Details of the Drug

General Information of Drug (ID: DM1AQLW)

Drug Name
Otilimab
Synonyms Otilimab [USAN]; UNII-Y8127R3VCH; Y8127R3VCH; MOR103; GSK3196165; 1638332-55-4; human monoclonal antibody
Indication
Disease Entry ICD 11 Status REF
Rheumatoid arthritis FA20 Phase 3 [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [2]
Therapeutic Class
Antiviral Agents
Drug Type
Monoclonal antibody
Cross-matching ID
UNII
Y8127R3VCH
DrugBank ID
DB06303
TTD ID
D04GWO
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HUMAN colony-stimulating factor (GM-CSF) TTPZGYX CSF2_HUMAN Inhibitor [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04333147) Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA). U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT04376684) Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease. U.S. National Institutes of Health.
3 The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19. J Autoimmun. 2020 Apr 17:102468.