Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTHR4U)

Drug Name

ASM8 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Allergic asthma	CA23.0	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting CCR3 messenger RNA (CCR3 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
banyu (I)	DM9JXIZ	Discovery agent	N.A.	Investigative	[3]
RO116-9132/238	DM6XM1D	Discovery agent	N.A.	Investigative	[4]
RO320-2947/001	DM8BLYO	Discovery agent	N.A.	Investigative	[4]
RO116-4875/608	DMFTW0U	Discovery agent	N.A.	Investigative	[4]
RO330-0802/001	DMGOPY1	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01380236) A Single Blind Study to Evaluate the Safety, Tolerability and Explore the Efficacy of 8.0 mg ASM8 Inhaled Daily for 14 Days in Severe Asthma. U.S. National Institutesof Health.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 60).
3	Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002 Dec 5;456(1-3):1-10.
4	Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002 Jun 15;165(12):1602-9.