4.6226
OE33 GDSC2; CTRP2 5.4547 31.4942 -7.8401 29.8246
TE-10 GDSC1; GDSC2; CTRP2 6.6392 38.1506 -11.6039 31.0171
OE19 GDSC2; CTRP2 6.9622 8.1894 4.6483 0.0859
TE-9 GDSC1; GDSC2; CTRP2 7.1256 8.4776 4.6075 0.0995
EC-GI-10 GDSC1; GDSC2; CTRP2 7.5809 25.5115 -3.1598 19.4825
KYSE-70 GDSC2; CTRP2 8.5134 29.4801 -4.4166 20.8378
TE-14 CTRP2 9.0174 23.4309 -1.0852 16.677
KYSE-180 GDSC2; CTRP2 9.3442 20.2787 -1.0538 6.458
TE-4 GDSC2; CTRP2 9.8371 24.6188 -1.0942 12.2663
KYSE-510 GDSC2; CTRP2 10.1487 25.647 -1.3763 13.8513
KYSE-30 CTRP2 10.6424 27.6513 -2.0028 16.9206
KYSE-520 GDSC2; CTRP2 10.7468 46.5651 -11.1763 27.8114
KYSE-450 GDSC2; CTRP2; CTRP1 12.5734 25.1286 0.511 6.4843
TE-1 GDSC1; GDSC2; CTRP2 13.2481 32.5544 -2.6228 12.5401
COLO 680N GDSC2; CTRP2 14.1064 38.1785 -4.7159 15.8335
TE-11 GDSC1; GDSC2; CTRP2 16.72 41.9709 -4.8335 14.9275
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 16.5571 51.3696 -9.3685 23.4945
Hs 766T GDSC2; CTRP2 -0.4528 23.609 -9.1402 39.8578
KP-1N GDSC2 -0.2779 3.3816 -6.8312 0.6519
PL4 GDSC2 -0.0913 4.2951 -7.0885 1.1958
MZ-PC-1 GDSC1; GDSC2 0.1799 9.5819 -7.1408 13.8853
BxPC-3 GDSC2; CTRP2 2.5021 30.83 -10.0239 36.026
KP-3 GDSC2; CTRP2; CTRP1 4.2635 15.8154 -0.9011 19.309
PK-59 CTRP2 4.521 45.7289 -15.7357 40.9162
KP-2 GDSC2; CTRP2 4.6395 13.1338 0.6575 13.8811
SU.86.86 GDSC2; CTRP2 4.7177 15.8982 -0.657 17.4313
Panc 04.03 GDSC2; CTRP2 5.1409 11.9123 1.6905 10.0932
PaTu 8902 GDSC2; CTRP2; CTRP1 5.2881 6.5924 4.5824 1.7938
Panc 03.27 GDSC2; CTRP2; CTRP1 5.5903 17.706 -0.7243 16.8995
KP-4 GDSC2; CTRP2 5.7492 17.607 -0.6597 15.9669
Capan-1 GDSC2; CTRP2 6.052 9.5262 3.5775 3.2494
HuP-T3 GDSC2; CTRP2 6.334 21.9522 -2.3603 19.3393
SW1990 GDSC2; CTRP2 6.4494 22.8725 -2.7275 19.9992
HPAF-II GDSC2; CTRP2 6.5397 20.9752 -1.7118 17.5607
PaTu 8988t GDSC2; CTRP2 6.6498 7.7243 4.6963 0.0872
Panc 08.13 GDSC2; CTRP2 6.8804 31.0356 -6.4546 26.1639
SNU-410 CTRP2 7.4314 19.8633 -0.4821 17.3066
PaTu 8988s CTRP2 7.4942 22.2219 -1.598 20.3494
SUIT-2 GDSC2; CTRP2; CTRP1 7.5376 15.2503 1.9718 6.9833
Panc 10.05 GDSC2; CTRP2; CTRP1 7.729 26.4745 -3.4032 20.224
CFPAC-1 GDSC2; CTRP2; CTRP1 7.9371 22.4089 -1.2364 15.1775
DAN-G GDSC2; CTRP2 8.882 39.5437 -9.1207 27.4042
HuP-T4 GDSC2; CTRP2; CTRP1 9.5494 32.8858 -5.1994 21.4316
QGP-1 GDSC2; CTRP2; CTRP1 9.8057 36.3853 -6.7334 25.0411
PK-45H CTRP2 9.9146 43.5875 -10.3341 31.1628
PSN1 GDSC1; GDSC2; CTRP2 10.023 32.9337 -5.0002 20.221
Capan-2 GDSC2; CTRP2; CTRP1 10.7995 32.622 -4.1637 18.2784
MIA PaCa-2 GDSC2; CTRP2 11.02 29.4351 -2.6021 14.5293
AsPC-1 GDSC2; CTRP2 11.095 36.6465 -6.0419 20.8656
TCC-Pan2 CTRP2 11.7975 39.6214 -6.9904 25.0315
YAPC GDSC2; CTRP2 12.0343 31.2557 -2.7938 13.9714
SNU-213 CTRP2 12.2704 31.1251 -2.5776 16.3498
Panc 05.04 CTRP2 12.8314 48.3859 -10.5291 28.3019
Panc 02.03 GDSC2; CTRP2 13.4226 28.6961 -0.7442 8.3076
HPAC GDSC2; CTRP2; CTRP1 13.9919 30.6338 -1.1438 9.2015
L3.3 CTRP2 16.1093 38.2195 -3.4804 14.4261
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 78 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 11.4853 26.8081 -1.0524 13.4399
SH-4 GDSC1; GDSC2 -4.8502 11.6152 -12.0994 35.7915
Hs 938.T GDSC2 -3.0487 11.8721 -10.6925 32.2477
IST-MEL1 GDSC1; GDSC2 -0.6359 28.2082 -16.9082 34.0515
GAK GDSC1; GDSC2 -0.5976 9.0117 -7.3924 14.1529
WM1552C GDSC2 -0.4904 7.1842 -8.4431 6.7594
451Lu GDSC2 -0.4781 2.8224 -4.4722 2.1116
G-mel GDSC2 -0.4449 16.7488 -11.0721 27.4063
A-388 GDSC1; GDSC2 -0.4263 29.1539 -17.2143 35.9213
COLO 783 GDSC2 -0.3529 5.727 -5.6767 7.9101
WM35 GDSC2 -0.2831 6.3574 -7.9848 4.5638
CP50-MEL-B GDSC2 -0.28 12.3543 -8.7923 21.0127
COLO 679 GDSC2 -0.2276 2.3421 -6.4602 0.1138
CHL-1 GDSC2 -0.1783 10.1028 -9.5634 11.0096
A-431 GDSC2 -0.1452 23.9877 -14.428 32.4993
LB2518-MEL GDSC1; GDSC2 -0.039 1.4984 -3.8101 0.0641
Mel Ho GDSC2; CTRP2 0.0034 20.4851 -8.3189 37.3478
HMV-II GDSC2 0.0719 3.5441 -6.7603 0.4196
CP67-MEL GDSC1 0.0933 64.2813 -34.3213 43.6977
WM278 GDSC2 0.1534 2.9974 -6.5484 0.1465
DJM-1 GDSC1; GDSC2 0.1922 3.8789 -4.5852 1.95
SK-MEL-2 GDSC1; GDSC2 0.2758 10.4331 -7.4817 13.0259
MZ-MEL-2 GDSC1; GDSC2 0.3359 35.0044 -19.5286 36.7441
CP66-MEL GDSC1; GDSC2 0.3519 2.4607 -3.9976 0.2073
M14 GDSC2 0.3816 5.9964 -7.5333 2.2692
VMRC-MELG GDSC2 0.4908 3.4187 -4.2832 0.7434
MZ-MEL-7 GDSC1; GDSC2 0.939 23.6719 -13.4533 29.3688
MMAc-SF GDSC1; GDSC2 1.1446 15.1808 -9.1676 19.4954
LB373-MEL-D GDSC1; GDSC2 2.2315 16.5097 -9.0795 17.389
RPMI-7951 GDSC2; CTRP2 2.4778 20.4713 -4.9001 30.0495
Hs 940.T GDSC2; CTRP2 4.0656 41.4605 -13.9857 38.4631
WM983B CTRP2 4.4579 11.0143 1.5576 15.6713
SK-MEL-28 GDSC2; CTRP2; CTRP1 4.5453 13.2269 0.6346 16.4446
WT2-iPS GDSC2; CTRP2 4.8834 5.4157 4.712 1.2662
COLO 829 GDSC1; GDSC2; CTRP2 4.9982 10.5783 2.2389 8.6318
Malme-3M CTRP2 5.0169 7.5796 3.7538 5.4783
UACC-257 GDSC1; GDSC2; CTRP2 5.1366 12.2973 1.4945 10.6888
A-375 GDSC2; CTRP2; CTRP1 5.169 9.5102 3.0253 6.6756
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 5.9031 27.8153 -5.5208 26.3242
Hs 934.T CTRP2 6.1775 19.5954 -1.3097 21.8055
A2058 GDSC2; CTRP2 6.1932 7.4149 4.6249 0.321
SK-MEL-31 GDSC2; CTRP2 6.2865 15.604 0.7606 12.6661
SK-MEL-5 GDSC2; CTRP2; CTRP1 6.3455 10.1954 3.588 3.9842
IGR-37 GDSC2; CTRP2 6.4618 14.6045 1.3881 9.2857
Hs 688(A).T CTRP2 6.5155 7.9784 4.5473 0.4619
Hs 839.T CTRP2 6.7107 15.6326 1.0667 13.3242
A101D GDSC1; GDSC2; CTRP2 6.7388 8.0578 4.6107 0.1679
WM88 CTRP2 6.9614 49.4046 -15.5591 38.1819
Hs 852.T CTRP2; CTRP1 7.2271 93.4278 -37.2298 43.9281
COLO 741 CTRP2; CTRP1 7.938 26.6998 -3.3551 24.207
CJM [Human melanoma] CTRP2 7.9829 17.4871 1.0689 11.3666
G-361 GDSC2; CTRP2; CTRP1 8.4926 27.2341 -3.2008 18.909
WM266-4 CTRP2 9.7099 33.9606 -5.7337 25.626
Hs 944.T CTRP2; CTRP1 9.7828 33.2441 -5.2031 25.0244
MeWo GDSC2; CTRP2 9.9552 23.1378 -0.3099 10.2075
Hs 936.T CTRP2; CTRP1 10.0591 22.3312 0.2741 11.8906
WM115 GDSC2; CTRP2 10.1528 45.2601 -10.981 28.1734
COLO 792 GDSC2; CTRP2 10.3231 28.6153 -2.6846 15.4031
LOX-IMVI GDSC1; GDSC2; CTRP2 10.48 38.1912 -7.246 23.3083
IGR-39 CTRP2 10.4989 51.7481 -13.9321 33.5903
UACC-62 GDSC2; CTRP2 10.4996 21.4885 0.8012 6.8835
Mel JuSo GDSC2; CTRP2 10.8594 25.0833 -0.6426 10.1878
RVH-421 GDSC2; CTRP2 11.0862 24.754 -0.3458 10.2273
SK-MEL-3 GDSC2; CTRP2 11.3774 38.5652 -6.776 23.0785
IGR-1 GDSC2; CTRP2 12.0878 34.3777 -4.2486 16.7941
Hs 895.T CTRP2 12.0881 46.8524 -10.3194 28.8285
WM1799 CTRP2 12.8103 47.5266 -10.1237 27.8893
Hs 294T CTRP2 13.4374 50.1024 -10.9306 28.1298
COLO 800 GDSC1; GDSC2; CTRP2 13.5156 34.5661 -3.3949 14.9771
WM793 GDSC2; CTRP2 13.7545 40.6851 -6.1437 18.5438
HT-144 GDSC1; GDSC2; CTRP2 13.978 35.8233 -3.6893 14.0481
HMCB CTRP2 14.0555 26.5414 0.5515 6.5049
IPC-298 GDSC2; CTRP2 14.2561 43.5624 -7.1836 20.8752
MDA-MB-435S CTRP2 14.4692 38.2394 -4.5096 18.0315
SK-MEL-30 GDSC2; CTRP2 14.5234 36.6957 -3.7516 14.7709
SK-MEL-24 GDSC2; CTRP2 15.0917 41.2955 -5.5476 16.4382
K029AX CTRP2 15.39 44.8429 -7.0338 21.3831
EquiPSC Line K2 GDSC2 -0.5807 16.613 -11.1072 27.7438
⏷ Show the Full List of 78 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 -4.1917 3.1744 -8.909 15.7171
OACM5.1 C GDSC2 -0.8412 7.072 -8.586 7.8603
SK-GT-4 GDSC2 -0.4424 11.4115 -10.3248 14.3275
ESO-51 GDSC2 -0.3353 4.3696 -7.216 1.7123
OACP4 C GDSC2 -0.3014 12.2448 -10.6246 15.169
HCE-4 GDSC1; GDSC2 -0.1396 6.3186 -5.8191 8.2687
FLO-1 GDSC2 -0.0243 4.5346 -7.15 1.3318
KYAE-1 GDSC2 0.0661 2.1997 -6.3183 0.0272
ESO-26 GDSC2 0.0843 11.4086 -10.0014 12.309
KYSE-50 GDSC2 0.1805 6.2129 -7.7066 3.0313
TE-12 GDSC1; GDSC2 0.3331 17.1198 -10.6798 25.0579
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -0.7469 16.0359 -5.7969 37.3121
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -7.7957 27.8759 -18.2747 58.0039
SJNB-13 GDSC1 -3.3861 14.4722 -12.2725 38.3462
GOTO GDSC1; GDSC2 -0.5381 5.7091 -5.7821 7.2648
SJNB-10 GDSC1; GDSC2 -0.4806 5.834 -5.8043 7.2781
LA-N-6 GDSC1; GDSC2 -0.4263 5.475 -5.6055 7.6693
SK-N-BE(2)-M17 GDSC1; GDSC2 -0.3518 6.9222 -6.2309 8.9469
NB(TU)1 GDSC1; GDSC2 -0.2632 4.3546 -5.0106 3.5754
KP-N-YS GDSC1; GDSC2 -0.2107 2.8649 -4.366 1.4433
SK-N-MC-IXC GDSC2 -0.1877 12.9335 -9.0087 21.516
SJNB-17 GDSC1; GDSC2 -0.1517 9.3867 -7.2679 15.0667
SJNB-12 GDSC2 -0.0878 5.4251 -7.5164 2.558
CHP-134 GDSC2 -0.0619 1.7498 -6.2158 0.0095
TGW GDSC1; GDSC2 -0.0388 5.0941 -5.2114 4.1464
SJNB-6 GDSC1; GDSC2 -0.017 5.1207 -5.2111 5.0299
IMR-5 GDSC1; GDSC2 -0.0065 8.8461 -6.9144 11.2627
KP-N-RT-BM-1 GDSC1; GDSC2 0.0189 7.0193 -6.0447 9.1182
NH-12 GDSC1; GDSC2 0.2537 4.5054 -4.8099 2.3
NB69 GDSC1; GDSC2 0.2813 22.0532 -13.146 27.7802
SJNB-14 GDSC1; GDSC2 0.3759 9.5337 -6.9913 10.9737
GI-ME-N GDSC1; GDSC2 0.6459 9.1766 -6.6555 9.2368
SJNB-5 GDSC1; GDSC2 0.8967 10.923 -7.3106 13.2991
SiMa GDSC1; GDSC2 0.9056 3.3945 -4.1206 0.2181
SJNB-7 GDSC1; GDSC2 1.0405 11.6501 -7.5596 12.1371
SK-N-FI GDSC1; GDSC2 1.1608 12.4653 -7.8655 13.0582
SK-N-DZ GDSC1; GDSC2; CTRP2 2.3584 13.2659 -1.4743 23.3963
SK-N-BE(2) CTRP2 3.0061 21.474 -4.9253 35.1703
NB1 GDSC1; GDSC2; CTRP2 3.1216 32.626 -10.3799 35.4908
SK-N-AS GDSC2; CTRP2 4.8184 24.1428 -4.6938 26.0856
CHP-212 GDSC2; CTRP2 5.1553 40.3756 -12.5289 34.7465
MHH-NB-11 GDSC1; GDSC2; CTRP2 5.8719 12.6849 1.8899 9.5828
Kelly GDSC1; GDSC2; CTRP2 6.1443 30.6335 -6.8455 27.6418
CHP-126 GDSC1; GDSC2; CTRP2 6.5703 21.3528 -1.8757 19.6433
NH-6 CTRP2 7.1289 13.4226 2.4393 7.4713
KP-N-SI9s CTRP2 8.6052 59.3898 -19.2209 38.3508
KP-N-YN GDSC1; CTRP2 10.2514 27.8701 -2.3745 17.3747
SK-N-SH GDSC2; CTRP2 13.3253 37.4059 -4.8643 16.7767
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 0.6899 37.4801 -14.9314 46.107
SNU-869 CTRP2 4.9473 6.1893 4.3891 2.9476
SNU-478 CTRP2 6.4484 27.106 -4.8393 28.839
HuH-28 CTRP2 7.0135 8.2055 4.6612 0.0946
SNU-1196 CTRP2 7.1379 8.605 4.5672 0.2029
HuCC-T1 GDSC2; CTRP2 7.6853 9.0572 4.6071 0.0437
SNU-308 CTRP2 11.7004 31.625 -3.1917 18.3837
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1; GDSC2 -11.2369 -9.2019 -11.2373 64.3523
MDA-MB-330 GDSC2 -5.299 14.1099 -13.7357 41.7857
HCC1954 GDSC2; CTRP2 -2.5062 17.3888 -8.1676 43.1103
MRK-nu-1 GDSC1; GDSC2 -1.8072 35.5503 -21.5106 39.0392
DU4475 GDSC1; GDSC2; CTRP2 -1.7058 16.1597 -6.8037 40.383
Evsa-T GDSC1; GDSC2 -1.5711 11.1226 -9.142 22.036
YMB-1-E GDSC2 -1.3305 15.8145 -11.2854 29.6036
EFM-192A GDSC2; CTRP2 -0.7173 25.0695 -10.0986 40.9527
HCC1187 GDSC1; GDSC2 -0.491 11.2966 -8.4273 17.714
MDA-MB-415 GDSC2 -0.4241 51.727 -30.1037 39.4534
ZR-75-1 CTRP2 -0.3283 61.3551 -27.7048 48.1132
UACC-893 GDSC2 -0.2253 21.2002 -13.1076 30.7495
SK-BR-3 CTRP2 -0.1969 33.4678 -13.7411 46.3845
HCC70 GDSC2 0.0223 15.2047 -11.8086 18.4367
MDA-MB-175-VII GDSC2 0.122 3.0254 -6.5682 0.1677
UACC-812 GDSC1; GDSC2 0.1255 12.6951 -8.6711 17.4419
HCC1599 GDSC1; GDSC2 0.129 26.3953 -15.4117 33.274
CAL-148 GDSC1; GDSC2; CTRP2 0.1699 17.3186 -5.5121 35.1078
HCC2157 GDSC1; GDSC2 0.2133 13.1123 -8.8118 17.7433
BT-483 GDSC2 0.2253 8.0845 -8.454 5.9322
COLO 824 GDSC1; GDSC2 0.2427 10.4604 -7.5167 13.2106
EFM-19 GDSC2 0.2455 3.5545 -6.7027 0.2993
MDA-MB-436 GDSC2 0.3844 7.8428 -8.2726 5.0237
MCF-7 GDSC2; CTRP2; CTRP1 0.4401 23.9825 -8.3976 38.0071
MFM-223 GDSC1; GDSC2 0.6256 2.3006 -3.8525 0.0349
MDA-MB-453 GDSC2; CTRP2 0.8236 35.6483 -13.9032 40.7982
MDA-MB-361 GDSC2; CTRP2 0.8698 31.1537 -11.6339 39.4872
Hs 578T GDSC2; CTRP2 1.2036 31.993 -11.7509 39.0957
CAL-51 GDSC2; CTRP2 1.8889 30.5334 -10.4167 37.2011
AU565 GDSC2; CTRP2 2.7463 33.5275 -11.1549 36.6081
HCC1143 GDSC2; CTRP2 3.0565 22.388 -5.3351 29.7894
MDA-MB-157 GDSC2; CTRP2 3.8123 5.9756 2.9053 4.212
HCC1419 GDSC2; CTRP2 4.0259 21.5991 -4.0963 26.1961
CAL-120 GDSC2; CTRP2 4.4855 14.4289 -0.1214 16.3259
Hs 578Bst CTRP2 4.5102 14.3747 -0.073 21.3973
CAL-85-1 GDSC2; CTRP2 4.5295 41.3739 -13.5512 36.1752
HCC2218 GDSC1; GDSC2; CTRP2 4.897 23.7883 -4.4507 27.5718
HCC1500 GDSC1; GDSC2; CTRP2 4.9805 29.8533 -7.4133 29.9069
HDQ-P1 GDSC2; CTRP2 5.4397 13.7743 1.0043 11.7272
CAMA-1 GDSC2; CTRP2 5.4687 21.9102 -3.0376 21.9964
HCC202 CTRP2 5.5413 46.0104 -15.026 39.4453
JIMT-1 GDSC2; CTRP2 5.702 8.3718 3.8918 2.6988
KPL-1 CTRP2 6.1995 6.8414 4.8391 0.037
HCC1806 GDSC2; CTRP2 7.9267 9.2518 4.6239 0.0244
T-47D GDSC2; CTRP2 8.097 27.0471 -3.5281 19.6145
ZR-75-30 GDSC2; CTRP2 8.2609 28.3617 -4.0542 20.4514
BT-20 GDSC2; CTRP2 8.4738 29.3711 -4.3926 20.8391
HCC38 GDSC2; CTRP2 8.5021 30.7673 -5.0614 22.003
HCC1937 GDSC2; CTRP2 8.6019 32.5337 -5.8598 23.2191
BT-474 GDSC1; GDSC2; CTRP2 8.8006 30.8781 -4.8913 21.3659
HCC1569 GDSC2; CTRP2 8.8984 38.2204 -8.4514 28.0609
HCC1395 GDSC2; CTRP2 9.5236 27.7143 -2.8092 16.5096
HCC1428 GDSC2; CTRP2 9.5343 30.0178 -3.9268 18.7695
BT-549 GDSC2; CTRP2 9.5783 40.9503 -9.2842 26.8765
HMC-1-8 CTRP2 9.8342 21.0371 -1.1143 8.3924
MDA-MB-468 GDSC2; CTRP2 10.8656 43.3786 -9.5141 25.8747
MDA-MB-231 GDSC2; CTRP2 12.2641 36.5301 -5.1635 18.2705
BT 145 CTRP2 1.0165 70.9723 -31.3335 47.2849
BT 231 CTRP2 1.9874 32.7975 -11.4554 42.3136
BT 248 CTRP2 2.8398 17.3211 -3.0158 32.5106
BT164 CTRP2 6.361 55.6491 -19.1694 40.3795
BT 320 CTRP2 6.3716 7.5998 4.6315 0.3314
BT 340 CTRP2 6.4322 8.1653 4.4325 0.8346
BT 416 CTRP2 6.4599 8.3774 4.3573 1.0479
BT 498 CTRP2 6.498 8.1686 4.4632 0.6982
BT 245 CTRP2 6.9827 14.9977 1.5761 11.004
BT 482 CTRP2 7.043 9.0471 4.3625 0.644
BT 187 CTRP2 7.4108 35.1941 -8.1066 31.8748
BT 271 CTRP2 8.2341 24.9748 -2.4035 21.2067
BT 239 CTRP2 8.2863 39.1428 -9.3841 32.1184
BT 172 CTRP2 8.5173 35.694 -7.4911 29.6754
BT 428 CTRP2 8.8931 25.442 -2.152 19.6368
BT 228 CTRP2 9.1023 34.1386 -6.2749 27.2464
BT 422 CTRP2 9.7412 44.3491 -10.8441 31.8428
BT147 CTRP2 9.9106 26.2305 -1.8186 17.4041
BT 159 CTRP2 10.1574 49.1499 -12.9057 33.1587
BT 232 CTRP2 10.2034 26.863 -1.9224 17.2817
BT 286 CTRP2 10.2164 35.7721 -6.2512 25.7953
BT 359 CTRP2 10.6826 44.0744 -9.9942 29.9719
BT 131 CTRP2 10.6991 32.5974 -4.3513 21.959
BT 330 CTRP2 10.9562 38.9076 -7.2487 26.3579
BT 139 CTRP2 11.0237 39.2656 -7.375 26.4538
BT 112 CTRP2 11.5913 36.6288 -5.6802 23.2398
BT 333 CTRP2 12.1885 30.5041 -2.3377 15.8831
BT 216 CTRP2 12.1929 32.4928 -3.2769 17.9943
BT 504 CTRP2 12.1997 28.6475 -1.4606 13.7074
BT 328 CTRP2 13.0668 29.6789 -1.4028 12.6307
BT 444 CTRP2 13.0669 29.471 -1.3073 12.3866
BT 179 CTRP2 13.8799 58.7005 -14.8236 31.1615
BT 440 CTRP2 14.1898 43.8317 -7.3583 23.0306
BT 224 CTRP2 16.3309 43.7299 -5.8959 18.702
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 12.6503 30.5712 -2.0741 14.7391
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -6.8123 3.4174 -9.9096 37.736
H4 GDSC2 -6.572 5.5397 -12.0267 33.3824
MOG-G-UVW GDSC2 -2.9863 8.3382 -10.5629 19.9313
AM-38 GDSC1; GDSC2; CTRP2 -2.1392 6.1413 -3.1201 36.8059
KINGS-1 GDSC1; GDSC2 -1.8837 19.681 -13.6479 32.0977
LNZTA3WT4 GDSC2 -0.9479 14.3497 -12.0495 20.7389
GI-1 GDSC1; GDSC2 -0.7798 12.0821 -9.0216 20.152
Onda 10 GDSC1; GDSC2 -0.6401 25.9533 -15.789 34.8706
NMC-G1 GDSC1; GDSC2 -0.5307 20.5513 -13.0196 31.1453
D-566MG GDSC2 -0.4753 10.727 -8.1385 19.1618
Onda 11 GDSC1; GDSC2 -0.4061 20.5308 -12.914 30.7584
M059J GDSC2 -0.3347 27.358 -17.9563 30.861
D-423MG GDSC2 -0.3235 6.2596 -5.9041 9.0174
PFSK-1 GDSC2 -0.2298 28.4606 -18.4213 31.2782
MOG-G-CCM GDSC2 -0.1901 10.6632 -9.8253 12.0536
D-263MG GDSC1; GDSC2 0.0174 8.5879 -6.7769 10.6669
LN-405 GDSC2 0.0871 11.017 -9.8216 11.6232
D-392MG GDSC2 0.135 15.8679 -12.0489 18.9485
SK-MG-1 GDSC2 0.1387 2.5438 -6.4054 0.0556
D-245MG GDSC2 0.1471 10.6618 -7.6768 16.1534
D-247MG GDSC1; GDSC2 0.2811 4.2208 -4.6811 2.2542
D-336MG GDSC1; GDSC2 0.2878 15.4585 -9.9002 23.1761
D-542MG GDSC2 0.5175 21.8147 -12.8517 29.0736
D-502MG GDSC1; GDSC2 0.527 8.7731 -6.5422 10.6039
KNS-81-FD GDSC1; GDSC2 1.1224 19.8398 -11.4403 25.3746
SNU-738 CTRP2 3.9934 10.0823 1.6036 16.5085
SNU-626 CTRP2 4.0056 8.3274 2.4732 12.9845
SNU-489 CTRP2 5.3292 14.9829 0.3104 18.4685
LN-18 GDSC2; CTRP2 5.9325 10.1095 3.2084 4.4788
SF268 GDSC1; GDSC2; CTRP2 5.9989 21.1017 -2.2033 19.4327
SF295 GDSC2; CTRP2; CTRP1 6.3609 38.1024 -10.2876 33.2441
YKG-1 GDSC2; CTRP2 6.4614 42.9355 -12.7336 34.9264
KNS-81 CTRP2 6.5004 17.4651 0.0018 17.3421
SNU-201 CTRP2 6.5527 12.3839 2.5431 8.447
SNU-466 CTRP2 6.6717 7.8371 4.6645 0.1607
SW1088 GDSC2; CTRP2 7.0307 52.4172 -17.0078 35.7943
8-MG-BA GDSC1; GDSC2; CTRP2 7.4042 8.8975 4.5628 0.1006
Daoy GDSC2; CTRP2 8.378 27.6901 -3.6346 19.4973
Hs 683 GDSC2; CTRP2 8.6403 51.3472 -15.1827 34.4103
SF539 GDSC1; GDSC2; CTRP2 9.102 35.3559 -6.8769 24.2203
SW1783 GDSC2; CTRP2 9.5586 25.6008 -1.7582 14.1298
Becker GDSC1; GDSC2; CTRP2 9.9345 57.7451 -17.3498 33.4711
LN-229 GDSC2; CTRP2; CTRP1 9.9404 22.1663 0.2752 9.24
U-118MG GDSC2; CTRP2 9.9758 40.3299 -8.6761 25.735
42-MG-BA GDSC2; CTRP2 10.2464 46.7158 -11.6307 28.7338
KG-1-C CTRP2 10.2605 30.0598 -3.428 20.67
KNS-60 CTRP2 10.3129 30.8909 -3.7949 21.3587
DK-MG GDSC2; CTRP2 10.334 43.6344 -10.0391 26.9903
U-251MG GDSC2; CTRP2 10.338 24.5602 -0.733 10.8944
YH-13 GDSC2; CTRP2 10.5087 44.494 -10.3322 27.1453
D283 Med GDSC1; GDSC2; CTRP2 10.9237 26.7095 -1.3675 11.857
A-172 GDSC2; CTRP2 11.7487 38.9284 -6.6874 21.2325
CAS-1 GDSC1; GDSC2; CTRP2 11.7795 36.8798 -5.6696 19.5886
GaMG GDSC2; CTRP2; CTRP1 12.2244 49.4 -11.347 26.8768
ONS-76 GDSC1; GDSC2; CTRP2 12.691 33.8906 -3.612 15.022
SNU-1105 CTRP2 12.75 29.8634 -1.6824 13.6694
KNS-42 GDSC1; GDSC2; CTRP2 12.8443 35.129 -4.0994 17.0136
DBTRG-05MG GDSC2; CTRP2 13.0577 26.3006 0.1179 6.6008
U-87MG ATCC GDSC1; GDSC2; CTRP2 13.1762 46.2497 -9.2374 23.4158
SNB-75 GDSC1; GDSC2; CTRP2 13.3378 48.808 -10.3698 25.8133
GB-1 GDSC1; GDSC2; CTRP2 13.5215 34.0446 -3.1466 13.3736
KALS-1 GDSC1; GDSC2; CTRP2 13.7927 50.5828 -10.9098 24.8326
M059K CTRP2 13.9094 52.9639 -11.9891 28.7328
SF126 GDSC1; GDSC2; CTRP2 14.6522 31.8912 -1.4695 9.8283
GOS-3 CTRP2 14.7073 48.8885 -9.4404 25.2656
CCF-STTG1 CTRP2 14.9835 41.5788 -5.752 19.7381
GMS-10 CTRP2 15.4717 39.9148 -4.6561 17.3227
T98G GDSC2; CTRP2 15.6289 43.4112 -6.1977 17.0556
TM-31 CTRP2 16.5924 37.3862 -2.818 12.6071
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 -7.7059 0.1266 -9.3471 40.1205
ETK-1 GDSC1; GDSC2 -7.1567 2.1773 -9.6794 38.5469
TGBC24TKB GDSC1; GDSC2 -5.9959 -0.0392 -7.5066 28.1284
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -1.7773 74.9043 -35.6189 49.5712
MFE-319 GDSC2; CTRP2; CTRP1 -1.2279 9.715 -3.4078 35.4286
JHUEM-7 CTRP2 -0.97 145.1199 -70.0664 49.4401
MFE-280 GDSC2 -0.3949 5.8728 -7.839 4.081
HEC-265 CTRP2; CTRP1 2.1934 6.6069 1.4532 22.5063
MFE-296 GDSC2; CTRP2 2.3833 52.4869 -20.9293 41.8099
HEC-151 CTRP2; CTRP1 3.3306 15.257 -1.4548 28.5546
HEC-108 CTRP2; CTRP1 3.511 15.6257 -1.474 28.1857
HEC-251 CTRP2; CTRP1 4.2336 11.3461 1.2942 17.9784
HEC-6 CTRP2; CTRP1 4.7232 19.768 -2.479 27.9121
RL95-2 GDSC1; GDSC2; CTRP2 5.1961 47.3613 -15.9878 36.9698
AN3-CA GDSC2; CTRP2 5.6726 35.1156 -9.471 31.4079
JHUEM-3 CTRP2 6.2058 37.1348 -10.0435 35.3908
HEC-1-A CTRP2 6.3565 22.694 -2.7122 24.9284
HEC-59 CTRP2; CTRP1 7.1187 34.1679 -7.711 32.1053
KLE GDSC1; GDSC2; CTRP2; CTRP1 7.8663 24.7385 -2.4389 18.04
HEC-1-B CTRP2 8.2087 31.9969 -5.8941 27.8806
JHUEM-1 CTRP2 8.2089 32.7818 -6.2834 28.4554
ESS-1 GDSC2; CTRP2 10.4411 37.8061 -7.0853 23.1162
EFE-184 CTRP2 10.5771 26.855 -1.666 16.1534
HEC-50B CTRP2 14.3255 41.32 -6.0636 20.909
EN GDSC2; CTRP2 15.2415 47.5166 -8.4119 20.5983
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 1.2071 6.3684 0.478 28.8298
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC2 -4.4649 18.4498 -15.1743 41.0623
KTCTL-26A GDSC2 -1.5133 21.0066 -14.0138 34.2928
LB996-RCC GDSC1; GDSC2 -1.0653 23.4442 -14.874 32.402
BB65-RCC GDSC1; GDSC2 -0.7666 10.0659 -8.0241 19.357
TK-10 GDSC1; GDSC2 -0.3385 9.6471 -7.52 14.1921
UO-31 GDSC2; CTRP2 -0.2861 21.4276 -7.9249 41.0298
KTCTL-21 GDSC2 -0.2252 9.4462 -7.346 15.5417
NCC021 GDSC2 -0.1956 7.1883 -6.2562 10.5343
NCC010 GDSC2 -0.1623 5.4706 -5.4478 6.429
LB2241-RCC GDSC1; GDSC2 -0.1582 3.7476 -4.698 2.7694
SW156 GDSC2 -0.1541 16.6237 -10.7936 26.2324
LB1047-RCC GDSC1; GDSC2 -0.1185 20.2783 -12.5703 29.6833
KTCTL-1M GDSC2 -0.093 17.0095 -10.9383 26.4436
SN12C GDSC2 -0.0236 2.7379 -6.5222 0.1433
SW13 GDSC2 0.1194 9.1949 -8.9893 8.2649
KTCTL-195 GDSC2 0.1242 20.9481 -14.4937 24.7644
RXF 393L GDSC1; GDSC2 0.1298 21.9502 -13.2093 30.3043
KTCTL-13 GDSC2 0.2177 11.0984 -7.8381 16.6446
HA7-RCC GDSC1; GDSC2 0.4168 14.2791 -9.2349 21.0328
A-704 GDSC1; GDSC2 2.7045 28.1823 -14.3778 26.356
TUHR4TKB CTRP2 4.8967 5.6885 4.5923 2.2059
CAL-54 GDSC2; CTRP2 7.012 35.9117 -8.7817 29.0652
TUHR10TKB CTRP2 7.3803 19.7994 -0.4884 17.4078
OS-RC-2 GDSC1; GDSC2; CTRP2 7.5422 42.3609 -11.5753 31.3648
TUHR14TKB CTRP2 7.8519 27.6517 -4.0133 25.2018
VMRC-RCZ GDSC2; CTRP2 7.8692 26.5583 -3.4587 19.7462
786-O GDSC2; CTRP2 7.9847 14.4599 2.5031 4.4739
KMRC-1 GDSC2; CTRP2 8.6362 39.3183 -9.1989 27.7555
KMRC-3 CTRP2 8.6473 45.0841 -12.0578 34.096
VMRC-RCW GDSC2; CTRP2; CTRP1 9.203 17.9617 1.7745 6.6642
A-498 GDSC1; GDSC2; CTRP2 9.633 24.4963 -1.1741 12.6675
SNU-1272 CTRP2 10.0731 31.6388 -4.3304 22.7147
BFTC-909 GDSC2; CTRP2 10.1224 30.6578 -3.8166 17.9271
KMRC-20 GDSC2; CTRP2 12.8391 26.5622 -0.1225 7.3155
Caki-2 CTRP2 13.8927 27.5264 0.0395 8.0265
769-P GDSC2; CTRP2 14.0393 31.0985 -1.4692 9.4473
ACHN GDSC2; CTRP2 14.4802 30.1091 -0.7722 7.609
KMRC-2 CTRP2 14.7056 52.4276 -11.1582 27.1817
Caki-1 GDSC2; CTRP2 14.8084 34.8967 -2.7427 12.478
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 16.2637 32.7142 -0.7899 6.8936
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CaR-1 GDSC2 -0.412 3.1676 -6.8056 0.6445
DiFi GDSC2 -0.3535 12.2699 -10.6692 15.4083
HCC2998 GDSC2 -0.2926 11.5849 -10.312 14.0408
SNU-C1 GDSC1; GDSC2; CTRP2 -0.0291 18.8247 -6.4251 36.6063
COLO 320HSR GDSC1; GDSC2 0.0639 6.5617 -5.8084 6.5304
SW626 GDSC2 0.1809 5.9095 -7.587 2.6006
SW837 GDSC2 0.1824 2.6743 -6.4333 0.0666
GP5d GDSC2 0.2231 3.3026 -6.6259 0.2121
SW1116 GDSC2 0.2665 2.6219 -6.3891 0.0433
SNU-283 GDSC2 0.5414 3.0894 -4.1463 0.4086
NCI-H747 GDSC1; GDSC2; CTRP2 0.8219 22.9951 -7.654 36.395
SW1463 GDSC2 0.8338 3.4671 -6.4773 0.0539
SNU-C2B GDSC1; GDSC2 1.8065 14.0258 -8.1852 13.2195
LS513 GDSC1; GDSC2; CTRP2; CTRP1 2.3716 8.5806 0.8185 17.8445
T84 GDSC2; CTRP2 2.6605 16.9641 -3.0026 26.2953
SW48 CTRP2; CTRP1 3.3608 8.5842 1.8113 18.0477
DLD-1 CTRP1 4.2335 13.5915 0.1797 36.3035
SW948 GDSC2; CTRP2; CTRP1 4.2977 33.0023 -9.4539 33.3551
COLO205 GDSC2; CTRP2; CTRP1 4.3132 5.2835 4.2102 4.5668
LS411N GDSC1; GDSC2; CTRP2; CTRP1 4.4538 13.7785 0.28 15.846
COLO 320 CTRP2; CTRP1 4.5841 17.0562 -1.2428 25.2679
KM12 GDSC1; GDSC2; CTRP2; CTRP1 4.7312 6.4684 4.1475 3.9523
HCT 116 GDSC2; CTRP2; CTRP1 4.8872 7.1103 3.9787 4.2042
SNU-C4 CTRP2; CTRP1 5.2005 15.4722 0.0706 20.2039
CW-2 GDSC1; GDSC2; CTRP1 5.4936 7.2245 4.4278 2.0017
LS1034 GDSC1; GDSC2; CTRP2 5.6215 31.1004 -7.5059 29.1909
HCT 8 CTRP2; CTRP1 5.8643 12.994 1.8485 12.6104
HCC-56 CTRP2 5.9158 7.0773 4.6294 0.6197
HT-29 GDSC2; CTRP2; CTRP1 6.0872 11.6665 2.6801 6.5253
SNU-61 CTRP2; CTRP1 6.1487 10.6819 3.2111 6.6726
CCK-81 GDSC2; CTRP2 6.4181 9.4708 3.8444 2.1276
SNU-175 GDSC2; CTRP1 6.794 17.7945 0.1838 12.8909
SK-CO-1 GDSC2; CTRP2; CTRP1 6.8341 18.2604 -0.0164 13.3845
CL-40 CTRP1 7.041 15.8732 1.3163 22.1473
LoVo GDSC2; CTRP2; CTRP1 7.0776 40.9679 -11.1378 31.6825
CL-34 CTRP1 7.1586 16.0609 1.31 21.8234
SW403 CTRP1 7.2215 24.0198 -2.576 32.9785
HCT 15 GDSC2; CTRP2 7.3616 35.3469 -8.2217 27.9872
SNU-81 GDSC2; CTRP2; CTRP1 7.4105 19.8591 -0.3717 15.0725
SNU-C2A CTRP2; CTRP1 7.6077 24.6949 -2.6139 23.1384
SW480 CTRP1 7.7144 24.4928 -2.4325 31.5716
NCI-H716 GDSC1; GDSC2; CTRP2 7.8961 26.3435 -3.332 19.4562
SW1417 GDSC2; CTRP2 8.1551 42.1163 -10.9672 30.1516
RCM-1 [Human ESC] GDSC2; CTRP2; CTRP1 8.177 14.5205 2.7332 4.2378
OUMS-23 CTRP2 8.2513 16.5709 1.6845 9.3575
LS180 GDSC2; CTRP2; CTRP1 8.7086 20.4892 0.2526 10.5201
GP2d CTRP2; CTRP1 8.8777 29.4091 -3.9859 24.0785
SNU-1040 CTRP1 9.5493 21.2082 0.4734 19.258
C2BBe1 GDSC1; GDSC2; CTRP2; CTRP1 9.7363 39.071 -8.1126 25.5443
CL-11 GDSC1; GDSC2; CTRP2 10.3006 39.2555 -7.9027 24.4021
SNU-1033 CTRP2 10.6206 35.7818 -5.9612 24.8496
NCI-H508 GDSC2; CTRP2; CTRP1 10.6505 39.124 -7.4545 25.1289
SNU-407 GDSC2; CTRP2 10.7459 41.3728 -8.6149 24.8905
SNU-C5 GDSC2; CTRP2; CTRP1 10.8752 35.0917 -5.3134 20.234
HT115 GDSC2; CTRP2; CTRP1 11.2391 24.5305 -0.0079 9.7111
COLO 678 GDSC2; CTRP2; CTRP1 11.4453 27.5867 -1.3069 11.693
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 11.4809 64.8402 -19.5542 33.6948
SNU-503 CTRP2 11.8088 35.5337 -4.9973 21.8127
HT-55 GDSC2; CTRP2; CTRP1 12.0216 26.9685 -0.6529 9.6661
COLO201 CTRP2 12.2372 50.8087 -12.155 30.4619
SW620 GDSC2; CTRP2; CTRP1 13.2925 34.3923 -3.3208 14.3096
LS123 GDSC1; GDSC2; CTRP2; CTRP1 13.3443 51.6621 -11.6354 26.2057
RKO GDSC1; GDSC2; CTRP2; CTRP1 14.982 32.6997 -1.4985 9.2292
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 0.4404 2.3463 -3.9288 0.0917
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC2 -0.7546 12.146 -10.8687 16.7577
JHH-7 GDSC2 0.0524 3.3163 -6.6895 0.3183
Huh-7 GDSC2 0.1602 11.319 -9.9155 11.8725
Hep-G2/C3A GDSC2 0.5001 2.2828 -6.2064 0.0042
SNU-886 CTRP2 3.2102 19.9258 -3.9752 33.3509
SNU-878 CTRP2 4.3599 24.3123 -5.1657 32.9011
JHH-5 CTRP2 4.4967 11.2675 1.4654 15.9481
HuH-6 CTRP2 5.1037 31.7442 -8.2561 35.314
JHH-6 GDSC2; CTRP2; CTRP1 5.218 6.2244 4.7091 1.5045
SNU-423 GDSC2; CTRP2 6.477 27.5241 -5.0251 24.402
HuH-1 GDSC2; CTRP2 6.9453 8.4018 4.5664 0.1774
SNU-182 CTRP2 7.3782 40.1054 -10.5812 34.358
Hep 3B2.1-7 GDSC2; CTRP2 7.4296 8.8466 4.5895 0.086
Hep-G2 CTRP2; CTRP1 7.7658 18.9599 0.3308 14.875
SNU-398 GDSC2; CTRP2; CTRP1 7.9253 38.7091 -9.3343 28.9365
Li-7 CTRP2 8.1135 53.1917 -16.5218 37.5227
SNU-761 CTRP2 9.1133 41.0508 -9.6904 31.4352
JHH-2 GDSC2; CTRP2 10.0022 39.4663 -8.2297 25.1382
SNU-387 GDSC2; CTRP2 10.1038 24.8775 -1.0386 11.8658
JHH-1 GDSC2; CTRP2 10.8402 20.6861 1.3624 5.2006
SNU-449 GDSC2; CTRP2; CTRP1 11.692 42.5467 -8.3708 23.9446
JHH-4 GDSC2; CTRP2 12.2202 27.5524 -0.9402 9.7086
SNU-475 CTRP2 12.5594 40.7204 -6.9851 24.1839
PLC/PRF/5 CTRP2 12.7901 43.0643 -7.961 25.3017
SK-HEP-1 GDSC2; CTRP2 15.1702 31.6831 -1.0831 7.8069
HLF CTRP2 15.9617 44.3529 -6.4263 19.9066
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 227 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H720 GDSC1; GDSC2 -4.6666 5.3274 -8.8127 28.3372
NCI-H1304 GDSC1 -4.0365 0.6922 -5.9517 22.5861
EBC-1 GDSC2; CTRP2; CTRP1 -3.3387 12.7451 -6.8796 44.5537
SBC-1 GDSC1; GDSC2 -2.47 13.7817 -11.1746 31.8306
NCI-H520 GDSC2; CTRP2 -2.3072 20.6269 -9.4839 43.4389
NCI-H209 GDSC1; GDSC2; CTRP2 -2.2577 10.8848 -5.0315 39.8905
COR-L32 GDSC2 -1.249 13.4748 -10.0614 26.69
NCI-H146 GDSC2; CTRP2 -1.2385 28.5325 -12.2736 44.8922
NCI-H1648 GDSC1; GDSC2 -1.1181 8.9251 -7.72 16.3581
NCI-H2373 GDSC2 -0.9994 6.6399 -8.4832 7.6264
Lu-139 GDSC1; GDSC2 -0.9407 13.3794 -9.7807 22.6446
UMC-11 GDSC2 -0.8842 13.7857 -11.7354 19.7238
DMS 454 CTRP2 -0.8501 9.3183 -7.4293 23.8407
CPC-N GDSC1; GDSC2 -0.8435 7.1451 -6.6617 11.6057
DMS 53 GDSC2; CTRP2 -0.8322 16.9167 -6.2938 38.0465
NCI-H524 GDSC1; GDSC2 -0.7014 7.7444 -6.8528 12.1633
NCI-H748 GDSC1; GDSC2 -0.6995 8.1975 -7.0697 15.3259
NCI-H2066 GDSC2 -0.5514 11.8512 -10.5989 15.4872
NCI-H250 GDSC2 -0.5201 16.5556 -11.0332 27.4676
EMC-BAC-2 GDSC2 -0.5189 15.6344 -12.3743 20.9036
SBC-3 GDSC2 -0.3955 17.8614 -13.3621 23.1588
NCI-H1993 GDSC2 -0.3827 39.7735 -24.1308 36.4209
LC-2/ad GDSC1; GDSC2 -0.3787 16.1303 -10.7174 26.4891
NCI-H513 GDSC2 -0.3787 10.8851 -10.0414 13.173
COR-L303 GDSC2 -0.3571 13.7268 -9.5194 23.3809
NCI-H2461 GDSC2 -0.3515 12.5224 -10.7862 15.8073
NCI-H2591 GDSC2 -0.2414 14.7881 -11.7843 18.7906
NCI-H290 GDSC2 -0.2377 7.2846 -6.328 10.9604
NCI-H211 GDSC1; GDSC2; CTRP2 -0.1768 37.0015 -15.4698 42.7327
NCI-H2869 GDSC2 -0.1629 2.472 -4.1954 0.8339
EMC-BAC-1 GDSC2 -0.1482 11.0843 -8.0822 18.2845
NCI-H345 GDSC1; GDSC2 -0.1414 1.6518 -3.8959 0.1646
COR-L311 GDSC2 -0.1312 7.6367 -8.4478 6.3287
NCI-H3122 GDSC2 -0.0995 15.5489 -12.0521 19.3315
NCI-H2804 GDSC2 -0.0908 5.5789 -5.4553 6.3557
NCI-H187 GDSC1 -0.0805 10.0979 -7.5605 18.4506
RERF-LC-Sq1 GDSC2 -0.0488 12.0626 -10.3825 13.9118
A-427 GDSC2 -0.0327 3.399 -4.4968 1.7971
NCI-H740 GDSC2 -0.0209 15.6302 -10.2075 24.567
NCI-H2135 GDSC1; GDSC2 -0.0164 2.6426 -4.1996 0.7661
NCI-H2803 GDSC2 0.0115 5.3127 -5.2797 5.3277
NCI-H2227 GDSC2 0.0131 22.7294 -13.6833 31.2161
Calu-3 GDSC2; CTRP2; CTRP1 0.0158 18.172 -5.9832 36.335
LC-1/sq GDSC2 0.0316 11.4638 -10.0582 12.6011
NCI-H2171 GDSC1; GDSC2 0.0537 13.4632 -9.0947 21.3039
IST-SL1 GDSC1; GDSC2 0.0645 10.543 -7.6756 16.3093
NCI-H1436 GDSC1; GDSC2 0.0652 5.8715 -5.497 6.3263
ABC-1 GDSC2 0.0676 4.427 -4.8692 3.2912
NCI-H2818 GDSC2 0.1302 12.4694 -10.4604 13.913
Ms-1 GDSC1; GDSC2 0.1438 2.1401 -3.9617 0.1613
NCI-H2795 GDSC2 0.1468 23.1017 -15.5233 26.6284
NCI-H1048 GDSC2; CTRP1 0.1749 5.1456 -0.2676 25.2877
LB647-SCLC GDSC1; GDSC2 0.1762 14.7892 -9.6536 22.7108
NCI-H2722 GDSC2 0.1794 10.0037 -9.313 9.4962
NCI-H1651 GDSC2 0.2202 2.541 -6.378 0.041
NCI-H2347 GDSC2 0.2244 9.4589 -9.0474 8.3634
NCI-H1770 GDSC1; GDSC2 0.2424 1.9499 -3.8645 0.079
NCI-H510A GDSC1; GDSC2 0.2457 10.246 -7.4126 14.9014
PaCa-3 GDSC2 0.2614 3.9416 -6.8293 0.4863
NCI-H2731 GDSC2 0.2677 20.6414 -14.2456 24.0479
NCI-H2595 GDSC2 0.2847 2.3464 -6.2951 0.017
NCI-H2369 GDSC2 0.3631 2.4954 -6.3175 0.0199
Lu-99A GDSC2 0.41 8.7597 -8.6458 6.4986
Lu-135 GDSC2 0.4249 5.1243 -7.1881 1.2098
NCI-H1688 GDSC2 0.433 12.6362 -10.3532 13.0767
NCI-H64 GDSC1; GDSC2 0.4514 9.4151 -6.8876 10.4482
NCI-H2810 GDSC2 0.5056 3.2639 -4.2215 0.5833
NCI-H847 GDSC1; GDSC2 0.5351 12.0069 -8.0592 14.7064
LK-2 GDSC2 0.5579 2.7595 -6.3394 0.0206
Lu-165 GDSC1; GDSC2 0.5869 8.1795 -6.2339 7.6064
COR-L279 GDSC2; CTRP2; CTRP1 0.612 11.4656 -2.26 29.097
NCI-H1184 CTRP2 0.6456 35.2741 -13.8764 45.1783
Lu-134-A GDSC1; GDSC2 0.6574 13.2051 -8.5504 18.3852
NCI-H69 GDSC1; GDSC2 0.7046 11.1792 -7.5541 12.6234
NCI-H1944 GDSC2; CTRP2; CTRP1 0.7271 16.9656 -4.7226 33.286
COR-L321 GDSC2 0.7841 13.5649 -8.637 18.4436
NCI-H835 GDSC2 0.7973 3.5273 -6.5085 0.0697
NCI-H1734 GDSC2; CTRP2 0.8461 14.9348 -4.8142 30.4242
IST-SL2 GDSC1; GDSC2 0.9184 13.8423 -8.6792 18.3398
NCI-H1568 GDSC2; CTRP2; CTRP1 0.9355 28.6815 -10.2544 38.6861
DMS 114 GDSC1; GDSC2; CTRP2 1.0471 21.1471 -6.5404 34.7808
COR-L105 GDSC2; CTRP2 1.2192 29.8825 -10.6907 38.3594
EPLC-272H GDSC2; CTRP2; CTRP1 1.4303 23.0538 -7.0294 35.0038
NCI-H128 GDSC1 1.7638 11.5559 -7.0714 12.5624
NCI-H322M GDSC1; GDSC2 2.0823 20.2509 -10.9651 20.6973
NCI-H1975 GDSC1; GDSC2; CTRP1 2.1569 26.4329 -8.0424 34.9333
DMS 273 GDSC2; CTRP2; CTRP1 2.1773 20.3378 -5.0096 31.0991
KNS-62 GDSC2; CTRP2; CTRP1 2.3059 12.6243 -1.1282 23.1784
NCI-H1876 GDSC1; GDSC2; CTRP1 2.3265 10.7746 -0.2312 20.8211
NCI-H810 GDSC2; CTRP2; CTRP1 2.3676 26.9173 -8.0951 34.6691
VMRC-LCD GDSC2; CTRP2; CTRP1 2.5075 24.6053 -6.823 33.0282
NCI-H1581 GDSC1; GDSC2; CTRP2 2.5415 16.2033 -2.7372 25.9497
NCI-H2106 CTRP2 2.8674 22.5928 -5.6041 36.3087
Lu-99 CTRP2; CTRP1 2.9595 14.0283 -1.1914 28.786
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 3.2154 12.4056 -0.1608 19.0588
NCI-H1793 GDSC2; CTRP2; CTRP1 3.2434 37.809 -12.7564 37.324
NCI-H23 GDSC1; GDSC2; CTRP2; CTRP1 3.2729 11.9696 0.1054 18.232
HCC78 GDSC2; CTRP2; CTRP1 3.2968 7.0108 2.4554 11.457
NCI-H1385 CTRP2 3.418 8.8953 1.6388 17.7205
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 3.5837 26.2029 -6.6711 31.2087
NCI-H1930 CTRP1 3.6066 28.3065 -7.7005 45.8239
NCI-H1105 GDSC2; CTRP2; CTRP1 3.6366 12.5784 0.1441 19.5697
NCI-H1838 GDSC1; GDSC2; CTRP2 3.766 22.4502 -4.7456 27.7345
NCI-H82 GDSC1; GDSC2; CTRP1 3.8622 5.3203 3.7074 6.8649
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 3.9484 15.739 -1.1399 20.4078
NCI-H2029 GDSC2; CTRP2; CTRP1 4.0135 12.5949 0.4782 17.8651
NCI-H358 GDSC2; CTRP2; CTRP1 4.1092 19.571 -2.9077 24.184
RERF-LC-Ad1 CTRP2 4.1403 13.8628 -1.4745 18.265
NCI-H2444 GDSC2; CTRP2 4.1797 18.28 -2.3071 24.4738
NCI-H1693 GDSC2; CTRP2 4.2216 21.3761 -3.8169 25.3772
NCI-H526 GDSC1; GDSC2; CTRP2 4.2233 20.1464 -3.2013 24.1628
NCI-H1341 GDSC2; CTRP2 4.2611 26.184 -6.185 29.238
COR-L88 GDSC1; GDSC2; CTRP1 4.3018 8.6388 2.69 9
NCI-H1155 GDSC1; GDSC2; CTRP2 4.333 18.6108 -2.3404 22.1485
HCC33 GDSC1; GDSC2; CTRP1 4.4143 12.3523 0.9555 15.6613
NCI-H1373 CTRP2; CTRP1 4.4645 12.7954 0.7791 19.3435
MOR/CPR CTRP2 4.5673 5.3165 2.8148 0.0307
NCI-H2196 GDSC1; GDSC2; CTRP2 4.5821 23.8106 -4.7267 28.5427
SCLC-21H CTRP1 4.6247 7.9779 3.3121 19.3631
NCI-H2087 GDSC2; CTRP2 4.6693 21.2136 -3.3549 23.8027
HCC4006 CTRP2; CTRP1 4.7304 13.9546 0.4315 19.9765
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2; CTRP1 4.7306 16.3948 -0.7871 18.304
LK2 CTRP2 4.8493 5.3293 4.7186 1.7994
NCI-H2126 CTRP2; CTRP1 4.9857 18.1551 -1.4507 24.9886
HCC44 GDSC2; CTRP2; CTRP1 5.0256 25.52 -5.0994 26.8455
NCI-H596 GDSC2; CTRP1 5.1088 31.9274 -8.2335 31.0202
HCC1359 CTRP1 5.2038 5.9392 4.8399 3.3543
NCI-H1573 GDSC2; CTRP2; CTRP1 5.2054 18.7533 -1.5659 19.5435
A-549 GDSC2; CTRP2; CTRP1 5.2087 18.9659 -1.6694 19.7855
LCLC-97TM1 GDSC2; CTRP2; CTRP1 5.2132 23.5591 -3.9622 24.6078
COR-L23 GDSC2; CTRP1 5.3224 12.9051 1.4554 11.1826
NCI-H1694 GDSC1; CTRP2; CTRP1 5.3341 22.4265 -3.2954 27.0131
NCI-H3255 GDSC2; CTRP1 5.4162 27.3488 -5.6884 29.1419
NCI-H889 CTRP2 5.4569 8.6428 3.5764 5.4187
HCC1588 CTRP2 5.5569 8.4331 2.9828 2.6244
CAL-12T GDSC2; CTRP2; CTRP1 5.6634 11.4907 2.4387 8.7527
NCI-H2170 GDSC2; CTRP2 5.6852 43.489 -13.6465 34.9886
SK-MES-1 GDSC2; CTRP2 5.7101 33.4601 -8.6125 30.4218
NCI-H2122 GDSC2; CTRP2; CTRP1 5.7844 11.1406 2.7083 6.815
NCI-H1623 GDSC2; CTRP2 5.8164 35.5725 -9.5812 31.3506
NCI-H1435 GDSC2; CTRP2; CTRP1 5.8741 26.0475 -4.661 24.9454
RERF-LC-KJ GDSC2; CTRP1 5.8788 26.4735 -4.8701 25.2961
NCI-H1437 GDSC2; CTRP1 5.9563 35.2994 -9.2178 32.7163
NCI-H727 GDSC2; CTRP2; CTRP1 5.977 17.8908 -0.5035 15.7934
NCI-H1355 GDSC1; GDSC2; CTRP2; CTRP1 6.1267 33.8593 -8.3584 29.8933
HCC2935 CTRP2; CTRP1 6.1685 36.9124 -9.8501 35.5101
NCI-H446 GDSC1; GDSC2; CTRP2 6.196 21.8036 -2.3959 19.6032
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 6.2216 28.1598 -5.4335 27.5953
NCI-H460 GDSC2; CTRP2; CTRP1 6.2591 7.6176 4.7267 0.5622
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 6.2837 15.9996 0.6814 12.1494
NCI-H2228 GDSC2; CTRP2 6.3119 25.1619 -3.9785 22.7293
SBC-5 GDSC2; CTRP2 6.4684 7.292 4.7804 0.0402
SW1271 GDSC2; CTRP2 6.5207 26.4232 -4.441 23.3168
NCI-H1650 GDSC1; GDSC2; CTRP2 6.542 15.5916 0.9609 10.433
BEN GDSC2; CTRP1 6.5448 45.7254 -13.9468 35.8723
LCLC-103H GDSC2; CTRP2; CTRP1 6.6068 7.5572 4.9012 0.0805
NCI-H1963 GDSC1; CTRP1 6.6114 22.5076 -2.3008 22.7758
LC-1/sq-SF CTRP2; CTRP1 6.7019 29.3847 -5.658 30.0684
HOP-92 GDSC2; CTRP2 6.8515 23.9144 -2.9301 19.9123
COR-L51 CTRP2; CTRP1 6.8818 21.2732 -1.4748 21.5815
IA-LM GDSC1; GDSC2; CTRP2 7.0368 8.5298 4.5555 0.1708
NCI-H1836 GDSC1; GDSC2; CTRP1 7.1061 18.875 -0.1142 14.7608
NCI-H2291 GDSC2; CTRP2 7.2498 20.0425 -2.2499 13.09
NCI-H1395 CTRP2 7.335 44.1157 -12.6167 35.9893
COR-L95 GDSC1; GDSC2; CTRP2 7.4135 14.7632 1.9895 6.469
PC-14 GDSC2; CTRP2 7.4666 9.4292 4.3961 0.2781
NCI-H2085 GDSC2; CTRP2 7.5094 22.0991 -1.5259 15.8939
HOP-62 GDSC1; GDSC2; CTRP2 7.568 50.4894 -15.6108 34.4475
HCC95 CTRP2 7.6225 15.6562 1.7029 9.5821
ChaGo-K-1 GDSC2; CTRP2; CTRP1 7.6416 25.5177 -2.9958 21.167
DV-90 CTRP2; CTRP1 7.6634 32.1618 -6.2803 29.5399
NCI-H292 GDSC2; CTRP2 7.6842 44.8251 -12.6911 33.5727
NCI-H647 GDSC2; CTRP2 8.0474 34.3323 -7.1783 27.4176
EKVX GDSC1; GDSC2; CTRP2 8.2174 51.3614 -15.5259 35.0339
NCI-H2286 CTRP2; CTRP1 8.2741 65.7871 -22.5648 40.0311
SHP-77 GDSC1; GDSC2; CTRP2; CTRP1 8.3192 20.5908 -0.0689 11.7859
NCI-H1781 GDSC2; CTRP1 8.5034 33.2081 -6.1484 24.12
HCC366 GDSC2; CTRP2 8.603 24.8713 -2.0825 17.3977
NCI-H650 GDSC2; CTRP2; CTRP1 8.686 21.408 -0.2074 11.7477
NCI-H661 GDSC2; CTRP2; CTRP1 8.753 38.7739 -8.7188 27.332
HCC1833 CTRP2; CTRP1 8.8314 38.6244 -8.5839 30.8565
NCI-H2073 CTRP1 8.8522 37.575 -8.0468 36.7434
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 8.8556 28.6423 -3.6245 19.3381
NCI-H1703 GDSC2; CTRP2 8.9822 55.4196 -16.9415 34.0229
LOU-NH91 GDSC2; CTRP2 9.0029 29.1298 -3.8796 19.2647
NCI-H841 GDSC2; CTRP2; CTRP1 9.0915 26.1448 -2.2257 16.1564
NCI-H2009 GDSC2; CTRP2; CTRP1 9.3045 33.6945 -5.781 22.6539
DMS 79 GDSC1; GDSC2; CTRP2 9.3408 27.0467 -2.6142 17.7203
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 9.3689 32.9303 -5.3557 21.8904
LUDLU-1 CTRP2 9.4428 27.5839 -2.8033 20.397
SK-LU-1 GDSC2; CTRP2; CTRP1 9.6837 39.9318 -8.5785 26.1871
NCI-H2405 GDSC2; CTRP2; CTRP1 9.7867 35.1838 -6.1551 22.7222
NCI-H226 GDSC1; GDSC2; CTRP2 9.8761 23.4325 -0.5018 10.7668
NCI-H1755 GDSC2; CTRP2; CTRP1 9.902 28.9069 -2.9927 16.9177
HCC827 GDSC2; CTRP2; CTRP1 10.0094 25.0226 -1.0387 12.4425
NCI-H522 GDSC2; CTRP2; CTRP1 10.1385 41.0027 -8.7637 25.9532
NCI-H1563 GDSC2; CTRP2 10.2326 32.5081 -4.6404 19.3597
SW1573 GDSC2; CTRP2 10.2735 27.7271 -2.2903 14.5955
Sq-1 CTRP2; CTRP1 10.2997 25.1217 -0.8908 14.9812
HCC2279 CTRP2 10.3222 34.9022 -5.7471 24.8743
HCC2108 CTRP2; CTRP1 10.4842 29.4194 -2.8313 19.5418
HCC1438 CTRP2 10.5307 35.6135 -5.944 24.932
NCI-H2110 GDSC2; CTRP2; CTRP1 10.6972 31.2383 -3.5637 18.6021
HCC15 GDSC2; CTRP2; CTRP1 10.8305 34.0983 -4.8606 19.5034
NCI-H1869 GDSC1; GDSC2; CTRP2 11.0132 37.6057 -6.5696 21.7723
NCI-H1792 GDSC2; CTRP2; CTRP1 11.0874 31.9958 -3.6578 17.0279
NCI-H1092 GDSC1; GDSC2; CTRP2 11.7511 30.0679 -2.4165 13.4343
RERF-LC-MS GDSC2; CTRP2 11.841 48.3122 -11.2196 28.0995
NCI-H196 GDSC2; CTRP2 12.0184 38.7833 -6.4256 20.5727
NCI-H441 GDSC2; CTRP2; CTRP1 12.1663 38.4436 -6.0274 20.1341
HCC1171 CTRP2 12.8953 35.8978 -4.432 19.541
NCI-H1339 CTRP2 12.9028 37.655 -5.2679 21.0586
COLO 699 CTRP2; CTRP1 12.9411 33.9973 -3.3633 17.7674
RERF-LC-Ad2 CTRP2 12.9812 55.5619 -13.9437 31.2709
T3M-10 CTRP2; CTRP1 13.091 31.9498 -2.3019 15.2708
NCI-H2030 GDSC2; CTRP2; CTRP1 13.8037 51.4241 -11.1858 26.5147
NCI-H1915 GDSC2; CTRP2; CTRP1 13.9635 38.2687 -4.7174 16.3146
NCI-H322 CTRP2 13.9698 30.4117 -1.1993 11.2149
HCC1195 CTRP2; CTRP1 13.9773 49.8976 -10.316 27.2068
Calu-1 CTRP2 14.0467 42.5767 -6.8529 22.4293
NCI-H2023 GDSC2; CTRP2; CTRP1 14.0676 61.327 -15.8527 29.3235
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 14.2156 33.1276 -2.1492 11.1719
NCI-H838 GDSC2; CTRP2 14.3707 55.5689 -12.93 27.5198
RERF-LC-A1 CTRP2 14.5806 41.3717 -5.9187 20.4149
NCI-H2342 GDSC2; CTRP2; CTRP1 14.5858 45.5938 -7.8037 20.5983
NCI-H2172 GDSC2; CTRP2; CTRP1 14.7477 42.2807 -6.1065 19.0959
Hs 888.Lu CTRP2 2.9531 62.979 -25.6836 45.0924
⏷ Show the Full List of 227 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -4.1996 21.7713 -16.6072 39.272
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.3153 136.2315 -63.6821 48.465
OVK18 GDSC2; CTRP2; CTRP1 -3.1953 12.9253 -6.8073 47.4565
A2780 GDSC2; CTRP2; CTRP1 -3.0394 81.8812 -40.2004 48.6113
OVCAR-3 GDSC2 -0.3459 8.1565 -8.7893 8.0547
Caov-4 GDSC2 0.0127 12.5498 -10.57 14.4803
ES-2 GDSC1; GDSC2 0.7006 22.1712 -12.8912 26.7001
SNU-119 CTRP2 0.7238 28.8523 -10.6276 43.9818
OVKATE GDSC2; CTRP1 2.1557 9.3598 0.2504 19.8307
RMG-I GDSC2; CTRP2; CTRP1 3.0189 22.838 -5.4909 30.4397
RMUG-S CTRP1 4.4464 28.1476 -6.9016 43.7446
OV-90 GDSC2; CTRP2; CTRP1 4.786 16.2767 -0.6809 17.9461
COV434 CTRP2; CTRP1 4.9301 58.4557 -21.6468 42.6139
JHOS-4 GDSC2; CTRP1 5.0363 12.3444 1.4966 12.866
OVCAR-8 GDSC2; CTRP2; CTRP1 5.0658 12.5108 1.4383 11.594
OVTOKO GDSC2; CTRP2 5.596 22.9902 -3.473 22.7109
IGROV-1 GDSC2; CTRP2; CTRP1 5.7066 32.2617 -7.9046 29.8732
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 5.8057 34.1802 -8.7821 30.7662
ES2 CTRP2 6.5175 7.8624 4.5932 0.3518
OAW42 GDSC2; CTRP2; CTRP1 6.5986 7.7836 4.8155 0.19
SNU-840 CTRP2; CTRP1 7.024 123.8747 -52.618 45.599
TOV-112D GDSC2; CTRP2 7.1623 33.0308 -7.2253 26.9192
EFO-27 GDSC2; CTRP2; CTRP1 7.2841 33.1303 -7.0619 28.5194
FU-OV-1 GDSC2; CTRP2 7.3655 24.0752 -2.6127 18.5782
DOV13 GDSC2; CTRP2 7.5821 23.1798 -2.005 16.941
COV318 CTRP1 7.9135 15.2035 2.2464 14.8913
OVMANA CTRP1 8.3369 23.4205 -1.4394 27.9602
OAW28 GDSC2; CTRP2 8.4973 28.7239 -4.0554 20.1786
TYK-nu GDSC2; CTRP2; CTRP1 8.7305 45.1095 -11.8875 30.6599
SNU-8 CTRP2 9.138 43.6741 -10.974 32.6342
JHOM-1 CTRP2; CTRP1 9.1518 43.0492 -10.5337 32.4476
Caov-3 GDSC2; CTRP2; CTRP1 9.5367 47.1724 -12.2839 31.546
JHOC-5 CTRP2; CTRP1 9.609 26.0901 -1.8304 18.3527
OVISE GDSC2; CTRP2 10.354 25.2312 -1.0409 11.6268
OVCAR-5 GDSC2; CTRP2 10.8068 34.701 -5.2991 19.9268
COV644 CTRP2; CTRP1 10.8389 54.6894 -15.0099 34.1938
EFO-21 GDSC2; CTRP2; CTRP1 10.8752 27.058 -1.4304 12.512
COV362 CTRP2; CTRP1 10.8875 47.1797 -11.2519 31.2173
TOV-21G GDSC2; CTRP2 10.9193 31.6756 -3.7499 16.9791
MCAS CTRP2 11.2944 31.439 -3.3774 19.2681
OC 314 GDSC2; CTRP2 11.4202 31.8321 -3.4805 15.9534
OV56 GDSC2; CTRP2 12.0318 24.9671 0.1277 7.3323
ONCO-DG-1 CTRP2 12.2725 32.9482 -3.4408 18.2519
OV7 CTRP2; CTRP1 12.7773 39.4004 -6.0637 22.8706
JHOS-2 GDSC2; CTRP2 13.2526 35.0608 -3.7983 16.0323
HEY A8 CTRP2; CTRP1 13.63 32.7247 -2.3241 14.7526
Kuramochi GDSC1; GDSC2; CTRP2 13.7161 41.2023 -6.4178 19.0095
OVSAHO CTRP2 13.8749 35.4952 -3.6012 16.8439
SK-OV-3 GDSC2; CTRP2; CTRP1 15.325 39.9968 -4.6499 15.0606
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 6.1439 59.6566 -21.3509 41.3246
Aska-SS CTRP2 8.0346 58.6048 -19.2865 38.8867
VA-ES-BJ GDSC1; GDSC2 -6.2334 1.9992 -8.6766 32.8304
SW872 GDSC1; GDSC2 -5.6379 4.3026 -9.2023 32.2851
STS-0421 GDSC2 -1.292 10.045 -8.3983 21.8682
G-401 GDSC2; CTRP2; CTRP1 -0.8833 21.7048 -8.5385 40.4266
Hs 633.T GDSC2 -0.548 26.4291 -17.6569 30.7816
Rh30 GDSC2 -0.2395 11.0785 -10.0455 12.9697
A-204 GDSC2; CTRP2 0.1297 21.4226 -7.5306 37.4733
EW-8 GDSC1; GDSC2 0.2631 1.9958 -3.8727 0.0677
MFH-ino GDSC1; GDSC2 0.3547 21.3673 -12.7525 26.9835
TE 441.T GDSC1; GDSC2 0.9456 12.5288 -8.0353 16.0349
SW684 GDSC1; GDSC2 1.2509 13.2723 -8.1877 14.0385
KYM-1 GDSC1; GDSC2; CTRP2 2.9456 26.7983 -7.6275 33.0145
Rh41 GDSC2; CTRP2 3.559 29.521 -8.4527 33.0546
G-402 GDSC2; CTRP2 4.1952 58.5689 -22.4287 40.671
BT-12 CTRP2 5.7169 8.7873 3.6996 4.4794
MES-SA GDSC2; CTRP2 6.3673 7.8909 4.5141 0.4647
BT-16 CTRP2 6.8507 14.5276 1.7109 10.6981
TE 617.T CTRP2 7.2153 33.567 -7.4506 31.3747
RKN GDSC2; CTRP2; CTRP1 7.2931 21.2574 -1.1511 15.7444
SK-LMS-1 GDSC1; GDSC2; CTRP2 7.6761 56.3431 -18.4461 36.0096
TTC-709 CTRP2 7.7406 73.9717 -27.199 41.661
RD GDSC2; CTRP2 8.0149 32.2432 -6.1657 24.3734
Rh18 CTRP2 9.0442 31.0067 -4.7728 24.8923
HT-1080 GDSC2; CTRP2; CTRP1 9.0916 19.8576 0.8132 8.6387
Tm87-16 CTRP2 10.2252 49.9341 -13.2426 33.3498
SK-UT-1 GDSC1; GDSC2; CTRP2 11.2177 39.3648 -7.2825 22.6262
Hs 729.T CTRP2 12.1131 28.3637 -1.3827 13.6026
GCT GDSC2; CTRP2 12.8156 36.2449 -4.6512 16.856
SW982 GDSC1; GDSC2; CTRP2 13.0432 45.9877 -9.2045 23.4923
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 7.1417 15.4971 1.446 11.2451
H-STS CTRP2 7.9101 17.4149 1.0538 11.5243
SYO-1 CTRP2 12.8175 38.1444 -5.5611 21.6569
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.8842 42.8351 -11.5396 34.549
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2; CTRP1 -1.4963 5.8685 -2.2989 34.0163
NCI-H2452 GDSC2; CTRP2 0.9256 36.2141 -14.0932 40.7602
MPP 89 GDSC1; GDSC2; CTRP2 4.9414 12.0557 1.4525 11.0905
NCI-H28 GDSC2; CTRP2; CTRP1 8.5801 24.0133 -1.5528 15.192
ACC-MESO-1 CTRP2 10.8299 30.5111 -3.2494 19.5657
NCI-H2052 GDSC2; CTRP2; CTRP1 11.1939 42.3231 -8.6268 24.7463
JL-1 CTRP2 11.6905 29.3121 -2.0983 15.883
IST-Mes1 GDSC1; GDSC2; CTRP2 13.3477 33.4553 -2.9811 13.1892
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2; CTRP2 -2.7157 22.342 -10.6931 44.7472
PC-3 GDSC2 0.2545 13.4985 -10.8599 15.0975
PaCa-3 CTRP2; CTRP1 0.3133 19.6942 -6.4307 42.8561
22Rv1 GDSC2; CTRP2 0.5886 34.2688 -13.4291 40.871
NCI-H660 GDSC2; CTRP2 2.4581 7.8134 1.1761 18.039
VCaP GDSC1; GDSC2; CTRP2 7.7052 16.5809 1.3148 8.0967
DU145 GDSC2; CTRP2 9.8127 37.1563 -7.2316 23.9743
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 0.4661 2.1667 -3.8613 0.047
YD-15 CTRP2 9.4649 23.9653 -2.6651 13.6709
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -8.2494 4.3658 -11.7747 49.7742
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC2; CTRP2 -7.5541 15.4604 -12.4817 55.0065
GCIY GDSC1; GDSC2 -3.8018 3.1504 -6.9662 19.2666
RF-48 GDSC1; GDSC2 -3.3148 5.0313 -7.4926 20.2075
ECC10 GDSC2; CTRP2 -1.4313 8.3002 -3.118 34.9681
SK-GT-2 GDSC2 -1.1381 9.7716 -9.9981 14.2597
NCC-StC-K140 CTRP2 -0.0671 26.4538 -10.1704 45.2104
SNU-1 GDSC1; GDSC2; CTRP2 -0.0564 15.5692 -4.9004 34.7205
TGBC11TKB GDSC2 -0.0439 15.1224 -11.813 18.5553
MKN28 GDSC2 -0.0114 3.2717 -6.6967 0.3414
SCH GDSC2 0.1395 21.5522 -13.0053 29.9625
TMK-1 GDSC2 0.2567 13.3813 -8.9118 20.3348
RERF-GC-1B GDSC2 0.3584 4.6934 -7.058 0.9171
HSC-39 GDSC1; GDSC2 0.4058 2.0608 -3.8467 0.0433
SNU-216 CTRP2 1.09 67.7239 -29.6488 47.0911
SNU-16 GDSC1; CTRP2 1.66 9.3597 -0.3238 27.0655
SNU-5 GDSC1; GDSC2; CTRP2 2.3297 15.4124 -2.5455 25.9144
NCI-N87 GDSC1; GDSC2; CTRP2 2.7979 25.9819 -7.3508 32.912
OCUM-1 GDSC2; CTRP2 3.1952 12.0397 -0.0928 18.3142
GSS CTRP2 4.5977 29.345 -7.4802 35.3172
MKN1 GDSC2; CTRP2 4.6546 5.2174 4.5618 2.1321
AGS GDSC2; CTRP2; CTRP1 4.7914 9.7312 2.5914 8.5349
KATO III GDSC2; CTRP2 5.3711 6.9941 4.3266 1.7749
MKN74 CTRP2; CTRP1 5.7609 19.8015 -1.6323 23.9617
GSU CTRP2 5.9194 6.4783 4.864 0.0535
MKN45 GDSC2; CTRP2 6.5038 7.2967 4.7911 0.0304
23132/87 GDSC2; CTRP2 7.0223 8.4729 4.5705 0.1559
SNU-719 CTRP2 7.3432 19.0219 -1.7014 13.5175
Fu97 GDSC2; CTRP1 7.4023 19.4994 -0.2005 13.1836
KE-39 CTRP2 8.1024 25.9078 -2.9614 22.6745
IM95 GDSC2; CTRP2 8.1952 17.1594 1.3687 7.4443
NUGC-4 GDSC2; CTRP2; CTRP1 8.2955 32.923 -6.167 24.3853
Hs 746.T GDSC2; CTRP2 8.517 25.6357 -2.5201 17.0022
NUGC-3 GDSC2; CTRP2 8.5235 50.4726 -14.8394 33.0336
HuG1-N CTRP2 8.7642 33.9261 -6.4257 27.9118
SNU-601 CTRP2 9.1278 34.9468 -6.6551 27.7639
SNU-620 CTRP2 9.2002 22.1065 -0.3211 14.2108
SNU-668 CTRP2 9.5598 40.6791 -10.6512 28.8194
MKN7 GDSC2; CTRP2; CTRP1 11.5052 34.846 -4.7464 19.9627
ECC12 GDSC2; CTRP2 12.3198 30.7611 -2.374 13.9471
SH-10-TC CTRP2; CTRP1 12.4154 33.9297 -3.6802 19.0058
LMSU CTRP2 13.4625 37.3953 -4.7679 19.557
SNG-M GDSC2; CTRP2; CTRP1 4.8998 6.0874 4.4917 2.6483
SNU-1077 CTRP2 7.9391 9.7621 4.4567 0.1663
SNU-685 CTRP2 14.9125 41.0852 -5.5649 19.4899
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 -2.1078 18.5163 -14.9185 29.1508
K5 GDSC1; GDSC2 -0.709 13.9462 -9.8869 22.5052
ASH-3 GDSC2 -0.3125 8.1349 -8.7613 7.8904
WRO GDSC2 -0.2552 8.8497 -9.0453 9.0078
KMH-2 GDSC2 0.1049 10.2483 -7.5075 15.558
HTC-C3 GDSC2 0.162 5.6517 -7.4951 2.2963
CAL-62 GDSC2 0.3274 6.7713 -7.8621 3.4828
8305C GDSC2; CTRP2 6.2851 30.0192 -6.4247 26.8618
TT GDSC2; CTRP2 7.0163 8.5835 4.5278 0.2111
BHT-101 GDSC2; CTRP2 7.4816 8.8946 4.5914 0.0696
ML-1 [Human leukemia] GDSC2; CTRP2 7.8089 30.4113 -5.4152 25.0707
8505C GDSC2; CTRP2 9.4748 23.2849 -0.7 11.6632
CGTH-W-1 GDSC1; GDSC2; CTRP2 9.6409 32.2691 -4.9531 20.5464
TT2609-C02 GDSC2; CTRP2 9.925 35.7216 -6.4411 22.6883
B-CPAP GDSC2; CTRP2 10.4978 24.1678 -0.4442 10.0325
SW579 CTRP2 12.0735 55.4198 -14.5521 32.5558
FTC-133 CTRP2 13.4495 38.2781 -5.1975 20.3461
FTC-238 CTRP2 13.7142 48.2524 -9.8299 26.6715
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OSC-19 GDSC2 -2.1267 5.8915 -6.9745 18.1945
PCI-04B GDSC2 -1.6939 19.618 -13.465 33.9069
JHU-011 GDSC2 -1.5521 22.2013 -14.6402 35.1124
Ca9-22 GDSC2 -1.2918 18.1611 -14.143 26.3179
HO-1-u-1 GDSC2 -0.6645 26.1868 -17.624 30.9036
KON GDSC2 -0.6076 24.1438 -14.8635 33.7886
KOSC-2 GDSC2 -0.5392 8.6989 -7.2011 15.5653
DOK GDSC2 -0.4403 9.2418 -9.3275 10.4471
OSC-20 GDSC2 -0.3791 7.4323 -8.491 6.8224
PCI-15A GDSC2 -0.1524 15.7769 -10.3759 25.2401
PCI-06A GDSC2 -0.1336 4.204 -4.8775 3.5682
UPCI-SCC-090 GDSC2 -0.0785 2.4789 -6.4555 0.0975
BB49-HNC GDSC1; GDSC2 -0.0511 16.3318 -10.574 23.1011
SKN-3 GDSC2 -0.0158 2.5394 -6.4545 0.0919
NCI-H3118 GDSC2 0.027 7.519 -8.316 5.5918
BICR 10 GDSC2 0.0699 8.7704 -8.8307 7.6761
JHU-029 GDSC2 0.0947 16.2399 -10.4221 24.8819
SAS GDSC2 0.1008 12.1704 -10.3406 13.5306
BICR 78 GDSC2 0.1068 4.1114 -6.9456 0.7602
HO-1-N-1 GDSC2 0.1174 2.7032 -6.464 0.088
BB30-HNC GDSC1; GDSC2 0.2654 27.7552 -15.9815 33.7068
JHU-022 GDSC2 0.4586 3.9772 -6.7715 0.3511
SAT [Human HNSCC] GDSC2 0.4833 24.5244 -15.9768 26.9046
PCI-30 GDSC2 0.6076 3.3774 -6.522 0.0884
SCC-15 GDSC1; GDSC2 0.6284 3.1656 -4.141 0.3022
SCC-25 GDSC2; CTRP2 1.0196 17.5801 -4.8282 35.1847
LB771-HNC GDSC1; GDSC2 1.7274 19.3932 -10.7964 20.8158
CAL-33 GDSC2; CTRP2 1.7913 20.7569 -5.6641 32.3556
HSC-2 GDSC2; CTRP2; CTRP1 2.9256 4.5438 2.8622 11.1259
FaDu GDSC2; CTRP2 4.3846 5.3445 4.2248 3.6167
SCC-4 GDSC2; CTRP2 4.4578 14.5098 -0.1856 16.5452
YD-10B CTRP2 4.7228 32.45 -10.2781 34.647
BHY GDSC2; CTRP2 5.2367 22.2737 -3.4105 25.0856
PE/CA-PJ15 GDSC2; CTRP2 5.5735 35.532 -9.7607 33.4842
CAL-27 GDSC2; CTRP2 7.1883 8.9664 4.4554 0.2677
BICR 16 CTRP2 7.8118 46.992 -13.6701 36.1711
Detroit 562 GDSC2; CTRP2 7.843 32.8947 -6.6227 25.2625
BICR 22 GDSC2; CTRP2 8.2324 29.3091 -4.5444 21.3981
BICR 18 CTRP2 8.6469 36.1137 -7.5995 29.6447
HSC-4 GDSC2; CTRP2 9.1555 30.2376 -4.3118 19.9169
YD-8 CTRP2 9.5277 42.273 -9.9783 31.2459
SNU-1066 CTRP2 9.8212 32.693 -5.0291 24.3082
SNU-899 CTRP2 9.8575 23.9456 -2.4143 12.447
BICR 31 GDSC2; CTRP2 10.1115 29.9039 -3.4574 18.6295
SNU-46 CTRP2 10.3461 29.7929 -3.9977 19.1973
SNU-1214 CTRP2 10.4098 25.2997 -1.0366 14.6909
PE/CA-PJ34 (clone C12) CTRP2 10.9784 29.3868 -2.6071 17.9475
PE/CA-PJ41 (clone D2) CTRP2 11.9892 43.189 -8.5954 26.967
SCC-9 GDSC2; CTRP2; CTRP1 13.1254 33.5121 -3.0137 13.8483
SNU-1041 CTRP2 13.2181 38.6262 -5.5198 21.1529
PE/CA-PJ49 CTRP2 13.2602 34.7065 -3.6258 17.5439
BICR 56 CTRP2 13.5102 51.0579 -11.3452 28.4794
BICR 6 CTRP2 13.7815 53.6394 -12.4122 29.2438
HSC-3 GDSC2; CTRP2 13.9122 33.1916 -2.5047 11.7434
SNU-1076 CTRP2 15.8891 44.8041 -6.6868 20.3834
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW780 GDSC2 -0.457 6.1214 -7.9728 4.7026
U-BLC1 CTRP2 1.3116 71.5297 -31.3579 47.0658
RT-4 GDSC2; CTRP2; CTRP1 1.3398 29.0328 -10.0631 37.9475
253J CTRP2 2.9393 16.0945 -2.3201 30.9012
5637 GDSC2; CTRP2; CTRP1 3.9596 19.1046 -2.8053 24.2052
UM-UC-1 CTRP2 4.8635 12.8604 0.9846 17.0082
BFTC-905 GDSC2; CTRP2 5.3641 6.8795 4.3777 1.6297
TCCSUP GDSC2; CTRP2 5.5695 29.0318 -6.5146 27.9156
CAL-29 GDSC2; CTRP2 6.2356 8.979 3.959 1.9698
639V GDSC2; CTRP2 6.4972 7.4856 4.7238 0.0845
KU-19-19 GDSC2; CTRP2 6.6927 7.6914 4.7234 0.0578
BC-3C CTRP2 7.2589 22.6996 -2.0124 21.7821
UM-UC-3 GDSC2; CTRP2; CTRP1 8.0322 28.9252 -4.386 21.7302
SW1710 GDSC2; CTRP2 8.405 22.9699 -1.2954 14.2855
JMSU-1 CTRP2 8.579 20.1713 0.1855 14.2319
HT-1197 GDSC2; CTRP2 8.716 29.9111 -4.4775 20.7176
HT-1376 GDSC2; CTRP2; CTRP1 8.7348 23.9516 -1.4108 14.6824
KMBC-2 CTRP2; CTRP1 10.7554 31.1055 -3.4584 20.5364
647V GDSC2; CTRP2 10.9462 36.8815 -6.2637 21.3658
VM-CUB-1 CTRP2 11.1664 36.5081 -5.9233 24.1343
RT-112 GDSC2; CTRP2 12.4304 36.097 -4.8411 17.5503
SCaBER CTRP2 15.2698 49.3554 -9.277 24.5423
T24 GDSC2; CTRP2 16.1835 39.7715 -4.1477 14.1152
J82 GDSC2; CTRP2 17.2722 46.3953 -6.5457 16.3218
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC2 -5.8986 12.6788 -15.0183 36.728
PA-1 GDSC2 -4.9104 17.0615 -16.3912 36.3464
NT2-D1 GDSC1; GDSC2 -1.9595 18.5805 -13.1595 31.5071
KGN GDSC1; GDSC2 -1.47 13.8338 -10.4095 25.2601
JAR GDSC1; GDSC2 -1.253 5.6491 -6.2223 12.4722
HEY GDSC2 -0.7529 6.9441 -8.4807 7.2724
ACC-OV7 GDSC2 -0.6282 15.8139 -10.7482 27.048
JHOS-3 GDSC2 -0.6107 5.3555 -5.6631 8.2922
Ca Ski GDSC2 -0.5104 20.8504 -14.8947 26.5009
OVCA433 GDSC2 -0.4559 16.4783 -10.9468 27.1545
DSH1 GDSC1; GDSC2 -0.451 10.0034 -7.7702 15.3261
C-33 A GDSC2 -0.398 4.8457 -7.427 2.4802
SKG-IIIa GDSC2 -0.3881 18.4113 -13.6229 23.7371
OV17R GDSC2 -0.3261 9.6135 -7.4952 16.3632
UWB1.289 GDSC2 -0.3215 12.7597 -9.02 21.8217
SKN GDSC2 -0.3179 7.6974 -8.5731 7.0952
SiHa GDSC2 -0.1551 14.1294 -11.4158 17.5378
PWR-1E GDSC2 -0.1419 13.7292 -11.2187 16.8958
DoTc2 4510 GDSC2 -0.1012 14.4524 -11.5333 17.8124
HT-3 GDSC2 -0.0317 7.067 -8.1558 4.9967
OVCA420 GDSC2 -0.0176 12.8684 -10.7369 15.1046
NCC-IT GDSC1; GDSC2 -0.0058 8.3354 -6.673 10.2764
CAL-39 GDSC2 0.0374 35.8913 -21.8876 34.3295
MS751 GDSC2 0.0505 2.7713 -6.5084 0.1244
HEC-1 GDSC2 0.0738 3.0267 -6.5849 0.1901
C-4-I GDSC2 0.0769 7.1953 -8.1553 4.8777
ME-180 GDSC2 0.0796 14.9031 -11.6287 17.8123
LB831-BLC GDSC1; GDSC2 0.1034 2.1618 -3.9833 0.1944
SW962 GDSC1; GDSC2 0.2396 14.7048 -9.5671 22.3452
PEO1 GDSC2 0.2636 2.5444 -6.3651 0.0351
NEC8 GDSC1; GDSC2 0.2664 6.0158 -5.4483 4.767
SiSo GDSC2 0.2677 3.5401 -6.6902 0.2793
SW954 GDSC1; GDSC2 0.4151 13.8073 -9.0075 20.335
OVMIU GDSC2 0.4773 3.9723 -6.7633 0.3361
JEG-3 GDSC2 0.4831 3.3275 -4.253 0.6693
SW756 GDSC2 0.5705 2.8918 -6.3776 0.0295
TC-YIK GDSC1; GDSC2 1.3376 13.593 -8.2828 14.2295
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.4173 16.6897 -9.7067 20.6055
HeLa GDSC2; CTRP2 6.8364 7.7253 4.7616 0.0232
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
3 BDDCS applied to over 900 drugs
4 Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose