Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMZ43OM)

• Drug Name: PMID26560530-Compound-25 Drug Info
• Cross-matching ID:
  PubChem CID: 2194
  ChEBI ID: CHEMBL31221
  CAS Number: CAS 532-11-6
  TTD Drug ID: D0C2QU

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Base excision repair	2.05	0.00e+0	29/33 (87.88%)	PCNA;FEN1;TDG;...
DNA replication	1.85	3.14e-2	34/36 (94.44%)	PCNA;FEN1;RFC3;...
Nucleotide excision repair	1.83	2.79e-2	40/47 (85.11%)	PCNA;CETN2;RFC3;...
Mismatch repair	1.82	2.09e-2	22/23 (95.65%)	PCNA;RFC3;MSH6;...
Protein digestion and absorption	-1.96	2.89e-2	78/103 (75.73%)	MEP1B;COL16A1;CELA3A;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Liver

Hepatocellular carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HuH-7	CVCL_0336	Homo sapiens	15uM	72H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Show ▼