Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTJXYQ6)

DTT Name Monoamine uptake (MA uptake)
Synonyms Monoamine(MA) uptake
Gene Name MA uptake
DTT Type
Literature-reported target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T69141

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desmethylclomipramine DMIESYM Discovery agent N.A. Investigative [2]
Norzimelidine DM19FS3 N. A. N. A. Investigative [1]
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References

1 The antidepressant agents desipramine, fluoxetine, fluvoxamine and norzimelidine inhibit uptake of [3H]noradrenaline and [3H]5-hydroxytryptamine in slices of human and rat cortical brain tissue. Brain Res. 1983 Sep 19;275(1):99-104.
2 Do alpha2-adrenoceptors play an integral role in the antinociceptive mechanism of action of antidepressant compounds Eur J Pharmacol. 1999 Aug 6;378(2):161-8.