Details of the Drug

General Information of Drug (ID: DMTUMYX)

Drug Name
AS-902330
Synonyms Sprifermin; Zfgf5; FGF-18, Merck Serono; FGF-18, ZymoGenetics
Indication
Disease Entry ICD 11 Status REF
Arthropathy FA11-FA38 Phase 2 [1]
Cross-matching ID
UNII
UEJ4E476ZP
DrugBank ID
DB12616
TTD ID
D04GKP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor-18 (FGF18) TT6ICRA FGF18_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01919164) A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin (AS902330) in Patients With Osteoarthritis of the Knee. U.S. National Institutes of Health.
2 Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. Arthritis Rheumatol. 2014 Jul;66(7):1820-31.