Details of the Drug

General Information of Drug (ID: DMTUMYX)

Drug Name

AS-902330

Synonyms

Sprifermin; Zfgf5; FGF-18, Merck Serono; FGF-18, ZymoGenetics

Indication

Disease Entry	ICD 11	Status	REF
Arthropathy	FA11-FA38	Phase 2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fibroblast growth factor-18 (FGF18)	TT6ICRA	FGF18_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01919164) A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin (AS902330) in Patients With Osteoarthritis of the Knee. U.S. National Institutes of Health.
2	Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. Arthritis Rheumatol. 2014 Jul;66(7):1820-31.