Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSL0Y5)

Drug Name
LOR-2501 Drug Info
Synonyms GTI-2501; R1 ribonucleotide reductase mRNA antisense oligo, Lorus; Antisense oligonucleotide (cancer), Lorus; U-sense technology, Lorus
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMSL0Y5

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RRM1 messenger RNA (RRM1 mRNA) TTWP0NS RIR1_HUMAN Not Available [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011360)
2 Non-covalent complexes of folic acid and oleic acid conjugated polyethylenimine: An efficient vehicle for antisense oligonucleotide delivery. Colloids Surf B Biointerfaces. 2015 Jul 26;135:274-282.