Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDKE4N)

Drug Name

Secretin Drug Info

Synonyms

SECREFLO; SecreFlow; Secrepan; Secretina; Secretine; Secretinum; Secretolin; Vitrum; Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level; Human secretin; RG 1068; L-Valinamide; SECRETIN-FERRING; Secretin (human); Secretin (porcine); Secretin-Kabi; Secretina [INN-Spanish]; Secretine [INN-French]; Secretinum [INN-Latin]; Secretin [INN:BAN:DCF:JAN]

Indication

Disease Entry	ICD 11	Status	REF
Gastrinoma	2C10.1	Approved	[1]
Pancreatic exocrine dysfunction	DC3Z	Approved	[1]

Therapeutic Class

Diagnostic Agents

Cross-matching ID

PubChem CID: 16129665
CAS Number: CAS 1393-25-5
TTD Drug ID: DMDKE4N
VARIDT Drug ID: DR01202

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Secretin receptor (SCT)	TTOBVIN	SECR_HUMAN	Binder	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3644).
2	False-positive secretin stimulation test for gastrinoma associated with the use of proton pump inhibitor therapy. Clin Gastroenterol Hepatol. 2009 May;7(5):600-2.