Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR2STB)

Drug Name

ISIS 2105 Drug Info

Synonyms

UNII-7EL4K2K27P; Afovirsen sodium; 7EL4K2K27P; ISIS 2105; Afovirsen sodium [USAN]; IP 2105; I 2105; 138330-98-0; ISIS-2105; IP-2105; I-2105; Thymidine, 2'-deoxy-P-thiocytidylyl-(5'-3')-P-thiothymidylyl-(5'-3')-2'-deoxy-P-thioguanylyl-(5'-3')-2'-deoxy-P-thiocytidylyl-(5'-3')-P-thiothymidylyl-(5'-3')-2'-deoxy-P-thiocytidylyl-(5'-3')-2'-deoxy-P-thiocytidy

Indication

Disease Entry	ICD 11	Status	REF
Human papillomavirus infection	1A9Y	Discontinued in Phase 2	[1]

Cross-matching ID

PubChem CID: 71587499
CAS Number: CAS 138330-98-0
TTD Drug ID: DMR2STB

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human papillomavirus E2 transactivator messenger RNA (HPV E2 mRNA)	TTXQPKC	VE2_HPV18	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001932)
2	US patent application no. 5,665,580, Antisense oligonucleotide inhibition of papillomavirus transformed cells.