Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMG5KDY)

• Drug Name: PYROGALLOL Drug Info
• Synonyms: pyrogallol; benzene-1,2,3-triol; 87-66-1; 1,2,3-trihydroxybenzene; pyrogallic acid; 1,2,3-benzenetriol; Fouramine Brown AP; fourrine PG; fourrine 85; Pyro; C.I. Oxidation Base 32; Piral; fouramine base ap; C.I. 76515; Benzenetriol; 1,2,3-Trihydroxybenzen; Benzene, 1,2,3-trihydroxy-; CI Oxidation Base 32; NSC 5035; UNII-01Y4A2QXY0; HSDB 794; CCRIS 1940; 2,3-Dihydroxyphenol; 1,2,3-Trihydroxybenzen [Czech]; 1,2,3-TRIHYDROXY-BENZENE; Pyrogallol, ACS reagent; EINECS 201-762-9; BRN 0907431; CI 76515; AI3-00709; CHEMBL307145; 01Y4A2QXY0
• Cross-matching ID:
  PubChem CID: 1057
  ChEBI ID: CHEMBL307145
  CAS Number: CAS 87-66-1
  TTD Drug ID: D06TPF
  INTEDE Drug ID: DR2253

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
B cell receptor signaling pathway	1.95	0.00e+0	71/81 (87.65%)	NFATC3;KRAS;BLNK;...
GABAergic synapse	1.88	3.06e-2	76/89 (85.39%)	SLC38A1;SRC;GAD1;...
Ferroptosis	1.82	3.68e-2	36/41 (87.8%)	HMOX1;FTH1;SAT1;...
African trypanosomiasis	-1.76	3.23e-2	32/37 (86.49%)	APOL1;APOA1;PRKCA;...
Autoimmune thyroid disease	-1.85	6.47e-3	46/53 (86.79%)	HLA-DPB1;HLA-E;HLA-A;...
Antigen processing and presentation	-1.89	2.02e-3	60/78 (76.92%)	HLA-E;B2M;HLA-A;...
Graft-versus-host disease	-1.93	2.69e-3	32/42 (76.19%)	HLA-DPB1;HLA-E;HLA-A;...
Viral myocarditis	-2.00	0.00e+0	53/60 (88.33%)	RAC1;HLA-DPB1;DMD;...
Allograft rejection	-2.01	0.00e+0	32/38 (84.21%)	HLA-DPB1;HLA-E;HLA-A;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	0.04uM - 10uM	24H	Hide ▲