Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DME69PI)

Drug Name

SEA-0400 Drug Info

Synonyms

SEA0400; 223104-29-8; SEA-0400; SEA 0400; 2-(4-((2,5-DIFLUOROBENZYL)OXY)PHENOXY)-5-ETHOXYANILINE; 2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxybenzenamine; 2-[4-[(2,5-Difluorobenzyl)oxy]phenoxy]-5-ethoxyaniline; 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline; 2-(4-(2,5-difluorobenzyloxy)phenoxy)-5-ethoxyaniline; 2-[4-(2,5-Difluorobenzyloxy)phenoxy]-5-ethoxyaniline; 2-{4-[(2,5-Difluorobenzyl)oxy]phenoxy}-5-ethoxyaniline; 2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline

Indication

Disease Entry	ICD 11	Status	REF
Cerebrovascular ischaemia	8B1Z	Investigative	[1]

Cross-matching ID

PubChem CID: 644100
CAS Number: CAS 223104-29-8
TTD Drug ID: DME69PI

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Sodium/calcium exchanger (SLC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CALDARET HYDRATE	DMDV8MK	Cardiovascular disease	BA00-BE2Z	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sodium/calcium exchanger (SLC)	TT619TC	NOUNIPROTAC	Inhibitor	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4617).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4617).
3	Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. J Pharmacol Sci. 2007 Feb;103(2):222-33.