Details of the Drug

General Information of Drug (ID: DMPY09A)

Drug Name
Succinate
Drug Type
Small molecular drug
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 116.072
Logarithm of the Partition Coefficient (xlogp) 0.7
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C4H4O4-2
IUPAC Name
butanedioate
Canonical SMILES
C(CC(=O)[O-])C(=O)[O-]
InChIKey
KDYFGRWQOYBRFD-UHFFFAOYSA-L
Cross-matching ID
PubChem CID
160419
ChEBI ID
CHEMBL30031
CAS Number
56-14-4
VARIDT ID
DR01246
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Sodium/dicarboxylate cotransporter 3 (SLC13A3) DTKXTPW S13A3_HUMAN Substrate [1]
Sodium-coupled citrate transporter (SLC13A5) DTFPWJ9 S13A5_HUMAN Substrate [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 SLC13A3 variants cause acute reversible leukoencephalopathy and -ketoglutarate accumulation. Ann Neurol. 2019 Mar;85(3):385-395.
2 SLC13 family of Na+ coupled di- and tri-carboxylate/sulfate transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):299-312.