Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ1YGI)

Drug Name

MCI Drug Info

Synonyms

AC1L1B35; CTK8A8774; (2-mercaptomethyl-4-phenyl-butyrylimino)-(5-tetrazol-1-ylmethyl-thiophen-2-yl)-acetic acid; 2-[4-phenyl-2-(sulfanylmethyl)butanoyl]imino-2-[5-(tetrazol-1-ylmethyl)thiophen-2-yl]acetic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 1263
TTD Drug ID: DMZ1YGI

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting 5-HT receptor (5HTR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Metergolin	DMJFP6G	Hyperprolactinaemia	5A60.1	Approved	[2]
Paliperidone	DM7NPJS	Psychotic disorder	6A20-6A25	Approved	[3]
Ramosetron	DMH7GN8	Diarrhea-predominant irritable bowel syndrome	DD91.01	Approved	[2]
Pizotyline	DMV74ZH	Headache	8A80-8A84	Approved	[3]
Tandospirone	DMPHWU6	Anxiety disorder	6B00-6B0Z	Approved	[2]
Nafronyl	DMVMQ1L	Cerebrovascular ischaemia	8B1Z	Approved	[3]
ITI-007	DMUQ1DO	Depression	6A70-6A7Z	Phase 3	[4]
Fenfluramine	DM0762O	Dravet syndrome	8A61.11	Phase 3	[5]
MIN-117	DMSLIW6	Major depressive disorder	6A70.3	Phase 2	[4]
Lu-AA34893	DM2ZUXK	Anxiety disorder	6B00-6B0Z	Phase 2	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT receptor (5HTR)	TT85JO3	NOUNIPROTAC	Antagonist	[1]

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References

1	Effect of a serotonin receptor antagonist on interleukin-6-induced pulmonary hypertension in rats. Chest. 2001 Feb;119(2):554-61.
2	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418.
6	Encyclopedia of Psychopharmacology. Ian Stolerman. 2010. Page(105).