Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSWJ6D)

Drug Name

NU-206 Drug Info

Synonyms

HRSpo-1; Secreted proteins (IBD), ARCA; Secreted proteins (mucositis), ARCA; Secreted proteins (GI and bone diseases),Kyowa Hakko Kirin/ARCA; Secreted proteins (IBD), Kirin/ARCA; Secreted proteins (inflammatory bowel disease), ARCA/Kirin; Secreted proteins (mucositis), Kirin/ARCA; Human R-Spondin-1 (GI and bone diseases), ARCA; Low-density lipoprotein receptor related protein 6 (IBD), Kirin/ARCA

Indication

Disease Entry	ICD 11	Status	REF
Gastrointestinal disease	DE2Z	Phase 1	[1]

Cross-matching ID

TTD Drug ID: DMSWJ6D

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Roof plate-specific spondin-1 (RSPO1)	TTI9HL4	RSPO1_HUMAN	Modulator	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3697).
2	R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation.BMC Dev Biol.2008 Apr 2;8:36.