Details of the Drug

General Information of Drug (ID: DMSWJ6D)

Drug Name

NU-206

Synonyms

HRSpo-1; Secreted proteins (IBD), ARCA; Secreted proteins (mucositis), ARCA; Secreted proteins (GI and bone diseases),Kyowa Hakko Kirin/ARCA; Secreted proteins (IBD), Kirin/ARCA; Secreted proteins (inflammatory bowel disease), ARCA/Kirin; Secreted proteins (mucositis), Kirin/ARCA; Human R-Spondin-1 (GI and bone diseases), ARCA; Low-density lipoprotein receptor related protein 6 (IBD), Kirin/ARCA

Indication

Disease Entry	ICD 11	Status	REF
Gastrointestinal disease	DE2Z	Phase 1	[1]
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Cross-matching ID

TTD ID: D08JVS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Roof plate-specific spondin-1 (RSPO1)	TTI9HL4	RSPO1_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3697).
2	R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation.BMC Dev Biol.2008 Apr 2;8:36.