Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMER9YA)

Drug Name

Galsulfase Drug Info

Synonyms

Aryplase; Aryplase (TN); Galsulfase (genetical recombination); Galsulfase (USAN/INN); Galsulfase (genetical recombination) (JAN)

Indication

Disease Entry	ICD 11	Status	REF
Mucopolysaccharidosis	5C56.3	Approved	[1]

Therapeutic Class

Enzyme Replacement Agents

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
N-acetylgalactosamine-4-sulfatase (G4S)	TTESQTG	ARSB_HUMAN	Modulator	[2]

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References

1	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2	Enzyme replacement therapy for mucopolysaccharidosis VI: long-term cardiac effects of galsulfase (Naglazyme ) therapy. J Inherit Metab Dis. 2013 Mar;36(2):385-94.