Details of the Drug Reposition

General Information of This Drug (ID: DMUI0CH)

Drug Name
Tobramycin   DMUI0CH
Synonyms
Aktob; Brulamycin; Distobram; Gotabiotic; NEBRAMYCIN; Nebcin; Nebicin; Obracin; Obramycin; Sybryx; TOY; Tenebrimycin;Tenemycin; Tobacin; Tobi; Tobracin; Tobradex; Tobradistin; Tobralex; Tobramaxin; Tobramicin; Tobramicina; Tobramitsetin; Tobramycetin; Tobramycine; Tobramycinum; Tobrased; Tobrasone; Tobrex; Deoxykanamycin B; Nebramycin VI; TOBRAMYCIN SULFATE; Tobramycin for Inhalation; Tobramycin solution for inhalation; A 12253A; Lilly 47663; NF 6; Nebramycin 6; Nebramycin factir 6; Nebramycin factor 6; Nebcin (Sulfate); SPRC-AB01; TobraDex (TN); Tobracin (TN); Tobramicina [INN-Spanish]; Tobramycin, Free Base; Tobramycine [INN-French]; Tobramycinum [INN-Latin]; Tobrex (TN); Tobramycin (JP15/USP); Tobramycin[USAN:BAN:INN:JAN]; TOA-(1-6)2TB-(4-1)TOC; TOA-(1-6)TOB-(4-1)TOC; 1-Epitobramycin; 3'-Deoxykanamycin B
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
11 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Staphylococcus aureus infection DISK6PTH N.A. Approved [1]
Staphylococcal pneumonia DIS28ZSZ N.A. Approved [1]
Peritonitis DISMCMLQ N.A. Approved [1]
Neonatal sepsis DIS8Q3VE N.A. Approved [1]
Dacryocystitis DISFBZLV N.A. Approved [1]
Blepharoconjunctivitis DIS4PG4J N.A. Approved [1]
Bacterial infection DIS5QJ9S 1A00-1C4Z Approved [2]
Bacteremia DIS6N9RZ 1A73 Approved [1]
Demodex blepharitis DISDSJDZ 1G07 Approved [1]
Rosacea DIS02PWG ED90.0 Approved [1]
Corneal abrasion DIS3SD7J NA06.4 Approved [1]
------------------------------------------------------------------------------------
⏷ Show the Full List of 11 Indications(s)
1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Allergic conjunctivitis DISZ5ZJN 9A60.02 Withdrawn [3]
------------------------------------------------------------------------------------
4 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Bacterial meningitis DISRP9SL N.A. Discontinued in Phase 3 [4]
Keratoconjunctivitis DISOYCQC N.A. Discontinued in Phase 3 [5]
Anterior uveitis DISQ7EAD 9A96 Discontinued in Phase 3 [6]
Bacterial pneumonia DISPW7PH CA40.0 Discontinued in Phase 3 [7]
------------------------------------------------------------------------------------
3 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Rhinoscleroma DISNSWVK N.A. Discontinued in Phase 2 [8]
Bacterial conjunctivitis DIST79FU N.A. Discontinued in Phase 2 [9]
Escherichia coli infection DISPP65M 1A03 Discontinued in Phase 2 [10]
------------------------------------------------------------------------------------

References

1 Tobramycin FDA Label
2 How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73.
3 GRN1005 for Brain Metastases From Breast or Lung Cancer
4 Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache
5 "Efficacy and Safety of Levofloxacin vs Isoniazid in Latent Tuberculosis Infection in Liver Transplant Patients".
6 Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide
7 Combination Therapy for the Treatment of Bipolar Disorders
8 Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)
9 Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma
10 Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial