Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFJES5)

Drug Name
ISIS 100750 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMFJES5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting ADAM10 messenger RNA (ADAM10 mRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ISIS 100748 DMFW5VK Discovery agent N.A. Investigative [1]
ISIS 100742 DMIB6JL Discovery agent N.A. Investigative [1]
ISIS 100743 DMI7PGZ Discovery agent N.A. Investigative [1]
ISIS 100749 DMSMJ37 Discovery agent N.A. Investigative [1]
PMID18068976C25 DMTZQUJ Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
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Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ADAM10 messenger RNA (ADAM10 mRNA) TTVXEGU ADA10_HUMAN Not Available [1]

References

1 US patent application no. 6,228,648, Antisense modulation of ADAM10 expression.
2 Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations. Bioorg Med Chem Lett. 2008 Jan 15;18(2):560-4.