Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVZLIB)

Drug Name
AHL Drug Info
Synonyms AHLi-11; SiRNA therapeutics (hearing loss), Quark; P53 gene-silencing siRNA (hearing loss), Quark
Indication
Disease Entry ICD 11 Status REF
Hearing disorder AB50-AB57 Investigative [1]
Cross-matching ID
TTD Drug ID
DMVZLIB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting P53 messenger RNA (TP53 mRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
OPI-1002 DML6TAS Acute kidney injury GB60 Phase 2 [2]
Cenersen DMMN21R Acute myeloid leukaemia 2A60 Phase 2 [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
P53 messenger RNA (TP53 mRNA) TT12KOD P53_HUMAN Not Available [1]

References

1 Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia. Cancer. 2012 Jan 15;118(2):418-27.
2 2011 Pipeline of Quark Pharm.