Details of the Drug

General Information of Drug (ID: DMM50ED)

Drug Name
IC87114
Synonyms
IC-87114; 371242-69-2; IC87114; 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one; IC 87114; UNII-9HC746B1KF; 2-[(6-AMINO-9H-PURIN-9-YL)METHYL]-5-METHYL-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE; 9HC746B1KF; CHEMBL1213082; CHEBI:90686; D-030; 2-[(6-aminopurin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one; 2-[(6-Amino-9h-Purin-9-Yl)methyl]-5-Methyl-3-(2-Methylphenyl)quinazolin-4(3h)-One; BiomolKI2_000002; GNWHRHGTIBRNSM-UHFFFAOYSA-N; PubChem22453; MLS006011148; SCHEMBL360745; GTPL9376; EX-A326
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 397.4
Logarithm of the Partition Coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C22H19N7O
IUPAC Name
2-[(6-aminopurin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one
Canonical SMILES
CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C(N=CN=C54)N
InChI
InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3,(H2,23,24,25)
InChIKey
GNWHRHGTIBRNSM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9908783
ChEBI ID
CHEBI:90686
CAS Number
371242-69-2
TTD ID
D00ZIK
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase delta (PIK3CD) TTGBPJE PK3CD_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase delta (PIK3CD) DTT PIK3CD 4.31E-16 -0.37 -0.91
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 6.6465 8.7004 3.6359 0.9334
EW-13 GDSC1 4.6965 16.0401 -1.2279 30.8023
NY GDSC1 5.0452 8.542 2.7801 9.6949
ES7 GDSC1 5.4574 11.2136 1.7705 15.378
H-EMC-SS GDSC1 5.725 8.4707 3.2674 4.3918
EW-24 GDSC1 5.7758 7.0778 3.8862 0.6111
NOS-1 [Human HNSCC] GDSC1 5.7897 9.9499 2.6171 8.8078
ES6 GDSC1 5.8652 8.1268 3.4995 2.592
CADO-ES1 GDSC1 5.9447 7.4258 3.825 0.7264
SK-PN-DW GDSC1 5.9924 8.2919 3.4955 2.413
HuO-3N1 GDSC1 6.1107 13.2618 1.2408 16.5746
EW-18 GDSC1 6.2557 8.6669 3.4709 2.1715
ES1 GDSC1 6.311 8.1561 3.7015 0.9392
EW-7 GDSC1 6.3142 9.3049 3.2294 3.5304
CHSA8926 GDSC1 6.3411 13.6301 1.2243 16.0386
CAL-72 GDSC1 6.3846 8.051 3.7717 0.6048
TC-71 GDSC1 6.3997 7.7515 3.8851 0.2581
EW-3 GDSC1 6.4891 10.1082 2.9729 4.8504
ES5 GDSC1 6.6367 11.4427 2.4558 7.9019
Hs 822.T CTRP2 6.7425 7.9565 5.5884 0.9164
EW-22 GDSC1 6.8439 8.7586 3.6941 0.5868
EW-1 GDSC1 6.8599 8.7681 3.6969 0.5688
MG-63 GDSC1; CTRP2 6.914 9.6399 4.9096 3.3296
A-673 GDSC1; CTRP2 6.9724 9.3358 5.0929 2.5227
SJSA-1 GDSC1; CTRP2 6.9744 8.599 4.5052 0.3744
ES8 GDSC1 7.0338 8.6286 3.8102 0.2138
ES4 GDSC1 7.082 8.9111 3.7299 0.3712
MHH-ES-1 GDSC1; CTRP2 7.344 9.3279 5.3174 1.2797
EW-16 GDSC1 7.476 9.5037 3.6673 0.3721
SaOS-2 GDSC1; CTRP2 7.6538 9.6931 5.3225 1.0056
SK-N-MC CTRP2 7.6764 8.5169 5.7766 0.0355
U2OS GDSC1; CTRP2 7.6892 13.3474 3.6562 7.2464
HuO9 GDSC1 7.7236 9.8908 3.6227 0.3856
Hs 888.T CTRP2 7.7706 20.6638 0.1187 19.5748
SK-ES-1 GDSC1; CTRP2 7.892 9.7973 5.3933 0.6483
TC71 CTRP2 8.0165 9.1843 5.6696 0.0855
G-292 clone A141B1 GDSC1; CTRP2 8.1061 12.7438 4.2173 4.4893
HOS GDSC1; CTRP2 8.1579 9.441 5.6318 0.1029
CAL-78 GDSC1; CTRP2 8.3162 14.1373 3.6984 6.2156
SW1353 CTRP2 12.0842 26.1297 0.4781 12.4325
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 6.7827 10.1702 4.5598 4.9513
MEC1 CTRP2 7.0282 8.5787 5.4728 1.0417
JM1 GDSC1; CTRP2 6.7387 8.1894 5.4804 1.3181
HAL-01 GDSC1 -1.2551 8.1117 -3.0975 58.5461
NK-92MI GDSC1 0.268 11.5242 -3.0376 50.2506
DoHH2 GDSC1 0.733 8.6838 -1.2751 47.42
JVM-2 GDSC1; CTRP2 0.9072 6.4624 0.3185 35.964
SU-DHL-16 GDSC1 0.9782 8.8181 -1.0863 45.8386
Ri-1 CTRP2 1.9495 10.6506 -0.1777 33.6821
SU-DHL-6 GDSC1; CTRP2 2.1369 9.2182 0.6323 30.9497
HuT 78 CTRP2 3.5594 17.6126 -1.9219 32.9879
HH [Human lymphoma] GDSC1 3.6335 19.143 -3.6698 38.7652
QIMR-WIL GDSC1 3.6665 17.5393 -2.8406 37.448
NU-DUL-1 GDSC1; CTRP2 3.8376 12.1285 1.0122 25.0047
HC-1 GDSC1 4.4995 21.1701 -3.9546 36.8538
SU-DHL-5 GDSC1 4.7851 11.3461 1.188 20.9581
Karpas-231 GDSC1 5.1153 17.0829 -1.41 30.0572
MV4-11 GDSC1; CTRP2 5.1581 14.8446 0.8855 22.2891
Hs 611.T CTRP2 5.2505 11.2744 2.7415 15.3935
Pfeiffer CTRP2 5.4078 12.4652 2.2892 16.8157
Ramos.2G6.4C10 GDSC1 5.4873 10.1317 2.3216 11.6789
RPMI-8226 GDSC1; CTRP2 5.4891 16.2676 0.463 22.8822
JSC-1 GDSC1 5.5078 8.1744 3.2715 4.8382
KE-37 GDSC1 5.5366 6.8595 3.8659 0.9396
BALL-1 GDSC1 5.5602 7.88 3.4382 3.5561
ML-2 GDSC1 5.5739 7.8697 3.4508 3.4424
EoL-1 GDSC1; CTRP2 5.6297 6.8392 5.2645 4.1773
Mono-Mac-6 GDSC1; CTRP2 5.637 10.6034 3.4171 11.8322
RCH-ACV GDSC1; CTRP2 5.6905 16.3968 0.5704 22.1364
NU-DHL-1 CTRP2 5.7002 17.0662 -0.4291 21.22
BL-41 GDSC1 5.7077 7.6083 3.6393 1.9844
PL-21 GDSC1 5.72 28.8953 -6.8199 37.6163
Loucy GDSC1 5.7317 8.3004 3.3485 3.8228
KMS-21-BM CTRP2 5.7491 7.7847 4.9173 5.3401
Farage GDSC1 5.7635 19.149 -1.9271 29.6457
EHEB GDSC1; CTRP2 5.7957 12.3639 2.6751 14.5076
TUR GDSC1 5.816 7.7073 3.6526 1.7464
YT GDSC1 5.8441 7.6353 3.6962 1.4645
WIL2 NS GDSC1 5.9577 10.7562 2.3447 10.2405
LC4-1 GDSC1 5.9593 14.255 0.6451 20.0404
Sc-1 GDSC1 5.9877 7.919 3.649 1.5381
Karpas-45 GDSC1 6.0161 12.5175 1.5358 15.1729
MOLT-16 GDSC1; CTRP2 6.0262 8.5096 4.7966 5.2801
ME1 GDSC1 6.0653 7.5393 3.8324 0.6015
CTV-1 GDSC1 6.0928 12.4146 1.6395 14.3525
KOPN-8 GDSC1 6.1382 13.7394 1.0276 17.6342
KY821 GDSC1 6.1392 8.2518 3.5855 1.6905
Jiyoye GDSC1 6.1409 8.024 3.678 1.2115
SUP-T1 GDSC1 6.1413 8.5373 3.4678 2.3526
OCI-Ly10 CTRP2 6.1467 8.221 5.0401 4.0282
Ku812 GDSC1; CTRP2 6.1525 14.3635 1.9746 16.4673
RC-K8 GDSC1 6.154 7.9988 3.6939 1.1217
RPMI-8866 GDSC1 6.1569 10.6074 2.5451 8.3984
U-698-M GDSC1 6.1993 10.3995 2.6688 7.4653
Karpas-422 GDSC1; CTRP2 6.2069 9.5736 4.4133 6.5484
EB2 GDSC1 6.212 8.0845 3.686 1.1006
H9 GDSC1 6.2511 12.3379 1.7854 13.055
MHH-PREB-1 GDSC1 6.2697 7.9176 3.7747 0.6735
BE-13 GDSC1 6.2727 8.2284 3.6566 1.1783
Daudi GDSC1; CTRP2 6.2745 8.4863 5.0095 3.9256
SU-DHL-4 GDSC1; CTRP2 6.2823 10.1376 4.1925 7.3349
GA-10 GDSC1; CTRP2 6.2879 8.4968 5.0147 3.8805
Toledo CTRP2 6.2935 10.7723 3.8847 8.6008
JVM-3 GDSC1; CTRP2 6.2998 8.5462 4.9995 3.9232
NCO2 CTRP2 6.3046 8.1516 5.199 3.0817
BC-3 GDSC1 6.3381 8.141 3.7188 0.843
Peer CTRP2 6.3385 8.2352 5.1834 3.0895
CESS GDSC1 6.3686 9.2134 3.2977 3.0219
OCI-Ly3 CTRP2 6.3832 9.0114 4.8329 4.4747
WSU-DLCL2 GDSC1; CTRP2 6.3857 8.932 4.8742 4.2979
SCC-3 GDSC1 6.4263 7.5114 3.9761 0.0865
THP-1 GDSC1; CTRP2 6.4567 10.078 4.3601 6.3221
IM-9 GDSC1 6.4704 7.6817 3.9342 0.1385
697 GDSC1; CTRP2 6.4853 9.6858 4.5768 5.3681
ALL-PO GDSC1 6.4945 25.4943 -4.5127 33.1404
VAL GDSC1 6.4946 13.1398 1.5658 13.7269
SU-DHL-10 GDSC1; CTRP2 6.5384 8.0848 5.4007 1.8874
KMOE-2 GDSC1 6.5432 8.2326 3.7679 0.5203
BC-1 GDSC1 6.5759 8.9537 3.5064 1.5873
P3HR-1 CTRP2 6.5981 8.5819 5.2022 2.6035
SK-MM-2 GDSC1; CTRP2 6.6234 8.9312 4.2057 1.5052
MOLM-6 CTRP2 6.6289 9.5059 4.7733 4.3152
P30/OHK GDSC1 6.631 19.5348 -1.4564 26.1583
MHH-CALL-3 CTRP2 6.6312 13.617 2.7353 12.6608
EB1 CTRP2 6.633 10.4683 4.3018 6.263
U-937 CTRP2 6.638 8.4203 5.3073 2.1224
A4/Fukuda GDSC1; CTRP2 6.645 7.9025 5.5554 1.1446
Hs 445 GDSC1 6.6496 18.5381 -0.9519 24.5343
SEM CTRP2 6.6582 8.0016 5.5177 1.2718
WSU-NHL GDSC1 6.6618 8.0279 3.8838 0.1782
MM1.S CTRP2 6.6753 8.4628 5.3119 2.0527
KMS-34 CTRP2 6.6828 10.9113 4.1203 6.9321
L-1236 GDSC1 6.7041 17.7465 -0.5234 22.9087
MN-60 GDSC1 6.7082 8.5405 3.7204 0.5796
OCI-AML-5 GDSC1; CTRP2 6.7674 7.8813 4.6846 0.119
KM-H2 GDSC1; CTRP2 6.7727 9.0933 5.0759 2.8613
MOTN-1 CTRP2 6.7766 8.5063 5.357 1.7439
L-363 GDSC1; CTRP2 6.7852 8.6785 5.2817 2.0264
MEG-01 GDSC1 6.7885 12.4049 2.1044 9.7861
OCI-AML-3 GDSC1; CTRP2 6.7924 8.1649 5.5236 1.0982
MC116 GDSC1; CTRP2 6.7976 9.705 4.7975 3.9536
CML-T1 CTRP2 6.8021 9.1844 5.0522 2.915
CTB-1 GDSC1 6.8174 28.05 -5.532 34.0051
RPMI-8402 GDSC1; CTRP2 6.8245 9.2017 5.059 2.8561
Granta-519 GDSC1; CTRP2 6.835 8.8973 5.2108 2.2396
KO52 CTRP2 6.8506 8.0212 5.6195 0.7062
KG-1 GDSC1 6.8554 8.4353 3.813 0.2613
RPMI-6666 GDSC1; CTRP2 6.8833 13.6468 2.9177 11.4912
L-428 GDSC1; CTRP2 6.9028 8.5954 4.4767 0.4718
ATN-1 GDSC1 6.9352 19.9938 -1.4572 25.4269
KMS-12-BM GDSC1; CTRP2 6.9391 9.9009 4.8013 3.7298
TK [Human B-cell lymphoma] GDSC1 6.9401 8.4717 3.8307 0.2014
REC-1 CTRP2 6.9428 10.1346 4.691 4.171
Kasumi-1 CTRP2 6.9484 9.3497 5.0708 2.6411
PL21 CTRP2 6.9572 10.4242 4.5607 4.6791
KMS-27 CTRP2 6.965 9.7377 4.8971 3.3082
MOLM-13 GDSC1; CTRP2 6.9661 10.8083 4.38 5.4035
KMS-28BM CTRP2 6.9741 10.0237 4.7661 3.8214
MLMA GDSC1 7.012 8.7163 3.7723 0.2976
SU-DHL-1 GDSC1; CTRP2 7.0227 9.8615 4.8767 3.31
SET-2 CTRP2 7.0501 8.3058 5.6011 0.6045
Mono-Mac-1 CTRP2 7.0694 13.415 3.1745 10.1491
L-540 GDSC1; CTRP2 7.0746 12.8835 3.4408 9.0683
P31/FUJ GDSC1; CTRP2 7.0782 10.3153 4.697 3.9517
BL-70 CTRP2 7.0812 8.3603 5.5938 0.6038
MOLM-16 CTRP2 7.0951 9.1439 5.2581 1.7436
AML-193 CTRP2 7.1163 9.2028 5.2438 1.7728
SUP-HD1 GDSC1; CTRP2 7.1296 8.9762 5.3536 1.36
ME1 CTRP2 7.1349 11.1412 4.3377 5.3206
HEL 92.1.7 CTRP2 7.171 8.5667 5.5524 0.6634
DEL GDSC1; CTRP2 7.1715 17.6232 1.1654 17.3855
Ki-JK CTRP2 7.1835 9.0039 5.3714 1.2445
NKM-1 GDSC1 7.1904 17.6029 -0.1066 20.109
EM-2 GDSC1; CTRP2 7.193 9.6034 5.1066 2.1988
DG-75 GDSC1 7.2459 9.0615 3.7373 0.2958
ARH-77 GDSC1 7.3352 8.8087 3.8534 0.0932
P32/ISH GDSC1 7.3501 19.3725 -0.8534 22.5123
MHH-CALL-4 CTRP2 7.3559 12.4806 3.843 6.9938
KE-97 CTRP2 7.377 11.2459 4.4528 4.5117
CCRF-CEM GDSC1 7.3805 18.6278 -0.4701 21.068
HEL GDSC1; CTRP2 7.3828 8.8752 5.5279 0.5904
RL GDSC1; CTRP2 7.385 8.7093 5.5949 0.4123
LP-1 GDSC1; CTRP2 7.4072 8.8388 5.5538 0.5054
KMM-1 CTRP2 7.413 11.2255 4.4864 4.3295
HDLM-2 GDSC1; CTRP2 7.4382 13.8307 3.2429 9.2739
KMS-18 CTRP2 7.4399 10.8364 4.6876 3.5048
HPB-ALL CTRP2 7.4424 9.4166 5.3315 1.146
OCI-Ly19 GDSC1; CTRP2 7.4454 8.9111 5.5424 0.5133
SIG-M5 GDSC1; CTRP2 7.4461 8.3292 5.7597 0.0806
NB4 GDSC1; CTRP2 7.4603 8.5012 5.7042 0.155
KMS-26 CTRP2 7.462 8.5969 5.67 0.2144
HT GDSC1; CTRP2 7.4903 15.6945 2.3649 12.5882
GR-ST GDSC1 7.5057 17.6192 0.1031 18.5006
SKM-1 GDSC1; CTRP2 7.5093 8.6183 5.6809 0.1797
TALL-1 [Human adult T-ALL] CTRP2 7.5163 10.2383 5.01 2.1957
SUP-T11 CTRP2 7.5603 12.9462 3.7606 7.0189
LAMA-84 GDSC1; CTRP2 7.5775 11.0069 4.6947 3.3071
P12-Ichikawa GDSC1; CTRP2 7.5972 9.0776 5.5446 0.4269
OPM-2 GDSC1; CTRP2 7.6526 9.1217 5.5515 0.3848
NCI-H929 CTRP2 7.6733 11.2843 4.6255 3.4555
HL-60 GDSC1; CTRP2 7.6832 9.1805 5.5419 0.3924
MOLT-4 GDSC1 7.6933 17.8513 0.1187 18.0054
ALL-SIL GDSC1; CTRP2 7.7088 9.5734 5.3985 0.7441
Jurkat GDSC1; CTRP2 7.7107 10.4502 5.0263 1.9378
KHM-1B CTRP2 7.7134 11.6193 4.4948 3.9078
DB GDSC1; CTRP2 7.7191 9.2846 5.5174 0.4321
SUP-M2 GDSC1; CTRP2 7.7322 8.9144 5.6599 0.1523
KCL-22 GDSC1; CTRP2 7.7356 10.0272 5.2232 1.2527
TF-1 CTRP2 7.7383 8.8585 5.6819 0.1203
Raji GDSC1; CTRP2 7.7598 12.4981 4.1108 5.3455
A3/Kawakami GDSC1; CTRP2 7.7663 8.8151 5.7071 0.0851
CMK CTRP2 7.7702 8.6703 5.7574 0.0401
KYO-1 CTRP2 7.7825 9.5232 5.4523 0.5577
AMO1 GDSC1; CTRP2 7.8368 8.986 5.6734 0.1114
Karpas-620 GDSC1; CTRP2 7.8447 9.1285 5.6261 0.1747
OCI-M1 GDSC1; CTRP2 7.9017 9.035 5.6799 0.0926
KMS-11 GDSC1; CTRP2 7.9289 10.1305 5.2763 0.9473
MOLT-13 GDSC1; CTRP2 7.9418 9.3807 5.5727 0.2342
OCI-AML-2 GDSC1; CTRP2 7.9451 9.8976 5.3776 0.6591
SUP-B15 GDSC1; CTRP2 7.9462 16.7743 2.1701 12.5665
VL51 GDSC1 7.9834 18.9026 -0.189 18.6195
Karpas-299 GDSC1; CTRP2 8.008 9.5937 5.5208 0.3065
GDM-1 GDSC1; CTRP2 8.0089 11.3366 4.8006 2.4379
HuNS1 CTRP2 8.0306 9.6947 5.4924 0.3537
CA46 GDSC1; CTRP2 8.046 9.7992 5.4595 0.4159
MOLT-3 CTRP2 8.0736 9.1196 5.7111 0.0444
EJM GDSC1; CTRP2 8.0925 9.4221 5.6148 0.1344
ST486 GDSC1; CTRP2 8.1027 9.5899 5.5593 0.2105
M-07e CTRP2 8.1097 9.8557 5.4646 0.3796
MY-M12 GDSC1 8.1587 22.1393 -1.6273 23.2074
F-36P CTRP2 8.1779 10.2076 5.3593 0.5826
Namalwa CTRP2 8.1958 9.6971 5.5563 0.1912
MOLP-8 GDSC1; CTRP2 8.2106 9.6638 5.5736 0.1635
DND-41 GDSC1; CTRP2 8.2296 12.7244 4.3021 4.0224
JURL-MK1 GDSC1; CTRP2 8.26 9.7499 5.5616 0.1689
JeKo-1 CTRP2 8.2866 9.4012 5.6898 0.0404
K-562 GDSC1; CTRP2 8.3382 9.5917 5.6439 0.0676
PF-382 GDSC1; CTRP2 8.3588 16.5516 2.5722 10.4495
HD-MY-Z CTRP2 8.4424 9.6511 5.6596 0.0466
U266B1 GDSC1; CTRP2 8.5049 10.1631 5.5069 0.1893
MOLP-2 CTRP2 8.5205 15.8455 3.0221 8.5275
SR GDSC1; CTRP2 8.5341 12.3936 4.626 2.5388
KMS-20 CTRP2 8.6599 11.4439 5.0882 1.0085
JJN-3 GDSC1; CTRP2 8.7067 10.5236 5.4549 0.2159
ROS-50 GDSC1 8.7207 23.3195 -1.8079 22.5966
RS4;11 GDSC1; CTRP2 9.0401 24.5798 -1.6268 18.908
NALM-6 GDSC1; CTRP2 9.0455 23.1518 -0.1554 18.2962
Reh GDSC1; CTRP2 9.1503 17.178 2.8044 8.491
BV-173 GDSC1; CTRP2 9.177 22.1579 0.4256 16.4299
Kasumi-2 CTRP2 9.3495 26.2159 -1.437 21.1134
NOMO-1 GDSC1; CTRP2 9.844 21.9483 0.9929 13.7351
SU-DHL-8 GDSC1; CTRP2 10.4426 22.5266 1.1174 12.5409
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 6.6223 8.9724 4.1872 1.5725
TE15 CTRP2 7.716 10.0945 5.1843 1.3955
TE-15 GDSC1 5.3166 11.2811 1.6325 16.6569
TE-8 GDSC1 5.6802 10.7428 2.161 12.2157
KYSE-270 GDSC1 6.2786 10.1899 2.8138 6.315
T.T GDSC1 6.3051 8.7143 3.4756 2.0782
TE-4 GDSC1; CTRP2 6.748 8.7352 4.3513 0.9136
TE-9 GDSC1; CTRP2 7.3558 8.8086 5.5421 0.5679
TE-1 GDSC1; CTRP2 7.4992 9.9441 5.132 1.7749
KYSE-150 GDSC1; CTRP2 7.6887 9.6486 5.3582 0.8732
KYSE-410 GDSC1; CTRP2 7.7472 13.1313 3.7999 6.592
KYSE-180 GDSC1; CTRP2 7.965 11.3399 4.7742 2.577
TE-6 GDSC1; CTRP2 7.9828 16.3886 1.5946 10.0831
KYSE-450 GDSC1; CTRP2 8.0345 11.0999 4.9192 2.0004
TE-14 CTRP2 8.096 20.5077 -0.3152 16.5894
OE19 GDSC1; CTRP2 8.1003 9.4017 5.6247 0.1208
KYSE-520 GDSC1; CTRP2 8.104 10.7759 5.0946 1.3672
TE-11 GDSC1; CTRP2 8.1187 9.6623 5.5393 0.2382
OE21 GDSC1; CTRP2 8.2093 10.1231 5.4051 0.4642
KYSE-30 CTRP2 8.2489 14.1973 3.6263 6.5825
COLO 680N GDSC1; CTRP2 8.2514 10.0071 5.4657 0.3261
KYSE-70 GDSC1; CTRP2 8.2721 12.8835 4.2548 4.1504
TE-10 GDSC1; CTRP2 8.3257 10.1683 5.4359 0.3563
EC-GI-10 GDSC1; CTRP2 8.4151 10.322 5.415 0.3647
OE33 GDSC1; CTRP2 8.5288 10.0907 5.541 0.1416
KYSE-510 GDSC1; CTRP2 8.5736 14.8344 3.536 6.5043
TE-5 GDSC1; CTRP2 8.5888 10.2535 5.5062 0.1726
KYSE-140 GDSC1; CTRP2 8.6071 12.4806 4.6276 2.4663
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.2971 10.7369 5.204 0.914
PL4 GDSC1 6.3742 8.4321 3.6218 1.2403
PSN1 GDSC1; CTRP2 6.746 8.8369 5.1806 2.4789
DAN-G GDSC1; CTRP2 6.7686 10.3344 4.469 5.3479
HuP-T4 GDSC1; CTRP2 6.7701 10.8575 4.2126 6.4048
MZ-PC-1 GDSC1 6.8725 10.0542 3.1989 2.8573
SW1990 GDSC1; CTRP2 7.067 9.9059 4.885 3.2169
CFPAC-1 GDSC1; CTRP2 7.1355 9.0447 5.3264 1.4511
BxPC-3 GDSC1; CTRP2 7.1628 10.8349 4.505 4.6032
SU.86.86 GDSC1; CTRP2 7.1744 8.7046 4.5455 0.2281
Panc 05.04 CTRP2 7.2296 12.547 3.7202 7.6859
PaTu 8988t GDSC1; CTRP2 7.2423 13.4453 3.2886 9.4062
Capan-1 GDSC1; CTRP2 7.3178 9.3531 5.292 1.3915
KP-1N GDSC1 7.3898 9.4389 3.6583 0.4265
SNU-213 CTRP2 7.4345 12.4738 3.9016 6.6396
Panc 10.05 GDSC1; CTRP2 7.4632 10.3509 4.9272 2.5611
SUIT-2 GDSC1; CTRP2 7.5072 9.0667 5.5086 0.5667
Capan-2 GDSC1; CTRP2 7.7172 12.4952 3.2403 3.9757
HuP-T3 GDSC1; CTRP2 7.7254 9.797 5.3148 0.9762
PaTu 8902 GDSC1; CTRP2 7.7334 8.7635 5.7131 0.084
HPAF-II GDSC1; CTRP2 7.7815 10.5049 5.0413 1.8177
YAPC GDSC1; CTRP2 7.7955 9.3141 5.5384 0.3517
L3.3 CTRP2 7.8022 9.3898 5.5125 0.4051
TCC-Pan2 CTRP2 7.8486 10.1279 5.2381 1.1182
PK-59 CTRP2 7.8574 12.5651 4.1429 5.0904
QGP-1 GDSC1; CTRP2 7.9512 9.3772 5.5776 0.2232
Hs 766T GDSC1; CTRP2 7.9652 12.6422 4.1759 4.8233
SNU-410 CTRP2 8.0365 12.016 4.5101 3.4664
PANC-1 CTRP2 8.0722 10.3217 5.2664 0.8817
MIA PaCa-2 GDSC1; CTRP2 8.1087 9.4191 5.6217 0.1228
HPAC GDSC1; CTRP2 8.1198 9.584 5.5678 0.1929
Panc 08.13 GDSC1; CTRP2 8.1356 9.9936 5.4233 0.4561
Panc 03.27 GDSC1; CTRP2 8.2486 13.4778 3.9648 5.2788
KP-3 GDSC1; CTRP2 8.3618 10.842 5.1918 0.9081
PK-45H CTRP2 8.4976 10.1435 5.5112 0.1852
PaTu 8988s CTRP2 8.7113 10.1675 5.5791 0.0782
KP-4 GDSC1; CTRP2 8.9802 18.2944 2.1596 11.05
AsPC-1 GDSC1; CTRP2 9.3965 11.0385 5.5222 0.0558
Panc 02.03 GDSC1; CTRP2 9.6954 16.7485 3.3421 5.8841
Panc 04.03 GDSC1; CTRP2 12.2695 23.077 1.9861 7.7082
KP-2 CTRP2 14.2127 27.828 0.9711 8.821
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.5124 10.8207 5.2672 0.638
COLO 783 GDSC1 5.322 7.1008 3.6509 2.5825
Hs 938.T GDSC1 5.5277 9.1514 2.8231 8.0234
VMRC-MELG GDSC1 5.5332 7.9696 3.3814 4.0059
MMAc-SF GDSC1 5.5501 7.1498 3.7528 1.5456
CP50-MEL-B GDSC1 5.8526 7.7002 3.6736 1.5776
IST-MEL1 GDSC1 5.9113 11.1119 2.1428 11.7012
CHL-1 GDSC1 6.0096 7.8762 3.6767 1.3648
CP66-MEL GDSC1 6.0274 7.4324 3.8569 0.5368
LB373-MEL-D GDSC1 6.0519 17.7654 -1.0182 26.2922
G-mel GDSC1 6.1259 7.5651 3.8474 0.5053
DJM-1 GDSC1 6.1923 8.1242 3.6616 1.2373
COLO 679 GDSC1 6.2012 8.3945 3.5568 1.7669
GAK GDSC1 6.2205 7.4589 3.9216 0.2385
A-431 GDSC1 6.2394 16.3039 -0.1559 22.7295
MZ-MEL-7 GDSC1 6.2643 8.4515 3.5636 1.6529
WM115 GDSC1; CTRP2 6.3904 11.2608 3.7187 9.1138
WM278 GDSC1 6.4022 8.5441 3.5902 1.3629
LB2518-MEL GDSC1 6.421 7.7692 3.8867 0.2467
WM1552C GDSC1 6.4795 8.0831 3.7973 0.4626
RPMI-7951 GDSC1; CTRP2 6.6182 11.6323 3.713 8.7301
SK-MEL-3 GDSC1; CTRP2 6.6421 8.1584 5.4343 1.6143
SH-4 GDSC1 6.7565 8.4048 3.7874 0.3584
451Lu GDSC1 6.7936 8.6808 3.7027 0.5876
UACC-62 GDSC1; CTRP2 6.8088 8.8119 5.2341 2.1822
WM35 GDSC1 6.8261 8.9194 3.6278 0.8299
SK-MEL-28 GDSC1; CTRP2 6.8556 9.8103 4.7871 3.9092
M14 GDSC1 6.8571 8.3602 3.8394 0.2077
IGR-39 CTRP2 6.9045 9.3255 5.0533 2.7688
IGR-1 GDSC1; CTRP2 7.0073 11.3475 4.1462 6.2972
WT2-iPS GDSC1; CTRP2 7.0511 9.0864 5.258 1.7935
WM1799 CTRP2 7.0907 9.9921 4.8597 3.2853
A-388 GDSC1 7.1111 9.1855 3.6432 0.5994
COLO 800 GDSC1; CTRP2 7.1684 9.143 5.3013 1.5072
SK-MEL-2 GDSC1; CTRP2 7.2391 8.3154 5.6839 0.273
Mel Ho GDSC1; CTRP2 7.2616 11.4226 4.2897 5.3285
HMV-II GDSC1 7.2709 9.2704 3.6735 0.4366
Hs 895.T CTRP2 7.3052 10.8111 4.6122 3.9768
K029AX CTRP2 7.3126 8.7907 5.5289 0.6334
Hs 688(A).T CTRP2 7.3229 14.7624 2.6996 11.5934
Hs 839.T CTRP2 7.3405 10.3442 4.8547 2.9826
MZ-MEL-2 GDSC1 7.4196 9.0646 3.797 0.1482
Hs 940.T GDSC1; CTRP2 7.4459 12.4822 3.9054 6.6072
Malme-3M CTRP2 7.4696 11.0784 4.5929 3.8357
MDA-MB-435S CTRP2 7.5233 11.273 4.5359 3.989
IPC-298 GDSC1; CTRP2 7.541 8.9952 5.552 0.4372
SK-MEL-1 GDSC1; CTRP2 7.5657 8.6605 5.6874 0.1531
CJM [Human melanoma] CTRP2 7.6256 8.8826 5.6301 0.233
G-361 GDSC1; CTRP2 7.6306 11.4214 4.5349 3.8563
HMCB CTRP2 7.6431 8.5107 5.7673 0.0455
Hs 934.T CTRP2 7.751 8.9103 5.6684 0.1358
WM266-4 CTRP2 7.7947 12.8325 3.9748 5.834
SK-MEL-31 CTRP2 7.7999 9.1081 5.6163 0.2026
Mel JuSo GDSC1; CTRP2 7.8194 9.2582 5.5691 0.2809
SK-MEL-24 GDSC1; CTRP2 7.8267 11.6373 4.5568 3.5334
HT-144 GDSC1; CTRP2 7.8544 12.7565 4.0504 5.4562
IGR-37 GDSC1; CTRP2 7.8651 8.9366 5.7006 0.0768
A2058 GDSC1; CTRP2 7.8901 9.2843 5.5875 0.2245
LOX-IMVI GDSC1; CTRP2 7.8941 9.4724 5.5197 0.3511
WM88 CTRP2 7.8944 9.4479 5.5289 0.3321
Hs 936.T CTRP2 7.9026 8.9026 5.7251 0.0507
SK-MEL-30 GDSC1; CTRP2 7.9233 9.2559 5.6105 0.1784
SK-MEL-5 GDSC1; CTRP2 8 9.3975 5.589 0.1914
COLO 741 CTRP2 8.0433 16.0583 2.5897 10.859
COLO 829 GDSC1; CTRP2 8.1113 13.108 4.0506 5.1217
A-375 GDSC1; CTRP2 8.1246 9.5638 5.5768 0.1785
Hs 944.T CTRP2 8.3133 15.0005 3.2869 7.8043
Hs 852.T CTRP2 8.3338 10.0549 5.4807 0.2733
COLO 792 GDSC1; CTRP2 8.3374 9.8052 5.5707 0.1415
UACC-257 GDSC1; CTRP2 8.351 9.6926 5.6142 0.092
RVH-421 GDSC1; CTRP2 8.3755 13.3376 4.1089 4.5775
WM793 GDSC1; CTRP2 8.5777 15.2435 3.3459 7.2215
Hs 294T CTRP2 8.8773 15.6373 3.3532 6.8083
WM983B CTRP2 9.0925 10.6458 5.5497 0.0627
A101D GDSC1; CTRP2 9.1951 15.9858 3.3896 6.2853
MeWo GDSC1; CTRP2 9.5942 16.664 3.3202 6.0752
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 5.3555 7.81 3.3456 4.6585
HCE-4 GDSC1 6.4175 13.7628 1.2133 15.8956
OACP4 C GDSC1 6.4773 10.2996 2.8808 5.4684
SK-GT-4 GDSC1 6.7074 10.7386 2.8159 5.4465
KYSE-220 GDSC1 6.884 9.1694 3.5576 1.0621
ESO-26 GDSC1 6.8995 8.3731 3.8499 0.1776
KYSE-50 GDSC1 6.9863 15.3225 0.8524 16.3154
FLO-1 GDSC1 7.0085 16.8311 0.1402 19.5312
OACM5.1 C GDSC1 7.035 14.1032 1.4654 12.9756
TE-12 GDSC1 7.2898 14.493 1.4458 12.4981
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 6.9162 10.0623 4.7075 4.1431
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-10 GDSC1 4.9562 6.6864 3.6173 3.6357
NB69 GDSC1 5.8711 8.3255 3.4161 3.1115
SK-N-MC-IXC GDSC1 5.9147 7.1008 3.9338 0.344
CHP-134 GDSC1 6.2556 8.1967 3.6614 1.1728
SJNB-14 GDSC1 6.4802 7.7904 3.9006 0.1972
SJNB-6 GDSC1 6.5555 8.1249 3.8113 0.3832
TGW GDSC1 6.5704 8.0574 3.8407 0.2998
NB(TU)1 GDSC1 6.6364 8.2823 3.7859 0.4166
SK-N-BE(2)-M17 GDSC1 6.6389 8.4592 3.7228 0.6132
LA-N-6 GDSC1 6.7079 8.3013 3.8059 0.3316
GOTO GDSC1 6.7999 10.6746 2.8956 4.7782
SJNB-17 GDSC1 6.8481 8.774 3.6902 0.5971
NH-12 GDSC1 6.8518 8.6335 3.7422 0.438
Kelly GDSC1; CTRP2 6.8802 8.6837 5.3392 1.6864
GI-ME-N GDSC1 6.8899 9.4967 3.4334 1.6097
SJNB-7 GDSC1 6.9303 8.3273 3.876 0.1304
SJNB-12 GDSC1 6.9417 8.8187 3.7101 0.4861
SJNB-5 GDSC1 6.951 8.44 3.8453 0.1732
IMR-5 GDSC1 6.9527 8.3094 3.8896 0.1082
SJNB-13 GDSC1 7.0142 8.6059 3.811 0.2176
NH-6 CTRP2 7.2895 9.063 5.4029 1.042
KP-N-YS GDSC1 7.4646 9.2461 3.7516 0.2079
IMR-32 CTRP2 7.5798 8.8555 5.6217 0.2654
SK-N-DZ GDSC1; CTRP2 7.6406 9.0089 5.5892 0.308
SK-N-BE(2) CTRP2 7.6661 11.3449 4.5928 3.5892
SK-N-FI GDSC1; CTRP2 7.768 9.7746 5.3447 0.8581
MHH-NB-11 GDSC1; CTRP2 7.8101 9.4686 5.4857 0.4627
SK-N-AS GDSC1; CTRP2 7.8203 9.1948 5.5928 0.2369
SK-N-SH GDSC1; CTRP2 7.8963 9.6221 5.4637 0.4731
CHP-212 GDSC1; CTRP2 8.0791 9.5417 5.5675 0.2039
CHP-126 CTRP2 8.088 9.5391 5.5718 0.1949
KP-N-SI9s CTRP2 8.1122 9.6916 5.5262 0.2624
SiMa GDSC1; CTRP2 8.1286 10.3043 5.2995 0.7586
KP-N-YN GDSC1; CTRP2 8.4345 10.2856 5.4361 0.3196
NB1 GDSC1; CTRP2 8.4987 9.9269 5.5865 0.0981
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 6.3689 12.0439 3.3106 10.8348
HuH-28 CTRP2 6.9073 8.9272 5.243 2.022
HuCC-T1 GDSC1; CTRP2 7.0828 10.0775 4.8138 3.4783
SNU-478 CTRP2 7.109 11.0705 4.3538 5.2938
SNU-308 CTRP2 7.2859 9.0345 5.4133 1.0111
SNU-1196 CTRP2 7.5319 9.6806 5.2652 1.2873
SNU-869 CTRP2 7.9287 9.4068 5.558 0.2643
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1 5.369 12.5157 1.0616 19.7182
Evsa-T GDSC1 5.3983 9.4503 2.59 10.0513
COLO 824 GDSC1 5.4025 8.7452 2.9331 7.5543
OCUB-M GDSC1 5.6504 7.849 3.5038 2.9399
UACC-812 GDSC1 5.7489 9.747 2.6866 8.4251
CAL-120 GDSC1 5.8293 7.1627 3.8765 0.6078
MDA-MB-175-VII GDSC1 5.9254 11.3366 2.0443 12.3023
BT-483 GDSC1 6.1407 7.7526 3.7833 0.738
HCC1187 GDSC1 6.291 14.9239 0.559 19.5233
HCC1569 GDSC1 6.3178 12.0379 1.9737 11.7243
MRK-nu-1 GDSC1 6.3185 8.1901 3.6916 0.9753
EFM-19 GDSC1 6.4209 9.2093 3.3264 2.7709
MDA-MB-231 GDSC1; CTRP2 6.5565 8.9904 4.9734 3.6046
MDA-MB-468 GDSC1; CTRP2 6.64 12.5243 3.2864 10.4405
Hs 578T GDSC1; CTRP2 6.666 9.3122 4.8951 3.7551
HCC1395 GDSC1; CTRP2 6.6844 10.043 4.5502 5.1479
UACC-893 GDSC1 6.7403 10.8625 2.7794 5.6164
MDA-MB-415 GDSC1 6.7441 20.6464 -1.9201 27.1928
MCF-7 GDSC1; CTRP2 6.7692 9.2435 5.0012 3.1678
DU4475 GDSC1; CTRP2 6.8319 8.7701 5.2687 2.0171
HCC38 GDSC1; CTRP2 6.9477 9.6746 4.9157 3.2577
HCC70 GDSC1 6.9738 21.9684 -2.4006 27.897
AU565 GDSC1; CTRP2 6.978 9.4819 5.0275 2.7725
HCC1500 GDSC1; CTRP2 7.0041 8.6251 5.4389 1.1836
KPL-1 CTRP2 7.0811 7.7766 5.8191 0.0782
HMC-1-8 CTRP2 7.2657 8.9316 5.4467 0.9197
BT-20 GDSC1; CTRP2 7.3052 8.9192 5.4721 0.8087
HCC1806 GDSC1; CTRP2 7.3616 8.8714 5.5194 0.628
Hs 578Bst CTRP2 7.4519 9.4431 5.3251 1.1588
HCC1143 CTRP2 7.4855 12.1496 4.0933 5.7954
ZR-75-30 GDSC1; CTRP2 7.5595 10.6422 4.8519 2.7329
HCC2218 GDSC1; CTRP2 7.6041 9.3383 5.4444 0.6825
CAL-148 GDSC1; CTRP2 7.6249 9.1265 5.5377 0.4297
MDA-MB-330 GDSC1 7.6252 15.443 1.2141 12.9937
CAL-51 GDSC1; CTRP2 7.6585 9.967 5.2088 1.3642
MDA-MB-361 GDSC1; CTRP2 7.7763 12.6685 3.1965 4.0773
MDA-MB-453 GDSC1; CTRP2 7.778 10.5585 5.0159 1.9091
HCC1599 GDSC1 7.7903 16.4511 0.8468 14.4826
JIMT-1 CTRP2 7.8241 9.1941 5.5945 0.2326
HDQ-P1 GDSC1; CTRP2 7.8648 9.4941 5.4992 0.407
BT-474 GDSC1; CTRP2 7.8725 9.4166 5.5317 0.335
HCC1419 GDSC1; CTRP2 7.8801 9.6341 5.452 0.5083
ZR-75-1 CTRP2 8.0223 9.4102 5.5929 0.1799
YMB-1-E GDSC1 8.0611 16.6083 0.9449 13.4247
BT-549 GDSC1; CTRP2 8.1137 13.675 3.7851 6.1466
MDA-MB-436 GDSC1 8.1356 19.0654 -0.165 18.1944
EFM-192A GDSC1; CTRP2 8.2589 9.692 5.5815 0.1433
HCC1428 GDSC1; CTRP2 8.5478 9.7943 5.6478 0.0455
CAL-85-1 GDSC1; CTRP2 8.6269 10.7258 5.3508 0.4126
MDA-MB-157 GDSC1; CTRP2 8.7622 17.7288 2.2827 10.9212
HCC202 GDSC1; CTRP2 8.8209 10.781 5.4064 0.2588
T-47D GDSC1; CTRP2 9.0591 13.8704 4.2664 3.2794
HCC1954 GDSC1; CTRP2 9.7667 18.0455 2.7894 7.7719
CAMA-1 GDSC1; CTRP2 10.1803 26.919 -1.1791 19.2964
HCC1937 GDSC1; CTRP2 10.1835 19.7665 2.2496 9.1501
SK-BR-3 CTRP2 10.2527 23.282 0.6304 14.2855
MFM-223 GDSC1 10.664 25.623 -1.6212 18.4957
BT 179 CTRP2 6.7299 7.9815 5.5699 0.9961
BT 504 CTRP2 7.1026 8.3913 5.5915 0.5953
BT 359 CTRP2 7.1163 9.4764 5.1182 2.2457
BT 440 CTRP2 7.1718 8.9213 5.4013 1.1526
BT 328 CTRP2 7.1977 8.4421 5.616 0.4628
BT 482 CTRP2 7.2897 8.9456 5.4531 0.88
BT 320 CTRP2 7.2939 10.7888 4.6153 3.9795
BT 330 CTRP2 7.4125 8.7934 5.5741 0.4496
BT 498 CTRP2 7.4874 9.2999 5.4038 0.8812
BT 422 CTRP2 7.5839 8.5922 5.7184 0.1049
BT164 CTRP2 7.6025 8.8469 5.634 0.2335
BT 172 CTRP2 7.6157 9.1176 5.5371 0.4356
BT 232 CTRP2 7.6625 9.3686 5.4593 0.6067
BT 340 CTRP2 7.7365 8.7943 5.7036 0.094
BT 112 CTRP2 7.783 9.0797 5.62 0.2014
BT 239 CTRP2 7.8003 13.4433 3.6863 6.9666
BT 224 CTRP2 7.8123 9.3871 5.5178 0.389
BT 444 CTRP2 7.827 9.1309 5.6185 0.1914
BT 139 CTRP2 7.9372 10.5281 5.1142 1.438
BT 428 CTRP2 7.9554 10.1965 5.2619 0.9709
BT 333 CTRP2 8.004 9.2305 5.6492 0.1095
BT 145 CTRP2 8.0126 9.5424 5.5415 0.2668
BT 271 CTRP2 8.0315 9.5873 5.5325 0.2768
BT 245 CTRP2 8.0391 9.3902 5.6063 0.1568
BT 131 CTRP2 8.0417 9.4191 5.5971 0.1692
BT 216 CTRP2 8.1316 9.7676 5.5061 0.2919
BT147 CTRP2 8.139 9.6474 5.5525 0.2114
BT 286 CTRP2 8.2237 9.5472 5.6188 0.1063
BT 231 CTRP2 8.2712 12.9965 4.2022 4.3488
BT 187 CTRP2 8.2865 11.6989 4.7946 2.1926
BT 159 CTRP2 8.6575 14.0518 3.9521 4.8345
BT 228 CTRP2 12.2905 24.0957 1.5398 9.0604
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.0115 9.114 5.2212 1.9787
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 5.6926 10.3847 2.3428 10.9581
D-263MG GDSC1 5.9183 15.5591 -0.0281 23.1074
MOG-G-CCM GDSC1 5.9755 8.5065 3.394 3.0707
D-566MG GDSC1 5.9991 7.7953 3.7044 1.2355
D-423MG GDSC1 6.0723 10.0406 2.7563 7.1597
D-247MG GDSC1 6.1381 10.7565 2.4631 8.9948
KNS-60 CTRP2 6.3244 8.2217 4.353 1.2612
KINGS-1 GDSC1 6.4128 9.5791 3.1634 3.7763
KNS-81 CTRP2 6.4414 7.9561 4.5226 0.6092
LNZTA3WT4 GDSC1 6.4557 7.9918 3.821 0.4036
M059J GDSC1 6.4921 8.3013 3.7222 0.7124
D-502MG GDSC1 6.4952 17.0177 -0.3184 22.6802
KS-1 [Human Krukenberg tumour] GDSC1 6.5136 9.5657 3.2226 3.2474
KNS-81-FD GDSC1 6.5234 8.5623 3.6364 1.034
D-542MG GDSC1 6.5845 15.3945 0.5392 18.8347
SK-MG-1 GDSC1 6.5974 8.2786 3.7723 0.4766
MOG-G-UVW GDSC1 6.7486 8.5458 3.7342 0.5131
LN-405 GDSC1 6.7836 8.4713 3.7741 0.3818
H4 GDSC1 6.8186 8.7337 3.6933 0.604
SNU-626 CTRP2 6.8514 9.3261 5.0176 2.9845
CCF-STTG1 CTRP2 6.9139 8.5333 5.4281 1.3161
D-336MG GDSC1 6.9181 9.1269 3.5878 0.9152
Hs 683 GDSC1; CTRP2 6.9232 9.5944 4.9376 3.2046
TM-31 CTRP2 6.9384 9.2443 5.1141 2.484
M059K CTRP2 6.9482 8.2262 5.5828 0.7432
SNU-466 CTRP2 7.0145 9.7707 4.9145 3.1711
SNU-489 CTRP2 7.0243 10.5777 4.5333 4.6905
Onda 11 GDSC1 7.0244 8.9604 3.6909 0.5011
GaMG GDSC1; CTRP2 7.075 10.9224 4.4017 5.1498
GMS-10 CTRP2 7.1017 10.1528 4.7905 3.5453
LN-18 GDSC1; CTRP2 7.1661 8.5786 5.545 0.6895
SF126 GDSC1; CTRP2 7.2027 9.9389 4.957 2.7588
SNU-201 CTRP2 7.2281 9.3589 5.2387 1.6706
PFSK-1 GDSC1 7.2489 9.2083 3.6872 0.4108
DK-MG GDSC1; CTRP2 7.2624 8.6821 5.5492 0.6085
GB-1 GDSC1; CTRP2 7.2703 11.836 4.0957 6.1003
T98G GDSC1; CTRP2 7.2793 9.6348 5.1441 1.9611
Onda 10 GDSC1 7.3338 9.0353 3.7773 0.196
U-251MG GDSC1; CTRP2 7.3705 10.3831 4.8554 2.9429
KNS-42 GDSC1; CTRP2 7.3741 8.9302 5.5013 0.6715
SF295 GDSC1; CTRP2 7.4226 9.0404 5.4795 0.702
D-392MG GDSC1 7.5234 9.639 3.6374 0.4252
NMC-G1 GDSC1; CTRP2 7.5584 10.0572 5.1151 1.7758
Becker GDSC1; CTRP2 7.6378 10.0104 5.179 1.4812
CAS-1 GDSC1; CTRP2 7.6553 12.4382 4.0698 5.65
SF539 GDSC1; CTRP2 7.6593 11.3751 4.5746 3.6677
SW1088 GDSC1; CTRP2 7.6745 14.0178 3.321 8.5979
SF268 GDSC1; CTRP2 7.691 11.5198 4.527 3.8113
AM-38 GDSC1; CTRP2 7.7049 9.3761 5.4755 0.5411
KG-1-C CTRP2 7.7088 10.8227 4.8585 2.5422
SNU-738 CTRP2 7.777 9.1295 5.5996 0.2387
D283 Med GDSC1; CTRP2 7.8313 9.2695 5.5697 0.2756
ONS-76 GDSC1; CTRP2 7.8614 13.2613 3.8148 6.373
YKG-1 GDSC1; CTRP2 7.9802 10.9552 4.9528 1.9358
KALS-1 GDSC1; CTRP2 8.0596 12.8787 4.1252 4.8996
SNU-1105 CTRP2 8.0969 17.8015 1.7763 13.7346
LN-229 GDSC1; CTRP2 8.1424 9.704 5.5335 0.241
8-MG-BA GDSC1; CTRP2 8.223 9.8191 5.523 0.2353
GOS-3 CTRP2 8.2405 9.6103 5.6032 0.1208
A-172 GDSC1; CTRP2 8.3436 9.9581 5.5191 0.2097
SW1783 GDSC1; CTRP2 8.7178 10.7028 5.3951 0.3042
SNB-75 GDSC1; CTRP2 8.8531 16.5722 2.0604 7.1484
YH-13 GDSC1; CTRP2 9.0302 15.2899 3.6095 5.6704
DBTRG-05MG GDSC1; CTRP2 9.8293 18.4889 2.6224 8.2873
42-MG-BA GDSC1; CTRP2 9.9382 17.2244 3.2693 5.876
U-87MG ATCC GDSC1; CTRP2 12.0066 22.7075 2.0007 7.9276
Daoy GDSC1; CTRP2 12.4834 21.4797 2.8022 4.9989
U-118MG GDSC1; CTRP2 12.5939 25.0006 1.3083 9.4412
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 6.3974 7.8877 3.836 0.3886
ETK-1 GDSC1 6.4132 8.6214 3.5645 1.4772
TGBC24TKB GDSC1 6.6524 9.1055 3.4809 1.6299
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 6.17 11.4611 2.1501 10.978
JHUEM-7 CTRP2 6.8572 8.6672 5.3326 1.7391
JHUEM-3 CTRP2 7.2134 9.1565 5.3208 1.3925
MFE-296 GDSC1; CTRP2 7.2451 8.8595 4.517 0.256
HEC-1-B CTRP2 7.2683 13.6581 3.2032 9.7053
HEC-265 CTRP2 7.2799 8.6766 5.5598 0.5668
JHUEM-1 CTRP2 7.3669 8.4971 5.6686 0.2524
JHUEM-2 CTRP2 7.3922 9.7578 5.1543 1.804
RL95-2 GDSC1; CTRP2 7.5171 10.4316 4.9227 2.5165
HEC-59 CTRP2 7.5493 10.2141 5.04 2.0519
MFE-319 GDSC1; CTRP2 7.6401 10.0488 5.1636 1.5311
HEC-251 CTRP2 7.804 9.309 5.5439 0.3369
AN3-CA GDSC1; CTRP2 7.9277 9.6833 5.4536 0.4816
HEC-151 CTRP2 7.9364 9.4675 5.5387 0.2976
HEC-6 CTRP2 8.1065 9.3386 5.6487 0.0933
HEC-108 CTRP2 8.2112 9.4545 5.6461 0.081
EN GDSC1; CTRP2 8.2761 9.7677 5.5613 0.1659
EFE-184 CTRP2 8.3084 11.2672 4.9912 1.5314
HEC-50B CTRP2 8.3576 10.818 5.1994 0.8901
ESS-1 GDSC1; CTRP2 8.3915 9.9179 5.5511 0.1552
KLE GDSC1; CTRP2 8.5317 10.1926 5.5065 0.1841
HEC-1-A CTRP2 8.6343 11.2092 5.1695 0.8126
Ishikawa (Heraklio) 02 ER- CTRP2 7.6934 8.5088 5.785 0.0289
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RXF 393L GDSC1 5.577 8.3318 3.2413 4.8957
NCC021 GDSC1 5.6173 9.8819 2.5334 9.8463
SW13 GDSC1 5.7749 7.9115 3.5445 2.4606
KTCTL-26A GDSC1 5.9479 14.1553 0.6858 19.8787
BFTC-909 GDSC1 5.9936 8.0735 3.5882 1.8674
SW156 GDSC1 6.0247 10.0022 2.7444 7.3517
KTCTL-195 GDSC1 6.19 8.4613 3.5239 1.9626
KTCTL-21 GDSC1 6.2523 10.7042 2.5603 8.0735
A-704 GDSC1 6.4148 8.2552 3.7076 0.8271
TK-10 GDSC1 6.4502 13.8576 1.1901 15.9345
TUHR10TKB CTRP2 6.5802 11.9024 3.549 9.473
KMRC-1 GDSC1; CTRP2 6.7835 8.1412 5.5291 1.0877
LB996-RCC GDSC1 6.9533 13.2505 1.8137 11.1682
KTCTL-1M GDSC1 6.9646 17.1284 -0.035 20.3693
A-498 GDSC1; CTRP2 6.9705 8.6421 5.412 1.3144
KMRC-20 GDSC1; CTRP2 7.0949 10.8735 4.4394 4.9673
RCC10RGB GDSC1; CTRP2 7.1072 9.626 5.0429 2.546
KTCTL-140 GDSC1 7.1119 15.8042 0.7066 16.7197
LB2241-RCC GDSC1 7.3019 15.5272 0.9657 14.9957
TUHR4TKB CTRP2 7.3193 13.3418 3.396 8.8518
LB1047-RCC GDSC1 7.3666 9.6935 3.5584 0.7261
KMRC-2 CTRP2 7.5477 10.8916 4.7296 3.2094
Caki-2 CTRP2 7.5717 9.1372 5.5099 0.5263
769-P GDSC1; CTRP2 7.6329 10.3658 5.02 2.0379
VMRC-RCW GDSC1; CTRP2 7.6539 9.4007 5.4425 0.6569
CAL-54 GDSC1; CTRP2 7.7446 14.5855 3.0945 9.3811
OS-RC-2 GDSC1; CTRP2 7.8024 14.6802 3.0894 9.3125
BB65-RCC GDSC1 7.8511 19.8729 -0.7451 20.9978
786-O GDSC1; CTRP2 7.9092 11.141 4.8312 2.4299
KMRC-3 CTRP2 7.9669 12.6806 4.159 4.8863
SN12C GDSC1 8.1052 20.3728 -0.8114 20.6781
KTCTL-13 GDSC1 8.2916 19.2808 -0.1642 17.8586
HA7-RCC GDSC1 8.7089 21.4727 -0.9305 19.8355
Caki-1 GDSC1; CTRP2 9.1717 15.4569 3.6185 5.4743
UO-31 GDSC1; CTRP2 9.2501 20.6214 1.2238 13.842
VMRC-RCZ GDSC1; CTRP2 9.5081 15.0469 3.9968 3.7777
SNU-1272 CTRP2 10.6985 20.7161 2.129 8.9423
ACHN GDSC1; CTRP2 12.4003 23.014 2.0882 7.264
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1040 GDSC1 4.8983 6.5227 3.6569 3.4878
GP5d GDSC1 5.9941 8.629 3.3506 3.3159
SW1116 GDSC1 6.0036 8.2564 3.5164 2.2705
LoVo GDSC1; CTRP2 6.1297 9.1862 4.544 6.144
SW837 GDSC1 6.1673 8.1191 3.6523 1.3099
SNU-175 GDSC1 6.3336 9.503 3.1535 3.9761
COLO 320HSR GDSC1 6.3936 7.9368 3.8169 0.4481
CW-2 GDSC1; CTRP2 6.5235 10.3223 4.2905 6.4964
HCT 8 CTRP2 6.5851 7.8613 4.6217 0.2822
SNU-C1 GDSC1 6.7391 8.2776 3.8256 0.2729
MDST8 GDSC1; CTRP2 6.7665 9.3238 4.9605 3.3364
SW626 GDSC1 6.8982 9.4613 3.451 1.5181
HT115 GDSC1; CTRP2 6.9612 8.4107 5.5097 0.9777
NCI-H508 CTRP2 7.0268 8.4868 5.5121 0.9091
NCI-H747 GDSC1; CTRP2 7.0526 17.2953 1.2355 17.3658
SNU-81 GDSC1; CTRP2 7.1585 11.1185 4.3651 5.1747
LS123 GDSC1; CTRP2 7.2818 10.8629 4.572 4.1681
CL-11 GDSC1; CTRP2 7.3605 9.5156 5.244 1.5174
RKO GDSC1; CTRP2 7.3658 9.6815 5.1733 1.7629
HCC2998 GDSC1 7.4063 9.3683 3.689 0.3473
HCC-56 CTRP2 7.4234 8.3789 5.734 0.119
SNU-407 GDSC1; CTRP2 7.4296 9.2935 5.3773 1.0086
COLO205 GDSC1; CTRP2 7.4618 10.2656 4.9654 2.42
LS1034 GDSC1; CTRP2 7.4717 9.0614 5.4942 0.6277
SW48 GDSC1; CTRP2 7.5012 9.3064 5.408 0.8584
SW948 GDSC1; CTRP2 7.5057 8.8066 5.6094 0.3209
SNU-C2B GDSC1 7.5906 10.1943 3.4635 0.9095
CaR-1 GDSC1 7.6846 16.6475 0.6858 15.488
HT-55 GDSC1; CTRP2 7.6858 9.0797 5.5812 0.3065
SNU-61 GDSC1; CTRP2 7.7359 10.195 5.1515 1.4865
DLD-1 CTRP2 7.7972 9.0678 5.6298 0.1816
NCI-H716 GDSC1; CTRP2 7.8063 9.608 5.4295 0.6027
OUMS-23 CTRP2 7.8545 9.0632 5.653 0.134
SK-CO-1 CTRP2 7.8911 9.357 5.5613 0.2707
HT-29 GDSC1; CTRP2 7.9445 9.2436 5.6228 0.1553
LS513 GDSC1; CTRP2 7.9761 9.3378 5.6012 0.179
SNU-1033 CTRP2 7.9769 12.9019 4.0613 5.2524
SNU-503 CTRP2 7.9872 9.4796 5.5544 0.2519
COLO 320 CTRP2 7.9951 10.3594 5.2141 1.0836
C2BBe1 GDSC1; CTRP2 8.0127 10.2896 5.2513 0.9628
KM12 GDSC1; CTRP2 8.0185 9.4334 5.5832 0.1955
T84 GDSC1; CTRP2 8.0457 10.0019 5.3815 0.5955
SW1417 GDSC1; CTRP2 8.067 9.5532 5.5587 0.2211
HCT 15 GDSC1; CTRP2 8.0774 9.947 5.4165 0.4973
LS411N GDSC1; CTRP2 8.0827 9.4853 5.589 0.171
SNU-C4 CTRP2 8.1037 9.2614 5.6739 0.0698
SW1463 GDSC1; CTRP2 8.1641 9.725 5.5342 0.2336
GP2d CTRP2 8.1739 9.6744 5.5561 0.1969
COLO 678 GDSC1; CTRP2 8.2029 9.6521 5.5748 0.1635
HCT 116 GDSC1; CTRP2 8.2333 9.6045 5.6025 0.1228
COLO201 CTRP2 8.2663 9.5269 5.6408 0.0787
LS180 GDSC1; CTRP2 8.3663 10.0125 5.5084 0.2201
RCM-1 [Human ESC] GDSC1; CTRP2 8.3978 9.6702 5.6381 0.0657
SNU-C5 GDSC1; CTRP2 8.4133 10.2417 5.4438 0.3127
CCK-81 GDSC1; CTRP2 8.6088 10.1704 5.5422 0.1266
SW620 GDSC1; CTRP2 8.6126 10.1821 5.5395 0.1289
SNU-C2A CTRP2 8.6531 13.1901 4.3402 3.4221
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 6.2085 18.9136 -1.4675 27.2482
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Huh-7 GDSC1 6.2378 8.6351 3.4752 2.1719
Hep-G2/C3A GDSC1 6.4569 7.8286 3.8791 0.2512
Hep 3B2.1-7 GDSC1; CTRP2 6.5443 8.9878 4.9657 3.6557
HLE GDSC1 6.6863 8.6326 3.6778 0.7419
SNU-761 CTRP2 6.6866 8.4173 4.4509 0.6588
SNU-878 CTRP2 6.7139 9.8273 4.6777 4.574
JHH-7 GDSC1 6.8912 8.3328 3.8607 0.1618
HuH-6 CTRP2 6.9142 11.6265 3.9409 7.2894
SNU-182 CTRP2 6.9539 13.6331 2.9788 11.1262
SNU-398 GDSC1; CTRP2 7.1151 11.0077 4.3885 5.1438
JHH-5 CTRP2 7.13 9.9487 4.9058 3.0512
JHH-6 GDSC1; CTRP2 7.3094 7.9657 5.8352 0.0286
SNU-475 GDSC1; CTRP2 7.4331 10.2261 4.9662 2.4492
JHH-2 GDSC1; CTRP2 7.5042 9.5449 5.3089 1.1676
SNU-423 GDSC1; CTRP2 7.5541 9.7638 5.2411 1.348
SK-HEP-1 GDSC1; CTRP2 7.5613 9.5702 5.3275 1.0612
HuH-1 GDSC1; CTRP2 7.6621 9.2042 5.5237 0.4447
SNU-886 CTRP2 7.7015 15.8617 2.4389 11.9643
HLF CTRP2 7.8859 9.5425 5.4897 0.4187
SNU-387 GDSC1; CTRP2 8.0536 10.0932 5.3492 0.6721
Hep-G2 CTRP2 8.1423 9.4409 5.6263 0.1115
PLC/PRF/5 CTRP2 8.1725 12.5053 4.368 3.8415
Li-7 CTRP2 8.3941 10.41 5.3737 0.4547
SNU-449 GDSC1; CTRP2 8.4567 11.7258 4.8729 1.7877
JHH-1 GDSC1; CTRP2 10.9803 19.5509 2.8259 6.3024
JHH-4 GDSC1; CTRP2 12.5098 27.0474 0.3175 12.3972
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 214 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H847 GDSC1 4.7888 6.7036 3.4942 5.0184
NCI-H2347 GDSC1 4.9816 14.7886 -0.3723 27.2111
NCI-H1688 GDSC1 5.2858 7.3186 3.5303 3.4942
COR-L311 GDSC1 5.5449 9.8085 2.5189 10.1459
NCI-H1648 GDSC1 5.5656 8.4127 3.1968 5.2384
NCI-H82 GDSC1 5.636 7.5499 3.6268 2.1759
NCI-H2135 GDSC1 5.8141 7.3536 3.7958 0.9836
NCI-H1975 GDSC1 5.8165 9.0806 3.0427 5.7561
NCI-H345 GDSC1 5.8267 6.7156 4.0366 0.1211
NCI-H64 GDSC1 5.9027 8.02 3.5648 2.134
NCI-H2373 GDSC1 5.9172 8.9408 3.1676 4.6773
ABC-1 GDSC1 5.9649 9.6706 2.8613 6.6825
NCI-H1876 GDSC1 5.9844 7.8649 3.6695 1.433
NCI-H513 GDSC1 6.0025 8.2314 3.5264 2.213
NCI-H1304 GDSC1 6.0046 7.6013 3.7832 0.8552
NCI-H1734 GDSC1; CTRP2 6.0678 8.6171 4.7775 5.2802
COR-L303 GDSC1 6.1429 11.9785 1.8844 12.7315
NCI-H510A GDSC1 6.1766 8.4362 3.5277 1.9591
NCI-H720 GDSC1 6.1857 7.58 3.8655 0.4098
NCI-H1781 GDSC1 6.2013 8.0782 3.6838 1.1217
NCI-H2810 GDSC1 6.2184 8.8455 3.3766 2.7799
NCI-H1770 GDSC1 6.2187 7.5493 3.8891 0.3233
NCI-H2818 GDSC1 6.2419 8.6625 3.4659 2.2195
NCI-H2444 GDSC1; CTRP2 6.2801 8.9984 3.9778 2.769
NCI-H1651 GDSC1 6.3461 8.0246 3.7659 0.652
COR-L23 GDSC1 6.3524 8.0611 3.7549 0.689
Lu-139 GDSC1 6.3673 16.1289 0.0241 21.6617
NCI-H1836 GDSC1 6.3731 7.8409 3.8436 0.3786
Lu-165 GDSC1 6.3785 7.7955 3.8617 0.3256
NCI-H1436 GDSC1 6.4236 8.0618 3.7832 0.5402
NCI-H226 GDSC1; CTRP2 6.449 7.5793 4.6713 0.2319
NCI-H1993 GDSC1 6.4498 8.1315 3.768 0.5757
HCC33 GDSC1 6.4582 7.7862 3.8942 0.2172
NCI-H2722 GDSC1 6.4712 8.3697 3.6879 0.8622
NCI-H2869 GDSC1 6.4833 9.233 3.3479 2.5554
NCI-H187 GDSC1 6.4883 7.7577 3.9147 0.1679
EBC-1 GDSC1; CTRP2 6.4917 9.7258 4.5619 5.4195
NCI-H1341 GDSC1; CTRP2 6.4926 7.603 5.5995 1.1613
UMC-11 GDSC1 6.5449 8.3042 3.7424 0.6046
NCI-H2795 GDSC1 6.567 14.1637 1.1231 15.9868
IST-SL1 GDSC1 6.5773 8.6755 3.6161 1.0748
NCI-H146 GDSC1 6.5785 8.6776 3.6158 1.0749
NCI-H1694 GDSC1; CTRP2 6.6008 8.2789 5.3499 2.0036
NCI-H1184 CTRP2 6.6129 11.7315 3.6596 8.9598
Ms-1 GDSC1 6.6179 7.9993 3.878 0.2013
LXF 289 GDSC1; CTRP2 6.6336 10.8436 4.1164 7.0319
SBC-3 GDSC1 6.6368 8.4079 3.7407 0.5546
COR-L321 GDSC1 6.6425 8.3 3.7818 0.4253
NCI-H446 GDSC1; CTRP2 6.6464 10.9891 4.0541 7.2686
NCI-H290 GDSC1 6.6499 8.1721 3.8298 0.2956
LK-2 GDSC1 6.6502 8.1001 3.8549 0.2386
NCI-H322M GDSC1 6.6572 10.4355 2.922 4.8665
NCI-H2369 GDSC1 6.6742 8.3076 3.7911 0.3844
NCI-H2803 GDSC1 6.6754 8.3023 3.7935 0.3776
EKVX GDSC1; CTRP2 6.6999 10.5412 3.5227 4.089
NCI-H2085 CTRP2 6.7093 12.8982 3.1546 10.8508
LCLC-97TM1 GDSC1; CTRP2 6.713 9.8432 4.6693 4.6101
NCI-H2804 GDSC1 6.7248 9.4146 3.3903 2.0078
CPC-N GDSC1 6.7278 8.6372 3.6927 0.6611
Calu-3 GDSC1; CTRP2 6.7708 9.5634 4.8474 3.7906
NCI-H596 GDSC1 6.7947 8.3973 3.8042 0.3022
RERF-LC-Ad1 CTRP2 6.7997 11.4885 3.9233 7.5509
SBC-1 GDSC1 6.8243 8.3418 3.834 0.2275
NCI-H1092 GDSC1; CTRP2 6.8256 8.4354 5.4202 1.4442
NCI-H1573 GDSC1; CTRP2 6.8388 8.5111 5.3934 1.5297
NCI-H2066 GDSC1 6.8491 9.247 3.5129 1.2833
NCI-H2595 GDSC1 6.871 8.7997 3.6898 0.5854
RERF-LC-KJ GDSC1 6.872 8.4946 3.7985 0.2876
NCI-H1568 GDSC1; CTRP2 6.8732 8.7181 5.319 1.7717
NCI-H1437 GDSC1 6.8793 8.6105 3.7606 0.3762
SK-MES-1 GDSC1; CTRP2 6.8831 8.8174 5.2789 1.9132
HCC95 CTRP2 6.8836 15.8612 1.8166 26.8002
EMC-BAC-2 GDSC1 6.8935 8.7694 3.7094 0.5125
NCI-H1666 GDSC1; CTRP2 6.8979 10.4804 4.4911 5.0537
LB647-SCLC GDSC1 6.9129 8.797 3.7069 0.5098
HOP-62 GDSC1; CTRP2 6.9166 10.4367 4.5259 4.8827
PC-14 GDSC1; CTRP2 6.9196 8.9503 4.3449 0.8149
HCC44 GDSC1; CTRP2 6.9235 14.2957 2.6265 12.5617
SK-LU-1 GDSC1; CTRP2 6.9352 10.3536 4.5795 4.6358
HCC2935 CTRP2 6.9407 10.0117 4.7489 3.9391
NCI-H1155 GDSC1; CTRP2 6.9804 9.5985 4.9738 2.9816
NCI-H889 CTRP2 6.9935 10.721 4.4421 5.1081
NCI-H1339 CTRP2 6.9965 9.3757 5.0896 2.5047
NCI-H2731 GDSC1 7.0012 9.2639 3.5706 0.9203
NCI-H524 GDSC1 7.0091 8.6365 3.7988 0.2428
EPLC-272H GDSC1; CTRP2 7.0217 11.2876 4.1859 6.1121
NCI-H835 GDSC1 7.0334 9.0682 3.6556 0.6033
Lu-99A GDSC1 7.0474 10.0076 3.3018 2.086
LC-1F CTRP2 7.091 11.6109 4.0778 6.4462
NCI-H2228 GDSC1; CTRP2 7.0931 9.7331 4.1071 1.4322
NCI-H209 GDSC1 7.1003 9.0971 3.6709 0.5219
SBC-5 GDSC1; CTRP2 7.1354 7.899 5.796 0.0982
NCI-H3255 GDSC1 7.1377 9.2579 3.6274 0.6346
SW1573 GDSC1 7.1575 11.7773 2.608 5.9142
BEN GDSC1; CTRP2 7.165 8.2176 5.6898 0.2938
NCI-H1838 GDSC1; CTRP2 7.1653 9.2591 5.2472 1.7066
LK2 CTRP2 7.1772 8.1055 5.7373 0.1864
HCC15 GDSC1; CTRP2 7.1866 9.5632 5.1212 2.1511
NCI-H2461 GDSC1 7.2123 12.1964 2.4527 6.7597
NCI-H1581 GDSC1; CTRP2 7.2246 9.0014 5.395 1.1256
NCI-H1048 GDSC1 7.2321 8.8684 3.7983 0.1851
NCI-H1355 GDSC1; CTRP2 7.2352 9.3122 5.2638 1.5731
NCI-H211 GDSC1; CTRP2 7.2923 9.5427 5.1932 1.7677
NCI-H2591 GDSC1 7.3216 9.6934 3.5407 0.8125
NCI-H2087 GDSC1; CTRP2 7.3318 12.5121 3.8105 7.1615
LC-2/ad GDSC1 7.341 9.233 3.7122 0.3183
Lu-134-A GDSC1 7.3508 9.0948 3.7631 0.216
NCI-H1693 CTRP2 7.3545 10.0522 4.9985 2.4185
COR-L95 GDSC1; CTRP2 7.362 8.6334 5.6144 0.3764
NCI-H1915 GDSC1; CTRP2 7.4088 9.2449 5.3872 0.9937
NCI-H3122 GDSC1 7.4089 9.3602 3.6927 0.3381
NCI-H292 GDSC1; CTRP2 7.449 9.2518 5.4048 0.9071
Lu-135 GDSC1 7.4495 9.134 3.7841 0.1607
NCI-H841 GDSC1; CTRP2 7.4509 10.6262 4.7926 3.0859
DMS 273 GDSC1; CTRP2 7.4883 9.3354 5.3895 0.9245
SW1271 GDSC1; CTRP2 7.4998 13.0622 2.8502 5.7812
HCC1195 CTRP2 7.5164 10.6347 4.8291 2.8686
MOR/CPR CTRP2 7.5177 8.3512 5.7776 0.0514
HCC2279 CTRP2 7.519 14.0765 3.1812 9.391
NCI-H1703 GDSC1; CTRP2 7.5275 11.1641 4.5898 3.7735
NCI-H1299 GDSC1; CTRP2 7.5338 9.5261 5.3321 1.0685
HOP-92 CTRP2 7.5365 15.8944 1.5296 11.0045
NCI-H1435 GDSC1; CTRP2 7.547 9.4809 5.3579 0.9775
NCI-H2023 GDSC1; CTRP2 7.5663 9.837 5.2159 1.4213
NCI-H1755 GDSC1; CTRP2 7.5664 12.9701 3.7533 7.0396
DMS 53 GDSC1; CTRP2 7.5697 10.6268 4.865 2.672
NCI-H23 GDSC1; CTRP2 7.602 9.6612 5.3098 1.0849
LCLC-103H GDSC1; CTRP2 7.6135 8.8473 5.6383 0.222
EMC-BAC-1 GDSC1 7.6194 10.2232 3.4644 0.8883
HCC366 CTRP2 7.6293 10.0334 5.1645 1.5381
NCI-H1385 CTRP2 7.6717 10.823 4.8365 2.6638
NCI-H460 GDSC1; CTRP2 7.6976 8.7937 5.6896 0.1187
NCI-H1792 GDSC1; CTRP2 7.6997 11.631 4.4806 3.9796
RERF-LC-Sq1 GDSC1 7.7171 10.077 3.5549 0.557
LOU-NH91 GDSC1; CTRP2 7.7255 10.0126 5.2242 1.2579
NCI-H2196 GDSC1; CTRP2 7.7777 9.8342 5.325 0.9089
A-427 GDSC1 7.8033 9.6447 3.7345 0.1632
NCI-H838 GDSC1; CTRP2 7.8203 8.9875 5.6669 0.1229
LUDLU-1 CTRP2 7.8238 9.687 5.4061 0.6537
HCC1833 CTRP2 7.8487 11.3204 4.7152 2.916
NCI-H810 GDSC1; CTRP2 7.8633 9.0695 5.654 0.1307
NCI-H647 GDSC1; CTRP2 7.8721 9.7424 5.4061 0.6265
Lu-99 CTRP2 7.878 9.3019 5.5764 0.2477
A-549 GDSC1; CTRP2 7.8888 9.7014 5.4296 0.5582
NCI-H69 GDSC1; CTRP2 7.9085 9.7112 5.4345 0.5363
NCI-H727 GDSC1; CTRP2 7.9175 10.179 5.2508 1.0297
NCI-H520 GDSC1; CTRP2 7.9223 10.7597 5.0067 1.806
COLO 668 GDSC1; CTRP2 7.928 9.4142 5.555 0.27
NCI-H2141 GDSC1; CTRP2 7.9331 9.2401 5.6198 0.1622
LC-1/sq-SF CTRP2 7.9402 9.1966 5.6378 0.1359
NCI-H2171 GDSC1; CTRP2 7.9527 9.0973 5.6767 0.0879
NCI-H1944 GDSC1; CTRP2 7.9652 10.2421 5.248 1.0048
IA-LM GDSC1; CTRP2 7.9733 9.283 5.6196 0.1532
RERF-LC-Ad2 CTRP2 7.9825 9.6539 5.4879 0.3818
NCI-H2122 GDSC1; CTRP2 7.9978 9.3784 5.595 0.1828
Sq-1 CTRP2 8.0023 9.4294 5.5785 0.2073
NCI-H1563 GDSC1; CTRP2 8.009 9.3625 5.6049 0.1657
COR-L88 GDSC1; CTRP2 8.0222 9.4586 5.5756 0.2065
PaCa-3 GDSC1 8.0223 16.0012 1.2023 12.2146
NCI-H2126 CTRP2 8.028 9.0603 5.7153 0.0456
NCI-H358 GDSC1; CTRP2 8.0286 14.8038 3.1877 8.5924
NCI-H196 GDSC1; CTRP2 8.0719 12.5549 4.2836 4.278
HCC827 GDSC1; CTRP2 8.0754 11.9896 4.5453 3.2923
NCI-H2405 GDSC1; CTRP2 8.0767 11.2727 4.8666 2.1414
NCI-H2172 GDSC1; CTRP2 8.1154 9.608 5.5576 0.2097
NCI-H526 GDSC1; CTRP2 8.1243 9.4234 5.6259 0.1152
NCI-H2009 GDSC1; CTRP2 8.1288 9.7406 5.5148 0.2771
SHP-77 GDSC1; CTRP2 8.1373 9.6061 5.5666 0.1904
NCI-H2029 GDSC1; CTRP2 8.1385 9.5551 5.5851 0.1637
NCI-H1373 CTRP2 8.1743 11.3346 4.8925 1.9638
NCI-H2291 GDSC1; CTRP2 8.1967 15.6646 2.8884 9.4974
DV-90 CTRP2 8.1979 9.7794 5.5276 0.2348
NCI-H1793 GDSC1; CTRP2 8.2016 13.8111 3.7781 6.058
Calu-6 GDSC1; CTRP2 8.2018 10.0049 5.4465 0.3809
IST-SL2 GDSC1 8.2093 18.7218 0.0469 17.1748
Lu-65 GDSC1; CTRP2 8.2379 9.6622 5.5842 0.144
NCI-H1105 GDSC1; CTRP2 8.2621 9.9247 5.5 0.262
HCC1171 CTRP2 8.2658 15.3778 3.0741 8.6881
HCC78 GDSC1; CTRP2 8.2753 13.9411 3.7645 6.0145
NCI-H2106 CTRP2 8.293 9.895 5.5225 0.2174
NCI-H1869 GDSC1; CTRP2 8.3026 10.4686 5.3124 0.6331
RERF-LC-A1 CTRP2 8.3036 11.8491 4.7383 2.3692
NCI-H2081 GDSC1; CTRP2 8.3244 9.6682 5.6132 0.0968
HCC1588 CTRP2 8.3953 9.641 5.647 0.0593
COR-L105 GDSC1; CTRP2 8.4057 10.3722 5.3926 0.4116
NCI-H322 CTRP2 8.4111 11.3701 4.9995 1.4277
NCI-H441 GDSC1; CTRP2 8.4267 9.865 5.5821 0.1131
DMS 454 CTRP2 8.4351 10.8835 5.2086 0.8216
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 8.4475 10.0623 5.5211 0.1827
CAL-12T GDSC1; CTRP2 8.471 10.1697 5.4919 0.2185
KNS-62 GDSC1; CTRP2 8.4846 10.3489 5.4327 0.31
VMRC-LCD CTRP2 8.4944 9.8803 5.6007 0.0855
T3M-10 CTRP2 8.5036 10.2053 5.4915 0.2112
NCI-H2170 GDSC1; CTRP2 8.5146 9.9718 5.5768 0.1053
HCC4006 CTRP2 8.5482 9.8422 5.632 0.0555
COR-L51 CTRP2 8.5936 10.4969 5.4215 0.2964
NCI-H650 GDSC1; CTRP2 8.5999 10.0502 5.5801 0.0906
NCI-H522 GDSC1; CTRP2 8.6008 10.2087 5.5261 0.146
NCI-H2342 GDSC1; CTRP2 8.6404 10.4586 5.453 0.2343
ChaGo-K-1 GDSC1; CTRP2 8.6849 10.4168 5.4843 0.1811
NCI-H2110 GDSC1; CTRP2 8.7536 10.539 5.4668 0.1896
HCC2108 CTRP2 8.8149 16.4024 2.9524 8.3878
RERF-LC-MS GDSC1; CTRP2 8.9535 15.9681 3.2468 7.1098
NCI-H1623 GDSC1; CTRP2 9.0249 10.8802 5.4468 0.1625
HCC1438 CTRP2 9.0607 17.3566 2.6614 9.1317
NCI-H2286 CTRP2 9.4337 18.2065 2.5028 9.2111
NCI-H1395 CTRP2 9.4883 11.5417 5.385 0.1543
NCI-H1650 GDSC1; CTRP2 9.5327 16.6896 3.2715 6.3204
NCI-H661 GDSC1; CTRP2 9.9049 17.4242 3.159 6.301
COLO 699 CTRP2 10.0598 18.9908 2.533 8.3217
DMS 114 GDSC1; CTRP2 10.723 19.2436 1.9322 5.5853
NCI-H2030 GDSC1; CTRP2 11.2378 21.9604 1.8852 9.1227
Calu-1 CTRP2 12.597 24.1995 0.7875 7.455
Hs 888.Lu CTRP2 6.9512 9.4121 5.043 2.7469
⏷ Show the Full List of 214 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 6.9822 14.1305 1.4181 13.3622
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.7054 7.9041 5.5905 0.9472
P-STS CTRP2 8.0146 9.3682 5.6049 0.1643
SYO-1 CTRP2 8.549 9.8601 5.6263 0.0593
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.2393 9.3877 5.2323 1.6822
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 7.6745 9.0411 5.5911 0.2909
Aska-SS CTRP2 7.7693 8.9018 5.6781 0.1188
EW-8 GDSC1 5.6431 8.4774 3.2148 4.9355
VA-ES-BJ GDSC1 6.319 7.847 3.8205 0.4786
SW872 GDSC1 6.6344 8.482 3.7126 0.6512
Hs 633.T GDSC1 6.7484 17.8424 -0.5382 22.8508
HT-1080 GDSC1; CTRP2 6.7817 8.2252 5.49 1.2334
Rh30 GDSC1 6.8918 8.651 3.751 0.396
MFH-ino GDSC1 6.9045 8.6878 3.7427 0.4125
BT-12 CTRP2 6.9202 11.0739 4.2169 6.1445
RKN GDSC1; CTRP2 6.9295 8.0903 5.6309 0.604
TE 617.T CTRP2 7.0076 8.585 5.4586 1.1107
SK-LMS-1 GDSC1; CTRP2 7.2861 10.7112 4.647 3.8647
Rh41 GDSC1; CTRP2 7.4317 10.3513 4.9079 2.6699
MES-SA GDSC1; CTRP2 7.4328 11.6198 4.3117 4.9968
G-402 GDSC1; CTRP2 7.5074 10.6726 4.8061 2.9663
Hs 729.T CTRP2 7.5976 9.5518 5.3536 0.9526
BT-16 CTRP2 7.6018 8.8944 5.6162 0.2682
TE 441.T CTRP2 7.6237 8.9521 5.6036 0.2851
RD GDSC1; CTRP2 7.7128 9.5392 5.4141 0.6983
Tm87-16 CTRP2 7.845 9.553 5.4682 0.4872
SW982 GDSC1; CTRP2 7.8921 9.0993 5.6541 0.1246
TTC-709 CTRP2 7.9246 9.288 5.5995 0.195
G-401 GDSC1; CTRP2 7.9334 10.8272 4.9832 1.8753
KYM-1 GDSC1; CTRP2 8.1234 10.2522 5.3177 0.7141
SW684 GDSC1 8.5968 19.7651 -0.1938 17.3426
Rh18 GDSC1; CTRP2 8.5987 16.537 2.7439 9.4631
SK-UT-1 GDSC1; CTRP2 8.7278 10.2631 5.5526 0.099
A-204 GDSC1; CTRP2 8.8132 15.9772 3.1525 7.6421
GCT GDSC1; CTRP2 11.6618 23.9848 1.2113 10.756
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.9123 10.0994 5.281 0.9447
OVCAR-3 GDSC1 4.7758 10.8541 1.426 19.6572
TOV-21G GDSC1 6.0224 7.3499 3.8853 0.4395
Caov-4 GDSC1 6.0492 8.2461 3.5438 2.0438
JHOS-4 GDSC1 6.2283 8.3711 3.5793 1.6138
ES-2 GDSC1 6.3764 7.8737 3.8331 0.4079
OVKATE GDSC1 6.5943 8.4219 3.7188 0.6555
SNU-119 CTRP2 6.8107 10.4015 4.4668 5.2897
FU-OV-1 GDSC1; CTRP2 7.0664 13.3624 3.1983 10.0587
OAW42 GDSC1; CTRP2 7.1505 9.0832 5.3178 1.4665
IGROV-1 GDSC1; CTRP2 7.2378 9.5055 5.1783 1.8808
JHOS-2 GDSC1; CTRP2 7.3152 9.1202 5.3919 1.0563
COV644 CTRP2 7.3352 10.0737 4.9769 2.5223
OV56 GDSC1; CTRP2 7.3839 8.699 5.5984 0.4041
TOV-112D GDSC1; CTRP2 7.5343 9.2667 5.4405 0.7392
TYK-nu GDSC1; CTRP2 7.6588 9.4713 5.4163 0.7262
ES2 CTRP2 7.6972 8.7769 5.6954 0.1114
OV-90 GDSC1; CTRP2 7.7301 15.6961 2.5411 11.5334
SNU-840 CTRP2 7.7326 10.3075 5.101 1.6593
OVCAR-8 GDSC1; CTRP2 7.7516 9.7419 5.3502 0.8533
OAW28 GDSC1; CTRP2 7.7974 11.7247 4.4983 3.7913
ONCO-DG-1 CTRP2 7.8027 10.1185 5.2189 1.213
RMG-I GDSC1; CTRP2 7.8111 12.0403 4.3598 4.3067
SNU-8 CTRP2 7.899 9.0271 5.6816 0.0911
Caov-3 GDSC1; CTRP2 7.9118 12.4068 4.2522 4.5959
HEY A8 CTRP2 7.9173 10.7241 5.0194 1.7673
SK-OV-3 GDSC1; CTRP2 7.9555 9.706 5.4568 0.4614
DOV13 GDSC1; CTRP2 7.9785 9.775 5.4402 0.4888
OVTOKO GDSC1; CTRP2 7.9834 13.573 3.7476 6.4688
OVK18 GDSC1; CTRP2 7.9873 9.6761 5.4815 0.3933
OVISE GDSC1; CTRP2 8.0026 9.193 5.6616 0.0959
OC 314 GDSC1; CTRP2 8.0184 9.3291 5.6201 0.1426
JHOC-5 CTRP2 8.0859 9.5044 5.5834 0.1784
MCAS CTRP2 8.1858 9.6785 5.5591 0.1895
COV434 CTRP2 8.2008 10.8094 5.1287 1.1918
JHOM-1 CTRP2 8.2399 9.6874 5.5761 0.1539
OV7 CTRP2 8.2654 9.6212 5.6083 0.1109
COV362 CTRP2 8.309 9.794 5.5642 0.1552
A2780 GDSC1; CTRP2 8.4795 14.905 3.442 6.9849
OVCAR-4 GDSC1; CTRP2 8.6996 11.1069 5.2375 0.6197
Kuramochi GDSC1; CTRP2 8.7416 15.7028 3.2355 7.424
EFO-27 GDSC1; CTRP2 8.7546 15.6704 3.2592 7.3179
EFO-21 GDSC1; CTRP2 9.4216 15.9383 3.5481 5.4493
OVCAR-5 GDSC1; CTRP2 10.7151 19.2761 2.7965 6.676
OVSAHO CTRP2 11.2845 26.5267 -0.2278 15.3703
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1; CTRP2 6.6628 13.2837 2.1833 9.7785
MSTO-211H GDSC1; CTRP2 6.6818 10.532 4.3071 6.1592
IST-Mes1 GDSC1; CTRP2 7.3795 12.1809 4.005 6.3046
MPP 89 GDSC1; CTRP2 7.4199 9.1352 5.439 0.8242
JL-1 CTRP2 7.5446 10.0338 5.1177 1.78
NCI-H2052 GDSC1; CTRP2 7.8202 13.3387 3.75 6.6865
ACC-MESO-1 CTRP2 7.884 9.2738 5.5889 0.2239
NCI-H28 GDSC1; CTRP2 8.3558 9.982 5.5153 0.2124
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 5.5639 10.6223 2.1372 12.7041
LNCaP clone FGC GDSC1; CTRP2 6.2106 8.1622 5.1206 3.574
VCaP GDSC1; CTRP2 7.4494 9.1009 5.4676 0.7182
22Rv1 GDSC1; CTRP2 7.7567 11.5363 4.5604 3.6034
DU145 GDSC1; CTRP2 7.9372 10.3023 5.2093 1.14
PaCa-3 CTRP2 11.9051 20.7605 2.8056 5.4859
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 7.1085 9.7381 4.9911 2.7454
A-253 GDSC1; CTRP2 7.5876 11.0828 4.6657 3.4057
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 6.291 7.9906 3.756 0.7299
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1 5.0505 7.2639 3.4049 4.9785
GCIY GDSC1 5.7067 8.4121 3.2832 4.3212
TGBC11TKB GDSC1 6.3708 8.3723 3.6437 1.1415
RF-48 GDSC1 6.5172 8.3496 3.7144 0.7239
LMSU CTRP2 6.5709 9.1744 4.8936 3.911
SCH GDSC1 6.6799 8.5825 3.6938 0.6883
GSS CTRP2 6.723 8.4274 5.3598 1.8012
SNU-601 CTRP2 6.9838 8.5766 4.5174 0.3447
Hs 746.T GDSC1; CTRP2 7.0027 9.5547 5.0092 2.8118
GSU CTRP2 7.0741 7.7254 5.8344 0.0603
SNU-216 CTRP2 7.1322 10.0111 4.0094 1.7301
SNU-16 GDSC1; CTRP2 7.1366 8.5868 5.5267 0.7691
OCUM-1 GDSC1; CTRP2 7.1408 11.2705 4.2791 5.5498
MKN45 GDSC1; CTRP2 7.2101 8.3925 5.6414 0.389
SNU-5 GDSC1; CTRP2 7.2495 8.6718 5.5472 0.623
RERF-GC-1B GDSC1 7.3075 9.7527 3.5131 0.9194
SNU-620 CTRP2 7.3242 8.5851 5.6166 0.3904
SNU-668 CTRP2 7.3434 10.3046 4.875 2.9009
MKN28 GDSC1 7.4965 9.2852 3.7494 0.204
23132/87 GDSC1; CTRP2 7.5235 9.277 5.431 0.774
NUGC-3 GDSC1; CTRP2 7.716 10.3007 5.0949 1.6951
SNU-1 GDSC1; CTRP2 7.8772 9.5339 5.4893 0.4235
ECC12 CTRP2 7.8888 9.0526 5.6692 0.1068
MKN74 CTRP2 7.9217 9.9779 5.3348 0.7869
IM95 GDSC1; CTRP2 8.024 10.0387 5.3574 0.6675
HGC-27 GDSC1; CTRP2 8.0773 10.5731 5.1659 1.1688
MKN1 GDSC1; CTRP2 8.0834 9.5209 5.5766 0.189
NUGC-4 GDSC1; CTRP2 8.2108 10.5066 5.2564 0.8246
SH-10-TC CTRP2 8.3023 9.5543 5.644 0.0715
AGS GDSC1; CTRP2 8.3147 9.5908 5.636 0.0769
NCI-N87 GDSC1; CTRP2 8.4316 10.8894 5.2047 0.8336
KE-39 CTRP2 8.4382 11.2084 5.0794 1.1723
HuG1-N CTRP2 8.49 10.347 5.4355 0.3035
ECC10 GDSC1; CTRP2 8.5531 10.0466 5.5648 0.1116
MKN7 GDSC1; CTRP2 8.5822 10.5531 5.3965 0.3429
SNU-719 CTRP2 8.7928 10.3587 5.5429 0.0993
KATO III GDSC1; CTRP2 9.0805 21.3222 0.7641 15.5483
Fu97 GDSC1; CTRP2 11.1253 25.4862 0.162 14.4984
SNU-1077 CTRP2 7.3845 9.6035 5.2186 1.5831
SNU-685 CTRP2 7.5149 9.0139 5.5331 0.4982
SNG-M GDSC1; CTRP2 7.8695 11.517 4.638 3.179
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 5.5181 7.1635 3.7306 1.7258
KMH-2 GDSC1 6.2795 7.9081 3.7822 0.638
WRO GDSC1 6.4383 8.1908 3.7415 0.6782
TT2609-C02 GDSC1; CTRP2 6.6862 8.5506 5.2773 2.1756
SW579 CTRP2 6.7418 8.5999 5.2907 2.0477
BHT-101 GDSC1; CTRP2 6.7473 8.6821 5.2552 2.1804
K5 GDSC1 6.7496 8.2834 3.8274 0.2654
CAL-62 GDSC1; CTRP2 6.8263 8.6022 5.3435 1.7346
ML-1 [Human leukemia] GDSC1; CTRP2 6.8936 8.8969 4.3544 0.8043
FTC-238 CTRP2 7.0063 8.4264 5.5273 0.8764
ASH-3 GDSC1 7.0469 8.4328 3.8806 0.1041
CGTH-W-1 GDSC1; CTRP2 7.4544 9.012 5.5061 0.6056
HTC-C3 GDSC1 7.4721 18.4399 -0.3154 20.2673
8505C GDSC1; CTRP2 7.551 11.1884 4.5934 3.7299
TT GDSC1; CTRP2 7.6811 10.0267 5.195 1.39
FTC-133 GDSC1; CTRP2 7.839 8.9548 5.685 0.0974
B-CPAP GDSC1; CTRP2 7.8466 9.4752 5.4987 0.4161
8305C GDSC1; CTRP2 8.0332 15.1537 3.0219 9.2273
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-15 GDSC1 4.5355 6.5906 3.3603 6.843
KON GDSC1 5.8537 7.8 3.6327 1.8081
SKN-3 GDSC1 6.0375 8.3403 3.4982 2.3279
OSC-19 GDSC1 6.2214 7.822 3.7906 0.6477
HO-1-u-1 GDSC1 6.3997 8.342 3.6681 1.0058
BICR 78 GDSC1 6.4184 8.4366 3.6396 1.1153
DOK GDSC1 6.4334 12.7877 1.6931 13.1382
NCI-H3118 GDSC1 6.4836 9.0131 3.4392 2.0456
BICR 10 GDSC1 6.5824 8.3135 3.7538 0.5435
SAS GDSC1 6.6265 9.1116 3.4665 1.7307
BB30-HNC GDSC1 6.6838 8.2253 3.8236 0.2975
PCI-38 GDSC1 6.6849 8.2741 3.8069 0.3382
PCI-15A GDSC1 6.7197 8.1376 3.8668 0.194
PCI-30 GDSC1 6.7541 8.3217 3.8157 0.2902
JHU-011 GDSC1 6.7943 8.9314 3.6102 0.9209
SCC-25 GDSC1; CTRP2 6.8061 9.9373 4.6904 4.3784
YD-10B CTRP2 6.8652 9.0465 5.1599 2.3999
SNU-46 CTRP2 6.8711 9.5782 4.91 3.389
BB49-HNC GDSC1 6.8752 9.0813 3.5873 0.9496
OSC-20 GDSC1 6.9024 8.786 3.7068 0.5155
PCI-06A GDSC1 6.9805 8.6729 3.7759 0.3004
HO-1-N-1 GDSC1 6.9868 8.5087 3.8345 0.1828
YD-8 CTRP2 7.1365 10.8403 4.4843 4.7247
HSC-4 GDSC1; CTRP2 7.2165 9.6659 5.0922 2.2257
HSC-3 GDSC1; CTRP2 7.2426 10.5192 4.7095 3.6759
CAL-27 GDSC1; CTRP2 7.2567 10.3085 4.8182 3.2301
LB771-HNC GDSC1 7.2679 9.3084 3.659 0.4764
BHY GDSC1; CTRP2 7.2692 9.1685 5.3463 1.2501
PE/CA-PJ34 (clone C12) CTRP2 7.2737 9.951 4.9957 2.5237
BICR 16 CTRP2 7.2813 11.5247 3.4241 3.7615
Ca9-22 GDSC1 7.2846 9.2857 3.6732 0.4318
HSC-2 GDSC1; CTRP2 7.312 10.3672 4.826 3.1293
PE/CA-PJ49 CTRP2 7.3261 8.7236 5.5625 0.5303
Detroit 562 GDSC1; CTRP2 7.351 10.0529 4.9961 2.4316
PCI-04B GDSC1 7.3708 9.6282 3.5837 0.6437
BICR 31 GDSC1; CTRP2 7.3716 9.6507 5.1903 1.6961
JHU-022 GDSC1 7.3798 9.0938 3.7735 0.1916
BICR 22 GDSC1; CTRP2 7.3937 9.3104 5.3515 1.1217
KOSC-2 GDSC1 7.4138 9.3385 3.702 0.3163
SAT [Human HNSCC] GDSC1 7.4536 9.5352 3.648 0.4265
SNU-1214 CTRP2 7.519 10.3419 4.9647 2.359
SNU-899 CTRP2 7.6161 10.4702 4.9635 2.2583
BICR 56 CTRP2 7.8067 15.5832 1.8611 9.3085
CAL-33 GDSC1; CTRP2 7.9097 9.65 5.4587 0.4784
PE/CA-PJ41 (clone D2) CTRP2 7.9551 9.4338 5.5585 0.2548
FaDu GDSC1; CTRP2 8.0471 9.7515 5.4779 0.3768
BICR 18 CTRP2 8.0626 9.6426 5.5246 0.2809
SCC-4 GDSC1; CTRP2 8.1578 9.624 5.5679 0.1834
BICR 6 CTRP2 8.2044 9.3372 5.6831 0.0516
SNU-1076 CTRP2 8.2876 13.1934 4.1214 4.6343
PE/CA-PJ15 GDSC1; CTRP2 8.4184 9.9523 5.549 0.1526
SCC-9 GDSC1; CTRP2 8.4582 10.3764 5.4122 0.3553
SNU-1066 CTRP2 8.6823 10.0595 5.6053 0.0616
SNU-1041 CTRP2 8.8216 10.5922 5.4731 0.1684
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC1 6.0943 7.8198 3.7375 0.9772
SW780 GDSC1 6.4329 7.9943 3.8114 0.444
JMSU-1 CTRP2 6.5711 9.484 4.7414 4.5405
BC-3C CTRP2 6.7185 10.7084 4.2476 6.3448
253J CTRP2 6.7375 10.5098 4.3597 5.8494
253J-BV CTRP2 6.9582 8.7262 5.3668 1.4932
SW1710 GDSC1; CTRP2 7.1879 10.9462 4.4686 4.7139
647V GDSC1; CTRP2 7.3558 8.921 5.4962 0.6989
SCaBER CTRP2 7.392 8.9023 5.5212 0.6032
TCCSUP GDSC1; CTRP2 7.481 10.2018 5.0058 2.2492
639V GDSC1; CTRP2 7.5888 8.837 5.6322 0.2417
T24 GDSC1; CTRP2 7.648 9.6734 5.3279 0.9935
BFTC-905 GDSC1; CTRP2 7.7019 8.8957 5.6551 0.1674
UM-UC-1 CTRP2 7.7984 11.8736 4.4296 4.0535
KU-19-19 GDSC1; CTRP2 7.8098 8.8006 5.7274 0.0593
VM-CUB-1 CTRP2 7.8958 11.9178 4.4697 3.7818
HT-1197 GDSC1; CTRP2 7.9084 12.5084 4.2024 4.7928
UM-UC-3 GDSC1; CTRP2 8.0744 14.0148 3.5976 6.9305
J82 GDSC1; CTRP2 8.0799 10.2954 5.2806 0.8378
RT-4 GDSC1; CTRP2 8.1807 9.866 5.4894 0.3061
HT-1376 GDSC1; CTRP2 8.3349 10.1513 5.4459 0.3345
RT-112 GDSC1; CTRP2 8.5589 9.9651 5.5945 0.083
5637 GDSC1; CTRP2 8.5737 14.0532 3.9002 5.1267
KMBC-2 CTRP2 10.0731 19.0613 2.5085 8.3908
U-BLC1 CTRP2 10.4403 21.6206 1.5443 11.1833
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JAR GDSC1 5.2239 7.5209 3.3972 4.5981
C-4-I GDSC1 5.2343 16.1456 -0.8478 28.0431
KGN GDSC1 5.5778 10.6264 2.1451 12.6114
HT-3 GDSC1 5.6743 7.8703 3.5077 2.8709
SKN GDSC1 5.9087 8.455 3.38 3.2782
SW756 GDSC1 6.0121 7.4031 3.8616 0.5299
JHOS-3 GDSC1 6.0551 10.3123 2.6185 8.1424
SiSo GDSC1 6.1113 8.6629 3.3988 2.8141
OMC-1 [Human cervical carcinoma] GDSC1 6.1566 7.9189 3.7263 0.9694
SKG-IIIa GDSC1 6.1756 7.5172 3.8842 0.3581
SW962 GDSC1 6.3712 13.2653 1.4214 14.87
HEC-1 GDSC1 6.3829 7.6166 3.9256 0.1765
PWR-1E GDSC1 6.4343 9.3896 3.2566 3.1671
ACC-OV7 GDSC1 6.4404 9.485 3.2189 3.3868
TC-YIK GDSC1 6.4496 8.2619 3.7195 0.7532
OVMIU GDSC1 6.5097 8.7574 3.5543 1.4235
NEC8 GDSC1 6.5376 8.411 3.6998 0.7646
LB831-BLC GDSC1 6.5583 8.7699 3.5711 1.2944
PA-1 GDSC1 6.5871 8.1407 3.8176 0.3519
JEG-3 GDSC1 6.6299 8.2322 3.8012 0.3769
C-33 A GDSC1 6.6582 10.0287 3.0999 3.7596
DoTc2 4510 GDSC1 6.6787 8.5344 3.711 0.6288
UWB1.289 GDSC1 6.8042 16.2529 0.2772 19.4509
PEO1 GDSC1 6.8066 8.714 3.6957 0.603
SW954 GDSC1 6.824 14.4259 1.1723 15.0768
Ca Ski GDSC1 6.8337 9.6664 3.3396 2.1424
NT2-D1 GDSC1 6.8989 8.4851 3.8114 0.2507
CAL-39 GDSC1 6.916 8.9743 3.6437 0.7122
DSH1 GDSC1 6.9319 8.4397 3.8387 0.1892
OVCA433 GDSC1 6.9631 9.2092 3.5755 0.9296
OVCA420 GDSC1 6.9645 8.6576 3.7754 0.3072
MS751 GDSC1 6.9847 8.7353 3.7557 0.3461
NCC-IT GDSC1 7.0796 8.5818 3.842 0.1501
BPH-1 GDSC1 7.0916 12.3388 2.3188 7.8149
OV17R GDSC1 7.1229 15.6177 0.8033 16.2252
HeLa GDSC1; CTRP2 7.2046 8.7688 5.4844 0.8487
ME-180 GDSC1 7.4476 10.1512 3.4215 1.1655
HEY GDSC1 7.4676 9.4367 3.6875 0.3299
SiHa GDSC1 9.2749 21.7482 -0.6902 17.8792
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Selective role of PI3K delta in neutrophil inflammatory responses. Biochem Biophys Res Commun. 2003 Sep 5;308(4):764-9.
2 Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation. Cancer Res. 2009 Feb 1;69(3):1027-36. doi: 10.1158/0008-5472.CAN-08-2608. Epub 2009 Jan 27.