| Glycolysis / Gluconeogenesis |
1.70 |
2.78e-1 |
56/67 (83.58%) |
ADH5;ALDH2;ENO2;...
|
| Primary immunodeficiency |
1.68 |
2.29e-1 |
33/38 (86.84%) |
BLNK;IGLL1;CD4;...
|
| Aldosterone-regulated sodium reabsorption |
1.65 |
2.13e-1 |
34/37 (91.89%) |
SCNN1A;IRS1;PRKCB;...
|
| Drug metabolism |
1.63 |
2.09e-1 |
78/151 (51.66%) |
ADH5;DPYD;CES1;...
|
| Thyroid hormone synthesis |
1.60 |
2.19e-1 |
66/75 (88%) |
GPX3;GNAS;CREB3L1;...
|
| beta-Alanine metabolism |
1.59 |
1.97e-1 |
25/30 (83.33%) |
ALDH2;DPYD;ALDH1B1;...
|
| Adrenergic signaling in cardiomyocytes |
1.58 |
2.04e-1 |
130/150 (86.67%) |
ACTC1;GNAS;CREB3L1;...
|
| Primary bile acid biosynthesis |
1.57 |
1.95e-1 |
15/17 (88.24%) |
ACOX2;AKR1D1;CH25H;...
|
| Cardiac muscle contraction |
1.57 |
1.81e-1 |
64/87 (73.56%) |
ACTC1;TPM2;TPM3;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
1.56 |
1.76e-1 |
49/53 (92.45%) |
GNAS;PRKCB;PLCB3;...
|
| Pancreatic secretion |
1.55 |
1.66e-1 |
87/102 (85.29%) |
GNAS;CLCA4;SLC4A4;...
|
| Dilated cardiomyopathy |
1.51 |
2.25e-1 |
86/96 (89.58%) |
ACTC1;GNAS;DES;...
|
| Thyroid hormone signaling pathway |
1.50 |
2.28e-1 |
112/121 (92.56%) |
PRKCB;PLCB3;RCAN2;...
|
| Pentose and glucuronate interconversions |
1.49 |
2.33e-1 |
17/34 (50%) |
AKR1A1;RPE;DCXR;...
|
| Other glycan degradation |
1.48 |
2.23e-1 |
13/18 (72.22%) |
AGA;MAN2B1;HEXA;...
|
| Systemic lupus erythematosus |
1.46 |
2.41e-1 |
45/135 (33.33%) |
C7;C1S;C1R;...
|
| Ascorbate and aldarate metabolism |
1.46 |
2.28e-1 |
15/30 (50%) |
ALDH2;ALDH1B1;AKR1A1
|
| Lysine degradation |
1.44 |
2.42e-1 |
51/63 (80.95%) |
ALDH2;BBOX1;PLOD2;...
|
| Propanoate metabolism |
1.44 |
2.36e-1 |
30/34 (88.24%) |
PCCA;SUCLG2;LDHB;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.42 |
2.69e-1 |
49/77 (63.64%) |
ADH5;GSTA1;GSTP1;...
|
| Basal transcription factors |
1.42 |
2.62e-1 |
37/45 (82.22%) |
TAF10;GTF2I;TAF15;...
|
| Nitrogen metabolism |
1.41 |
2.51e-1 |
16/17 (94.12%) |
CA12;GLUL;CA7;...
|
| Phosphonate and phosphinate metabolism |
1.40 |
2.72e-1 |
5/6 (83.33%) |
CHPT1;CEPT1
|
| Pantothenate and CoA biosynthesis |
1.38 |
2.92e-1 |
14/21 (66.67%) |
ALDH2;DPYD;ALDH1B1
|
| Arginine and proline metabolism |
1.38 |
2.88e-1 |
39/50 (78%) |
ALDH2;GATM;AOC1;...
|
| Central carbon metabolism in cancer |
1.37 |
2.89e-1 |
67/70 (95.71%) |
ERBB2;FGFR3;KIT;...
|
| Inositol phosphate metabolism |
1.37 |
2.79e-1 |
66/73 (90.41%) |
IMPA1;PLCB3;PIK3CG;...
|
| Ether lipid metabolism |
1.37 |
2.80e-1 |
32/49 (65.31%) |
CHPT1;PLAAT3;PLA2G10;...
|
| B cell receptor signaling pathway |
1.36 |
2.89e-1 |
71/81 (87.65%) |
CD81;BLNK;IFITM1;...
|
| Tyrosine metabolism |
1.35 |
2.99e-1 |
30/36 (83.33%) |
ADH5;TPO;ADH1C;...
|
| ECM-receptor interaction |
-1.25 |
5.97e-1 |
80/88 (90.91%) |
THBS4;TNN;LAMB1;...
|
| Glycosaminoglycan biosynthesis |
-1.27 |
5.90e-1 |
40/58 (68.97%) |
HS2ST1;CHST15;NDST1;...
|
| Malaria |
-1.27 |
6.06e-1 |
44/50 (88%) |
CSF3;THBS4;MYD88;...
|
| Fluid shear stress and atherosclerosis |
-1.30 |
5.26e-1 |
123/139 (88.49%) |
PDGFB;PDGFA;MGST3;...
|
| Protein export |
-1.30 |
5.44e-1 |
17/23 (73.91%) |
SEC61G;SEC63;HSPA5;...
|
| Adipocytokine signaling pathway |
-1.30 |
5.33e-1 |
64/69 (92.75%) |
TNFRSF1B;LEP;STAT3;...
|
| Measles |
-1.31 |
5.35e-1 |
133/139 (95.68%) |
MYD88;HSPA1L;MAVS;...
|
| Endocytosis |
-1.31 |
5.43e-1 |
198/252 (78.57%) |
HSPA1L;ACAP2;FOLR2;...
|
| Protein processing in endoplasmic reticulum |
-1.33 |
5.15e-1 |
127/171 (74.27%) |
RRBP1;SEC24C;PPP1R15A;...
|
| Ferroptosis |
-1.34 |
4.95e-1 |
36/41 (87.8%) |
SLC3A2;SLC7A11;PCBP1;...
|
| Apoptosis |
-1.35 |
4.87e-1 |
126/168 (75%) |
BAD;CASP7;AIFM1;...
|
| Purine metabolism |
-1.35 |
5.07e-1 |
102/129 (79.07%) |
PDE4C;NME1;ITPA;...
|
| Cytokine-cytokine receptor interaction |
-1.36 |
4.96e-1 |
246/295 (83.39%) |
IL10RA;TNFRSF25;GDF10;...
|
| Steroid biosynthesis |
-1.38 |
4.56e-1 |
19/20 (95%) |
SOAT1;CYP24A1;LSS;...
|
| Chemokine signaling pathway |
-1.40 |
4.27e-1 |
163/192 (84.9%) |
BAD;CCL1;CCL18;...
|
| Morphine addiction |
-1.41 |
3.93e-1 |
80/91 (87.91%) |
PDE8B;GNB2;GABRG3;...
|
| Amino sugar and nucleotide sugar metabolism |
-1.44 |
3.42e-1 |
38/48 (79.17%) |
GALT;PGM3;HK3;...
|
| Ovarian steroidogenesis |
-1.44 |
3.67e-1 |
41/51 (80.39%) |
IGF1;PLA2G4A;HSD17B7;...
|
| Lipid and atherosclerosis |
-1.49 |
2.61e-1 |
190/215 (88.37%) |
MYD88;HSPA1L;MAPK11;...
|
| PPAR signaling pathway |
-1.51 |
2.41e-1 |
66/74 (89.19%) |
HMGCS1;PLIN2;HMGCS2;...
|
| Toxoplasmosis |
-1.52 |
2.40e-1 |
103/112 (91.96%) |
MYD88;HSPA1L;LAMB1;...
|
| Riboflavin metabolism |
-1.52 |
2.65e-1 |
7/8 (87.5%) |
ACP1;ACP2;FLAD1
|
| Regulation of lipolysis in adipocytes |
-1.53 |
2.88e-1 |
52/55 (94.55%) |
PIK3R1;ABHD5;GNAI1;...
|
| IL-17 signaling pathway |
-1.54 |
3.04e-1 |
84/94 (89.36%) |
MMP1;IL17RC;CSF2;...
|
| Small cell lung cancer |
-1.57 |
2.67e-1 |
90/92 (97.83%) |
COL4A1;MAX;GADD45B;...
|
| Viral protein interaction with cytokine and cytokine re... |
-1.60 |
2.57e-1 |
84/100 (84%) |
ACKR4;CCL1;CCL18;...
|
| Ribosome biogenesis in eukaryotes |
-1.61 |
2.87e-1 |
52/108 (48.15%) |
NOP10;EIF6;NXF1;...
|
| Porphyrin and chlorophyll metabolism |
-1.67 |
1.98e-1 |
23/43 (53.49%) |
BLVRB;FECH;HMBS;...
|
| Legionellosis |
-1.74 |
1.63e-1 |
51/57 (89.47%) |
MYD88;HSPA1L;CD14;...
|
| TNF signaling pathway |
-1.78 |
2.27e-1 |
103/112 (91.96%) |
TRAF3;CASP7;ICAM1;...
|
