Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBEP7G)

Drug Name

Fomivirsen sodium Drug Info

Synonyms

Vitravene; Vitravene Preservative Free; DRG-0234; Vitravene (TN); DNA, d(P-thio)(G-C-G-T-T-T-G-C-T-C-T-T-C-T-T-C-T-T-G-C-G), eicosasodium salt

Indication

Disease Entry	ICD 11	Status	REF
Cytomegalovirus retinitis	9B72.00	Approved	[1]

Therapeutic Class

Antisense

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Cytomegalovirus IE2 region messenger RNA (CMV IE2 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 12659	DMZGKHO	Discovery agent	N.A.	Investigative	[3]
ISIS 2921	DMDZAKS	Discovery agent	N.A.	Investigative	[4]
ISIS 3246	DM56EZC	Discovery agent	N.A.	Investigative	[4]
ISIS 2919	DMVMF5X	Discovery agent	N.A.	Investigative	[4]
ISIS 2920	DMJFLK0	Discovery agent	N.A.	Investigative	[4]
ISIS 2918	DMJTHXY	Discovery agent	N.A.	Investigative	[4]
ISIS 12660	DMNOPWB	Discovery agent	N.A.	Investigative	[3]
ISIS 3300	DM2TIO1	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytomegalovirus IE2 region messenger RNA (CMV IE2 mRNA)	TT4SCBE	VIE2_HCMVA	Modulator	[2]

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References

1	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	US patent application no. 5,767,102, Antisense composition and method for treatment of CMV infection.
4	US patent application no. 5,442,049, Oligonucleotides for modulating the effects of cytomegalovirus infections.