Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNXR17)

Drug Name

HMR1883 Drug Info

Synonyms

Clamikalant; Clamikalant [INN]; 158751-64-5; UNII-94301K998R; CHEMBL12531; HMR-1883; 94301K998R; 1-((5-(2-(5-Chloro-o-anisamido)ethyl)-2-methoxyphenyl)sulfonyl)-3-methyl-2-thiourea; HMR1883; AC1MI3H0; SCHEMBL726268; DTXSID30166522; VXTKXGKPBOLHRY-UHFFFAOYSA-N; ZINC599915; BDBM50099573; AKOS027339538; API0011065; NCGC00386636-01; AS-44931; LS-26123; SR-01000945051; SR-01000945051-1; 5-chloro-2-methoxy-N-[2-[4-methoxy-3-(methylcarbamothioylsulfamoyl)phenyl]ethyl]benzamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3037766
CAS Number: CAS 158751-64-5
TTD Drug ID: DMNXR17
VARIDT Drug ID: DR00829

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Potassium channel unspecific (KC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nateglinide	DMLK2QH	Diabetic complication	5A2Y	Approved	[2]
Amiodarone	DMUTEX3	Tachyarrhythmias	BC71	Approved	[2]
Dronedarone	DMA8FS5	Angina pectoris	BA40	Approved	[3]
Dofetilide	DMPN1TW	Sinus rhythm disorder	BC9Y	Approved	[2]
Amifampridine	DMK08L3	LambertEaton myasthenic syndrome	8C62	Approved	[4]
Minoxidil	DMA2Z4F	Alopecia	ED70	Approved	[2]
Pinacidil	DMRADYL	High blood pressure	BA00	Approved	[2]
Dalfampridine	DMM0PDO	Multiple sclerosis	8A40	Approved	[5]
Ibutilide	DMKXY2R	Atrial fibrillation	BC81.3	Approved	[2]
Diazoxide	DML1538	Congenital hyperinsulinism	5A4Y	Approved	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Potassium channel unspecific (KC)	TT1VOHK	NOUNIPROTAC	Modulator	[1]

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References

1	Clamikalant (Aventis). IDrugs. 2000 Nov;3(11):1353-7.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
4	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
5	Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.