Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMQ6VT)

Drug Name

Leronlimab Drug Info

Synonyms

PRO 140

Indication

Disease Entry	ICD 11	Status	REF
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN C-C chemokine receptor 5 (CCR5)	TTH91NV	CCR5_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04343651) Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19
2	Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19