Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM95IPS)

Drug Name
Tivanisiran Drug Info
Indication
Disease Entry ICD 11 Status REF
Dry eye disease 9E1Z Phase 3 [1]
Cross-matching ID
TTD Drug ID
DM95IPS

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TRPV1 messenger RNA (TRPV1 mRNA) TT50OG3 TRPV1_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04819269) Tivanisiran for Dry Eye in Subjects With Sjogren's Syndrome. U.S. National Institutes of Health.
2 Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.