Details of the Drug-Related molecule(s) Interaction Atlas | DrugMAP

General Information of Drug (ID: DMBCG31)

Drug Name	PR-39 Drug Info
Synonyms	PR 39; PR-39; 139637-11-9; PR-39 proline-arginine-rich peptide; PR39 proline-arginine-rich peptide; DTXSID90161139; JTJJGVCUEGCBHL-IWDHFESKSA-N
Cross-matching ID	PubChem CID 16198954 CAS Number CAS 139637-11-9 TTD Drug ID DMBCG31 INTEDE Drug ID DR2683

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Dipeptidylpeptidase IV (DPP4)^{Main DME}	DEX542K	A0A4T2GYT7_STRSU	Substrate	[1] , [2]

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References

1	Dipeptidylpeptidase IV of Streptococcus suis degrades the porcine antimicrobial peptide PR-39 and neutralizes its biological properties. Microb Pathog. 2018 Sep;122:200-206.
2	Streptococcus suis infection: an emerging/reemerging challenge of bacterial infectious diseases? Virulence. 2014 May 15;5(4):477-97.