Details of the Drug Reposition

General Information of This Drug (ID: DM74LZK)

Drug Name
Cromoglicate   DM74LZK
Synonyms Crolom (TN); Intal (TN); Nasalcrom (TN); Opticrom (TN); Optrex Allergy (TN); Prevalin (TN); Rynacrom (TN)
Therapeutic Class
Antiasthmatic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
2 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Vernal keratoconjunctivitis DIS36LV6 N.A. Approved [1]
Asthma DISW9QNS CA23 Approved [2]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Allergic conjunctivitis DISZ5ZJN 9A60.02 Withdrawn [3]
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2 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Vernal conjunctivitis DISSQWNO N.A. Discontinued in Phase 2 [4]
Systemic mastocytosis DISNQ2OY 2A21.0 Discontinued in Phase 2 [5]
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1 Terminated Indication(s)
Indication Name Indication ID ICD-11 Status REF
Allergic rhinitis DIS3U9HN CA08.0 Terminated [6]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Giant papillary conjunctivitis DISVLIOB N.A. Investigative [7]
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References

1 Twenty-first century mast cell stabilizers. Br J Pharmacol. 2013 Sep;170(1):23-37.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7608).
3 A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
4 Ketoconazole as Inhibitor of the Enzyme CYP17 in Locally Advanced or Disseminated Granulosa Cell Tumour of Ovary
5 ClinicalTrials.gov (NCT00257699) Study of Antibiotics in the Treatment of Colonic Crohn's Disease
6 Sodium cromoglicate: an ineffective drug or meta-analysis misused Pharm Stat. 2007 Apr-Jun;6(2):123-37.
7 Diagnostics and new developments in the treatment of ocular allergies. Curr Allergy Asthma Rep. 2012 Jun;12(3):232-9.