Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKY1L4)

Drug Name
Glucose-6-Phosphate Drug Info
Synonyms
Robison ester; Glucose 6-phosphate; 6-O-phosphono-D-glucopyranose; D-glucopyranose 6-phosphate; D-glucopyranose, 6-(dihydrogen phosphate); Glucose 6-(dihydrogen phosphate); 299-31-0; {[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid; D-glucose-6P; Glc6P; D-glucose-6-P; a-D-glucose 6- phosphate; AC1L1LI0; SCHEMBL48379; CHEBI:4170; GTPL4647; AC1Q28E3; D-Glucopyranose 6-phosphoric acid
Cross-matching ID
PubChem CID
5958
ChEBI ID
CHEBI:4170
CAS Number
CAS 299-31-0
TTD Drug ID
DMKY1L4
VARIDT Drug ID
DR00098

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
Drug Status:
Investigative Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Glucosamine-6-phosphate synthase (Bact glmS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetate Ion DMD08RH Discovery agent N.A. Investigative [1]
2-Methyl-2,4-Pentanediol DMD45CU Discovery agent N.A. Investigative [1]
2-(N-Morpholino)-Ethanesulfonic Acid DMZVHSB Discovery agent N.A. Investigative [1]
Alpha-D-Glucose-6-Phosphate DMR0EVN Discovery agent N.A. Investigative [1]
Glutamine Hydroxamate DMT7K0U Discovery agent N.A. Investigative [1]
2-Deoxy-2-Amino Glucitol-6-Phosphate DMBMK4T Discovery agent N.A. Investigative [1]
Glucosamine 6-Phosphate DMY590Q Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Transported By Glycerol-3-phosphate permease (SLC37A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phosphate DMUXQG7 Constipation DD91.1 Approved [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Glucosamine-6-phosphate synthase (Bact glmS) TTC67I0 GLMS_ECOLI Inhibitor [1]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Glucose-6-phosphate translocase (SLC37A4) DTLHZFU G6PT1_HUMAN Substrate [2]
Glycerol-3-phosphate permease (SLC37A1) DTH9SQJ G6PT2_HUMAN Substrate [3]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 A novel mutation (A148V) in the glucose 6-phosphate translocase (SLC37A4) gene in a Korean patient with glycogen storage disease type 1b. J Korean Med Sci. 2005 Jun;20(3):499-501.
3 SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters. PLoS One. 2011;6(9):e23157.