General Information of Drug (ID: DMNMXKC)

Drug Name
ISIS 147483 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMNMXKC

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mipomersen DMGSRN1 Familial hypercholesterolemia 5C80.00 Approved [2]
TKM-ApoB DM2M47Y Hypercholesterolaemia 5C80.0 Phase 4 [3]
ISIS 147788 DM1Z5W8 Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
APOB messenger RNA (APOB mRNA) TTN1IE2 APOB_HUMAN Not Available [1]

References

1 US patent application no. 7,407,943, Antisense modulation of apolipoprotein B expression.
2 Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
3 Current Progress of siRNA/shRNA Therapeutics in Clinical Trials. Biotechnol J. 2011 September; 6(9): 1130-1146.