Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DME94KO)

Drug Name
Trecetilide fumarate Drug Info
Synonyms PNU-108342E; Trecetilide fumarate < Prop INNM; (-)-N-[4-[4-[N-Ethyl-N-(6-fluoro-6-methylheptyl)amino]-1(S)-hydroxybutyl]phenyl]methanesulfonamide fumarate (2:1)
Indication
Disease Entry ICD 11 Status REF
Cardiac arrhythmias BC9Z Investigative [1]
Cross-matching ID
PubChem CID
6441132
CAS Number
CAS 191349-60-7
TTD Drug ID
DME94KO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Potassium channel unspecific (KC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [2]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [2]
Dronedarone DMA8FS5 Angina pectoris BA40 Approved [3]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [2]
Amifampridine DMK08L3 LambertEaton myasthenic syndrome 8C62 Approved [4]
Minoxidil DMA2Z4F Alopecia ED70 Approved [2]
Pinacidil DMRADYL High blood pressure BA00 Approved [2]
Dalfampridine DMM0PDO Multiple sclerosis 8A40 Approved [5]
Ibutilide DMKXY2R Atrial fibrillation BC81.3 Approved [2]
Diazoxide DML1538 Congenital hyperinsulinism 5A4Y Approved [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Potassium channel unspecific (KC) TT1VOHK NOUNIPROTAC Blocker [1]

References

1 IKr channel blockers: novel antiarrhythmic agents. Curr Med Chem Cardiovasc Hematol Agents. 2003 Oct;1(3):203-23.
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
4 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
5 Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.