Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM95FR3)

Drug Name
Tarextumab Drug Info
Indication
Disease Entry ICD 11 Status REF
Pancreatic cancer 2C10 Phase 2 [1]
Small-cell lung cancer 2C25.Y Phase 2 [2]
Cross-matching ID
TTD Drug ID
DM95FR3

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Notch-2 receptor (NOTCH2) TT82FVD NOTC2_HUMAN Modulator [3]
Notch-3 receptor (NOTCH3) TTVX7IA NOTC3_HUMAN Modulator [3]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8453).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Company report (OncoMed Pharmaceuticals)