Details of the Drug

General Information of Drug (ID: DM19FS3)

Drug Name
Norzimelidine
Synonyms
Norzimeldine; 3-(4-Bromophenyl)-N-methyl-3-(3-pyridinyl)-2-propen-1-amine; 2-Propen-1-amine, 3-(4-bromophenyl)-N-methyl-3-(3-pyridinyl)-; cholesterol-3-glucose; AC1O5OK9; CHEMBL173745; SCHEMBL11636758; 60324-58-5; LS-175771; A-23889; 3-(4-bromophenyl)-N-methyl-(3-pyiidyl)allylamine oxalate
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 303.2
Logarithm of the Partition Coefficient (xlogp) 3.4
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C15H15BrN2
IUPAC Name
(Z)-3-(4-bromophenyl)-N-methyl-3-pyridin-3-ylprop-2-en-1-amine
Canonical SMILES
CNC/C=C(/C1=CC=C(C=C1)Br)\\C2=CN=CC=C2
InChI
InChI=1S/C15H15BrN2/c1-17-10-8-15(13-3-2-9-18-11-13)12-4-6-14(16)7-5-12/h2-9,11,17H,10H2,1H3/b15-8-
InChIKey
AZFZKANGXPSDEA-NVNXTCNLSA-N
Cross-matching ID
PubChem CID
5378630
CAS Number
60324-59-6
TTD ID
D0A0KE
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine uptake (MA uptake) TTJXYQ6 NOUNIPROTAC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 The antidepressant agents desipramine, fluoxetine, fluvoxamine and norzimelidine inhibit uptake of [3H]noradrenaline and [3H]5-hydroxytryptamine in slices of human and rat cortical brain tissue. Brain Res. 1983 Sep 19;275(1):99-104.