Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPY09A)

Drug Name	Succinate Drug Info
Cross-matching ID	PubChem CID 160419 ChEBI ID CHEBI:30031 CAS Number CAS 56-14-4 TTD Drug ID DMPY09A VARIDT Drug ID DR01246

Molecule-Related Drug Atlas

Molecule Type:

DTP

Drug Status:

Investigative Drug(s)

Preclinical Drug(s)

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Drug(s) Transported By Sodium/dicarboxylate cotransporter 3 (SLC13A3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
alpha-ketoglutaric acid	DM5LFYN	Discovery agent	N.A.	Investigative	[1]
Dicarboxylate	DML3HEM	N. A.	N. A.	Investigative	[1]
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Drug(s) Transported By Sodium-coupled citrate transporter (SLC13A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Citrate	DM37NYK	N. A.	N. A.	Preclinical	[2]
alpha-ketoglutaric acid	DM5LFYN	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Sodium/dicarboxylate cotransporter 3 (SLC13A3)	DTKXTPW	S13A3_HUMAN	Substrate	[1]
Sodium-coupled citrate transporter (SLC13A5)	DTFPWJ9	S13A5_HUMAN	Substrate	[2]

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References

1	SLC13A3 variants cause acute reversible leukoencephalopathy and -ketoglutarate accumulation. Ann Neurol. 2019 Mar;85(3):385-395.
2	SLC13 family of Na+ coupled di- and tri-carboxylate/sulfate transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):299-312.