Details of the Drug

General Information of Drug (ID: DM95FR3)

Drug Name
Tarextumab
Indication
Disease Entry ICD 11 Status REF
Pancreatic cancer 2C10 Phase 2 [1]
Small-cell lung cancer 2C25.Y Phase 2 [2]
Drug Type
Monoclonal antibody
Cross-matching ID
UNII
333YMY788E
DrugBank ID
DB12104
TTD ID
D01QLP
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Notch-2 receptor (NOTCH2) TT82FVD NOTC2_HUMAN Modulator [3]
Notch-3 receptor (NOTCH3) TTVX7IA NOTC3_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8453).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Company report (OncoMed Pharmaceuticals)