Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMN23KT)

Drug Name

isoferulic acid Drug Info

Synonyms

Isoferulic acid; 3-Hydroxy-4-methoxycinnamic acid; 537-73-5; Hesperetic acid; 25522-33-2; 3-(3-Hydroxy-4-methoxyphenyl)acrylic acid; (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid; (E)-3-(3-hydroxy-4-methoxyphenyl)acrylic acid; Isoferulate; 2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-; 3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid; 3-hydroxy-4-methoxy-cinnamic acid; CHEMBL233295; CHEBI:27794; QURCVMIEKCOAJU-HWKANZROSA-N; AK-88788; UNII-XSQ2K2G7MC; Cinnamic acid, 3-hydroxy-4-methoxy-; Q-100609

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 736186
ChEBI ID: CHEBI:27794
CAS Number: CAS 25522-33-2
TTD Drug ID: DMN23KT

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Phosphomevalonate kinase (PMVK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(R)-5-diphosphomevalonate	DMOESL1	Discovery agent	N.A.	Investigative	[3]
cinnamic acid	DM340FH	Discovery agent	N.A.	Investigative	[2]
3-hydroxy-3-methyl-6-phosphohexanoic acid	DM3YO72	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphomevalonate kinase (PMVK)	TTXMI0C	PMVK_HUMAN	Inhibitor	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7980).
2	Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds. Biochem J. 1979 Jul 1;181(1):143-51.
3	Functional evaluation of conserved basic residues in human phosphomevalonate kinase. Biochemistry. 2007 Oct 23;46(42):11780-8.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 641).