Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIG5W8)

Drug Name
MCPP Drug Info
Synonyms 1-(3-Chlorophenyl)piperazine
Indication
Disease Entry ICD 11 Status REF
Mood disorder 6A60-6E23 Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
7153
ChEBI ID
CHEBI:75704
CAS Number
CAS 93-65-2
TTD Drug ID
DMIG5W8
INTEDE Drug ID
DR1789

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting 5-HT 2C receptor (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [5]
Lorcaserin DMG6OYJ Obesity 5B81 Approved [6]
Tramadol DMRQD04 Osteoarthritis FA00-FA05 Approved [7]
Mirtazapine DML53ZJ Depression 6A70-6A7Z Approved [8]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [9]
Methysergide DM1EF73 Migraine 8A80 Approved [10]
Eltoprazine DMW6C81 Attention deficit hyperactivity disorder 6A05.Z Phase 3 [11]
M100907 DM7ZFBA Sleep-wake disorder 7A00-7B2Z Phase 3 [12]
SR46349B DM1ODMR Primary insomnia 7A00 Phase 3 [13]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [14]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [16]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [17]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [19]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [20]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [21]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [22]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [23]
Propranolol DM79NTF Angina pectoris BA40 Approved [24]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [25]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [26]
Fructose DM43AN2 Vomiting MD90 Approved [27]
Ketoprofen DMRKXPT Bursitis Approved [27]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [29]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [30]
Gefitinib DM15F0X Colon adenocarcinoma Approved [31]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [32]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [33]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [34]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [35]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [36]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [37]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [39]
Quercetin DM3NC4M Obesity 5B81 Approved [40]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [42]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [43]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Agonist [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6) Main DME DECB0K3 CP2D6_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Gene/Protein Processing [4]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Gene/Protein Processing [4]

References

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