Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIOUFK)

Drug Name

Emfilermin Drug Info

Synonyms

AM-424; Leukemia inhibitory factor, AMRAD; RhLIF, AMRAD; RhLIF, Serono; Recombinant LIF protein, AMRAD/Serono; R-LIF, AMRAD/Serono

Indication

Disease Entry	ICD 11	Status	REF
Infertility	GB04	Phase 1/2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukemia inhibitory factor receptor (LIFR)	TTID542	LIFR_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT00504530) r-hLIF for Improving Embryo Implantation in IVF. U.S. National Institutes of Health.
2	Population pharmacokinetic modelling of Emfilermin (recombinant human leukaemia inhibitory factor, r-hLIF) in healthy postmenopausal women and in infertile patients undergoing in vitro fertilization and embryo transfer. Br J Clin Pharmacol. 2004 May; 57(5): 576-585.