Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMN3ZOD)

Drug Name

RS-PPCC Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting HUMAN opioid receptor sigma 1 (OPRS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Haloperidol	DM96SE0	Delirium		Approved	[2]
PB28	DMMNQ1B	Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[2]
E-52862	DMLZU09	Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[2]
PD-144418	DMJKH28	Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN opioid receptor sigma 1 (OPRS1)	TTTPE1L	SGMR1_HUMAN	Agonist	[2]

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References

1	Novel sigma receptor ligands: synthesis and biological profile. J Med Chem. 2007 Mar 8;50(5):951-61.
2	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing