Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTUMYX)

Drug Name
AS-902330 Drug Info
Synonyms Sprifermin; Zfgf5; FGF-18, Merck Serono; FGF-18, ZymoGenetics
Indication
Disease Entry ICD 11 Status REF
Arthropathy FA11-FA38 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMTUMYX

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor-18 (FGF18) TT6ICRA FGF18_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT01919164) A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin (AS902330) in Patients With Osteoarthritis of the Knee. U.S. National Institutes of Health.
2 Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. Arthritis Rheumatol. 2014 Jul;66(7):1820-31.