Details of the Drug

General Information of Drug (ID: DM1FW0C)

Drug Name
AZD7762
Synonyms
AZD7762; 860352-01-8; AZD-7762; (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide; AZD 7762; UNII-5D822Y3L1H; 3-(Carbamoylamino)-5-(3-Fluorophenyl)-N-[(3s)-Piperidin-3-Yl]thiophene-2-Carboxamide; CHEMBL2041933; 5D822Y3L1H; J-502468; 5-(3-Fluorophenyl)-N-[(3s)-3-Piperidyl]-3-Ureido-Thiophene-2-Carboxamide; IAYGCINLNONXHY-LBPRGKRZSA-N; YDJ; AZD7762 hydrochloride; 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide; SCHEMBL1127614; GTPL7713; AOB1915; QCR-261; CHEBI:131156
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 362.4
Logarithm of the Partition Coefficient (xlogp) 2.3
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H19FN4O2S
IUPAC Name
3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
Canonical SMILES
C1C[C@@H](CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
InChI
InChI=1S/C17H19FN4O2S/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24)/t12-/m0/s1
InChIKey
IAYGCINLNONXHY-LBPRGKRZSA-N
Cross-matching ID
PubChem CID
11152667
ChEBI ID
CHEBI:131156
CAS Number
860352-01-8
UNII
5D822Y3L1H
DrugBank ID
DB12242
TTD ID
D0PM7Q
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Checkpoint kinase-1 (CHK1) TTTU902 CHK1_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Serine/threonine-protein kinase Chk2 (CHEK2) OT8ZPCNS CHK2_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Checkpoint kinase-1 (CHK1) DTT CHEK1 7.22E-191 1.43 4.74
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -1.4718 1.977 -1.6132 46.6999
ES4 GDSC1; GDSC2 -3.7561 0.5178 -3.8557 65.8042
SK-PN-DW GDSC1; GDSC2 -2.9914 -0.1249 -3.0119 60.6918
EW-12 GDSC2 -2.9456 -1.2036 -2.9564 36.0319
ES7 GDSC1; GDSC2 -2.8952 0.4633 -2.9466 59.5066
EW-7 GDSC1; GDSC2 -2.7318 -0.4526 -2.7378 58.5156
ES8 GDSC1; GDSC2 -2.4999 0.4357 -2.5337 56.1291
ES1 GDSC1; GDSC2 -2.3121 0.24 -2.3301 54.4734
EW-1 GDSC1; GDSC2 -2.2176 -0.3704 -2.2199 53.6513
A-673 GDSC1; GDSC2; CTRP2 -2.1994 2.3161 -2.2725 54.6676
NOS-1 [Human HNSCC] GDSC1; GDSC2 -2.1678 2.8021 -2.5357 52.5935
TC-71 GDSC1; GDSC2 -2.1522 0.5011 -2.1779 52.9501
U2OS GDSC1; GDSC2; CTRP2 -1.9222 0.5181 -1.9239 49.7621
EW-22 GDSC1; GDSC2 -1.7988 1.705 -1.9224 49.6396
Hs 888.T CTRP2 -1.7126 4.3583 -2.0275 51.4698
SK-N-MC CTRP2 -1.6755 0.2257 -1.6757 51.4307
ES5 GDSC1; GDSC2 -1.4335 0.8602 -1.4552 35.8698
HuO9 GDSC1; GDSC2 -1.3871 3.9761 -2.0097 46.5686
TC71 CTRP2 -1.3249 -0.8911 -1.3249 49.0954
HOS GDSC1; GDSC2; CTRP2 -1.3084 1.0761 -1.3109 48.9877
SJSA-1 GDSC1; GDSC2; CTRP2 -1.1892 3.4661 -1.3243 48.2934
CAL-72 GDSC1; GDSC2 -1.1777 2.7638 -1.4483 44.2893
CHSA0108 GDSC1; GDSC2 -0.982 3.3461 -1.3817 33.8184
SK-ES-1 GDSC1; GDSC2; CTRP2 -0.8058 1.3442 -0.8076 45.6416
MHH-ES-1 GDSC1; GDSC2; CTRP2 -0.7937 2.101 -0.8083 42.7509
NY GDSC1; GDSC2 -0.7892 3.2216 -1.1377 41.0186
EW-11 GDSC1; GDSC2 -0.7209 3.1766 -1.0513 40.3506
CHSA0011 GDSC1; GDSC2 -0.6225 8.4594 -2.983 36.7336
H-EMC-SS GDSC1; GDSC2 -0.5674 8.6074 -2.9938 43.2638
CAL-78 GDSC1; GDSC2; CTRP2 -0.5088 4.4575 -0.7449 44.1125
SaOS-2 GDSC1; GDSC2; CTRP2 -0.3601 2.8655 -0.397 42.7635
HuO-3N1 GDSC1; GDSC2 -0.2375 5.8009 -1.4378 38.7469
EW-18 GDSC1; GDSC2 -0.151 2.8886 -0.3592 34.5979
ES6 GDSC1; GDSC2 -0.0639 4.0779 -0.6041 35.1511
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 0.1715 2.9331 0.1483 39.1979
EW-16 GDSC1; GDSC2 0.1981 4.3279 -0.4066 33.0365
MG-63 GDSC1; GDSC2; CTRP2 0.4243 5.3497 0.0858 38.3873
EW-3 GDSC1; GDSC2 0.4385 5.3641 -0.5478 32.4612
SW1353 CTRP2 0.5654 3.8587 0.4898 36.7394
CHSA8926 GDSC1; GDSC2 0.9833 7.9306 -1.1357 32.2508
EW-24 GDSC1; GDSC2 1.0481 4.6406 0.3876 25.4348
CADO-ES1 GDSC1; GDSC2 1.1064 3.1207 0.9558 22.2225
EW-13 GDSC1; GDSC2 1.9347 4.4578 1.3968 16.3432
U-CH2 GDSC2 2.5119 5.1609 0.0035 2.7599
Hs 822.T CTRP2 3.5227 8.5808 2.3438 21.1571
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 221 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -5.0522 0.1118 -5.0937 71.3533
MEC1 CTRP2 -3.3248 0.4434 -3.3393 62.049
JM1 GDSC1; GDSC2; CTRP2 -2.3279 -0.5742 -2.3279 52.2957
MV4-11 GDSC1; GDSC2; CTRP2 -11.7908 -4.426 -11.8234 92.114
MOLM-13 GDSC1; GDSC2; CTRP2 -11.6865 -5.6036 -11.6956 94.1667
EoL-1 GDSC1; GDSC2; CTRP2 -10.9261 -8.2708 -10.9261 98.5491
NKM-1 GDSC1; GDSC2 -9.257 -3.9959 -9.282 92.4885
SEM CTRP2 -8.9899 -1.9417 -9.0485 85.4631
Kasumi-1 GDSC1; GDSC2; CTRP2 -7.4624 -4.3612 -7.4626 82.9858
Mono-Mac-6 GDSC1; GDSC2; CTRP2 -7.0735 -0.1786 -7.1681 78.587
Pfeiffer CTRP2 -6.8513 -2.6245 -6.856 82.2434
PL21 CTRP2 -6.4963 -3.8205 -6.4964 82.5452
Mono-Mac-1 CTRP2 -6.2342 7.747 -7.8565 66.2953
Hs 611.T CTRP2 -5.6296 -2.8984 -5.6298 77.2275
SU-DHL-5 GDSC1; GDSC2 -5.1825 -2.7248 -5.1836 80.4493
JeKo-1 GDSC1; GDSC2; CTRP2 -4.9078 -3.2169 -4.9078 68.4042
NU-DUL-1 GDSC1; GDSC2; CTRP2 -4.8925 -2.6099 -4.8926 68.2665
SU-DHL-6 GDSC1; GDSC2; CTRP2 -4.8207 -2.5701 -4.8208 72.267
Ri-1 CTRP2 -4.6881 -0.6997 -4.6979 70.4392
ATN-1 GDSC1; GDSC2 -4.6203 -3.8981 -4.6203 76.9432
SUP-T11 CTRP2 -4.6021 -1.2428 -4.605 70.3679
MOLM-6 CTRP2 -4.5901 -0.0905 -4.6127 69.4016
WSU-NHL GDSC1; GDSC2 -4.5394 -2.6511 -4.5396 75.7004
JURL-MK1 GDSC1; CTRP2 -4.5101 -2.4853 -4.5101 70.2672
Karpas-231 GDSC1; GDSC2 -4.4163 -2.3947 -4.4167 74.4486
M-07e CTRP2 -4.3117 -2.1406 -4.3118 68.9352
AML-193 CTRP2 -4.269 -1.5608 -4.2696 68.5317
KE-37 GDSC1; GDSC2; CTRP2 -4.206 -3.0204 -4.206 68.2893
DEL GDSC1; GDSC2; CTRP2 -4.1478 -2.6191 -4.1478 67.8972
NB4 GDSC1; GDSC2 -4.1131 -2.8003 -4.1131 55.9572
GDM-1 GDSC1; GDSC2; CTRP2 -4.07 2.9139 -4.3234 64.1325
MLMA GDSC1; GDSC2 -4.0577 0.6314 -4.188 67.4907
ALL-PO GDSC1; GDSC2 -3.9272 2.1055 -4.2934 64.5467
MHH-PREB-1 GDSC1; GDSC2 -3.7698 -1.0781 -3.7772 67.9209
BL-41 GDSC1; GDSC2 -3.7099 -2.2724 -3.7099 68.0836
RCH-ACV GDSC1; GDSC2; CTRP2 -3.6734 -2.0578 -3.6734 60.6994
SET-2 CTRP2 -3.5877 0.0641 -3.5978 63.7768
Karpas-299 GDSC1; GDSC2; CTRP2 -3.57 -2.0084 -3.57 64.0504
CTV-1 GDSC1; GDSC2 -3.5692 -2.7788 -3.5692 66.7616
SUP-M2 GDSC1; GDSC2 -3.5665 -2.2139 -3.5665 66.7134
L-363 GDSC1; GDSC2; CTRP2 -3.4587 -2.3667 -3.4587 63.3108
SU-DHL-8 GDSC1; GDSC2; CTRP2 -3.4455 2.0577 -3.5564 61.8498
OCI-Ly7 GDSC1; GDSC2 -3.4109 -2.0963 -3.411 50.6728
JVM-2 GDSC1; GDSC2; CTRP2 -3.4095 -0.6615 -3.4108 62.8898
A4/Fukuda GDSC1; GDSC2; CTRP2 -3.3485 -0.5642 -3.35 62.4821
697 GDSC1; GDSC2; CTRP2 -3.3477 -1.7026 -3.3477 62.5686
RPMI-8866 GDSC1 -3.322 -1.5393 -3.3224 64.285
PL-21 GDSC1; GDSC2 -3.3102 -0.8117 -3.3169 49.9153
GA-10 GDSC1; GDSC2; CTRP2 -3.2919 -0.2449 -3.2952 62.0573
TK [Human B-cell lymphoma] GDSC1; GDSC2 -3.2764 -1.0591 -3.2793 63.6986
P31/FUJ GDSC1; GDSC2; CTRP2 -3.2715 -2.0246 -3.2715 62.0636
Ki-JK CTRP2 -3.2654 -2.3315 -3.2654 62.0234
BONNA-12 GDSC2 -3.2519 -0.5664 -3.3251 39.0699
WIL2 NS GDSC1; GDSC2 -3.2207 -1.8866 -3.2207 63.3738
OCI-Ly10 CTRP2 -3.1926 0.9946 -3.2223 61.0383
SU-DHL-16 GDSC1; GDSC2 -3.1905 -1.9717 -3.1905 49.0138
DND-41 GDSC1; GDSC2; CTRP2 -3.1396 -0.7763 -3.14 61.1548
CML-T1 GDSC1; GDSC2; CTRP2 -3.1348 -1.5721 -3.1348 61.1521
P32/ISH GDSC1; GDSC2 -3.1267 -0.4142 -3.1399 62.0311
NALM-6 GDSC1; GDSC2; CTRP2 -3.0954 -0.8439 -3.0957 60.8696
BV-173 GDSC1; GDSC2; CTRP2 -3.0951 -0.6616 -3.0956 60.8536
KMS-26 CTRP2 -3.0896 -1.9547 -3.0896 60.8518
EM-2 GDSC1; GDSC2; CTRP2 -3.0792 -1.8151 -3.0792 60.7826
DoHH2 GDSC1; GDSC2; CTRP2 -3.0734 -1.7149 -3.0734 56.9526
EB1 CTRP2 -3.0652 1.7215 -3.1308 59.9733
Ku812 GDSC1; GDSC2; CTRP2 -3.0383 -0.3044 -3.0399 60.4452
MOLT-16 GDSC1; GDSC2; CTRP2 -3.0233 -2.104 -3.0233 60.4106
SR GDSC1; GDSC2; CTRP2 -2.9853 -1.6855 -2.9853 60.157
JVM-3 GDSC1; GDSC2; CTRP2 -2.9847 -0.5235 -2.9855 60.1201
Peer CTRP2 -2.9429 -1.4696 -2.9429 59.8744
SKM-1 GDSC1; GDSC2 -2.9394 -1.0895 -2.9404 47.1263
GR-ST GDSC1; GDSC2 -2.9352 0.3128 -2.9775 59.9387
MHH-CALL-2 GDSC1; GDSC2 -2.9321 -1.1365 -2.9329 60.539
OCI-AML-2 GDSC1; GDSC2; CTRP2 -2.9251 -2.1487 -2.9251 59.7561
KHM-1B CTRP2 -2.9161 -0.9086 -2.9162 59.6885
RPMI-8402 GDSC1; GDSC2; CTRP2 -2.9098 -1.8514 -2.9098 59.654
Namalwa GDSC1; GDSC2; CTRP2 -2.9086 -0.5885 -2.9091 59.6253
ALL-SIL GDSC1; GDSC2; CTRP2 -2.9046 -1.5698 -2.9046 59.619
CTB-1 GDSC1; GDSC2 -2.9005 0.4606 -2.952 46.9133
KMS-12-BM GDSC1; GDSC2; CTRP2 -2.8871 -1.8845 -2.8871 59.5029
LAMA-84 GDSC1; GDSC2; CTRP2 -2.8493 -1.27 -2.8493 59.2498
OCI-AML-5 GDSC1; CTRP2 -2.8439 0.86 -2.8611 58.9792
MEG-01 GDSC1; GDSC2 -2.8403 -0.5367 -2.8461 59.5383
BDCM CTRP2 -2.8297 2.6228 -2.9648 58.2378
CCRF-CEM GDSC1; GDSC2 -2.8098 -1.2602 -2.8101 59.3884
NOMO-1 GDSC1; GDSC2; CTRP2 -2.7757 -0.8096 -2.7758 58.7553
MOLM-16 GDSC1; GDSC2; CTRP2 -2.7621 -1.3722 -2.7621 55.0084
QIMR-WIL GDSC1; GDSC2 -2.7617 -0.1657 -2.7754 45.8181
Kasumi-2 CTRP2 -2.7588 -0.0733 -2.7606 58.6036
Farage GDSC1; GDSC2 -2.7395 -0.6444 -2.7428 45.6278
Ramos.2G6.4C10 GDSC1; GDSC2 -2.7235 -0.7576 -2.7256 58.5062
HAL-01 GDSC1; GDSC2 -2.7212 0.6368 -2.7788 57.9539
BALL-1 GDSC1; GDSC2 -2.7146 -0.6996 -2.7172 58.4124
NU-DHL-1 CTRP2 -2.7117 1.9515 -2.7791 57.8371
Jiyoye GDSC1; GDSC2 -2.708 -1.7792 -2.708 58.4181
CRO-AP2 GDSC1; GDSC2 -2.6961 -0.6468 -2.6991 45.3011
KCL-22 GDSC1; GDSC2; CTRP2 -2.6808 -1.6481 -2.6808 58.1287
NCO2 CTRP2 -2.6766 -1.1356 -2.6766 58.0999
JSC-1 GDSC1; GDSC2 -2.6729 0.1605 -2.6974 57.7692
L-540 GDSC1; GDSC2; CTRP2 -2.6688 -0.853 -2.6688 58.0459
P12-Ichikawa GDSC1; GDSC2; CTRP2 -2.6653 -0.8439 -2.6653 58.0225
KE-97 CTRP2 -2.655 -1.6935 -2.655 57.9566
A3/Kawakami GDSC1; GDSC2; CTRP2 -2.601 -0.5952 -2.6011 57.5915
HuT 78 CTRP2 -2.5824 -0.5988 -2.5825 57.4683
KMS-34 CTRP2 -2.5656 -1.5677 -2.5656 57.3608
H9 GDSC1; GDSC2 -2.5509 -1.0932 -2.5511 56.89
SUP-B8 GDSC1; GDSC2 -2.5408 3.9706 -3.2645 45.2624
HPB-ALL CTRP2 -2.533 -0.7017 -2.533 57.1414
ML-2 GDSC1; GDSC2 -2.5213 -1.0441 -2.5215 56.6026
P30/OHK GDSC1; GDSC2 -2.5026 -0.79 -2.5035 56.4098
Karpas-1106P GDSC1; GDSC2 -2.48 1.6791 -2.6489 55.4351
U-937 CTRP2 -2.404 -1.8747 -2.404 56.2843
SIG-M5 GDSC2; CTRP2 -2.3881 -1.3107 -2.3881 52.672
KYO-1 CTRP2 -2.3567 -1.2777 -2.3567 55.9695
EJM GDSC1; GDSC2; CTRP2 -2.3038 0.0444 -2.3047 55.606
OCI-Ly19 GDSC1; GDSC2; CTRP2 -2.3029 1.6 -2.335 52.093
Hs 445 GDSC1; GDSC2 -2.2682 0.0684 -2.2792 55.98
SCC-3 GDSC2 -2.2622 -0.853 -2.2624 56.0311
RPMI-8226 GDSC1; GDSC2; CTRP2 -2.2478 0.4879 -2.251 55.2171
VAL GDSC1; GDSC2 -2.2373 3.7534 -2.8681 52.8456
MOTN-1 CTRP2 -2.2318 0.9916 -2.2421 55.0728
BE-13 GDSC1; GDSC2 -2.2265 -0.798 -2.2268 53.7511
KMS-21-BM CTRP2 -2.2259 -0.7284 -2.2259 55.0974
ARH-77 GDSC1; GDSC2 -2.2029 -0.0735 -2.2094 53.4906
KOPN-8 GDSC1; GDSC2 -2.1862 -0.1348 -2.1913 53.3357
MOLT-4 GDSC1; GDSC2 -2.1464 -0.6368 -2.1469 52.9746
Daudi GDSC1; GDSC2; CTRP2 -2.1381 0.6749 -2.1424 54.4865
MOLP-2 CTRP2 -2.1211 4.4237 -2.4824 53.74
EB2 GDSC1; GDSC2 -2.0956 0.5982 -2.1248 52.4124
U-698-M GDSC1; GDSC2 -2.0862 -0.076 -2.0911 52.3771
Mino CTRP2 -2.0802 -1.1522 -2.0802 54.1273
HEL GDSC1; GDSC2; CTRP2 -2.0788 -0.8971 -2.0788 50.7401
NK-92MI GDSC2 -2.0739 -0.8344 -2.0787 28.0556
HD-MY-Z CTRP2 -2.0492 -0.6123 -2.0492 53.9209
WSU-DLCL2 GDSC1; GDSC2; CTRP2 -2.0476 -0.6317 -2.0476 53.9101
KMS-11 GDSC1; GDSC2; CTRP2 -2.0063 0.5721 -2.0087 50.2866
KMS-28BM CTRP2 -1.9915 6.8949 -2.9717 52.5784
P3HR-1 CTRP2 -1.9814 3.4789 -2.1707 53.1441
MOLP-8 GDSC1; GDSC2; CTRP2 -1.9563 0.5337 -1.9582 53.2925
F-36P CTRP2 -1.9445 0.0179 -1.9447 53.2215
MOLT-3 CTRP2 -1.9232 -1.1572 -1.9232 53.0815
OCI-M1 GDSC1; GDSC2; CTRP2 -1.8927 -1.0715 -1.8927 52.8783
HuNS1 CTRP2 -1.8872 0.025 -1.8874 52.8403
AMO1 GDSC1; GDSC2; CTRP2 -1.88 -0.3089 -1.88 52.793
RS4;11 GDSC1; GDSC2; CTRP2 -1.8717 0.9491 -1.8771 52.7223
RPMI-6666 GDSC1; GDSC2; CTRP2 -1.8653 2.0027 -1.9042 52.6198
TUR GDSC1; GDSC2 -1.8607 -0.7559 -1.8607 50.2097
HEL 92.1.7 CTRP2 -1.8191 -1.0355 -1.8191 52.3879
CESS GDSC1; GDSC2 -1.8078 0.9067 -1.8461 49.7065
Granta-519 GDSC1; GDSC2; CTRP2 -1.794 1.65 -1.8149 52.1833
Karpas-45 GDSC1; GDSC2 -1.7812 -0.1388 -1.7828 49.4405
BC-3 GDSC2 -1.7715 -0.13 -1.8072 25.4406
SU-DHL-1 GDSC2; CTRP2 -1.7676 -0.0718 -1.7677 48.7965
MOLT-13 GDSC1; GDSC2; CTRP2 -1.7592 -0.1168 -1.7593 51.9888
Ci-1 CTRP2 -1.7131 -0.9272 -1.7131 51.6816
OCI-Ly3 CTRP2 -1.6824 0.4758 -1.6832 51.4757
Jurkat GDSC1; GDSC2; CTRP2 -1.6641 -0.3934 -1.6641 51.3551
ST486 GDSC1; GDSC2; CTRP2 -1.6438 0.3465 -1.6442 51.2195
KY821 GDSC1; GDSC2 -1.6425 0.1883 -1.6467 48.1033
YT GDSC1; GDSC2 -1.6337 1.4398 -1.7124 48.108
KO52 CTRP2 -1.6293 -0.9161 -1.6293 51.1234
SUP-B15 GDSC1; GDSC2; CTRP2 -1.6261 0.1212 -1.6262 51.1015
PF-382 GDSC1; GDSC2; CTRP2 -1.6049 0.1638 -1.6051 50.9608
KMS-20 CTRP2 -1.5775 1.4093 -1.5874 50.7718
Karpas-422 GDSC1; GDSC2; CTRP2 -1.5744 1.3431 -1.5829 50.7521
HT GDSC1; GDSC2; CTRP2 -1.5519 1.3348 -1.5599 47.4603
SUP-T1 GDSC1; GDSC2; CTRP2 -1.5271 2.2609 -1.5693 50.4314
THP-1 GDSC1; GDSC2 -1.5221 1.0374 -1.558 36.5869
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -1.514 3.0005 -1.6152 47.3238
SUP-HD1 GDSC1; GDSC2; CTRP2 -1.4814 1.0553 -1.4848 50.1376
SU-DHL-4 GDSC1; GDSC2; CTRP2 -1.479 -0.6291 -1.479 46.9934
BL-70 CTRP2 -1.4577 -1.0097 -1.4577 49.9802
DG-75 GDSC1; GDSC2 -1.4555 1.0674 -1.4907 46.3676
MHH-CALL-4 GDSC2; CTRP2 -1.4125 2.4842 -1.4647 46.6536
BCP-1 CTRP2 -1.4119 4.078 -1.6527 49.7057
MM1.S GDSC1; GDSC2; CTRP2 -1.3937 1.2915 -1.3992 49.5556
Loucy GDSC1; GDSC2 -1.3924 -0.1772 -1.3927 45.6741
K-562 GDSC1; GDSC2; CTRP2 -1.385 0.2499 -1.3851 49.4958
TF-1 CTRP2 -1.3744 -0.8708 -1.3744 49.4248
Raji GDSC1; GDSC2; CTRP2 -1.3334 0.4684 -1.3336 49.1519
OCI-AML-3 GDSC1; GDSC2; CTRP2 -1.296 0.8088 -1.2969 48.9037
ME1 CTRP2 -1.2635 2.4185 -1.3058 48.7159
HC-1 GDSC1; GDSC2 -1.2521 1.5728 -1.3234 44.5221
OPM-2 GDSC1; GDSC2; CTRP2 -1.239 0.2517 -1.239 48.5232
MJ CTRP2 -1.224 0.3936 -1.2241 48.4233
Sc-1 GDSC1 -1.2024 1.6371 -1.2781 44.064
SU-DHL-10 GDSC1; GDSC2; CTRP2 -1.1785 1.4664 -1.1844 48.1272
MY-M12 GDSC1; GDSC2 -1.0695 1.4888 -1.4087 20.5277
JJN-3 GDSC1; GDSC2; CTRP2 -1.0238 1.2993 -1.0265 47.0945
Reh GDSC1; GDSC2; CTRP2 -1.0011 0.4848 -1.0011 46.9379
CMK GDSC1; CTRP2 -0.9481 0.0704 -0.9481 46.5851
VL51 GDSC1; GDSC2 -0.9342 1.786 -1.0113 41.5242
KMS-27 CTRP2 -0.8849 0.3205 -0.8849 46.1638
NCI-H929 GDSC1; GDSC2; CTRP2 -0.8438 1.2677 -0.8453 45.8936
KMS-18 CTRP2 -0.7497 2.9059 -0.8049 45.3694
RL GDSC1; GDSC2; CTRP2 -0.7261 1.8036 -0.7325 42.3081
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -0.6651 2.3256 -0.6847 44.7449
L-428 GDSC1; GDSC2; CTRP2 -0.6118 1.4312 -0.6132 44.3486
MHH-CALL-3 CTRP2 -0.599 80.3984 -36.8044 49.4177
HL-60 GDSC1; GDSC2; CTRP2 -0.5889 1.5598 -0.5911 44.1983
EHEB GDSC1; CTRP2 -0.5881 4.6574 -0.8678 44.6766
Karpas-620 GDSC1; GDSC2; CTRP2 -0.4586 3.0005 -0.5084 43.4438
KG-1 GDSC1; GDSC2 -0.3439 1.49 -0.3643 35.612
KMOE-2 GDSC1; GDSC2 -0.2973 1.8142 -0.3408 35.2677
CA46 GDSC1; GDSC2; CTRP2 -0.1334 4.3861 -0.328 41.6352
IM-9 GDSC1; GDSC2 -0.0653 1.8178 -0.0976 32.9711
L-1236 GDSC1; GDSC2; CTRP2 0.0011 8.8504 -1.4843 42.9134
HDLM-2 GDSC1; GDSC2; CTRP2 0.0551 3.569 -0.0188 40.1127
LC4-1 GDSC1; GDSC2 0.0785 4.1372 -0.4697 33.8906
KM-H2 GDSC1; GDSC2; CTRP2 0.1128 2.1065 0.1101 39.5258
DB GDSC1; GDSC2; CTRP2 0.1176 2.8342 0.0973 39.5476
BC-1 GDSC1; GDSC2 0.4646 3.1328 0.2532 28.7255
U266B1 GDSC1; GDSC2; CTRP2 0.5217 3.7582 0.4539 37.0059
MN-60 GDSC1; GDSC2 1.2206 5.9473 0.013 26.5663
RC-K8 GDSC1; GDSC2 1.6086 5.7314 0.503 22.548
ME1 GDSC1; GDSC2 1.8229 6.019 0.5848 21.2942
LP-1 GDSC1; GDSC2; CTRP2 1.9969 4.6267 1.9182 25.5316
SK-MM-2 GDSC1; GDSC2; CTRP2 2.5765 6.8181 2.0234 25.0451
ROS-50 GDSC1; GDSC2 5.7753 12.2573 0.6961 7.9175
MC116 GDSC1; GDSC2; CTRP2 6.7936 7.8685 5.6551 0.5981
REC-1 CTRP2 7.9206 9.6149 5.4768 0.4322
⏷ Show the Full List of 221 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -2.8946 1.3845 -2.9337 59.1219
TE15 CTRP2 -2.4391 4.644 -2.8726 55.3473
KYSE-140 GDSC1; GDSC2; CTRP2 -2.8826 -0.0763 -2.8849 59.4084
OE21 GDSC1; GDSC2; CTRP2 -2.5369 1.8012 -2.5874 56.842
KYSE-270 GDSC1; GDSC2 -2.2502 -0.2179 -2.2547 53.9529
TE-4 GDSC1; GDSC2; CTRP2 -1.692 1.7664 -1.7149 51.5147
KYSE-180 GDSC1; GDSC2; CTRP2 -1.3248 0.159 -1.3248 49.0945
OE33 GDSC1; GDSC2; CTRP2 -1.202 2.5447 -1.25 48.3185
TE-15 GDSC1 -1.02 1.5345 -1.0742 42.2654
TE-11 GDSC1; GDSC2; CTRP2 -0.9763 0.5666 -0.9763 43.8535
TE-10 GDSC1; GDSC2; CTRP2 -0.7318 1.7534 -0.7374 42.3417
T.T GDSC1; GDSC2 -0.6462 1.9943 -0.7316 38.8057
TE-1 GDSC1; GDSC2; CTRP2 -0.5594 2.2015 -0.5724 44.0285
TE-8 GDSC1; GDSC2 -0.239 2.4273 -0.3616 35.0633
KYSE-520 GDSC1; GDSC2; CTRP2 -0.2389 2.5311 -0.2561 41.9095
KYSE-410 GDSC1; GDSC2; CTRP2 -0.2297 3.7163 -0.3357 42.0651
EC-GI-10 GDSC1; GDSC2; CTRP2 -0.1116 2.1705 -0.1171 41.0291
OE19 GDSC1; GDSC2; CTRP2 0.1291 2.8394 0.1089 39.4708
KYSE-450 GDSC1; GDSC2; CTRP2 0.1303 1.485 0.1303 39.4005
TE-9 GDSC1; GDSC2; CTRP2 0.1365 2.0075 0.1348 39.365
TE-5 GDSC1; GDSC2; CTRP2 0.4126 3.1988 0.3831 37.6133
KYSE-30 CTRP2 0.5598 3.0496 0.542 36.5971
TE-14 CTRP2 0.6215 4.2703 0.4993 36.5085
KYSE-70 GDSC1; GDSC2; CTRP2 0.6942 2.9132 0.6842 35.6766
TE-6 GDSC1; GDSC2; CTRP2 1.1022 3.9578 1.0455 33.1126
KYSE-150 GDSC1; GDSC2; CTRP2 1.4706 2.7216 1.4703 30.4722
COLO 680N GDSC1; GDSC2; CTRP2 1.7 4.3817 1.6325 29.1698
KYSE-510 GDSC1; GDSC2; CTRP2 1.7671 5.011 1.6125 27.2096
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 1.2765 3.4365 1.2613 31.815
PaTu 8988s CTRP2 -3.4554 0.0539 -3.4637 62.9841
L3.3 CTRP2 -2.4042 -1.1442 -2.4042 56.2856
Panc 03.27 GDSC1; GDSC2; CTRP2 -2.2154 0.2545 -2.2169 51.4787
TCC-Pan2 CTRP2 -1.3789 5.0432 -1.8071 49.5328
SW1990 GDSC1; GDSC2; CTRP2 -1.3552 2.9624 -1.4441 46.2501
BxPC-3 GDSC1; GDSC2; CTRP2 -1.3061 1.61 -1.3165 45.8343
DAN-G GDSC1; GDSC2; CTRP2 -1.089 0.8966 -1.0897 44.4625
SNU-213 CTRP2 -1.0882 2.3917 -1.1229 47.5617
HuP-T3 GDSC1; GDSC2; CTRP2 -0.9026 4.678 -1.2124 43.859
MIA PaCa-2 GDSC1; GDSC2; CTRP2 -0.691 2.297 -0.7101 42.0304
CFPAC-1 GDSC1; GDSC2; CTRP2 -0.5974 3.6624 -0.7195 41.6886
PK-59 CTRP2 -0.5263 3.5249 -0.628 43.9926
Hs 766T GDSC1; GDSC2; CTRP2 -0.526 4.0844 -0.7016 41.3676
PL4 GDSC1; GDSC2 -0.4698 2.5929 -0.6423 29.1186
HuP-T4 GDSC1; GDSC2; CTRP2 -0.233 2.2302 -0.2412 39.1495
HPAC GDSC1; GDSC2; CTRP2 -0.2281 3.4886 -0.3091 39.3176
Panc 02.03 GDSC1; GDSC2 -0.1145 3.3348 -0.4318 27.0247
Panc 08.13 GDSC1; GDSC2; CTRP2 0.1888 4.0196 0.0716 36.836
Capan-2 GDSC1; GDSC2; CTRP2 0.2337 3.2343 0.1954 36.3319
PSN1 GDSC1; GDSC2; CTRP2 0.3344 2.5332 0.3278 35.6091
SU.86.86 GDSC1; GDSC2; CTRP2 0.3516 3.9836 0.2492 35.7859
PK-45H CTRP2 0.4892 3.3927 0.4502 37.1335
HPAF-II GDSC1; GDSC2; CTRP2 0.5256 6.2456 -0.0345 35.9542
PaTu 8988t GDSC1; GDSC2; CTRP2 0.5347 2.4722 0.5313 34.3509
KP-2 GDSC1; GDSC2; CTRP2 0.6013 2.8798 0.5905 33.9587
Capan-1 GDSC1; GDSC2; CTRP2 0.6386 4.4776 0.4869 34.151
Panc 05.04 CTRP2 0.6428 6.1086 0.1318 37.431
YAPC GDSC1; GDSC2; CTRP2 0.6596 2.948 0.6478 33.5983
Panc 04.03 GDSC1; GDSC2; CTRP2 0.6784 4.2979 0.5562 33.8167
AsPC-1 GDSC1; GDSC2; CTRP2 0.779 5.5951 0.4143 33.9019
MZ-PC-1 GDSC1; GDSC2 0.7986 3.0184 0.6447 19.5408
KP-4 GDSC1; GDSC2; CTRP2 0.8208 2.8239 0.8149 32.5753
Panc 10.05 GDSC1; GDSC2; CTRP2 0.8663 3.9685 0.796 32.4915
KP-3 GDSC1; GDSC2; CTRP2 1.1833 6.0945 0.7255 31.7042
PaTu 8902 GDSC1; GDSC2; CTRP2 1.6014 5.2752 1.3819 28.388
SUIT-2 GDSC1; GDSC2; CTRP2 1.7482 6.1776 1.3188 28.1494
KP-1N GDSC1; GDSC2 1.7631 4.4951 1.2016 14.0438
QGP-1 GDSC1; GDSC2; CTRP2 1.9297 5.3352 1.7258 26.3548
SNU-410 CTRP2 6.7016 20.8835 -0.8348 24.0348
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 0.4998 6.356 -0.0945 38.5265
Hs 944.T CTRP2 -2.9266 4.4734 -3.366 57.8233
G-mel GDSC1; GDSC2 -2.6861 0.0822 -2.7073 45.2683
COLO 679 GDSC1; GDSC2 -2.6247 -0.3563 -2.6311 57.4994
RPMI-7951 GDSC1; GDSC2; CTRP2 -2.4371 0.6318 -2.4436 56.4402
M14 GDSC1; GDSC2 -2.2651 0.4394 -2.2911 54.0024
Mel JuSo GDSC1; GDSC2; CTRP2 -1.9561 2.2012 -2.0105 53.1767
IGR-37 GDSC1; GDSC2; CTRP2 -1.9335 0.2693 -1.9342 53.1461
IST-MEL1 GDSC1; GDSC2 -1.8554 1.878 -2.0096 50.1439
WM793 GDSC1; GDSC2; CTRP2 -1.8451 1.6182 -1.8661 52.5173
WM278 GDSC1; GDSC2 -1.6645 1.9841 -1.8216 48.4535
SK-MEL-30 GDSC1; GDSC2; CTRP2 -1.5169 2.4321 -1.5696 47.2946
Hs 852.T CTRP2 -1.5153 2.6949 -1.588 50.3494
IPC-298 GDSC1; GDSC2; CTRP2 -1.4977 1.5035 -1.5086 47.1271
LOX-IMVI GDSC1; GDSC2; CTRP2 -1.371 1.3617 -1.3774 49.4055
SK-MEL-2 GDSC1; GDSC2; CTRP2 -1.3066 2.454 -1.3527 48.9987
HMCB CTRP2 -1.1657 0.008 -1.1657 48.035
COLO 800 GDSC1; GDSC2; CTRP2 -0.9835 2.0297 -0.9997 43.9368
COLO 783 GDSC1; GDSC2 -0.9327 2.4179 -1.1094 32.6744
451Lu GDSC1; GDSC2 -0.8771 2.3367 -1.0341 32.1872
CHL-1 GDSC1; GDSC2 -0.8591 1.6875 -0.9203 40.7508
WM35 GDSC1; GDSC2 -0.7791 2.6417 -0.9879 40.5018
IGR-39 CTRP2 -0.731 2.4077 -0.7556 45.1912
A2058 GDSC1; GDSC2; CTRP2 -0.6841 1.3906 -0.6857 44.8305
WT2-iPS GDSC1; GDSC2; CTRP2 -0.5537 4.027 -0.7227 41.6106
MDA-MB-435S CTRP2 -0.4394 2.3197 -0.4537 43.2344
Hs 294T CTRP2 -0.3131 2.8337 -0.3466 42.4441
Hs 895.T CTRP2 -0.206 5.4388 -0.6215 42.5247
GAK GDSC1; GDSC2 -0.1125 2.3969 -0.2202 33.7802
WM983B CTRP2 -0.1052 6.8564 -0.905 42.5512
WM88 CTRP2 -0.1018 4.7125 -0.3521 41.551
A-375 GDSC1; GDSC2; CTRP2 -0.0754 2.9435 -0.107 38.319
Hs 940.T GDSC1; GDSC2; CTRP2 -0.0699 3.4995 -0.1436 38.4016
DJM-1 GDSC1; GDSC2 -0.0184 3.242 -0.302 26.2443
G-361 GDSC1; GDSC2; CTRP2 -0.0172 6.653 -0.7465 41.9242
Hs 936.T CTRP2 0.0617 6.9425 -0.7503 41.6007
WM1799 CTRP2 0.0798 5.3928 -0.2993 40.6711
WM1552C GDSC1; GDSC2 0.0872 3.1475 -0.1622 32.5174
A101D GDSC1; GDSC2; CTRP2 0.1129 4.6703 -0.1121 40.1139
MeWo GDSC1; GDSC2; CTRP2 0.2482 4.9779 -0.0251 39.3574
A-431 GDSC1; GDSC2 0.2585 3.3778 -0.0367 24.2166
Hs 938.T GDSC1; GDSC2 0.2714 3.8928 -0.179 24.7443
CJM [Human melanoma] CTRP2 0.4033 1.7797 0.4031 37.5824
COLO 829 GDSC1; GDSC2; CTRP2 0.4484 5.6912 0.03 38.4314
HT-144 GDSC1; GDSC2; CTRP2 0.4987 4.4348 0.3435 37.414
Hs 839.T CTRP2 0.5812 8.4384 -0.708 39.4804
SH-4 GDSC1; GDSC2 0.5838 2.8288 0.4525 27.1776
Hs 934.T CTRP2 0.7121 6.4867 0.0986 37.2521
MZ-MEL-7 GDSC1; GDSC2 0.7867 3.5523 0.489 20.2654
A-388 GDSC1; GDSC2 1.0084 3.4649 0.7566 18.4123
LB2518-MEL GDSC1; GDSC2 1.0191 4.3862 0.455 19.6397
IGR-1 GDSC1; GDSC2; CTRP2 1.0377 4.2412 0.9466 33.6533
WM266-4 CTRP2 1.1229 3.8386 1.0777 32.9374
RVH-421 GDSC1; GDSC2; CTRP2 1.1299 4.754 0.9703 31.1958
HMV-II GDSC1; GDSC2 1.2433 5.0438 0.4289 24.4009
Mel Ho GDSC1; GDSC2; CTRP2 1.3149 5.2913 1.0674 30.319
CP50-MEL-B GDSC1; GDSC2 1.3305 2.6227 1.292 15.1348
SK-MEL-24 GDSC1; GDSC2; CTRP2 1.3415 5.0239 1.1502 31.963
WM115 GDSC1; GDSC2; CTRP2 1.496 4.6152 1.3851 30.6728
SK-MEL-5 GDSC1; GDSC2; CTRP2 1.5236 5.2386 1.305 28.9312
Hs 688(A).T CTRP2 1.7208 6.2843 1.2583 30.35
MZ-MEL-2 GDSC1; GDSC2 2.0476 4.4055 1.5365 11.7407
SK-MEL-3 GDSC1; GDSC2; CTRP2 2.0599 5.5999 1.8088 25.6972
UACC-62 GDSC1; GDSC2; CTRP2 2.2636 5.481 2.0573 25.895
K029AX CTRP2 2.3206 5.5972 2.0934 25.5889
SK-MEL-1 GDSC1; GDSC2; CTRP2 2.3426 5.1988 2.2 25.1485
COLO 741 CTRP2 2.4889 13.9753 -1.1688 34.2696
CP66-MEL GDSC1; GDSC2 2.7426 7.1364 0.9127 12.7433
VMRC-MELG GDSC1; GDSC2 2.8333 4.0505 2.4992 5.1218
COLO 792 GDSC1; GDSC2; CTRP2 2.8664 6.4427 2.4597 22.6039
MMAc-SF GDSC1; GDSC2 2.9039 4.5944 2.3108 5.7979
UACC-257 GDSC1; GDSC2; CTRP2 3.4161 7.6135 2.6348 20.3574
SK-MEL-31 GDSC1; GDSC2; CTRP2 3.5072 13.2463 0.1592 26.9392
LB373-MEL-D GDSC1; GDSC2 3.5641 4.8259 2.761 2.1798
Malme-3M CTRP2 5.1625 22.4498 -2.9043 31.3017
SK-MEL-28 GDSC1; GDSC2; CTRP2 5.8149 13.1093 2.3189 14.9246
EquiPSC Line K2 GDSC1; GDSC2 -0.2026 3.2098 -0.4945 27.6546
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1; GDSC2 -2.9824 0.2214 -3.0205 60.3921
KYSE-220 GDSC1; GDSC2 -2.3199 0.3729 -2.3442 54.5193
OACP4 C GDSC1; GDSC2 -2.3148 2.1391 -2.5517 53.9344
SK-GT-4 GDSC1; GDSC2 -1.7031 1.6578 -1.8136 48.7706
FLO-1 GDSC1; GDSC2 -1.5062 3.1824 -1.9097 47.3046
ESO-26 GDSC1; GDSC2 -0.8869 1.8669 -0.9712 41.0984
TE-12 GDSC1; GDSC2 -0.732 2.956 -1.0079 31.5399
HCE-4 GDSC1; GDSC2 0.1705 1.9207 0.1406 23.8319
KYAE-1 GDSC1; GDSC2 0.2565 3.4108 -0.0482 31.164
KYSE-50 GDSC1; GDSC2 0.6153 2.5472 0.5378 26.6043
OACM5.1 C GDSC1; GDSC2 2.1405 6.3493 0.7382 19.2988
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -1.4801 0.6487 -1.4809 50.1291
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Kelly GDSC1; GDSC2; CTRP2 -4.4703 -3.2937 -4.4703 70.0498
GOTO GDSC1; GDSC2 -4.2757 -0.8478 -4.2995 71.2922
SJNB-14 GDSC1; GDSC2 -3.1452 -1.3751 -3.1457 62.5915
CHP-126 GDSC1; GDSC2; CTRP2 -2.9832 -0.6913 -2.9835 56.3821
SK-N-MC-IXC GDSC1; GDSC2 -2.9448 -1.3539 -2.945 47.1651
SiMa GDSC1; GDSC2; CTRP2 -2.7022 -0.2206 -2.7031 58.2448
SK-N-AS GDSC1; GDSC2; CTRP2 -2.1565 1.0238 -2.1665 54.5823
CHP-212 GDSC1; GDSC2; CTRP2 -2.051 0.7058 -2.055 53.9122
IMR-32 CTRP2 -1.8107 -0.9743 -1.8107 52.3315
NB1 GDSC1; GDSC2; CTRP2 -1.691 1.5303 -1.7059 51.5161
MHH-NB-11 GDSC1; GDSC2; CTRP2 -1.6719 0.1172 -1.672 48.1985
SJNB-13 GDSC1; GDSC2 -1.4157 0.7527 -1.4318 45.9435
CHP-134 GDSC2 -1.411 0.6516 -1.4231 47.5208
NH-6 CTRP2 -1.3973 4.4845 -1.7104 49.6259
SJNB-17 GDSC1; GDSC2 -1.2656 -0.1704 -1.2657 34.5272
NH-12 GDSC1; GDSC2 -1.2453 1.0437 -1.271 44.3327
KP-N-SI9s CTRP2 -1.1643 1.8016 -1.1772 48.0408
SK-N-DZ GDSC1; GDSC2; CTRP2 -1.1247 0.4976 -1.1248 47.7618
KP-N-YS GDSC1; GDSC2 -1.0158 0.9579 -1.1886 19.2092
NB69 GDSC1; GDSC2 -0.9212 1.7188 -0.9896 41.3704
GI-ME-N GDSC1; GDSC2 -0.8699 4.3984 -1.5861 42.6033
TGW GDSC1; GDSC2 -0.7686 0.9257 -0.7762 39.6639
KP-N-YN GDSC1; GDSC2; CTRP2 -0.7424 3.4166 -0.8445 45.3965
LA-N-6 GDSC1; GDSC2 -0.5098 2.3782 -0.6451 29.3532
SJNB-10 GDSC1; GDSC2 -0.5095 1.2334 -0.522 37.1781
SK-N-BE(2)-M17 GDSC1; GDSC2 -0.473 0.4702 -0.4731 36.7665
SJNB-7 GDSC1; GDSC2 -0.4303 1.8745 -0.4874 36.6128
SK-N-FI GDSC1; GDSC2; CTRP2 -0.3747 3.062 -0.4255 42.8928
KP-N-RT-BM-1 GDSC2 -0.3634 3.1335 -1.3418 17.5358
SJNB-6 GDSC1; GDSC2 -0.0688 1.9665 -0.1152 25.6958
SK-N-SH GDSC1; GDSC2; CTRP2 0.0865 3.95 -0.0284 40.0135
NB(TU)1 GDSC1; GDSC2 0.0897 3.4064 -0.2289 32.8058
SJNB-5 GDSC1; GDSC2 0.1133 1.9971 0.0736 24.2995
IMR-5 GDSC1; GDSC2 0.4332 2.3227 0.3754 28.2696
SK-N-BE(2) CTRP2 0.4761 6.4987 -0.1624 38.7735
SJNB-12 GDSC1; GDSC2 2.4546 5.5281 1.433 14.2198
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -1.3542 2.6302 -1.4145 49.3125
SNU-1079 CTRP2 -1.1791 1.3885 -1.1839 48.1298
SNU-1196 CTRP2 -0.775 2.7402 -0.8194 45.5172
HuCC-T1 GDSC1; GDSC2; CTRP2 -0.2212 2.3783 -0.233 41.7768
HuH-28 CTRP2 0.4441 3.5159 0.3941 37.4667
SNU-308 CTRP2 0.5626 5.1829 0.2732 37.3675
SNU-869 CTRP2 1.0355 6.8965 0.3237 35.4856
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-BR-3 CTRP2 -4.4284 2.2097 -4.6114 66.3431
HCC1806 GDSC1; GDSC2; CTRP2 -3.2574 -1.3522 -3.2575 57.9734
HCC1143 GDSC1; GDSC2; CTRP2 -2.7157 1.6498 -2.7635 54.4364
HCC1395 GDSC1; GDSC2; CTRP2 -2.3486 2.0751 -2.41 52.2263
HCC1569 GDSC1; GDSC2 -2.2495 1.1259 -2.3292 42.0504
HCC1599 GDSC1; GDSC2 -1.932 1.7766 -2.0758 39.8835
Hs 578T GDSC1; GDSC2; CTRP2 -1.8727 2.3235 -1.9322 52.638
HCC70 GDSC1; GDSC2 -1.6582 0.97 -1.6948 37.5129
CAL-51 GDSC1; GDSC2; CTRP2 -1.2172 0.9689 -1.2186 45.2629
BT-549 GDSC1; GDSC2; CTRP2 -1.0327 2.7565 -1.0887 44.2261
HCC38 GDSC1; GDSC2; CTRP2 -0.9441 3.4132 -1.0577 43.7884
HCC1187 GDSC1; GDSC2 -0.9156 3.3961 -1.3231 33.2741
HCC1954 GDSC1; GDSC2; CTRP2 -0.4949 2.5992 -0.5217 40.8312
DU4475 GDSC1; GDSC2; CTRP2 -0.4903 1.5648 -0.492 40.7339
JIMT-1 GDSC1; GDSC2; CTRP2 -0.4011 2.7343 -0.4319 40.2588
MDA-MB-468 GDSC1; GDSC2; CTRP2 -0.2938 2.4639 -0.3097 39.5504
CAL-148 GDSC2; CTRP2 -0.1388 2.9429 -0.1726 38.6363
MDA-MB-453 GDSC1; GDSC2; CTRP2 -0.0694 2.9842 -0.1031 38.2045
MFM-223 GDSC1; GDSC2 0.0767 2.6808 -0.0675 24.9161
CAL-85-1 GDSC1; GDSC2; CTRP2 0.1114 2.4857 0.1025 37.0057
HDQ-P1 GDSC1; GDSC2; CTRP2 0.1315 2.7863 0.1136 36.9076
MDA-MB-157 GDSC1; GDSC2; CTRP2 0.2003 5.1583 -0.1152 37.2899
AU565 GDSC1; GDSC2; CTRP2 0.2699 4.4037 0.1028 36.4731
MDA-MB-231 GDSC1; GDSC2; CTRP2 0.4155 2.9952 0.3963 35.1423
HCC1937 GDSC1; GDSC2; CTRP2 0.4933 5.9807 0.0035 35.9681
COLO 824 GDSC1; GDSC2 0.6676 3.5484 0.3603 21.1422
CAL-120 GDSC1; GDSC2; CTRP2 0.7368 3.8859 0.6679 33.293
BT-20 GDSC1; GDSC2; CTRP2 0.8811 3.2387 0.8638 32.2352
HMC-1-8 CTRP2 0.8982 2.8571 0.8927 34.3029
Evsa-T GDSC1; GDSC2 1.1504 4.7279 0.4612 19.1456
MRK-nu-1 GDSC1; GDSC2 1.2118 3.2655 1.0342 16.5377
HCC202 GDSC1; GDSC2; CTRP2 1.2325 5.2361 0.9895 30.7498
MDA-MB-361 GDSC1; GDSC2; CTRP2 1.2336 8.0846 0.1238 33.2267
YMB-1-E GDSC2 1.2567 5.5277 -1.0536 11.1008
HCC2157 GDSC1; GDSC2 1.4596 5.0692 0.6432 17.4089
MDA-MB-175-VII GDSC1; GDSC2 1.7759 5.369 0.8357 15.6249
EFM-19 GDSC1; GDSC2 1.8068 6.1234 0.5202 16.9429
MDA-MB-415 GDSC1; GDSC2 1.9497 4.8393 1.2484 13.2785
OCUB-M GDSC1; GDSC2 2.0155 5.9882 0.7887 15.1598
MDA-MB-436 GDSC1; GDSC2 2.2598 6.8196 0.6246 15.2468
MDA-MB-330 GDSC1; GDSC2 2.5667 6.0348 1.2942 11.3787
MCF-7 GDSC1; GDSC2; CTRP2 3.0849 8.6362 1.8662 22.6088
UACC-812 GDSC2; CTRP2 3.988 7.5189 3.2772 15.2735
BT-474 GDSC1; GDSC2; CTRP2 4.1825 5.9442 4.0389 12.072
BT-483 GDSC1; GDSC2 4.2279 10.7156 0.3503 12.0441
HCC1428 GDSC1; GDSC2; CTRP2 4.3033 10.3207 2.3253 18.0136
T-47D GDSC1; GDSC2; CTRP2 4.3168 6.9096 3.8682 12.2977
EFM-192A GDSC1; GDSC2 4.7352 9.9563 1.096 7.8007
HCC1419 GDSC1; GDSC2; CTRP2 5.1082 9.9952 3.2432 12.8158
ZR-75-1 CTRP2 5.2067 9.1656 3.7405 11.4276
Hs 578Bst CTRP2 5.23 6.1638 5.1204 5.8141
HCC2218 GDSC1; GDSC2; CTRP2 5.3274 13.6389 1.6343 18.2756
UACC-893 GDSC1; GDSC2 5.3722 8.545 2.1563 2.3467
ZR-75-30 GDSC1; GDSC2; CTRP2 5.4666 6.8407 5.1011 4.9045
CAMA-1 GDSC1; GDSC2; CTRP2 5.6144 13.1758 2.1143 16.0209
HCC1500 GDSC1; GDSC2; CTRP2 5.7568 11.4879 3.0794 12.151
BT 428 CTRP2 -0.4227 4.1567 -0.602 43.4664
BT 440 CTRP2 -0.37 4.9704 -0.6946 43.3863
BT 179 CTRP2 -0.1186 3.0114 -0.1558 41.1643
BT 159 CTRP2 0.0477 3.4996 -0.0199 40.1445
BT 416 CTRP2 0.2958 2.3869 0.2912 38.3129
BT 245 CTRP2 0.4373 5.0844 0.1581 38.1519
BT 271 CTRP2 0.7285 4.6442 0.5566 35.9503
BT 172 CTRP2 0.8514 3.9548 0.7816 34.8228
BT 131 CTRP2 1.0591 3.9888 0.9971 33.4168
BT 482 CTRP2 1.0753 4.9635 0.8737 33.7553
BT147 CTRP2 1.2827 4.8042 1.1263 32.2387
BT 145 CTRP2 1.2847 3.9128 1.2408 31.8556
BT 498 CTRP2 1.5562 11.229 -0.8352 36.3645
BT 112 CTRP2 1.602 3.6799 1.5849 29.6529
BT164 CTRP2 1.7998 4.7454 1.6913 28.644
BT 504 CTRP2 1.8363 2.866 1.8362 28.035
BT 286 CTRP2 1.8926 3.3914 1.8895 27.6705
BT 139 CTRP2 1.9628 3.082 1.9625 27.1932
BT 228 CTRP2 2.018 5.1866 1.8512 27.3912
BT 330 CTRP2 2.0361 3.866 2.0226 26.749
BT 224 CTRP2 2.1003 3.9165 2.0864 26.3224
BT 232 CTRP2 2.222 3.5067 2.2203 25.4712
BT 333 CTRP2 2.2334 6.3222 1.8063 26.8636
BT 444 CTRP2 2.2546 3.0748 2.2546 25.2483
BT 359 CTRP2 2.3577 5.395 2.1779 25.177
BT 239 CTRP2 2.3834 6.1689 2.0144 25.6691
BT 328 CTRP2 2.4541 3.1037 2.4541 23.9194
BT 231 CTRP2 2.4697 7.9156 1.5101 27.1564
BT 422 CTRP2 2.603 4.8286 2.5374 23.1489
BT 340 CTRP2 2.6067 4.3665 2.5851 22.9746
BT 216 CTRP2 2.6355 5.9266 2.3557 23.6816
BT 187 CTRP2 3.0185 6.2471 2.6846 21.3313
BT 320 CTRP2 4.0049 6.5579 3.6599 14.8213
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -1.1821 0.4655 -1.1822 48.1444
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 -4.3566 2.0301 -4.5145 66.2181
SF539 GDSC1; GDSC2; CTRP2 -3.3883 -0.5718 -3.3899 62.738
D283 Med GDSC1; GDSC2; CTRP2 -3.0589 -1.0806 -3.059 60.6393
LNZTA3WT4 GDSC1 -2.6636 0.4987 -2.7078 57.5353
D-566MG GDSC1; GDSC2 -2.3256 -0.3826 -2.3286 42.5145
GI-1 GDSC1; GDSC2 -2.1882 0.0143 -2.1963 53.3426
T98G GDSC1; GDSC2; CTRP2 -2.1429 0.8822 -2.1501 54.5047
H4 GDSC1; GDSC2 -1.8724 0.8942 -1.9124 50.3127
MOG-G-UVW GDSC1; GDSC2 -1.7956 0.5535 -1.8133 49.5856
42-MG-BA GDSC1; GDSC2; CTRP2 -1.7925 1.574 -1.8107 52.1772
PFSK-1 GDSC1; GDSC2 -1.6218 1.4048 -1.6959 47.993
SK-MG-1 GDSC1; GDSC2 -1.6116 0.4117 -1.6203 47.8133
ONS-76 GDSC1; GDSC2; CTRP2 -1.5218 1.4474 -1.5318 50.4039
8-MG-BA GDSC1; GDSC2; CTRP2 -1.5203 1.2588 -1.5266 50.3947
SNU-738 CTRP2 -1.4072 0.5396 -1.4076 49.6441
KALS-1 GDSC1; GDSC2; CTRP2 -1.3968 2.8593 -1.4782 49.5918
D-423MG GDSC1; GDSC2 -1.3845 2.3243 -1.5804 36.1016
LN-18 GDSC1; GDSC2; CTRP2 -1.311 0.7477 -1.3118 49.0035
D-336MG GDSC1; GDSC2 -1.2728 1.9973 -1.4028 35.0481
LN-229 GDSC1; GDSC2; CTRP2 -1.1292 1.2763 -1.1323 47.7959
SW1088 GDSC1; GDSC2; CTRP2 -1.0457 2.99 -1.1215 47.3272
SF295 GDSC1; GDSC2; CTRP2 -0.9446 2.8173 -1.0014 43.7796
MOG-G-CCM GDSC1; GDSC2 -0.8865 1.5977 -0.9399 40.9849
SF268 GDSC1; GDSC2; CTRP2 -0.6224 2.986 -0.6781 44.5346
D-392MG GDSC1; GDSC2 -0.6029 3.8036 -1.1019 39.8073
GaMG GDSC1; GDSC2; CTRP2 -0.6019 2.5025 -0.6273 44.3385
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -0.5567 3.4051 -0.9339 39.0158
YH-13 GDSC1; GDSC2; CTRP2 -0.5565 3.7326 -0.6849 44.2371
Hs 683 GDSC1; GDSC2; CTRP2 -0.5179 1.6729 -0.5207 40.9984
Becker GDSC1; GDSC2; CTRP2 -0.4792 3.194 -0.5454 43.6143
Daoy GDSC1; GDSC2; CTRP2 -0.4422 2.2753 -0.4552 43.2495
SF126 GDSC1; GDSC2; CTRP2 -0.4253 2.1016 -0.4336 40.436
KNS-81 CTRP2 -0.4077 7.4117 -1.4128 44.519
D-263MG GDSC1; GDSC2 -0.0907 2.0611 -0.149 33.3406
A-172 GDSC1; GDSC2; CTRP2 0.0678 2.7131 0.0511 39.8686
M059J GDSC1; GDSC2 0.0749 2.2763 -0.0006 31.8218
DBTRG-05MG GDSC1; GDSC2; CTRP2 0.1917 3.433 0.1369 39.1562
TM-31 CTRP2 0.2635 3.2216 0.2272 38.6256
GMS-10 CTRP2 0.2731 2.5093 0.2661 38.4718
CAS-1 GDSC1; GDSC2; CTRP2 0.282 3.8609 0.1899 44.391
KG-1-C CTRP2 0.3738 4.3143 0.228 38.2086
SNU-1105 CTRP2 0.3901 3.1392 0.3631 37.7554
AM-38 GDSC1; GDSC2; CTRP2 0.5147 3.4658 0.4717 36.9763
SNB-75 GDSC1; GDSC2; CTRP2 0.5254 3.3909 0.488 34.5883
CCF-STTG1 CTRP2 0.5949 4.2325 0.4761 36.6739
SNU-626 CTRP2 0.6053 3.5455 0.5601 36.381
LN-405 GDSC1; GDSC2 0.6745 3.9013 0.256 27.7433
KINGS-1 GDSC1; GDSC2 0.8721 4.5176 0.2478 26.9019
SNU-489 CTRP2 0.9296 4.1432 0.8436 34.3546
U-118MG GDSC1; GDSC2; CTRP2 0.933 4.7825 0.7531 34.6267
YKG-1 GDSC1; GDSC2; CTRP2 0.9488 3.4509 0.9231 31.9088
GOS-3 CTRP2 1.051 3.607 1.0196 33.3706
GB-1 GDSC1; GDSC2; CTRP2 1.1596 4.685 1.0137 33.0209
D-542MG GDSC1; GDSC2 1.2192 5.6707 0.1342 20.388
D-502MG GDSC1; GDSC2 1.3009 4.4606 0.7269 17.5804
NMC-G1 GDSC1; GDSC2; CTRP2 1.3328 4.392 1.2414 29.7176
Onda 11 GDSC1; GDSC2 1.3387 4.103 0.9033 16.7044
M059K CTRP2 1.3505 1.9172 1.3505 31.2714
D-245MG GDSC2 1.41 7.5456 -1.9377 15.4211
D-247MG GDSC1; GDSC2 1.7548 4.3708 1.2436 13.9228
U-87MG ATCC GDSC1; GDSC2; CTRP2 1.891 6.1366 1.4862 29.0429
SNU-201 CTRP2 1.9437 3.4926 1.9395 27.3334
U-251MG GDSC1; GDSC2; CTRP2 2.1362 3.972 2.1208 26.0885
DK-MG GDSC1; GDSC2; CTRP2 2.1835 9.9438 0.3716 31.5422
KNS-81-FD GDSC1; GDSC2 2.2164 5.6615 1.1389 13.0535
Onda 10 GDSC1; GDSC2 2.2578 4.0961 1.8854 9.5646
KNS-42 GDSC1; GDSC2; CTRP2 2.4239 5.8028 2.1565 23.4833
SNU-466 CTRP2 2.4649 3.0943 2.4649 23.8469
SW1783 GDSC1; GDSC2; CTRP2 7.0581 15.8146 1.9762 14.7688
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -1.2839 2.2781 -1.4629 45.0573
ETK-1 GDSC1; GDSC2 -0.8999 2.7177 -1.1357 41.6971
TGBC1TKB GDSC1; GDSC2 0.5719 4.2256 0.0331 29.2944
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-3 CTRP2 -3.1342 1.6169 -3.1953 60.4144
ESS-1 GDSC1; GDSC2; CTRP2 -2.622 -1.3946 -2.622 57.737
JHUEM-7 CTRP2 -2.5144 2.0572 -2.5813 56.6342
JHUEM-1 CTRP2 -1.7985 0.594 -1.8001 52.2459
HEC-6 CTRP2 -1.7601 0.0724 -1.7602 51.994
MFE-296 GDSC1; GDSC2; CTRP2 -1.6007 3.1653 -1.7249 50.8758
HEC-1-B CTRP2 -1.4715 2.677 -1.5407 50.0692
EN GDSC1; GDSC2; CTRP2 -1.0596 3.7637 -1.2258 47.4985
JHUEM-2 CTRP2 -0.9946 0.3148 -0.9946 46.895
MFE-319 GDSC1; GDSC2; CTRP2 -0.7635 0.5445 -0.7635 45.3552
HEC-1-A CTRP2 -0.2221 6.3729 -0.8869 43.0279
AN3-CA GDSC1; GDSC2; CTRP2 -0.199 2.1187 -0.2047 41.6117
RL95-2 GDSC1; GDSC2; CTRP2 0.2331 2.1625 0.2307 38.7234
HEC-50B CTRP2 0.5472 5.8305 0.1022 37.8702
HEC-151 CTRP2 0.6097 5.2192 0.3166 37.0722
HEC-59 CTRP2 0.7294 4.4569 0.5877 35.854
HEC-251 CTRP2 1.1639 6.1952 0.6763 34.0433
HEC-108 CTRP2 1.2009 7.9841 0.1258 35.4095
KLE GDSC1; GDSC2; CTRP2 1.5141 11.6442 -1.0624 36.9371
MFE-280 GDSC1; GDSC2 1.676 4.694 1.0275 19.4305
HEC-265 CTRP2 2.3645 6.2209 1.9788 25.8529
EFE-184 CTRP2 3.0404 6.7916 2.5354 21.8092
Ishikawa (Heraklio) 02 ER- CTRP2 -0.436 1.6511 -0.438 43.1792
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB1047-RCC GDSC1; GDSC2 -2.8394 1.3752 -2.988 46.594
ACHN GDSC1; GDSC2; CTRP2 -2.7431 0.502 -2.7508 58.4249
769-P GDSC1; GDSC2; CTRP2 -2.0266 0.8079 -2.0315 53.7471
KTCTL-140 GDSC1; GDSC2 -1.8988 0.7298 -1.9289 39.3956
LB2241-RCC GDSC1; GDSC2 -1.8331 1.3284 -1.9109 39.0564
TUHR4TKB CTRP2 -1.4099 2.9816 -1.5036 49.6768
RXF 393L GDSC1; GDSC2 -1.3242 1.2571 -1.3684 35.1297
786-O GDSC1; GDSC2; CTRP2 -1.2278 1.1612 -1.2305 48.4517
KTCTL-13 GDSC1; GDSC2 -1.1598 2.0662 -1.2924 34.2133
NCC010 GDSC1; GDSC2 -1.067 1.7828 -1.1521 33.3469
TK-10 GDSC1; GDSC2 -1.0157 2.3988 -1.1956 42.6034
BFTC-909 GDSC1; GDSC2; CTRP2 -0.9382 1.3645 -0.9408 46.5244
BB65-RCC GDSC1; GDSC2 -0.8739 2.821 -1.1307 32.5249
CAL-54 GDSC1; GDSC2; CTRP2 -0.8731 2.0876 -0.8889 46.1158
A-704 GDSC1; GDSC2 -0.6637 3.6128 -1.1105 40.1884
KMRC-20 GDSC1; GDSC2; CTRP2 -0.6303 3.0886 -0.6946 44.6025
LB996-RCC GDSC1; GDSC2 -0.6005 1.619 -0.6413 39.5432
KTCTL-1M GDSC1; GDSC2 -0.3358 3.6306 -0.7582 29.1458
UO-31 GDSC1; GDSC2; CTRP2 -0.3168 2.0749 -0.3231 39.7528
Caki-1 GDSC1; GDSC2; CTRP2 -0.2444 2.6785 -0.2678 39.3496
HA7-RCC GDSC1; GDSC2 -0.2392 3.2683 -0.5499 28.0006
OS-RC-2 GDSC1; GDSC2; CTRP2 -0.1434 3.7503 -0.2482 41.4971
KTCTL-21 GDSC1; GDSC2 -0.084 4.8816 -0.913 28.8242
KTCTL-26A GDSC1; GDSC2 -0.049 2.8816 -0.2467 26.136
KTCTL-195 GDSC1; GDSC2 -0.0454 2.2882 -0.131 33.0314
KMRC-1 GDSC1; GDSC2; CTRP2 0.1565 2.5489 0.1468 39.2569
KMRC-3 CTRP2 0.1927 5.5445 -0.2125 40.0174
KMRC-2 CTRP2 0.3091 2.4618 0.3035 38.2278
SN12C GDSC1; GDSC2 0.3389 4.4727 -0.307 31.931
NCC021 GDSC1; GDSC2 0.4018 3.9725 -0.0637 23.8334
A-498 GDSC1; GDSC2 0.4112 4.2297 -0.1418 30.855
VMRC-RCZ GDSC1; GDSC2; CTRP2 0.6403 4.1988 0.5291 36.3509
SW13 GDSC1; GDSC2 0.6888 2.4862 0.6258 25.8204
VMRC-RCW GDSC1; GDSC2; CTRP2 0.8064 4.5252 0.6597 33.1682
SW156 GDSC1; GDSC2 0.9713 3.8564 0.5931 19.2142
TUHR14TKB CTRP2 1.0393 7.5857 0.0953 36.0584
Caki-2 CTRP2 2.0397 5.721 1.7578 27.6425
SNU-1272 CTRP2 2.7167 8.7563 1.4316 26.6869
RCC10RGB GDSC1; GDSC2; CTRP2 2.969 6.3471 2.6008 21.7843
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 59 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1; GDSC2; CTRP2 -3.102 1.845 -3.1782 56.6056
LoVo GDSC1; GDSC2; CTRP2 -2.3272 0.7432 -2.3341 52.1634
SNU-C5 GDSC1; GDSC2; CTRP2 -2.0552 2.5319 -2.1398 50.4624
MDST8 GDSC1; GDSC2; CTRP2 -1.9798 -0.5969 -1.9798 50.0125
SNU-C2A CTRP2 -1.5544 2.412 -1.6073 50.6053
RKO GDSC1; GDSC2; CTRP2 -1.5356 1.6063 -1.5498 47.2643
SK-CO-1 GDSC1; GDSC2; CTRP2 -1.4591 2.6327 -1.5242 46.8542
GP2d CTRP2 -1.4184 1.2939 -1.4243 49.7198
HT-29 GDSC1; GDSC2; CTRP2 -1.4059 1.5652 -1.4168 46.4551
HCC-56 CTRP2 -1.3694 0.3429 -1.3696 49.3922
SNU-283 GDSC2 -1.2984 2.0119 -1.8425 23.6215
SW48 GDSC1; GDSC2; CTRP2 -1.1547 1.0588 -1.1562 44.8735
GP5d GDSC1; GDSC2 -1.0374 0.5728 -1.0412 32.7374
CCK-81 GDSC1; GDSC2; CTRP2 -1.0241 2.3077 -1.0525 44.1194
HCC2998 GDSC1; GDSC2 -0.9474 1.2648 -0.976 32.1542
COLO 320HSR GDSC1; GDSC2 -0.9241 1.836 -1.0068 32.1812
LS411N GDSC1; GDSC2; CTRP2 -0.8434 2.1995 -0.8624 42.9774
DiFi GDSC1; GDSC2 -0.732 3.4343 -1.1334 31.9096
SNU-C1 GDSC1; GDSC2; CTRP2 -0.6682 2.2605 -0.6854 41.884
NCI-H716 GDSC1; GDSC2; CTRP2 -0.6123 2.2669 -0.6285 41.5332
SNU-C2B GDSC1; GDSC2 -0.57 3.7145 -1.0388 30.9635
T84 GDSC1; GDSC2; CTRP2 -0.3387 4.0139 -0.4907 40.1731
SW626 GDSC1; GDSC2 -0.3083 3.4859 -0.6858 31.0722
LS513 GDSC1; GDSC2; CTRP2 -0.2395 2.1141 -0.2456 39.184
CL-11 GDSC1; GDSC2; CTRP2 -0.2325 4.6849 -0.4882 39.7651
SNU-1033 CTRP2 -0.1343 5.1537 -0.4779 41.9451
SNU-503 CTRP2 -0.1203 5.543 -0.5533 42.0268
LS123 GDSC1; GDSC2; CTRP2 -0.0479 3.7027 -0.1415 38.2362
NCI-H508 GDSC1; GDSC2; CTRP2 -0.0153 3.1357 -0.0566 37.8893
SNU-407 GDSC1; GDSC2; CTRP2 0.0653 2.9847 0.0361 37.3534
COLO205 GDSC1; GDSC2; CTRP2 0.0976 1.6725 0.0973 37.0655
HCT 116 GDSC1; GDSC2; CTRP2 0.229 3.0578 0.2012 36.3297
SNU-175 GDSC2 0.2657 2.6485 0.1433 23.413
HCT 15 GDSC1; GDSC2; CTRP2 0.2931 2.5489 0.2855 35.8695
SNU-81 GDSC1; GDSC2; CTRP2 0.3338 3.077 0.3083 35.6702
OUMS-23 CTRP2 0.4755 5.5036 0.1055 38.1387
SW1463 GDSC1; GDSC2; CTRP2 0.4808 4.5694 0.3024 35.2042
CaR-1 GDSC1; GDSC2 0.5137 2.4465 0.4442 21.3456
SW948 GDSC1; GDSC2; CTRP2 0.5183 2.9003 0.5051 34.4832
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2 0.5194 4.8007 0.3032 35.0734
SW620 GDSC1; GDSC2; CTRP2 0.5345 2.7955 0.5248 34.3719
COLO201 CTRP2 0.5596 2.7719 0.551 36.5687
LS180 GDSC1; GDSC2; CTRP2 0.57 4.2167 0.4517 34.4777
SW1417 GDSC1; GDSC2; CTRP2 0.6196 5.3777 0.292 34.7709
SNU-C4 CTRP2 0.678 5.661 0.288 36.8932
NCI-H747 GDSC1; GDSC2; CTRP2 0.7022 3.0652 0.6873 33.3427
SW837 GDSC1; GDSC2 0.9955 4.0597 0.5492 19.2679
SNU-61 GDSC1; GDSC2; CTRP2 1.0154 4.0791 0.9417 33.7456
HT-55 GDSC1; GDSC2; CTRP2 1.1296 5.1007 0.9058 31.3278
C2BBe1 GDSC1; GDSC2; CTRP2 1.328 5.6247 1.0055 30.4051
LS1034 GDSC1; GDSC2; CTRP2 1.425 4.2541 1.3556 29.0093
HT115 GDSC1; GDSC2; CTRP2 1.5594 2.7651 1.5591 27.9546
DLD-1 CTRP2 1.6338 3.3364 1.6286 29.4013
COLO 320 CTRP2 1.798 6.4994 1.2784 30.0328
COLO 678 GDSC1; GDSC2; CTRP2 2.1223 5.4604 1.9082 25.1328
CW-2 GDSC1; GDSC2; CTRP2 2.4049 5.7214 2.1558 23.4895
SW1116 GDSC1; GDSC2 2.6492 5.5705 1.5974 9.7581
HCT 8 CTRP2 2.7917 5.0974 2.7012 21.9777
SNU-1040 GDSC1; GDSC2 5.9669 17.515 -1.7092 16.8077
⏷ Show the Full List of 59 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 2.9093 7.3533 0.9528 15.5374
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 -2.8435 2.8259 -3.0032 58.2205
SNU-182 CTRP2 -1.8829 1.2236 -1.8932 52.7845
SNU-878 CTRP2 -1.3546 2.9138 -1.4389 49.3223
SNU-398 GDSC1; GDSC2; CTRP2 -1.1202 3.1793 -1.2182 47.8277
SNU-387 GDSC1; GDSC2; CTRP2 -1.0751 3.6187 -1.2224 47.5802
HuH-1 GDSC1; GDSC2; CTRP2 -0.9993 3.4354 -1.1188 47.073
HLF CTRP2 -0.9217 1.7637 -0.9298 53.5808
SNU-886 CTRP2 -0.6706 4.4198 -0.9128 51.4918
Hep-G2 CTRP2 -0.6438 4.2607 -0.8564 44.9296
JHH-1 GDSC1; GDSC2 -0.5138 1.4085 -0.5353 37.2608
JHH-2 GDSC1; GDSC2; CTRP2 -0.4411 3.8805 -0.5814 43.5123
Li-7 CTRP2 -0.2016 4.4655 -0.415 42.1139
SNU-423 GDSC1; GDSC2; CTRP2 -0.0973 2.3802 -0.107 40.9463
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -0.0949 3.2361 -0.1468 38.4974
SNU-761 CTRP2 -0.0372 4.4524 -0.2356 41.0224
JHH-5 CTRP2 0.4891 3.683 0.4268 37.2057
Huh-7 GDSC1; GDSC2 0.5032 5.1578 -0.3958 31.536
HLE GDSC1; GDSC2 0.573 3.6082 0.2391 28.291
JHH-4 GDSC1; GDSC2; CTRP2 1.3633 2.6676 1.3629 31.1876
JHH-6 GDSC1; GDSC2; CTRP2 1.3738 2.8448 1.3726 31.1201
JHH-7 GDSC1; GDSC2 1.9563 5.1606 1.1121 17.8732
SNU-449 GDSC1; GDSC2; CTRP2 2.1158 4.3153 2.077 26.3032
PLC/PRF/5 CTRP2 2.3825 6.1217 2.0267 25.6286
SNU-475 CTRP2 2.4501 4.0091 2.4412 23.9753
SK-HEP-1 GDSC1; GDSC2; CTRP2 2.5379 4.5417 2.4997 23.4894
Hep-G2/C3A GDSC1; GDSC2 2.9673 6.7431 1.3075 13.2958
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1703 GDSC1; GDSC2; CTRP2 -6.2397 2.1278 -6.5309 72.7303
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 -3.2623 -1.1542 -3.2624 61.9861
LC-1/sq GDSC1; GDSC2 -3.0687 -0.3193 -3.0838 61.4738
EPLC-272H GDSC1; GDSC2; CTRP2 -2.6233 1.4277 -2.6565 57.4686
RERF-LC-Sq1 GDSC1; GDSC2 -2.6015 1.9897 -2.8336 56.2148
SK-LU-1 GDSC1; GDSC2; CTRP2 -2.4634 3.4245 -2.6785 55.8998
NCI-H2122 GDSC1; GDSC2; CTRP2 -2.4172 -0.515 -2.4173 56.3695
NCI-H1734 GDSC1; GDSC2; CTRP2 -2.4056 1.2347 -2.4257 52.7368
COLO 699 CTRP2 -2.1504 -0.9105 -2.1504 54.5948
A-427 GDSC1; GDSC2 -2.1127 -0.0275 -2.1188 40.9231
LB647-SCLC GDSC1; GDSC2 -2.0966 0.2762 -2.1108 40.8288
NCI-H2795 GDSC1; GDSC2 -2.0409 0.4744 -2.0619 51.9129
MOR/CPR CTRP2 -2.0058 -1.2341 -2.0058 53.6314
Lu-99 CTRP2 -2.0002 -0.7496 -2.0002 53.594
CPC-N GDSC1; GDSC2 -1.9243 0.2869 -1.9353 50.8168
NCI-H1755 GDSC1; GDSC2; CTRP2 -1.8484 1.3982 -1.8624 52.5503
NCI-H1341 GDSC1; GDSC2; CTRP2 -1.8164 0.6007 -1.8181 52.3646
NCI-H1876 GDSC1; GDSC2 -1.7452 0.4426 -1.7574 49.1006
COR-L47 CTRP2 -1.7244 2.1551 -1.7673 51.7076
LUDLU-1 CTRP2 -1.698 0.8302 -1.7008 51.5765
DV-90 CTRP2 -1.6505 2.0202 -1.6836 51.2365
PC-14 GDSC1; GDSC2; CTRP2 -1.6415 1.0559 -1.6462 48.0144
COR-L23 GDSC1; GDSC2 -1.6011 0.4208 -1.6098 47.7123
NCI-H64 GDSC1; GDSC2 -1.5589 1.4605 -1.6355 47.411
HCC33 GDSC2 -1.5544 0.8455 -1.7471 24.209
NCI-H2110 GDSC1; GDSC2; CTRP2 -1.549 1.0203 -1.5526 47.4366
NCI-H647 GDSC1; GDSC2; CTRP2 -1.536 0.7105 -1.5372 47.3518
LCLC-97TM1 GDSC1; GDSC2; CTRP2 -1.5033 1.6258 -1.5174 50.2807
EMC-BAC-2 GDSC1; GDSC2 -1.4991 1.7503 -1.6085 46.903
Sq-1 CTRP2 -1.4456 1.0326 -1.4485 49.8994
CAL-12T GDSC1; GDSC2; CTRP2 -1.3875 1.5961 -1.3989 46.4424
NCI-H1568 GDSC1; GDSC2; CTRP2 -1.3862 1.0715 -1.3892 49.5052
SK-MES-1 GDSC1; GDSC2; CTRP2 -1.378 2.2291 -1.4133 49.4602
NCI-H2461 GDSC1; GDSC2 -1.3669 4.7009 -2.2285 46.6525
LOU-NH91 GDSC1; GDSC2; CTRP2 -1.2508 3.5723 -1.4036 48.6906
HCC827 GDSC1; GDSC2; CTRP2 -1.2435 2.0365 -1.2659 48.5717
NCI-H1184 CTRP2 -1.1968 2.3167 -1.231 48.2743
NCI-H2023 GDSC1; GDSC2; CTRP2 -1.1519 5.033 -1.5579 48.2105
NCI-H838 GDSC1; GDSC2; CTRP2 -1.1298 2.7329 -1.1883 44.9247
NCI-H1944 GDSC1; GDSC2; CTRP2 -1.0967 1.9083 -1.1114 47.5955
EMC-BAC-1 GDSC1; GDSC2 -1.061 2.0911 -1.1902 33.4624
NCI-H211 GDSC1; GDSC2; CTRP2 -1.0432 1.0415 -1.0443 47.2206
NCI-H1155 GDSC1; GDSC2; CTRP2 -1.0381 1.0002 -1.039 47.1863
NCI-H727 GDSC1; GDSC2; CTRP2 -1.0201 3.2286 -1.1177 47.184
HOP-62 GDSC1; GDSC2; CTRP2 -1.0089 3.513 -1.1384 47.1443
COR-L105 GDSC1; GDSC2; CTRP2 -0.9954 4.3603 -1.2527 47.1741
NCI-H2286 CTRP2 -0.9888 3.1318 -1.075 46.9705
HCC4006 CTRP2 -0.9787 3.1096 -1.0622 46.9019
NCI-H2731 GDSC1; GDSC2 -0.9579 2.4062 -1.1344 42.0595
NCI-H661 GDSC1; GDSC2; CTRP2 -0.9371 4.2548 -1.1713 46.7935
NCI-H524 GDSC1; GDSC2; CTRP2 -0.8876 1.2776 -0.8893 46.1857
VMRC-LCD GDSC1; GDSC2; CTRP2 -0.8846 3.3775 -0.9907 46.3212
NCI-H1650 GDSC1; GDSC2; CTRP2 -0.876 2.9396 -0.9394 46.2086
NCI-H2228 GDSC1; GDSC2; CTRP2 -0.8609 4.6267 -1.1572 46.3845
IST-SL1 GDSC1; GDSC2 -0.7529 1.2174 -0.7717 30.7389
Calu-6 GDSC1; GDSC2; CTRP2 -0.7512 2.146 -0.7663 45.3064
HCC44 GDSC1; GDSC2; CTRP2 -0.7338 2.2392 -0.7518 45.197
HCC78 GDSC1; GDSC2; CTRP2 -0.7308 2.3483 -0.7529 45.1853
RERF-LC-MS GDSC1; GDSC2; CTRP2 -0.6811 2.5722 -0.7123 42.0899
NCI-H847 GDSC1; GDSC2 -0.678 0.688 -0.68 38.761
NCI-H358 GDSC1; GDSC2; CTRP2 -0.666 2.4683 -0.6916 44.7631
NCI-H1339 CTRP2 -0.6436 1.6421 -0.6469 44.5652
NCI-H209 GDSC1; GDSC2; CTRP2 -0.6261 4.0917 -0.8101 44.7747
HOP-92 GDSC1; GDSC2; CTRP2 -0.6243 4.0751 -0.8056 44.7591
NCI-H2810 GDSC1; GDSC2 -0.6161 2.9977 -0.8917 30.6769
NCI-H23 GDSC1; GDSC2; CTRP2 -0.601 1.8957 -0.6075 44.2896
NCI-H446 GDSC1; GDSC2; CTRP2 -0.591 1.5473 -0.5931 44.2119
HCC1588 CTRP2 -0.5825 2.0019 -0.5909 44.1713
LXF 289 GDSC1; GDSC2; CTRP2 -0.58 1.3996 -0.5812 44.1362
NCI-H3122 GDSC1; GDSC2 -0.5566 2.3571 -0.6918 38.1479
NCI-H2170 GDSC1; GDSC2; CTRP2 -0.5487 2.7728 -0.5868 44.0134
T3M-10 CTRP2 -0.5314 1.598 -0.5336 43.8154
DMS 273 GDSC1; GDSC2; CTRP2 -0.5137 2.2145 -0.5263 43.7241
NCI-H2369 GDSC1; GDSC2 -0.5115 5.7133 -1.6919 40.8012
NCI-H720 GDSC1; GDSC2 -0.5078 2.3592 -0.6396 37.6703
ABC-1 GDSC1; GDSC2 -0.4828 2.5424 -0.6463 29.258
COR-L51 CTRP2 -0.469 2.2534 -0.4818 43.4273
LC-2/ad GDSC1; GDSC2 -0.4365 2.8657 -0.6647 29.158
Lu-99A GDSC1; GDSC2 -0.4286 2.6089 -0.6008 37.081
COR-L279 GDSC1; GDSC2; CTRP2 -0.416 3.3431 -0.4926 43.2213
NCI-H250 GDSC2 -0.3775 4.6502 -2.0702 21.3635
NCI-H1975 GDSC1; GDSC2 -0.3521 2.4861 -0.4943 36.2293
NCI-H1963 GDSC1; GDSC2 -0.3047 1.5647 -0.3283 35.2474
NCI-H810 GDSC1; GDSC2; CTRP2 -0.2821 1.423 -0.2826 42.1497
NCI-H1651 GDSC1; GDSC2; CTRP2 -0.2705 3.342 -0.3396 42.2483
NCI-H2171 GDSC2; CTRP2 -0.2324 1.7192 -0.2339 39.2112
SBC-5 GDSC1; GDSC2; CTRP2 -0.196 2.4158 -0.2084 41.6109
NCI-H2196 GDSC2; CTRP2 -0.1933 2.9881 -0.2317 39.0728
NCI-H292 GDSC1; GDSC2; CTRP2 -0.1741 2.9902 -0.2119 38.9515
COR-L95 GDSC1; CTRP2 -0.1618 4.0876 -0.312 41.7214
NCI-H1781 GDSC1; GDSC2 -0.1375 3.2541 -0.4352 34.8524
COLO 668 GDSC1; GDSC2; CTRP2 -0.1345 2.4064 -0.1455 41.198
SW1271 GDSC1; GDSC2; CTRP2 -0.0794 4.3693 -0.2672 41.2713
Lu-134-A GDSC1; GDSC2 -0.067 3.3773 -0.3918 26.7697
NCI-H1355 GDSC1; GDSC2; CTRP2 -0.061 7.0174 -0.9077 42.3684
NCI-H2085 GDSC1; GDSC2; CTRP2 -0.0378 2.305 -0.0449 40.5426
HCC95 CTRP2 -0.0377 2.8224 -0.0618 40.5915
NCI-H1048 GDSC1; GDSC2 -0.0336 1.8046 -0.0634 32.6526
SBC-3 GDSC1; GDSC2 -0.0103 1.5532 -0.0233 32.346
NCI-H322 CTRP2 -0.0036 1.9039 -0.0052 40.2975
NCI-H1436 GDSC1; GDSC2 0.0059 2.7356 -0.1554 25.5806
NCI-H82 GDSC1; GDSC2 0.03 2.0295 -0.0177 32.1228
HCC2279 CTRP2 0.0369 4.3998 -0.1471 40.5085
PaCa-3 GDSC1; GDSC2 0.0729 3.2499 -0.2045 32.7803
UMC-11 GDSC1; GDSC2 0.0736 2.2451 0.0024 31.814
NCI-H1792 GDSC1; GDSC2; CTRP2 0.1002 1.8015 0.0994 39.6038
NCI-H2009 GDSC1; GDSC2; CTRP2 0.1289 3.7371 0.0417 39.6611
SW1573 GDSC1; GDSC2 0.1326 2.6681 -0.0045 31.5591
NCI-H2030 GDSC1; GDSC2; CTRP2 0.1332 3.4731 0.0722 37.1035
NCI-H1437 GDSC1; GDSC2 0.1594 2.5367 0.0489 24.2277
NCI-H196 GDSC1; GDSC2; CTRP2 0.1606 4.0891 0.0322 39.5622
NCI-H1623 GDSC1; GDSC2; CTRP2 0.2148 2.2631 0.2113 38.849
Lu-135 GDSC1; GDSC2 0.2366 2.8229 0.0768 30.6669
COR-L32 GDSC1; GDSC2 0.2441 4.9249 -0.579 26.4267
NCI-H748 GDSC2 0.2603 2.2336 -0.3055 9.7256
A-549 GDSC1; GDSC2; CTRP2 0.2649 2.9862 0.2418 38.5762
NCI-H2804 GDSC1; GDSC2 0.2886 3.5477 -0.0527 24.1765
Lu-65 GDSC1; GDSC2; CTRP2 0.2924 2.8537 0.2758 38.3733
NCI-H1373 CTRP2 0.2926 4.7902 0.0599 38.9691
NCI-H841 GDSC1; GDSC2; CTRP2 0.2999 3.3954 0.253 38.415
NCI-H460 GDSC1; GDSC2; CTRP2 0.3226 4.967 0.0578 36.4919
NCI-H1299 GDSC1; GDSC2; CTRP2 0.3305 3.6444 0.2637 38.2706
NCI-H1694 GDSC1; GDSC2; CTRP2 0.3597 3.5113 0.3062 38.0379
NCI-H1581 GDSC1; GDSC2; CTRP2 0.3892 3.0884 0.3648 37.7534
NCI-H1648 GDSC1; GDSC2 0.3914 2.9301 0.2216 29.2254
HCC1195 CTRP2 0.4048 5.4947 0.0307 38.6004
NCI-H510A GDSC1; GDSC2 0.4118 2.3637 -0.2178 8.7334
NCI-H520 GDSC1; GDSC2; CTRP2 0.4359 4.5071 0.2645 37.8715
RERF-LC-KJ GDSC1; GDSC2 0.4404 4.7651 -0.308 31.4545
NCI-H146 GDSC1; GDSC2; CTRP2 0.4785 2.9602 0.4623 34.8164
NCI-H2227 GDSC1; GDSC2 0.483 3.1187 0.2767 22.1744
SBC-1 GDSC1; GDSC2 0.4847 2.2477 0.4392 21.5271
COR-L88 GDSC1; GDSC2; CTRP2 0.4897 4.9953 0.2332 37.7524
NCI-H2347 GDSC1; GDSC2 0.5124 3.4489 0.2201 28.6654
NCI-H290 GDSC1; GDSC2 0.5574 2.6063 0.4659 21.159
LK-2 GDSC1; GDSC2 0.6059 2.4933 0.5361 26.6573
LCLC-103H GDSC1; GDSC2; CTRP2 0.6202 2.9842 0.6064 36.1821
NCI-H3255 GDSC1; GDSC2 0.6205 2.3129 0.5757 20.5026
NCI-H1915 GDSC1; GDSC2; CTRP2 0.6356 4.2237 0.1026 24.1699
ChaGo-K-1 GDSC1; GDSC2; CTRP2 0.6961 2.6144 0.6923 33.4188
NCI-H650 GDSC1; GDSC2; CTRP2 0.7119 3.2676 0.6884 35.6026
LC-1/sq-SF CTRP2 0.7247 4.6274 0.5553 35.9677
HCC2935 CTRP2 0.7268 4.6213 0.5585 35.9507
NCI-H1693 GDSC1; GDSC2 0.7366 5.3446 -0.2267 29.7428
RERF-LC-Ad2 CTRP2 0.7759 3.9686 0.7005 35.3419
Ms-1 GDSC1; GDSC2 0.7794 2.988 0.6308 25.3746
NCI-H2087 GDSC1; GDSC2; CTRP2 0.7801 4.2864 0.6664 35.4331
NCI-H2373 GDSC1; GDSC2 0.7961 6.947 -0.8668 32.08
NCI-H513 GDSC1; GDSC2 0.8178 3.4044 0.5662 25.5292
NCI-H322M GDSC1; GDSC2 0.828 5.3202 -0.1208 28.86
RERF-LC-Ad1 CTRP2 0.8405 3.3347 0.8176 34.7443
NCI-H526 GDSC1; GDSC2; CTRP2 0.8912 2.6244 0.889 34.3387
COR-L303 GDSC2 0.9027 3.1844 -0.1743 7.0181
KNS-62 GDSC1; GDSC2; CTRP2 0.9052 4.6748 0.7417 34.7595
NCI-H1573 GDSC1; GDSC2; CTRP2 0.9118 4.8162 0.7242 34.7901
COR-L311 GDSC2 0.9235 2.7878 0.8286 24.5568
NCI-H1666 GDSC1; GDSC2; CTRP2 0.9351 4.5694 0.7909 34.5019
HCC15 GDSC1; GDSC2; CTRP2 0.9371 3.6285 0.8998 34.1481
NCI-H1105 GDSC1; GDSC2; CTRP2 0.9398 2.7907 0.9359 31.8973
NCI-H1869 GDSC1; GDSC2; CTRP2 0.9461 3.9486 0.8821 34.1749
DMS 454 CTRP2 0.9761 14.2225 -2.7743 41.1092
NCI-H2722 GDSC1; GDSC2 0.9813 4.3958 0.4108 25.6038
IST-SL2 GDSC1; GDSC2 1.0039 4.1902 0.5114 19.4498
HCC2108 CTRP2 1.0136 4.2513 0.9197 33.8224
NCI-H1838 GDSC1; GDSC2; CTRP2 1.0283 5.5288 0.7018 34.4454
HCC1438 CTRP2 1.1148 3.2293 1.1034 32.8798
NCI-H596 GDSC1; GDSC2 1.1261 3.5788 0.8508 22.6817
NCI-H1385 CTRP2 1.1445 7.9625 0.0732 35.7389
Calu-3 GDSC1; GDSC2; CTRP2 1.1716 4.1989 1.0936 32.7208
NCI-H2081 GDSC1; GDSC2; CTRP2 1.2005 4.076 1.1374 30.4541
NCI-H2405 GDSC1; GDSC2; CTRP2 1.2115 4.1785 1.1382 32.4402
NCI-H522 GDSC1; GDSC2; CTRP2 1.2219 4.94 1.0366 32.7352
NCI-H1563 GDSC1; GDSC2; CTRP2 1.2482 6.2874 0.7418 33.5558
SHP-77 GDSC1; GDSC2; CTRP2 1.2522 2.584 1.2517 31.9278
DMS 114 GDSC1; GDSC2; CTRP2 1.2683 4.071 1.2094 32.0149
NCI-H835 GDSC1; GDSC2 1.2744 3.4996 1.0365 21.0541
NCI-H69 GDSC1; GDSC2; CTRP2 1.292 3.6364 1.2674 31.743
HCC366 GDSC1; GDSC2; CTRP2 1.3351 4.8046 1.1826 29.8959
NCI-H2869 GDSC1; GDSC2 1.3457 6.7531 -0.2287 21.5438
NCI-H1993 GDSC1; GDSC2 1.3624 4.089 0.934 21.2237
NCI-H2444 GDSC1; GDSC2; CTRP2 1.3803 6.2716 0.8905 30.6622
DMS 53 GDSC1; GDSC2; CTRP2 1.4012 6.1238 0.9553 32.3812
NCI-H2106 CTRP2 1.4096 4.7526 1.2715 31.337
EBC-1 GDSC1; GDSC2; CTRP2 1.4257 4.7236 1.2933 31.2114
NCI-H1435 GDSC1; GDSC2; CTRP2 1.4826 2.9061 1.4815 30.3948
NCI-H2126 CTRP2 1.5856 4.8241 1.4491 30.1628
NCI-H2141 GDSC1; GDSC2; CTRP2 1.6376 5.7679 1.3077 30.4615
EKVX GDSC1; GDSC2; CTRP2 1.6539 4.2409 1.5987 27.5984
NCI-H187 GDSC1 1.6694 4.0991 1.2595 18.1743
NCI-H441 GDSC1; GDSC2; CTRP2 1.6799 5.5024 1.4176 29.958
LK2 CTRP2 1.6839 2.3803 1.6839 29.0501
DMS 79 GDSC1; GDSC2 1.7276 4.682 1.0863 14.6957
NCI-H740 GDSC2 1.7373 7.7079 -1.7611 13.711
NCI-H2803 GDSC1; GDSC2 1.7513 3.4624 1.5676 12.5527
NCI-H2172 GDSC1; GDSC2; CTRP2 1.793 6.1152 1.3852 27.8639
NCI-H2818 GDSC1; GDSC2 1.8115 8.271 -0.5018 26.601
IA-LM GDSC1; GDSC2; CTRP2 1.8357 5.222 1.6469 28.6777
NCI-H1793 GDSC1; GDSC2; CTRP2 1.9297 10.6684 -0.2058 33.811
RERF-LC-A1 CTRP2 1.9544 4.1316 1.923 27.3533
Calu-1 CTRP2 1.9644 7.678 1.059 30.2016
NCI-H1770 GDSC1; GDSC2 1.9803 3.224 1.8833 10.4779
NCI-H2342 GDSC1; GDSC2; CTRP2 2.1054 5.5872 1.8613 27.0771
BEN GDSC1; GDSC2; CTRP2 2.2637 5.8367 1.9733 24.5573
NCI-H1688 GDSC1; GDSC2 2.2736 7.0867 0.5077 20.0842
NCI-H2066 GDSC1; GDSC2 2.2822 6.1046 0.9913 17.3793
HCC1171 CTRP2 2.3295 9.6809 0.636 30.3475
NCI-H2591 GDSC1; GDSC2 2.4095 5.2486 1.5223 13.8525
NCI-H2595 GDSC1; GDSC2 2.4546 5.7424 1.33 14.8245
NCI-H1092 GDSC1; GDSC2; CTRP2 2.4702 5.4492 2.2886 24.435
COR-L321 GDSC1; GDSC2 2.6259 5.0309 1.8355 8.7384
NCI-H2029 GDSC1; GDSC2; CTRP2 2.6269 7.9275 1.6729 24.5377
Lu-165 GDSC1; GDSC2 2.6938 8.713 0.0865 20.8533
NCI-H2291 GDSC1; GDSC2; CTRP2 2.9238 9.372 1.3828 24.704
NCI-H1836 GDSC1; GDSC2 2.9743 7.6537 0.86 12.4343
Lu-139 GDSC1 3.0908 5.9017 1.8347 9.7561
HCC1833 CTRP2 3.1237 10.933 0.8814 27.3101
NCI-H226 GDSC1; GDSC2; CTRP2 3.1508 9.1474 1.7143 24.4719
NCI-H889 CTRP2 3.2665 6.6131 2.8404 20.0218
NCI-H1304 GDSC1 3.3751 6.0833 1.9853 8.0192
NCI-H1395 CTRP2 4.0832 8.3611 3.0156 17.0875
NCI-H2135 GDSC1; GDSC2 5.0446 7.1179 2.5948 1.0609
NCI-H345 GDSC1; GDSC2 5.4642 12.6915 0.28 10.1617
Hs 888.Lu CTRP2 -0.5697 5.9142 -1.1386 44.9397
⏷ Show the Full List of 223 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 0.4666 3.7784 0.0702 29.6061
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -3.5372 2.8713 -3.7478 61.7401
COV434 CTRP2 -2.7256 4.4755 -3.1483 56.8485
SNU-119 CTRP2 -2.4453 0.6467 -2.452 56.491
COV362 CTRP2 -2.298 2.0877 -2.3581 55.3171
Caov-3 GDSC2; CTRP2 -1.9759 10.0032 -4.0366 50.0608
IGROV-1 GDSC1; GDSC2; CTRP2 -1.9206 2.7443 -2.018 52.889
OVCAR-8 GDSC1; GDSC2; CTRP2 -1.5881 -0.3333 -1.5881 50.8489
TOV-21G GDSC1; GDSC2 -1.5127 1.2492 -1.5653 39.537
DOV13 GDSC1; GDSC2; CTRP2 -1.3467 0.5446 -1.3471 49.2411
ES-2 GDSC1; GDSC2 -1.295 1.0687 -1.3241 37.6882
SNU-8 CTRP2 -1.2758 1.8537 -1.2924 48.7811
JHOS-4 GDSC1; GDSC2 -1.168 3.0654 -1.5105 34.9878
OVCAR-4 GDSC1; GDSC2; CTRP2 -1.0849 3.7217 -1.2468 47.6538
OVCAR-5 GDSC1; GDSC2; CTRP2 -1.0644 3.4565 -1.1904 47.4944
SK-OV-3 GDSC1; GDSC2; CTRP2 -1.0353 3.5778 -1.1747 47.3213
Caov-4 GDSC1; GDSC2 -1.0075 2.8631 -1.2859 36.258
JHOC-5 CTRP2 -0.9237 3.5028 -1.0467 46.5928
OC 314 GDSC1; GDSC2; CTRP2 -0.9183 1.3352 -0.9206 46.3918
TYK-nu GDSC1; GDSC2; CTRP2 -0.6379 2.7274 -0.6764 44.6032
OVK18 GDSC1; GDSC2; CTRP2 -0.6308 3.8715 -0.7828 42.045
A2780 GDSC1; GDSC2; CTRP2 -0.5954 1.725 -0.5993 44.2458
OVTOKO GDSC1; GDSC2; CTRP2 -0.4103 4.1392 -0.586 43.3801
TOV-112D GDSC1; GDSC2; CTRP2 -0.4022 3.4388 -0.4875 43.1493
OAW42 GDSC1; GDSC2; CTRP2 -0.2041 2.0561 -0.2088 41.6429
ES2 CTRP2 -0.188 4.6834 -0.4398 42.1045
JHOS-2 GDSC1; GDSC2; CTRP2 -0.1531 2.3628 -0.1633 38.7422
OVISE GDSC1; GDSC2; CTRP2 -0.0725 4.4667 -0.276 41.2618
ONCO-DG-1 CTRP2 -0.0141 3.4219 -0.0777 40.5427
HEY A8 CTRP2 0.1267 3.8386 0.0279 39.7069
COV644 CTRP2 0.1563 4.0324 0.0353 39.5707
MCAS CTRP2 0.1961 3.1321 0.1629 39.064
EFO-27 GDSC1; GDSC2; CTRP2 0.2384 5.1719 -0.0768 37.1367
FU-OV-1 GDSC1; GDSC2; CTRP2 0.2947 3.8018 0.21 38.559
OVCAR-3 GDSC1; GDSC2 0.3567 4.1696 -0.1796 26.418
EFO-21 GDSC1; GDSC2; CTRP2 0.4212 3.9811 0.3235 37.7602
JHOM-1 CTRP2 0.6278 4.1753 0.5188 36.4273
RMG-I GDSC1; GDSC2; CTRP2 0.6393 5.8502 0.1975 37.2769
OV-90 GDSC1; GDSC2; CTRP2 0.76 7.0356 -0.0208 37.362
OAW28 GDSC1; GDSC2; CTRP2 0.7917 5.8195 0.3717 36.2444
SNU-840 CTRP2 1.0321 4.9573 0.8282 34.0474
Kuramochi GDSC1; GDSC2; CTRP2 1.2558 5.4537 0.9671 32.8398
OV56 GDSC1; GDSC2; CTRP2 1.5152 5.0249 1.3379 30.7659
OV7 CTRP2 1.7205 3.3939 1.7153 28.8236
OVKATE GDSC1; GDSC2 2.0134 8.7703 -0.5572 22.5405
OVSAHO CTRP2 3.3645 8.4509 2.2357 21.9933
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -2.6791 1.8575 -2.7386 57.6773
H-STS CTRP2 -1.8194 0.13 -1.8197 52.3888
P-STS CTRP2 -1.2032 3.8674 -1.3947 48.4127
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -1.877 3.6849 -2.0893 52.5003
Yamato-SS CTRP2 -0.6903 6.0116 -1.2964 45.6815
Rh30 GDSC1; GDSC2 -5.4798 -1.0839 -5.5284 78.0713
A-204 GDSC1; GDSC2; CTRP2 -4.818 3.0845 -5.1529 66.9358
G-402 GDSC1; GDSC2; CTRP2 -3.098 4.9298 -3.6521 58.3721
KYM-1 GDSC1; GDSC2; CTRP2 -2.689 -0.6529 -2.6891 58.1764
STS-0421 GDSC1; GDSC2 -2.4108 0.3438 -2.4364 43.2195
EW-8 GDSC1; GDSC2 -2.0941 -0.8371 -2.0942 52.4704
BT-16 CTRP2 -1.8519 0.8556 -1.856 52.5946
Rh41 GDSC1; GDSC2; CTRP2 -1.69 -0.113 -1.69 51.5273
SK-UT-1 GDSC1; GDSC2; CTRP2 -1.4922 0.2274 -1.4923 50.2095
TE 617.T CTRP2 -1.4722 0.471 -1.4726 50.0768
RKN GDSC1; GDSC2; CTRP2 -1.2969 2.175 -1.327 48.9278
VA-ES-BJ GDSC1; GDSC2 -1.265 2.2629 -1.4396 44.8765
HT-1080 GDSC1; GDSC2; CTRP2 -1.2482 0.752 -1.2488 48.5852
Tm87-16 CTRP2 -1.2094 3.4947 -1.3493 48.4235
Hs 633.T GDSC1; GDSC2 -1.1026 1.1628 -1.1305 42.9688
SW982 GDSC1; GDSC2; CTRP2 -1.0221 2.2352 -1.0471 47.1151
TTC-709 CTRP2 -0.9315 3.4286 -1.0461 46.6332
Hs 729.T CTRP2 -0.3328 3.6225 -0.4341 42.7294
MES-SA GDSC1; GDSC2; CTRP2 -0.2065 1.7809 -0.2083 41.6497
MFH-ino GDSC1; GDSC2 -0.0464 3.7536 -0.4804 34.5688
TE 441.T GDSC2; CTRP2 0.0272 3.9458 -0.0909 37.9193
Rh18 GDSC1; CTRP2 0.2374 4.106 0.1118 39.0501
G-401 GDSC1; GDSC2; CTRP2 0.5396 2.4935 0.5359 36.6859
GCT GDSC1; GDSC2; CTRP2 0.5489 2.6967 0.5419 36.6347
SW872 GDSC1; GDSC2 0.5755 2.1055 0.5491 26.7365
RD GDSC1; GDSC2; CTRP2 0.9022 3.6736 0.8601 34.396
SK-LMS-1 GDSC1; GDSC2; CTRP2 1.3024 4.902 1.1305 32.1586
SW684 GDSC1; GDSC2 2.4997 4.7952 1.8235 11.7614
BT-12 CTRP2 2.9984 4.3641 2.9892 20.3236
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 0.5723 7.0736 -0.2372 38.5668
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 -2.2648 1.7275 -2.302 55.1824
MPP 89 GDSC1; GDSC2; CTRP2 -2.0887 1.2995 -2.1044 54.118
NCI-H2452 GDSC1; GDSC2; CTRP2 -1.2696 3.0447 -1.3621 48.7815
NCI-H28 GDSC1; GDSC2; CTRP2 -0.9386 1.998 -0.953 46.5479
NCI-H2052 GDSC1; GDSC2; CTRP2 0.2872 5.0216 0.0082 39.1199
IST-Mes1 GDSC1; GDSC2; CTRP2 0.8916 2.2869 0.8912 34.3299
JL-1 CTRP2 0.9078 2.9188 0.9011 34.2431
ACC-MESO-1 CTRP2 0.9612 3.5876 0.9277 33.9754
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2; CTRP2 0.5433 5.9517 0.066 37.9752
DU145 GDSC1; GDSC2; CTRP2 0.6089 3.8277 0.5389 36.434
NCI-H660 GDSC2 1.0408 2.5283 0.2696 4.0963
PC-3 GDSC1; GDSC2 1.5269 5.6874 0.4404 23.1964
VCaP GDSC1; GDSC2; CTRP2 1.5831 5.5989 1.2897 30.7004
22Rv1 GDSC1; GDSC2; CTRP2 2.0299 5.7059 1.7509 27.6975
PaCa-3 CTRP2 2.2565 6.3294 1.8293 26.7113
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -1.6842 0.0954 -1.6843 51.4886
A-253 GDSC1; GDSC2; CTRP2 0.3116 4.9988 0.0394 38.9459
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -1.0775 1.639 -1.1461 33.3656
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-601 CTRP2 -3.5739 4.2511 -4.0227 60.9021
HSC-39 GDSC1; GDSC2 -3.0842 -1.8675 -3.0842 62.059
OCUM-1 GDSC1; GDSC2; CTRP2 -2.6635 6.38 -3.5525 55.7654
TGBC11TKB GDSC1; GDSC2 -2.5888 -0.0785 -2.6017 57.0957
GSS CTRP2 -2.3493 -1.0917 -2.3493 55.9202
SNU-16 GDSC1; GDSC2; CTRP2 -2.3131 -0.6552 -2.3131 55.6781
SNU-668 CTRP2 -2.2112 -1.5724 -2.2112 54.9997
SNU-5 GDSC1; GDSC2; CTRP2 -2.0781 -0.2729 -2.0782 54.1122
HGC-27 GDSC1; GDSC2; CTRP2 -2.0756 0.9062 -2.0824 54.0633
NUGC-4 GDSC1; GDSC2; CTRP2 -1.9637 2.2628 -2.0227 53.217
SK-GT-2 GDSC1; GDSC2 -1.4565 0.9731 -1.4855 46.3646
HuG1-N CTRP2 -1.3694 3.5228 -1.5234 49.4323
SNU-620 CTRP2 -1.3617 -0.1518 -1.3617 49.3406
MKN1 GDSC1; GDSC2; CTRP2 -1.278 2.3328 -1.3157 55.8981
Hs 746.T GDSC1; GDSC2; CTRP2 -0.8125 3.6678 -0.949 45.8971
23132/87 GDSC1; GDSC2; CTRP2 -0.6229 2.7503 -0.6623 44.5057
SNU-216 CTRP2 -0.5631 2.4822 -0.5864 44.0766
KATO III GDSC1; GDSC2; CTRP2 -0.4742 3.6313 -0.5849 43.6705
MKN74 CTRP2 -0.3869 8.4662 -1.758 44.7834
LMSU CTRP2 -0.356 3.5752 -0.4533 42.8723
AGS GDSC1; GDSC2; CTRP2 -0.3496 2.4766 -0.3673 42.6461
NCI-N87 GDSC1; GDSC2; CTRP2 -0.2102 3.611 -0.303 41.9072
SNU-1 GDSC1; GDSC2; CTRP2 -0.2 2.3406 -0.2104 41.6317
RERF-GC-1B GDSC1; GDSC2 -0.0646 2.2452 -0.1453 33.1935
MKN45 GDSC1; GDSC2; CTRP2 0.02 9.282 -1.6298 43.0169
NUGC-3 GDSC1; GDSC2; CTRP2 0.077 4.0549 -0.0523 40.1128
Fu97 GDSC1; GDSC2; CTRP2 0.1189 6.1642 -0.4554 40.8266
SH-10-TC CTRP2 0.2119 3.1594 0.1776 38.9625
RF-48 GDSC1; GDSC2 0.2803 3.2268 0.028 30.6906
SCH GDSC1; GDSC2 0.3328 3.5584 -0.0077 23.8424
ECC12 GDSC2; CTRP2 0.4414 3.063 0.4198 35.0647
MKN7 GDSC1; GDSC2; CTRP2 0.5257 5.5456 0.1502 35.5487
TMK-1 GDSC1; GDSC2 0.5328 2.669 0.4282 21.3955
GCIY GDSC1; GDSC2 0.6817 3.4806 0.3958 27.0118
MKN28 GDSC1; GDSC2 0.7665 3.8576 0.3703 26.7565
IM95 GDSC1; GDSC2; CTRP2 0.8987 3.4263 0.8727 34.3672
ECC10 GDSC1; GDSC2; CTRP2 1.4255 5.3894 1.1662 31.6286
GSU CTRP2 1.4472 2.8302 1.4464 30.6297
KE-39 CTRP2 1.5239 7.4332 0.6724 32.8172
SNU-719 CTRP2 3.0675 8.7647 1.7935 24.4264
SNG-M GDSC1; GDSC2; CTRP2 -0.9771 3.1335 -1.0628 46.8937
SNU-685 CTRP2 0.2691 3.2023 0.2343 38.5837
SNU-1077 CTRP2 0.5096 3.5358 0.461 37.0276
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -4.0296 2.1267 -4.1794 64.6614
CGTH-W-1 GDSC1; GDSC2; CTRP2 -3.1373 1.8729 -3.2172 60.3028
FTC-238 CTRP2 -1.985 -0.9975 -1.985 53.4929
IHH-4 GDSC1; GDSC2 -1.4348 0.7246 -1.4502 46.1254
CAL-62 GDSC1; GDSC2; CTRP2 -1.3032 1.0775 -1.3056 48.9528
FTC-133 GDSC1; GDSC2; CTRP2 -1.19 2.3844 -1.2277 48.2321
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 -1.169 6.9221 -2.0839 46.0725
KMH-2 GDSC1; GDSC2 -1.1299 1.2686 -1.1663 33.641
8305C GDSC1; GDSC2; CTRP2 -0.7488 3.7966 -0.8984 45.5075
HTC-C3 GDSC1; GDSC2 -0.6192 2.9579 -0.8854 39.2142
K5 GDSC1; GDSC2 -0.5487 2.6287 -0.7352 38.2707
B-CPAP GDSC1; GDSC2; CTRP2 -0.3747 1.7617 -0.3774 42.7729
8505C GDSC1; GDSC2; CTRP2 -0.109 3.018 -0.1462 41.1009
TT GDSC1; GDSC2; CTRP2 -0.0378 4.7034 -0.2811 41.1259
ASH-3 GDSC1; GDSC2 -0.0364 2.3083 -0.1244 32.9561
BHT-101 GDSC1; GDSC2; CTRP2 0.6528 2.3252 0.6515 35.9241
WRO GDSC1; GDSC2 1.1067 5.414 0.1297 26.4766
TT2609-C02 GDSC1; GDSC2; CTRP2 1.206 3.2487 1.1958 32.2679
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1; GDSC2 -3.9996 -0.2909 -4.0431 54.9026
KON GDSC1; GDSC2 -3.6983 -0.2196 -3.7354 52.7508
BICR 10 GDSC1; GDSC2 -2.9163 -0.1449 -2.9341 60.0525
BICR 6 CTRP2 -2.8569 0.8792 -2.875 59.0546
HO-1-u-1 GDSC1; GDSC2 -2.5634 -0.4655 -2.5674 56.9489
JHU-022 GDSC1; GDSC2 -2.5129 1.4157 -2.6447 55.8248
BICR 18 CTRP2 -2.4496 1.857 -2.5004 56.2969
NCI-H3118 GDSC1; GDSC2 -2.4298 0.7867 -2.4862 55.3877
YD-8 CTRP2 -2.3737 1.7769 -2.417 55.8496
PCI-38 GDSC1 -2.3547 0.3106 -2.377 54.8518
SKN-3 GDSC1; GDSC2 -2.0588 2.026 -2.2539 51.879
HSC-4 GDSC1; GDSC2; CTRP2 -2.0277 2.6266 -2.1195 53.563
BB30-HNC GDSC1; GDSC2 -1.6238 1.3566 -1.6929 37.464
BICR 78 GDSC1; GDSC2 -1.3874 3.2217 -1.7905 46.3173
Detroit 562 GDSC1; GDSC2; CTRP2 -1.3355 0.3005 -1.3356 49.1663
YD-10B CTRP2 -1.1652 1.1663 -1.1676 48.0349
KOSC-2 GDSC1; GDSC2 -1.1637 1.448 -1.2171 33.9571
PCI-30 GDSC1; GDSC2 -1.0427 2.036 -1.1619 42.6829
JHU-011 GDSC1; GDSC2 -1.0307 1.5831 -1.0904 32.9812
PCI-15A GDSC1; GDSC2 -0.9189 1.381 -0.9547 32.0516
Ca9-22 GDSC1; GDSC2 -0.9043 1.1524 -0.9246 41.0294
PE/CA-PJ49 CTRP2 -0.7484 1.6307 -0.7524 45.2642
SAT [Human HNSCC] GDSC1; GDSC2 -0.637 3.2826 -0.9879 39.6563
CAL-27 GDSC1; GDSC2; CTRP2 -0.6351 2.6966 -0.6717 44.5811
BICR 16 CTRP2 -0.6345 5.0018 -0.9886 45.0646
HSC-3 GDSC1; GDSC2; CTRP2 -0.6319 2.5309 -0.6594 44.5412
UPCI-SCC-090 GDSC1; GDSC2 -0.5946 3.2491 -0.9326 39.2304
BB49-HNC GDSC1; GDSC2 -0.5631 2.6216 -0.7493 38.405
CAL-33 GDSC1; GDSC2; CTRP2 -0.5484 1.8625 -0.5538 43.937
JHU-029 GDSC1; GDSC2 -0.487 2.5628 -0.6549 29.3061
SCC-4 GDSC1; GDSC2; CTRP2 -0.4656 3.0746 -0.5213 43.5027
BICR 22 GDSC1; GDSC2; CTRP2 -0.4463 2.2852 -0.4597 43.2781
FaDu GDSC1; GDSC2; CTRP2 -0.3211 2.0617 -0.3272 42.426
LB771-HNC GDSC1; GDSC2 -0.2252 4.554 -0.9439 37.2172
BHY GDSC1; GDSC2; CTRP2 -0.1423 2.3484 -0.152 38.6733
SAS GDSC1; GDSC2 -0.0997 1.5026 -0.1129 33.2127
HO-1-N-1 GDSC1; GDSC2 -0.0901 2.0661 -0.149 33.3373
PCI-04B GDSC1; GDSC2 -0.0636 2.8417 -0.2537 26.2155
SNU-1214 CTRP2 -0.0593 2.9542 -0.0909 40.7559
DOK GDSC1; GDSC2 -0.0206 2.9056 -0.2212 33.3232
BICR 56 CTRP2 0.0206 4.2483 -0.1405 40.5598
OSC-19 GDSC1; GDSC2 0.0481 2.249 -0.0254 24.9208
SNU-1041 CTRP2 0.161 6.1185 -0.3967 40.5361
BICR 31 GDSC2; CTRP2 0.2027 2.4235 0.1965 36.5081
SNU-1076 CTRP2 0.2384 3.211 0.2019 38.7929
HSC-2 GDSC1; GDSC2; CTRP2 0.2577 2.0346 0.2565 38.5557
OSC-20 GDSC1; GDSC2 0.2729 3.2756 0.0069 30.826
PE/CA-PJ34 (clone C12) CTRP2 0.3166 2.4807 0.3107 38.1784
SNU-46 CTRP2 0.3413 4.0305 0.2324 38.3198
SCC-25 GDSC1; GDSC2; CTRP2 0.397 3.2652 0.363 35.3795
SCC-15 GDSC1; GDSC2 0.5555 4.2849 -0.0058 29.5534
SNU-899 CTRP2 0.661 2.5157 0.6582 35.8742
SCC-9 GDSC1; GDSC2; CTRP2 0.8026 3.6727 0.7562 35.0724
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 0.8104 2.6537 0.8071 32.7035
PE/CA-PJ41 (clone D2) CTRP2 1.0996 3.855 1.0519 33.1005
SNU-1066 CTRP2 2.2703 12.6199 -0.7469 34.0135
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 -3.1186 -0.5088 -3.1197 60.9914
JMSU-1 CTRP2 -2.438 -0.9514 -2.438 56.5109
253J CTRP2 -2.419 -0.6859 -2.419 56.3832
VM-CUB-1 CTRP2 -1.4376 0.0382 -1.4377 49.8464
CAL-29 GDSC1; GDSC2; CTRP2 -1.3795 1.5551 -1.3898 49.463
BC-3C CTRP2 -1.2355 0.6454 -1.2358 48.5002
647V GDSC1; GDSC2; CTRP2 -0.9336 0.4384 -0.9336 46.4883
RT-112 GDSC1; GDSC2; CTRP2 -0.8989 2.204 -0.9194 46.2949
UM-UC-1 CTRP2 -0.5887 1.766 -0.5931 44.2023
BFTC-905 GDSC1; GDSC2; CTRP2 -0.5313 0.9269 -0.5314 43.8088
KU-19-19 GDSC1; GDSC2; CTRP2 -0.5148 3.9708 -0.6728 44.0199
TCCSUP GDSC1; GDSC2; CTRP2 -0.4201 2.943 -0.4643 43.1773
SW1710 GDSC1; GDSC2; CTRP2 -0.3968 2.5177 -0.4173 42.967
5637 GDSC1; GDSC2; CTRP2 -0.3103 1.5713 -0.3114 42.3394
J82 GDSC1; GDSC2; CTRP2 -0.1246 2.9336 -0.1573 41.1924
639V GDSC1; GDSC2; CTRP2 0.0487 2.9004 0.0233 40.0208
253J-BV CTRP2 0.0612 9.5077 -1.6743 42.9118
SW780 GDSC1; GDSC2 0.3099 2.9445 0.1296 30.0609
HT-1376 GDSC1; GDSC2; CTRP2 0.4276 4.4437 0.2657 37.9
SCaBER CTRP2 0.553 2.4725 0.5497 36.5952
T24 GDSC1; GDSC2; CTRP2 0.5835 2.8341 0.5736 34.1412
UM-UC-3 GDSC1; GDSC2; CTRP2 0.6898 3.459 0.6543 35.7885
RT-4 GDSC1; GDSC2; CTRP2 1.2049 5.4447 0.9137 33.1821
HT-1197 GDSC1; GDSC2; CTRP2 1.5477 5.1494 1.3492 30.6211
KMBC-2 CTRP2 1.769 5.3989 1.5376 29.2648
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SKN GDSC1; GDSC2 -3.0673 1.7551 -3.294 59.7485
NEC8 GDSC1; GDSC2 -2.7014 -1.6099 -2.7014 58.3538
PWR-1E GDSC1; GDSC2 -2.6644 -0.9545 -2.6651 57.9708
Ca Ski GDSC1; GDSC2 -2.0222 0.5831 -2.0481 51.7294
TC-YIK GDSC1; GDSC2 -2.0002 -0.3625 -2.0014 51.558
SW756 GDSC1; GDSC2 -1.7156 49.6748 -24.1757 49.8686
C-4-I GDSC1; GDSC2 -1.653 2.4029 -1.8868 48.4051
NCC-IT GDSC2 -1.5318 2.1905 -1.7146 48.8371
C-33 A GDSC1; GDSC2 -1.3327 1.4665 -1.3971 45.2668
KGN GDSC1; GDSC2 -1.2689 5.3139 -2.3448 40.3326
HEY GDSC1; GDSC2 -1.2367 0.8427 -1.2518 44.2172
UWB1.289 GDSC1; GDSC2 -1.1627 3.2053 -1.541 35.0658
SiSo GDSC1; GDSC2 -1.1597 0.9542 -1.1778 43.4854
OVCA433 GDSC1; GDSC2 -1.1366 1.9584 -1.2507 33.9737
SW954 GDSC1; GDSC2 -1.1193 1.1103 -1.1445 33.5197
PEO1 GDSC1; GDSC2 -0.9729 4.8243 -1.8469 37.7904
HeLa GDSC1; GDSC2; CTRP2 -0.5643 1.4134 -0.5654 44.0312
JAR GDSC1; GDSC2 -0.5291 0.9935 -0.5344 29.0035
JHOS-3 GDSC1; GDSC2 -0.4354 3.377 -0.7937 29.6424
ACC-OV7 GDSC1; GDSC2 -0.3857 3.9251 -0.9038 29.871
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 -0.3486 2.7084 -0.5345 28.3374
OV17R GDSC1; GDSC2 -0.3474 3.7993 -0.8224 29.4287
BPH-1 GDSC1; GDSC2 -0.3344 3.0841 -0.606 36.5895
OVMIU GDSC1; GDSC2 -0.2473 3.0452 -0.5013 30.0903
NT2-D1 GDSC1; GDSC2 0.0184 1.724 -0.0034 32.1104
CAL-39 GDSC1; GDSC2 0.0498 2.0941 -0.0038 31.9594
HT-3 GDSC1; GDSC2 0.0529 3.2423 -0.2243 32.9689
PA-1 GDSC1; GDSC2 0.0567 1.4659 0.0488 26.6071
JEG-3 GDSC1; GDSC2 0.0804 1.8704 0.0504 24.5103
DoTc2 4510 GDSC1; GDSC2 0.1009 2.2119 0.0359 31.5206
OVCA420 GDSC1; GDSC2 0.1595 3.8554 -0.2885 27.6218
ME-180 GDSC1; GDSC2 0.4995 4.1995 -0.0358 29.9537
MS751 GDSC1; GDSC2 0.6685 4.5924 0.0017 29.0018
DSH1 GDSC1; GDSC2 0.7151 3.2992 0.4832 26.418
SW962 GDSC1; GDSC2 0.7676 3.1738 0.5734 19.987
SKG-IIIa GDSC1; GDSC2 0.7738 3.6601 0.4419 26.3614
HEC-1 GDSC1; GDSC2 0.7892 3.4326 0.5269 25.8594
LB831-BLC GDSC1; GDSC2 1.4172 3.6069 1.159 19.7828
SiHa GDSC1; GDSC2 1.4941 4.1977 1.0345 20.1293
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7713).
2 Clinical pipeline report, company report or official report of AstraZeneca (2009).
3 Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity. Toxicol Sci. 2013 Oct;135(2):402-13. doi: 10.1093/toxsci/kft167. Epub 2013 Jul 28.