Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAX632)

Drug Name

HDV-interferon Drug Info

Synonyms

HDV-interferon (sc, HCV infection); HDV-IFN (sc, HCV infection), Hepasome Pharmaceuticals; HDV-interferon (sc, HCV infection), Hepasome Pharmaceuticals

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis C virus infection	1E51.1	Phase 2	[1]

Cross-matching ID

TTD Drug ID: DMAX632

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting Interferon receptor (IFNR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Z-100	DM1H75D	Human immunodeficiency virus infection	1C62	Phase 1	[3]
Bropirimine	DMMT1YQ	Virus infection	1A24-1D9Z	Discontinued in Phase 3	[4]
Omniferon	DMSKAGP	Solid tumour/cancer	2A00-2F9Z	Terminated	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interferon receptor (IFNR)	TTV2CN0	NOUNIPROTAC	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00703872) HDV-Interferon in the Treatment of Chronic Hepatitis C Nonresponders and Naive Hepatitis C Patients. U.S. National Institutes of Health.
2	Interferon in HDV infection. Antiviral Res. 1994 Jul;24(2-3):165-74.
3	Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J Gen Virol. 2004 Sep;85(Pt 9):2603-13.
4	Comparison between circulating interferon and drug levels following administration of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP) to different animal species. J Interferon Res. 1982;2(3):317-27.
5	US patent application no. 2004,0229,936, Treatment of hepatitis c virus infection with sesquiterpene lactones.