Details of the Drug

General Information of Drug (ID: DMIOUFK)

Drug Name
Emfilermin
Synonyms AM-424; Leukemia inhibitory factor, AMRAD; RhLIF, AMRAD; RhLIF, Serono; Recombinant LIF protein, AMRAD/Serono; R-LIF, AMRAD/Serono
Indication
Disease Entry ICD 11 Status REF
Infertility GB04 Phase 1/2 [1]
Cross-matching ID
UNII
N70J8Y06YN
DrugBank ID
DB06562
TTD ID
D0L1FN

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukemia inhibitory factor receptor (LIFR) TTID542 LIFR_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00504530) r-hLIF for Improving Embryo Implantation in IVF. U.S. National Institutes of Health.
2 Population pharmacokinetic modelling of Emfilermin (recombinant human leukaemia inhibitory factor, r-hLIF) in healthy postmenopausal women and in infertile patients undergoing in vitro fertilization and embryo transfer. Br J Clin Pharmacol. 2004 May; 57(5): 576-585.