Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZNUDT)

• Drug Name: Aurachin Drug Info
• Synonyms: Aurachin E; aurachin
• Cross-matching ID:
  PubChem CID: 13746957
  CAS Number: CAS 113366-10-2
  TTD Drug ID: DMZNUDT
  INTEDE Drug ID: DR2680

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 RauA (rauA) Main DME	DE1OW2F	S6BVH1_RHOER	Substrate	[1] , [2]

References

• [1] Structure of the quinoline N-hydroxylating cytochrome P450 RauA, an essential enzyme that confers antibiotic activity on aurachin alkaloids. FEBS Lett. 2014 Jan 3;588(1):105-10.
• [2] Rhodococcus erythropolis encephalitis in patient receiving rituximab. Emerg Infect Dis. 2012 Aug;18(8):1377-9.