Details of the Drug

General Information of Drug (ID: DMSL0Y5)

Drug Name
LOR-2501
Synonyms GTI-2501; R1 ribonucleotide reductase mRNA antisense oligo, Lorus; Antisense oligonucleotide (cancer), Lorus; U-sense technology, Lorus
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [1]
Drug Type
Antisense drug
Cross-matching ID
UNII
G9AU73Z0Y0
DrugBank ID
DB05406
TTD ID
D0K4OL

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RRM1 messenger RNA (RRM1 mRNA) TTWP0NS RIR1_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011360)
2 Non-covalent complexes of folic acid and oleic acid conjugated polyethylenimine: An efficient vehicle for antisense oligonucleotide delivery. Colloids Surf B Biointerfaces. 2015 Jul 26;135:274-282.