Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMDSL4E)

• Drug Name: Azapropazone Drug Info
• Synonyms: Azapropazone; APAZONE; Cinnopropazone; Prolixan; Azapropazonum; Azapropazona; Cinnamin; Rheumox; Sinnamin; Mitrolan; Azapropazon; Prolix; Xani; Azapropazone (anhydrous); 13539-59-8; AHR-3018; Prolixan 300; MI 85; AHR 3018; Apazone [USAN]; Azapropazon [German]; Mi-85; NSC-102824; Azapropazonum [INN-Latin]; Azapropazona [INN-Spanish]; NSC 102824; 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione; C16H20N4O2; 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine; EINECS 236-9
• Cross-matching ID:
  PubChem CID: 26098
  ChEBI ID: CHEMBL38010
  CAS Number: CAS 13539-59-8
  TTD Drug ID: D01EQG

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Propanoate metabolism	1.96	2.46e-2	30/34 (88.24%)	ACAT2;SUCLG2;MMUT;...
Primary bile acid biosynthesis	1.89	3.08e-2	15/17 (88.24%)	CYP27A1;SLC27A5;AMACR;...
Mineral absorption	-2.01	7.22e-3	48/60 (80%)	SLC30A1;MT1M;HEPH;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲