Details of the Drug

General Information of Drug (ID: DMPY09A)

Drug Name
Succinate
Drug Type
Small molecular drug
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 116.072
Logarithm of the Partition Coefficient (xlogp) 0.7
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C4H4O4-2
IUPAC Name
butanedioate
Canonical SMILES
C(CC(=O)[O-])C(=O)[O-]
InChIKey
KDYFGRWQOYBRFD-UHFFFAOYSA-L
Cross-matching ID
PubChem CID
160419
ChEBI ID
CHEBI:30031
CAS Number
56-14-4
VARIDT ID
DR01246

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Sodium/dicarboxylate cotransporter 3 (SLC13A3) DTKXTPW S13A3_HUMAN Substrate [1]
Sodium-coupled citrate transporter (SLC13A5) DTFPWJ9 S13A5_HUMAN Substrate [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 SLC13A3 variants cause acute reversible leukoencephalopathy and -ketoglutarate accumulation. Ann Neurol. 2019 Mar;85(3):385-395.
2 SLC13 family of Na+ coupled di- and tri-carboxylate/sulfate transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):299-312.