Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCP2BJ)

Drug Name
MLS-101 Drug Info
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Phase 2 [1]
Cross-matching ID
PubChem CID
169490736
TTD Drug ID
DMCP2BJ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Aldosterone synthase (CYP11B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Baxdrostat DM7A4QE Hypertension BA00-BA04 Phase 2 [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aldosterone synthase (CYP11B2) TT9MNE2 C11B2_HUMAN Inhibitor [1]

References

1 ClinicalTrials.gov (NCT05001945) A Randomized, Double-blind, Placebo-controlled, Dose-ranging, Multicenter Phase 2 Study to Evaluate the Safety, Efficacy, and Tolerability of MLS-101 in Subjects With Uncontrolled Hypertension. U.S.National Institutes of Health.
2 Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension. N Engl J Med. 2023 Feb 2;388(5):395-405.