Details of the Drug

General Information of Drug (ID: DM1S5UO)

Drug Name
GSK4112
Synonyms SR6452; GSK-4112
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 396.9
Logarithm of the Partition Coefficient (xlogp) 4.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C18H21ClN2O4S
IUPAC Name
tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]acetate
Canonical SMILES
CC(C)(C)OC(=O)CN(CC1=CC=C(C=C1)Cl)CC2=CC=C(S2)[N+](=O)[O-]
InChI
InChI=1S/C18H21ClN2O4S/c1-18(2,3)25-17(22)12-20(10-13-4-6-14(19)7-5-13)11-15-8-9-16(26-15)21(23)24/h4-9H,10-12H2,1-3H3
InChIKey
WYSLOKHVFKLWOU-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
50905018
TTD ID
D07IZG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
V-erbA-related protein 1 (NR1D1) TTAD1O8 NR1D1_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 149 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 6.3091 8.2859 5.1359 3.3373
MEC1 CTRP2 7.7435 11.0158 4.7914 2.751
JM1 CTRP2 5.9948 7.3568 5.3465 3.0308
BDCM CTRP2 0.6277 56.159 -23.6587 47.9504
HuT 78 CTRP2 3.4919 8.6749 2.2712 21.5118
EoL-1 CTRP2 3.7692 5.6427 3.6584 15.5386
KMS-12-BM CTRP2 4.3536 7.2732 3.7625 13.4502
NU-DHL-1 CTRP2 4.642 7.4578 3.9852 11.808
KMS-11 CTRP2 4.7217 9.3576 3.1882 14.8071
SUP-T11 CTRP2 4.7617 6.4237 4.5253 9.3943
TALL-1 [Human adult T-ALL] CTRP2 4.7713 12.0602 1.9192 19.6154
M-07e CTRP2 4.7824 9.1568 3.3426 14.039
MOLT-3 CTRP2 5.0323 8.1165 4.0788 10.4478
Pfeiffer CTRP2 5.0397 7.6094 4.3221 9.4449
HH [Human lymphoma] CTRP2 5.3285 7.3098 4.7477 7.0103
SEM CTRP2 5.3339 6.9158 4.9328 6.2533
GA-10 CTRP2 5.3367 6.1094 5.2533 5.009
Mino CTRP2 5.382 8.7166 4.1228 9.4526
KMS-34 CTRP2 5.3929 10.1182 3.442 12.2468
ALL-SIL CTRP2 5.6485 8.7323 4.3577 7.8924
Daudi CTRP2 5.6576 6.8125 5.3043 3.9478
OPM-2 CTRP2 5.6717 7.2193 5.1234 4.6565
NCI-H929 CTRP2 5.6943 6.8448 5.3249 3.7755
697 CTRP2 5.6997 7.1348 5.1907 4.3142
MV4-11 CTRP2 5.7232 7.6844 4.9434 5.2877
EB1 CTRP2 5.8076 7.7891 4.9676 5.0047
SK-MM-2 CTRP2 5.847 11.3748 3.213 12.2417
NU-DUL-1 CTRP2 5.929 8.0734 4.9322 4.9023
SET-2 CTRP2 5.9559 6.6985 5.6409 1.8748
Ri-1 CTRP2 5.9643 7.7419 5.128 4.0092
OCI-AML-3 CTRP2 5.968 6.789 5.6067 1.9928
SUP-T1 CTRP2 5.9819 7.2646 5.3814 2.9096
DEL CTRP2 6.0544 7.709 5.2204 3.4442
KHM-1B CTRP2 6.065 8.7712 4.6981 5.6193
WSU-DLCL2 CTRP2 6.0766 6.8783 5.654 1.5801
Toledo CTRP2 6.1405 7.8371 5.2268 3.2557
AML-193 CTRP2 6.1934 8.7125 4.8324 4.8141
MOLP-8 CTRP2 6.2686 13.3229 2.5903 13.9068
MHH-CALL-3 CTRP2 6.3044 8.2684 5.141 3.3241
THP-1 CTRP2 6.3243 13.782 2.4063 14.5117
L-1236 CTRP2 6.3545 10.0528 4.2924 6.7858
U-937 CTRP2 6.4105 9.4126 4.6548 5.1712
ST486 CTRP2 6.5989 9.0994 4.9507 3.6311
BV-173 CTRP2 6.5996 9.8351 4.5895 5.1237
MHH-CALL-4 CTRP2 6.6237 8.2025 5.4016 1.7671
KMS-26 CTRP2 6.6602 8.0674 5.4884 1.3816
L-428 CTRP2 6.709 11.6937 3.7527 8.4088
KMS-27 CTRP2 6.7361 11.517 3.861 7.9155
KO52 CTRP2 6.7719 11.2214 4.0343 7.1389
DND-41 CTRP2 6.7906 14.2622 2.5396 13.1343
RPMI-8226 CTRP2 6.7999 9.1297 5.0769 2.8188
SKM-1 CTRP2 6.8177 8.1948 5.5248 1.0671
Karpas-620 CTRP2 6.8592 8.338 5.4844 1.1695
L-540 CTRP2 6.8649 13.4386 3.0068 11.1694
P3HR-1 CTRP2 6.867 8.8408 5.2579 2.0147
KMS-20 CTRP2 6.9 12.0743 3.7094 8.2633
RCH-ACV CTRP2 6.9994 13.3772 3.1403 10.4044
Mono-Mac-1 CTRP2 7.0564 10.5104 4.5882 4.421
SU-DHL-1 CTRP2 7.1011 8.6023 5.5017 0.8787
PL21 CTRP2 7.1227 8.8114 5.4226 1.1254
KYO-1 CTRP2 7.1402 9.7969 4.9839 2.7334
SIG-M5 CTRP2 7.1595 11.4184 4.2204 5.7602
MOLT-16 CTRP2 7.1597 11.8227 4.0238 6.5603
Reh CTRP2 7.1736 9.3094 5.2293 1.7632
CA46 CTRP2 7.1787 10.5557 4.6496 4.0008
RPMI-6666 CTRP2 7.2272 13.191 3.4025 8.9736
HD-MY-Z CTRP2 7.251 10.7481 4.6061 4.0744
KMS-28BM CTRP2 7.2968 10.3409 4.8286 3.1382
KMS-18 CTRP2 7.2985 11.56 4.2489 5.4395
Ci-1 CTRP2 7.3116 8.103 5.7895 0.0701
MOLT-13 CTRP2 7.315 13.369 3.3795 8.9248
MOLP-2 CTRP2 7.3568 10.3998 4.839 3.0229
HPB-ALL CTRP2 7.4157 10.0079 5.0553 2.1386
NB4 CTRP2 7.4272 8.8104 5.574 0.4421
JVM-3 CTRP2 7.4354 9.9089 5.1114 1.9134
MC116 CTRP2 7.4589 8.3721 5.7495 0.0906
OCI-AML-5 CTRP2 7.4782 19.9334 0.2556 19.6807
MOLM-16 CTRP2 7.4842 9.275 5.4126 0.8567
TF-1 CTRP2 7.5022 10.5017 4.8816 2.6871
HEL 92.1.7 CTRP2 7.507 8.644 5.6706 0.1984
AMO1 CTRP2 7.5157 8.8172 5.6096 0.3163
K-562 CTRP2 7.5311 9.8175 5.2053 1.4892
SUP-M2 CTRP2 7.5844 8.9971 5.5701 0.3736
OCI-AML-2 CTRP2 7.5894 9.5342 5.3568 0.9487
SU-DHL-10 CTRP2 7.6016 8.7532 5.6678 0.1746
PF-382 CTRP2 7.6064 15.2452 2.6719 11.2345
L-363 CTRP2 7.6331 9.3123 5.4683 0.6001
HL-60 CTRP2 7.6377 8.7255 5.6914 0.1295
Jurkat CTRP2 7.6479 11.7502 4.3916 4.3917
MOLM-6 CTRP2 7.6538 11.1863 4.6589 3.3518
SU-DHL-4 CTRP2 7.6595 9.2593 5.5011 0.501
SUP-B15 CTRP2 7.6636 9.7786 5.2916 1.0938
BL-70 CTRP2 7.6645 8.5974 5.7454 0.0616
Karpas-299 CTRP2 7.669 10.7601 4.8635 2.5671
EM-2 CTRP2 7.6821 9.0417 5.5939 0.2824
SR CTRP2 7.6952 9.3536 5.48 0.5348
OCI-M1 CTRP2 7.6972 9.2561 5.5189 0.439
CMK CTRP2 7.6995 20.5154 0.1378 19.6413
KE-37 CTRP2 7.703 9.354 5.4834 0.5223
A3/Kawakami CTRP2 7.7268 8.7116 5.7285 0.0691
HuNS1 CTRP2 7.776 9.6144 5.4132 0.6627
JeKo-1 CTRP2 7.803 10.5459 5.0351 1.819
P31/FUJ CTRP2 7.8371 15.2796 2.8222 10.2936
RS4;11 CTRP2 7.8417 9.5896 5.4525 0.5264
SU-DHL-8 CTRP2 7.8437 9.174 5.6094 0.2015
P12-Ichikawa CTRP2 7.8541 9.155 5.6203 0.1813
HT CTRP2 7.8558 8.9636 5.6881 0.0912
KM-H2 CTRP2 7.8941 11.7171 4.5612 3.4385
REC-1 CTRP2 7.9053 10.0638 5.2922 0.9171
HEL CTRP2 7.9254 9.5182 5.5154 0.3477
Kasumi-2 CTRP2 7.9654 10.3937 5.1852 1.1927
OCI-Ly3 CTRP2 7.972 9.4895 5.5448 0.274
DB CTRP2 7.9854 9.915 5.3888 0.6088
Karpas-422 CTRP2 7.9992 10.3883 5.2042 1.1105
NCO2 CTRP2 8.0013 10.2576 5.2589 0.9486
MOTN-1 CTRP2 8.015 17.7291 1.7519 13.9512
NOMO-1 CTRP2 8.0497 9.5077 5.5685 0.2102
A4/Fukuda CTRP2 8.0538 9.4558 5.5885 0.1786
EJM CTRP2 8.0625 9.8233 5.4572 0.4139
KE-97 CTRP2 8.0694 9.5912 5.5459 0.2415
SUP-HD1 CTRP2 8.0897 11.8476 4.6181 3.0102
Ku812 CTRP2 8.1694 11.5314 4.804 2.2695
Ki-JK CTRP2 8.1736 9.8918 5.4771 0.3314
NALM-6 CTRP2 8.202 10.3653 5.3084 0.6949
MM1.S CTRP2 8.2474 9.5341 5.6317 0.0896
Raji CTRP2 8.2549 9.332 5.7019 0.0358
ME1 CTRP2 8.2565 9.6962 5.5791 0.1467
RL CTRP2 8.306 9.7782 5.5686 0.1501
Granta-519 CTRP2 8.3326 9.9496 5.518 0.2141
Kasumi-1 CTRP2 8.3769 10.5099 5.3286 0.5602
OCI-Ly19 CTRP2 8.3801 10.1276 5.4723 0.2738
HDLM-2 CTRP2 8.4123 17.3012 2.2465 11.5671
KMS-21-BM CTRP2 8.5023 10.0587 5.5425 0.1446
GDM-1 CTRP2 8.5212 10.7049 5.3152 0.5263
JURL-MK1 CTRP2 8.5225 10.1087 5.5325 0.1529
Namalwa CTRP2 8.5497 10.524 5.3943 0.3575
EHEB CTRP2 8.5503 10.6075 5.3638 0.4151
MOLM-13 CTRP2 8.5619 10.0593 5.5636 0.1115
Peer CTRP2 8.6483 15.4329 3.3024 7.2935
LP-1 CTRP2 8.6535 14.9491 3.5332 6.4132
CML-T1 CTRP2 8.7079 16.6858 2.7463 9.3012
RPMI-8402 CTRP2 8.8183 16.0013 3.1444 7.6657
OCI-Ly10 CTRP2 8.8838 10.9203 5.3806 0.2819
KMM-1 CTRP2 8.8908 11.1901 5.2851 0.4448
F-36P CTRP2 10.1852 23.1751 0.6359 14.3607
U266B1 CTRP2 10.4538 22.376 1.1962 12.279
KCL-22 CTRP2 11.3953 22.6288 1.6737 9.6212
LAMA-84 CTRP2 12.0278 29.0035 -0.9132 16.22
JJN-3 CTRP2 13.8866 33.1548 -1.6654 15.8662
⏷ Show the Full List of 149 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 6.6161 16.2529 1.4084 17.5857
TE8 CTRP2 7.0329 9.0363 5.2699 1.7698
TE-5 CTRP2 6.7547 10.1719 4.5385 5.083
KYSE-410 CTRP2 7.0792 10.4142 4.6501 4.1384
KYSE-510 CTRP2 7.3481 10.29 4.8847 2.858
TE-6 CTRP2 7.4142 9.9452 5.0827 2.04
KYSE-150 CTRP2 7.5554 10.7293 4.8094 2.8975
TE-4 CTRP2 7.7694 9.9466 5.2743 1.0666
OE19 CTRP2 7.8499 8.9605 5.687 0.0933
COLO 680N CTRP2 7.8866 9.4431 5.5276 0.3379
KYSE-30 CTRP2 7.9229 11.4726 4.69 2.9273
TE-9 CTRP2 7.9788 9.1994 5.6509 0.112
KYSE-450 CTRP2 7.9789 9.2439 5.6354 0.1309
KYSE-180 CTRP2 8.0686 9.6692 5.5172 0.2925
OE21 CTRP2 8.0748 9.9557 5.412 0.5087
OE33 CTRP2 8.079 9.9704 5.4081 0.5157
EC-GI-10 CTRP2 8.0861 10.2051 5.3195 0.7304
KYSE-520 CTRP2 8.176 10.6331 5.1891 1.0325
TE-10 CTRP2 8.3223 10.3697 5.359 0.5164
KYSE-70 CTRP2 8.3317 10.2253 5.4172 0.3905
TE-1 CTRP2 8.4578 10.2477 5.4589 0.2735
TE-11 CTRP2 8.6157 10.4498 5.4468 0.2498
KYSE-140 CTRP2 8.9715 11.3086 5.2737 0.4383
TE-14 CTRP2 9.1948 18.2812 2.3105 10.2153
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.5828 9.91 5.6212 0.0597
SNU-410 CTRP2 6.4351 10.5298 4.1184 7.3692
MIA PaCa-2 CTRP2 6.4913 8.0931 5.3643 2.1026
KP-4 CTRP2 6.7193 9.9107 4.6408 4.7178
PSN1 CTRP2 6.9784 10.1314 4.7172 4.0127
Panc 04.03 CTRP2 7.0017 9.0096 5.2633 1.8307
PaTu 8988s CTRP2 7.0953 10.0156 4.8515 3.3116
HPAF-II CTRP2 7.1429 11.3716 4.2315 5.7404
PaTu 8902 CTRP2 7.1538 8.5347 5.5572 0.6614
BxPC-3 CTRP2 7.2767 11.1469 4.4327 4.7316
Panc 10.05 CTRP2 7.3152 10.5932 4.7218 3.5315
SNU-213 CTRP2 7.4939 8.8421 5.5908 0.3681
DAN-G CTRP2 7.5662 9.43 5.3887 0.8694
SU.86.86 CTRP2 7.5773 9.2974 5.4484 0.6886
L3.3 CTRP2 7.5905 8.9028 5.6084 0.2882
PaTu 8988t CTRP2 7.6949 8.9757 5.6234 0.2223
CFPAC-1 CTRP2 7.8625 9.195 5.6091 0.1967
Capan-2 CTRP2 7.8744 12.9191 3.9864 5.6803
YAPC CTRP2 8.1035 9.2975 5.6616 0.081
TCC-Pan2 CTRP2 8.1116 9.6755 5.5318 0.2529
SUIT-2 CTRP2 8.1467 9.3295 5.6659 0.0715
Hs 766T CTRP2 8.1481 9.7693 5.512 0.2761
KP-2 CTRP2 8.1531 9.3834 5.6498 0.0854
QGP-1 CTRP2 8.1935 9.8825 5.4884 0.3036
Panc 05.04 CTRP2 8.194 9.5425 5.6098 0.1213
Panc 08.13 CTRP2 8.2004 9.961 5.4622 0.3504
Panc 02.03 CTRP2 8.2134 9.6739 5.5711 0.1663
HPAC CTRP2 8.3386 9.9444 5.5221 0.2065
HuP-T3 CTRP2 8.386 14.9842 3.3431 7.4889
PK-59 CTRP2 8.4016 10.8774 5.1959 0.8737
HuP-T4 CTRP2 8.4547 10.0126 5.5412 0.1552
PK-45H CTRP2 8.4628 9.9705 5.5587 0.1328
Capan-1 CTRP2 8.4897 10.2445 5.4723 0.2434
Panc 03.27 CTRP2 8.5083 10.201 5.4948 0.2054
KP-3 CTRP2 8.7165 10.4649 5.4791 0.1813
AsPC-1 CTRP2 9.0271 14.4336 3.9976 4.2589
SW1990 CTRP2 11.8995 31.4673 -2.1803 19.3296
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.2855 10.4318 5.3193 0.6715
WM266-4 CTRP2 5.5473 6.1449 5.4715 3.5816
Hs 895.T CTRP2 6.4593 8.4834 5.151 3.0265
Hs 852.T CTRP2 6.7296 8.6737 5.2476 2.2347
WM115 CTRP2 6.8577 8.4631 5.4268 1.3829
UACC-257 CTRP2 6.9095 9.1212 5.1534 2.3673
UACC-62 CTRP2 7.1233 9.3581 5.177 2.0144
SK-MEL-5 CTRP2 7.1561 10.9613 4.4395 4.8773
SK-MEL-28 CTRP2 7.1594 8.0764 5.7409 0.1859
Hs 934.T CTRP2 7.2076 8.8616 5.4463 0.9695
A2058 CTRP2 7.2755 8.6113 5.5841 0.5023
SK-MEL-30 CTRP2 7.3121 8.7713 5.5366 0.6115
Hs 940.T CTRP2 7.3632 9.3785 5.3057 1.3018
RPMI-7951 CTRP2 7.3722 8.9594 5.4884 0.7105
SK-MEL-31 CTRP2 7.382 9.0522 5.4548 0.804
RVH-421 CTRP2 7.3899 11.62 4.2826 5.1733
Hs 944.T CTRP2 7.4389 10.4625 4.861 2.839
HT-144 CTRP2 7.4502 11.8672 4.2049 5.3989
WT2-iPS CTRP2 7.5041 9.1922 5.4564 0.7135
HMCB CTRP2 7.5247 8.5827 5.6996 0.145
MeWo CTRP2 7.5332 11.111 4.6183 3.6556
SK-MEL-2 CTRP2 7.5388 10.6171 4.8509 2.7604
IPC-298 CTRP2 7.5785 8.8181 5.6351 0.2399
CJM [Human melanoma] CTRP2 7.5928 8.6373 5.7059 0.1196
A101D CTRP2 7.6114 10.1334 5.1109 1.7388
WM1799 CTRP2 7.7065 9.2025 5.5434 0.3787
MDA-MB-435S CTRP2 7.7548 9.2578 5.5428 0.3593
Hs 936.T CTRP2 7.7941 8.9512 5.67 0.1243
K029AX CTRP2 7.854 8.9881 5.6789 0.1017
Hs 294T CTRP2 7.8722 9.2556 5.5909 0.2241
IGR-37 CTRP2 7.9005 9.1739 5.631 0.1539
Hs 839.T CTRP2 7.9124 9.1068 5.6589 0.1147
COLO 792 CTRP2 7.9196 10.2281 5.2314 1.0861
SK-MEL-1 CTRP2 7.9361 9.6473 5.471 0.4381
SK-MEL-3 CTRP2 7.9528 9.4758 5.5422 0.2853
WM793 CTRP2 7.9604 9.244 5.6286 0.1438
COLO 829 CTRP2 8.0123 11.8789 4.5582 3.3148
Mel JuSo CTRP2 8.0394 9.7453 5.4771 0.3816
SK-MEL-24 CTRP2 8.0506 9.5437 5.5559 0.2305
Mel Ho CTRP2 8.0732 9.4421 5.6007 0.1569
IGR-1 CTRP2 8.1474 9.7714 5.5109 0.2781
IGR-39 CTRP2 8.1952 9.3344 5.6809 0.0541
LOX-IMVI CTRP2 8.2193 9.7213 5.5565 0.1853
COLO 741 CTRP2 8.2327 10.0971 5.4246 0.4133
A-375 CTRP2 8.25 9.7264 5.5661 0.165
G-361 CTRP2 8.2632 9.667 5.5917 0.1301
WM88 CTRP2 8.3937 10.2263 5.4417 0.3227
COLO 800 CTRP2 8.4848 9.8873 5.595 0.092
Hs 688(A).T CTRP2 8.6535 15.982 3.0456 8.2566
WM983B CTRP2 8.6652 11.0843 5.2315 0.649
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 5.8637 11.1432 3.3429 11.6756
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YN CTRP2 6.0611 7.9699 5.0955 3.9563
SK-N-BE(2) CTRP2 6.746 8.7548 5.2198 2.3227
Kelly CTRP2 6.8358 10.0271 4.6679 4.4254
SK-N-SH CTRP2 7.066 9.7008 4.9814 2.8382
IMR-32 CTRP2 7.2622 8.1755 5.7453 0.1441
SK-N-DZ CTRP2 7.5546 9.0789 5.5253 0.4964
CHP-126 CTRP2 7.6971 10.0267 5.2034 1.3489
SK-N-FI CTRP2 7.7113 11.0426 4.7599 2.9037
NB1 CTRP2 7.961 9.4752 5.5457 0.276
SK-N-AS CTRP2 8.2425 9.8059 5.5352 0.2111
MHH-NB-11 CTRP2 8.2645 9.8681 5.5213 0.2268
KP-N-SI9s CTRP2 8.2781 9.8056 5.5487 0.1827
NH-6 CTRP2 8.4393 10.1445 5.4889 0.231
CHP-212 CTRP2 8.7251 10.5426 5.455 0.2116
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 7.2737 10.153 4.9019 2.8834
HuH-28 CTRP2 7.4327 8.7634 5.5947 0.3884
HuCC-T1 CTRP2 7.5991 9.3454 5.4392 0.7003
SNU-308 CTRP2 7.7071 11.2503 4.6621 3.2762
SNU-478 CTRP2 7.7749 9.697 5.3795 0.755
SNU-1196 CTRP2 7.8301 12.7272 4.0483 5.4968
SNU-245 CTRP2 8.606 10.921 5.2688 0.5915
SNU-1079 CTRP2 8.6775 10.353 5.5039 0.1583
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 6.076 7.1062 5.5396 2.0615
SK-ES-1 CTRP2 6.2606 8.5794 4.9523 4.1899
Hs 822.T CTRP2 7.0924 7.9668 5.7545 0.1839
TC71 CTRP2 7.1193 11.5124 4.1462 6.1237
CADO-ES1 CTRP2 7.5243 9.4235 5.3706 0.9555
SK-N-MC CTRP2 7.7842 12.0175 4.3534 4.3657
SJSA-1 CTRP2 7.8275 9.6043 5.4405 0.5634
MG-63 CTRP2 8.1881 10.5628 5.2233 0.9282
CAL-78 CTRP2 8.2645 10.153 5.4168 0.417
HOS CTRP2 8.3354 10.0518 5.4824 0.27
SW1353 CTRP2 8.3936 9.7656 5.6044 0.0955
MHH-ES-1 CTRP2 8.3975 9.9104 5.5559 0.148
SaOS-2 CTRP2 8.5585 10.1177 5.5423 0.1348
Hs 888.T CTRP2 8.6037 23.4813 -0.6439 20.2953
G-292 clone A141B1 CTRP2 9.3168 12.7254 4.8778 1.1832
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 6.1693 7.7578 5.2894 2.9404
MDA-MB-453 CTRP2 6.1855 8.2948 5.0345 3.9806
HDQ-P1 CTRP2 6.2908 8.6634 4.9342 4.2123
AU565 CTRP2 6.6367 10.6546 4.2124 6.6277
CAL-148 CTRP2 6.7292 8.2746 5.4352 1.5014
KPL-1 CTRP2 6.7939 7.463 5.8206 0.1661
BT-20 CTRP2 6.8035 9.1686 5.0607 2.8789
HCC1419 CTRP2 6.944 9.039 5.2139 2.0884
MDA-MB-157 CTRP2 6.944 9.3317 5.0764 2.8191
HCC1569 CTRP2 7.0004 10.4873 4.5604 4.616
Hs 578Bst CTRP2 7.0836 10.3672 4.6757 4.0293
CAL-85-1 CTRP2 7.399 10.4152 4.8583 2.8976
HMC-1-8 CTRP2 7.4054 8.6331 5.6332 0.3124
ZR-75-30 CTRP2 7.4342 9.4322 5.3205 1.189
JIMT-1 CTRP2 7.6367 10.2953 5.0534 1.9154
SK-BR-3 CTRP2 7.7226 21.2376 -0.203 20.5624
HCC1954 CTRP2 7.7935 9.5481 5.4474 0.5641
MCF-7 CTRP2 7.8909 11.0842 4.8462 2.3952
T-47D CTRP2 7.912 12.9187 4.0112 5.5328
HCC1500 CTRP2 7.9235 9.7027 5.4443 0.5054
HCC1428 CTRP2 7.9385 9.4651 5.5404 0.2935
CAL-51 CTRP2 7.9586 10.0162 5.3366 0.7596
BT-474 CTRP2 8.0103 9.3491 5.6101 0.158
HCC2218 CTRP2 8.08 12.2811 4.415 3.7723
MDA-MB-468 CTRP2 8.148 12.3577 4.4209 3.6723
CAL-120 CTRP2 8.1574 9.5612 5.59 0.1531
HCC1395 CTRP2 8.1638 13.6557 3.8269 5.9185
CAMA-1 CTRP2 8.1772 9.5105 5.6148 0.1185
MDA-MB-231 CTRP2 8.1924 10.0537 5.4243 0.4302
ZR-75-1 CTRP2 8.2098 9.5452 5.6146 0.1132
BT-549 CTRP2 8.2282 9.9744 5.4685 0.3288
HCC38 CTRP2 8.3017 10.4488 5.3197 0.6162
MDA-MB-361 CTRP2 8.3721 11.9419 4.7351 2.3164
HCC1806 CTRP2 8.4207 9.8268 5.5931 0.1027
HCC202 CTRP2 8.5136 10.328 5.4515 0.2699
HCC1937 CTRP2 8.5845 11.9727 4.8338 1.8093
HCC1143 CTRP2 8.8111 11.0433 5.3074 0.4303
BT 231 CTRP2 5.8083 9.232 4.2498 8.011
BT 428 CTRP2 6.3828 9.4231 4.6281 6.1583
BT 422 CTRP2 6.6619 10.2102 4.4511 6.4621
BT 248 CTRP2 6.7138 8.797 5.1781 2.5341
BT 333 CTRP2 6.8779 9.0206 5.1804 2.6604
BT 172 CTRP2 6.9497 11.978 3.7941 9.0269
BT 286 CTRP2 7.0706 10.0657 4.8112 4.0493
BT 504 CTRP2 7.0762 10.1501 4.7747 4.2083
BT 416 CTRP2 7.1945 8.9829 5.3867 1.3648
BT 482 CTRP2 7.278 8.4995 5.6296 0.4416
BT147 CTRP2 7.2808 9.0462 5.4055 1.2026
BT 444 CTRP2 7.2868 8.627 5.5831 0.5755
BT 232 CTRP2 7.2907 11.1383 4.4463 5.3782
BT 320 CTRP2 7.3139 8.3981 5.6839 0.2793
BT 131 CTRP2 7.393 11.3912 4.3942 5.4532
BT 245 CTRP2 7.4656 14.2781 3.0436 11.4657
BT 228 CTRP2 7.5749 9.3446 5.4281 0.7476
BT 239 CTRP2 7.6124 8.7731 5.6648 0.1764
BT 359 CTRP2 7.6793 11.2787 4.6318 3.955
BT 139 CTRP2 7.6841 8.8244 5.6738 0.1437
BT 179 CTRP2 7.7025 8.9781 5.6255 0.2162
BT 330 CTRP2 7.7041 9.275 5.5146 0.515
BT 216 CTRP2 7.7326 9.7156 5.3519 0.9952
BT 145 CTRP2 7.7491 11.1343 4.7407 2.9325
BT 498 CTRP2 7.791 9.2139 5.5741 0.3251
BT 224 CTRP2 7.8376 9.009 5.6657 0.1209
BT 440 CTRP2 7.9023 9.0842 5.6631 0.1289
BT 159 CTRP2 7.9282 9.159 5.6465 0.1271
BT 340 CTRP2 7.9496 9.1757 5.6485 0.139
BT164 CTRP2 7.9948 9.1614 5.6697 0.0887
BT 112 CTRP2 8.0425 9.37 5.6146 0.1448
BT 328 CTRP2 8.292 9.4796 5.6656 0.0645
BT 187 CTRP2 8.444 10.2668 5.4467 0.2981
BT 271 CTRP2 9.3835 23.8838 -0.2688 19.8603
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 8.1063 9.1788 5.7025 0.0472
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-251MG CTRP2 6.5161 9.0941 4.8926 4.0034
SW1783 CTRP2 6.9552 12.5924 3.495 9.0471
SF539 CTRP2 6.9786 10.1799 4.6939 4.1068
SF268 CTRP2 7.0686 10.2205 4.7359 3.8088
GB-1 CTRP2 7.1154 9.0918 5.2936 1.5908
SF126 CTRP2 7.1875 10.299 4.7777 3.4797
LN-18 CTRP2 7.223 8.5867 5.5694 0.5769
KNS-60 CTRP2 7.2909 8.4298 5.6622 0.2985
SNU-466 CTRP2 7.3016 8.3869 5.683 0.2486
Daoy CTRP2 7.306 10.2045 4.8982 2.8579
KNS-81 CTRP2 7.4103 8.6286 5.6369 0.3019
KG-1-C CTRP2 7.4888 8.7405 5.6274 0.2894
SW1088 CTRP2 7.5767 9.7054 5.2781 1.2069
SNU-738 CTRP2 7.5889 9.1652 5.5066 0.5252
SNU-201 CTRP2 7.6184 8.8834 5.6269 0.2414
SNU-626 CTRP2 7.7023 8.9907 5.6208 0.2246
SNU-1105 CTRP2 7.71 8.8702 5.6672 0.147
YKG-1 CTRP2 7.7139 8.9404 5.6436 0.1823
TM-31 CTRP2 7.7788 9.0993 5.6113 0.2174
D283 Med CTRP2 7.7932 10.8826 4.8805 2.3727
SNU-489 CTRP2 7.8005 9.0545 5.6358 0.1713
SF295 CTRP2 7.821 11.6323 4.5556 3.5448
GaMG CTRP2 7.8417 9.5417 5.4711 0.4817
DK-MG CTRP2 7.8633 9.2817 5.5779 0.2496
GMS-10 CTRP2 7.871 9.0971 5.6472 0.1382
U-118MG CTRP2 7.9417 9.4965 5.5301 0.3122
42-MG-BA CTRP2 7.9671 9.7594 5.4412 0.4917
CCF-STTG1 CTRP2 8.0289 9.1045 5.7009 0.0561
CAS-1 CTRP2 8.083 9.4084 5.6161 0.1346
KNS-42 CTRP2 8.0859 9.6996 5.5129 0.2946
Hs 683 CTRP2 8.1443 17.0523 2.1772 12.2288
DBTRG-05MG CTRP2 8.1507 9.7516 5.5194 0.2623
NMC-G1 CTRP2 8.1828 9.6903 5.5538 0.1981
YH-13 CTRP2 8.2104 9.6257 5.5869 0.1461
M059K CTRP2 8.2431 9.637 5.5948 0.13
U-87MG ATCC CTRP2 8.2825 9.5354 5.6436 0.0743
GOS-3 CTRP2 8.2875 9.8816 5.5252 0.2147
KALS-1 CTRP2 8.3349 10.6102 5.2714 0.7169
Becker CTRP2 8.3488 9.8123 5.5723 0.1374
8-MG-BA CTRP2 8.361 9.8574 5.5611 0.1487
LN-229 CTRP2 8.3961 10.1195 5.4814 0.2543
A-172 CTRP2 8.4468 10.1057 5.5056 0.2045
ONS-76 CTRP2 8.4486 9.917 5.5721 0.1203
SNB-75 CTRP2 8.5976 11.1885 5.1613 0.8532
T98G CTRP2 8.7264 10.032 5.6293 0.0431
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-1 CTRP2 6.3042 9.0235 4.7654 4.895
HEC-1-A CTRP2 6.5698 10.4519 4.2618 6.5364
EFE-184 CTRP2 6.7941 8.7266 5.2648 2.081
HEC-151 CTRP2 7.159 8.8619 5.4203 1.0996
KLE CTRP2 7.2882 10.6536 4.6757 3.7485
HEC-265 CTRP2 7.3115 8.3297 5.7083 0.1943
MFE-296 CTRP2 7.3282 10.934 4.569 4.1169
HEC-6 CTRP2 7.763 9.1389 5.5906 0.2599
HEC-108 CTRP2 7.9077 8.904 5.7264 0.0492
HEC-251 CTRP2 8.0329 9.3058 5.6336 0.1227
RL95-2 CTRP2 8.1531 9.4432 5.6294 0.1063
JHUEM-2 CTRP2 8.184 13.1837 4.0613 4.9895
HEC-59 CTRP2 8.2402 9.6688 5.5827 0.1454
MFE-319 CTRP2 8.2449 9.7654 5.5505 0.1879
JHUEM-7 CTRP2 8.3409 9.8141 5.5688 0.1431
HEC-50B CTRP2 8.3791 10.4731 5.3436 0.5256
EN CTRP2 8.4694 12.6793 4.4635 3.1702
ESS-1 CTRP2 8.4892 9.7539 5.6413 0.0545
HEC-1-B CTRP2 8.7685 10.4223 5.5127 0.1326
JHUEM-3 CTRP2 9.0835 11.1178 5.3854 0.2273
AN3-CA CTRP2 9.8435 17.003 3.3139 5.8215
Ishikawa (Heraklio) 02 ER- CTRP2 7.4179 8.3197 5.7528 0.0946
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.3101 3.6647 -2.7116 0.7147
UO-31 CTRP2 6.6721 12.4264 3.3602 10.0834
VMRC-RCZ CTRP2 6.9012 8.771 5.3117 1.7656
TUHR4TKB CTRP2 6.9135 8.8447 5.2853 1.8519
TUHR10TKB CTRP2 7.1791 12.185 3.8607 7.1942
KMRC-2 CTRP2 7.2636 9.6055 5.1481 1.9637
VMRC-RCW CTRP2 7.3184 10.6222 4.7102 3.5728
RCC10RGB CTRP2 7.6843 9.7492 5.3143 1.0078
BFTC-909 CTRP2 8.054 9.2971 5.6442 0.1066
SNU-1272 CTRP2 8.1754 11.1196 4.9855 1.6562
KMRC-1 CTRP2 8.1866 9.6664 5.5637 0.1827
769-P CTRP2 8.2404 9.8511 5.5182 0.2383
CAL-54 CTRP2 8.4143 10.1003 5.4953 0.2278
OS-RC-2 CTRP2 8.4332 9.7476 5.6242 0.0728
786-O CTRP2 8.5401 10.2511 5.489 0.2063
KMRC-3 CTRP2 8.5526 10.4956 5.4059 0.3357
Caki-2 CTRP2 8.7009 9.9387 5.6514 0.0335
Caki-1 CTRP2 8.9808 11.621 5.1604 0.6666
KMRC-20 CTRP2 10.4367 19.2707 2.6342 7.533
ACHN CTRP2 11.3357 21.5865 2.1148 8.2708
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C2BBe1 CTRP2 5.5083 11.6938 2.7614 14.7609
SW948 CTRP2 5.6346 13.9612 1.7395 18.3717
SNU-C5 CTRP2 6.0625 8.8777 4.6428 5.8566
COLO 320 CTRP2 6.2529 9.7738 4.3505 6.727
T84 CTRP2 6.5292 9.4178 4.7427 4.6037
DLD-1 CTRP2 6.8137 8.4827 5.3912 1.5678
NCI-H747 CTRP2 7.1156 21.5015 -0.8106 23.2228
SW1417 CTRP2 7.3249 9.6507 5.1636 1.8407
HT115 CTRP2 7.3683 11.4877 4.3314 5.0085
CW-2 CTRP2 7.455 11.7678 4.2558 5.1887
KM12 CTRP2 7.5186 9.2622 5.4348 0.7665
CL-11 CTRP2 7.5336 11.7187 4.3317 4.7788
NCI-H508 CTRP2 7.5526 9.4029 5.3932 0.8654
HCT 15 CTRP2 7.5541 9.2726 5.4475 0.706
SNU-C1 CTRP2 7.625 13.9941 3.2974 8.7668
HCC-56 CTRP2 7.7031 8.9188 5.6472 0.1795
LS411N CTRP2 7.7046 8.7345 5.7127 0.0892
RCM-1 [Human ESC] CTRP2 7.7079 9.187 5.5499 0.3638
SW620 CTRP2 7.7099 10.8448 4.8491 2.5753
SNU-407 CTRP2 7.7138 11.3284 4.6301 3.3896
RKO CTRP2 7.7282 11.6991 4.4668 3.9973
COLO201 CTRP2 7.732 9.8746 5.2857 1.0598
HCT 8 CTRP2 7.7856 9.0663 5.6259 0.191
COLO 678 CTRP2 7.8009 12.214 4.2718 4.6612
HT-55 CTRP2 7.8077 9.1374 5.6087 0.2131
LS1034 CTRP2 7.8793 9.7616 5.4017 0.6336
HT-29 CTRP2 7.9386 9.0039 5.7035 0.0643
LS123 CTRP2 7.9599 9.6557 5.4778 0.4127
HCT 116 CTRP2 7.9811 9.5116 5.5403 0.2792
SK-CO-1 CTRP2 7.9908 15.8152 2.6708 10.6337
COLO205 CTRP2 8.0014 9.4586 5.5676 0.2252
SNU-1033 CTRP2 8.0091 13.8139 3.6498 6.8166
SNU-C4 CTRP2 8.0442 8.9775 5.7481 0.0254
LS513 CTRP2 8.0604 9.5546 5.5557 0.2279
SNU-61 CTRP2 8.0742 10.0034 5.3933 0.5527
OUMS-23 CTRP2 8.1019 21.4342 -0.0103 19.388
GP2d CTRP2 8.1619 9.7398 5.528 0.2444
SW48 CTRP2 8.2469 9.8566 5.5187 0.2357
CCK-81 CTRP2 8.3248 10.1327 5.4487 0.3327
MDST8 CTRP2 8.349 9.4062 5.7089 0.0265
SNU-503 CTRP2 8.3889 10.1507 5.4674 0.2795
NCI-H716 CTRP2 8.4513 10.582 5.3325 0.5186
LS180 CTRP2 8.6272 10.1484 5.5563 0.1093
LoVo CTRP2 8.7494 10.6398 5.4297 0.2419
SNU-C2A CTRP2 8.8356 12.5919 4.7 2.0325
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 5.6683 7.8953 4.7894 6.049
PLC/PRF/5 CTRP2 6.2121 9.0178 4.695 5.3562
JHH-5 CTRP2 6.3455 8.8319 4.8929 4.2891
SNU-182 CTRP2 6.9431 9.6025 4.9471 3.139
JHH-6 CTRP2 7.1579 8.052 5.7494 0.1702
SNU-878 CTRP2 7.1906 9.5652 5.1228 2.1405
JHH-1 CTRP2 7.5732 8.9942 5.5664 0.3872
Hep 3B2.1-7 CTRP2 7.6403 9.0355 5.579 0.3295
SNU-475 CTRP2 7.7746 9.0291 5.635 0.1794
SK-HEP-1 CTRP2 7.805 8.9504 5.6743 0.1166
SNU-398 CTRP2 7.8783 10.1607 5.2391 1.0931
HLF CTRP2 7.9838 9.6153 5.503 0.4048
Hep-G2 CTRP2 8.129 9.5056 5.599 0.1471
HuH-1 CTRP2 8.1353 9.225 5.697 0.0484
SNU-761 CTRP2 8.1419 19.6166 0.9171 16.5358
JHH-4 CTRP2 8.1735 10.391 5.2854 0.7697
SNU-886 CTRP2 8.3388 9.8939 5.5401 0.1808
JHH-2 CTRP2 8.4053 9.8306 5.5863 0.112
SNU-387 CTRP2 8.691 10.4163 5.4867 0.1768
SNU-423 CTRP2 8.7185 10.0769 5.6118 0.0541
SNU-449 CTRP2 8.7742 10.5891 5.4568 0.1983
Li-7 CTRP2 9.4377 11.527 5.372 0.1762
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 140 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1F CTRP2 0.4229 7.7071 -4.9675 16.1173
NCI-H1581 CTRP2 4.9241 7.0724 4.4428 9.2621
NCI-H211 CTRP2 5.1798 8.2529 4.157 9.7762
DMS 53 CTRP2 5.2235 8.3746 4.1403 9.7426
NCI-H1385 CTRP2 5.3425 7.0662 4.8739 6.4668
NCI-H146 CTRP2 5.4694 7.5489 4.772 6.5725
NCI-H1105 CTRP2 5.7844 7.5954 5.0428 4.7401
NCI-H2106 CTRP2 5.8949 8.0627 4.9081 5.0731
NCI-H1694 CTRP2 5.9212 7.0616 5.4298 2.8316
COLO 668 CTRP2 5.9408 7.6724 5.1425 3.9958
NCI-H810 CTRP2 5.9474 8.0689 4.9502 4.7902
DV-90 CTRP2 5.95 8.9913 4.4916 6.7112
NCI-H1155 CTRP2 6.1665 8.4649 4.9343 4.4356
DMS 454 CTRP2 6.3022 8.7493 4.9003 4.334
COR-L51 CTRP2 6.4525 8.5837 5.0968 3.2615
NCI-H522 CTRP2 6.5581 10.7435 4.108 7.1967
NCI-H1944 CTRP2 6.5949 10.1665 4.4222 5.8262
SK-MES-1 CTRP2 6.6723 8.6609 5.2152 2.4437
NCI-H520 CTRP2 6.6955 9.237 4.9528 3.4739
NCI-H446 CTRP2 6.7196 9.1183 5.0272 3.1347
NCI-H2087 CTRP2 6.7796 9.7006 4.7869 4.0243
Calu-3 CTRP2 6.8328 10.0775 4.6412 4.5392
SBC-5 CTRP2 6.8473 8.6766 5.322 1.7915
NCI-H526 CTRP2 6.9713 8.5256 5.4645 1.1255
NCI-H2170 CTRP2 7.0208 8.8683 5.3393 1.5259
NCI-H2029 CTRP2 7.0635 10.0049 4.8355 3.4181
Sq-1 CTRP2 7.0692 10.996 4.362 5.3203
KNS-62 CTRP2 7.088 9.3428 5.1625 2.1106
Lu-99 CTRP2 7.1141 8.7744 5.4341 1.094
HCC15 CTRP2 7.1208 12.5237 3.6522 8.1352
NCI-H2171 CTRP2 7.1534 9.2509 5.244 1.7314
NCI-H1666 CTRP2 7.1573 11.444 4.2064 5.8205
HARA [Human squamous cell lung carcinoma] CTRP2 7.1996 9.563 5.1292 2.106
RERF-LC-A1 CTRP2 7.2123 10.1019 4.8868 3.0193
HCC2935 CTRP2 7.2269 9.2558 5.2842 1.5083
LK2 CTRP2 7.2427 8.3513 5.6717 0.2989
BEN CTRP2 7.243 8.2291 5.718 0.2001
NCI-H322 CTRP2 7.253 9.1485 5.3462 1.2657
MOR/CPR CTRP2 7.2751 8.3546 5.6842 0.257
HCC44 CTRP2 7.2877 12.0489 4.0046 6.4431
NCI-H1355 CTRP2 7.3037 10.3058 4.8495 3.0486
NCI-H647 CTRP2 7.3152 9.3802 5.2786 1.4405
HCC1438 CTRP2 7.3356 10.2221 4.9085 2.7821
EBC-1 CTRP2 7.3955 9.938 5.075 2.088
NCI-H226 CTRP2 7.4314 8.5094 5.69 0.1879
RERF-LC-Ad1 CTRP2 7.4399 8.5559 5.6763 0.2103
NCI-H1650 CTRP2 7.4647 11.1592 4.5517 4.0035
ChaGo-K-1 CTRP2 7.5162 11.7259 4.3168 4.8616
NCI-H1793 CTRP2 7.5438 9.6171 5.2986 1.1678
NCI-H2286 CTRP2 7.5849 9.9293 5.1858 1.5064
LCLC-97TM1 CTRP2 7.5926 10.0557 5.1347 1.6744
HOP-92 CTRP2 7.6563 10.9025 4.791 2.8503
NCI-H196 CTRP2 7.6701 9.0526 5.5849 0.3051
A-549 CTRP2 7.6835 9.7866 5.2983 1.0577
NCI-H650 CTRP2 7.7077 9.2439 5.5281 0.4127
NCI-H2126 CTRP2 7.7128 8.9347 5.6453 0.18
NCI-H2081 CTRP2 7.736 9.752 5.3386 0.8979
HOP-62 CTRP2 7.747 10.7249 4.9246 2.2619
HCC1195 CTRP2 7.7713 11.7687 4.4615 3.9643
NCI-H1573 CTRP2 7.796 10.7697 4.9325 2.1842
NCI-H460 CTRP2 7.8315 9.2445 5.579 0.2582
COR-L88 CTRP2 7.8372 9.3875 5.5281 0.3565
NCI-H841 CTRP2 7.8373 13.2755 3.7918 6.4973
NCI-H358 CTRP2 7.8983 9.8451 5.3772 0.6868
NCI-H2196 CTRP2 7.9066 9.2505 5.6061 0.1895
NCI-H1092 CTRP2 7.9228 9.7116 5.4406 0.5146
NCI-H838 CTRP2 7.9339 9.2898 5.6024 0.188
SHP-77 CTRP2 7.9485 9.2137 5.6348 0.138
LOU-NH91 CTRP2 7.9687 11.2961 4.7959 2.4955
DMS 114 CTRP2 7.99 10.9339 4.9674 1.8773
LCLC-103H CTRP2 7.9944 8.9464 5.7417 0.0319
EKVX CTRP2 8.0045 11.2024 4.8576 2.2416
LC-1/sq-SF CTRP2 8.0139 9.421 5.5859 0.1926
HCC827 CTRP2 8.054 9.8113 5.4583 0.4152
NCI-H1341 CTRP2 8.0583 9.3817 5.6163 0.1393
NCI-H2228 CTRP2 8.0614 10.245 5.2923 0.8172
Calu-6 CTRP2 8.0651 9.7839 5.4732 0.3795
NCI-H2172 CTRP2 8.0709 9.7732 5.4796 0.3643
IA-LM CTRP2 8.0911 9.6282 5.541 0.2435
NCI-H441 CTRP2 8.1011 10.1811 5.3358 0.6803
NCI-H1435 CTRP2 8.109 14.9955 3.1507 8.6187
DMS 273 CTRP2 8.1114 10.2817 5.3006 0.7655
NCI-H1792 CTRP2 8.114 9.6939 5.5261 0.2621
T3M-10 CTRP2 8.1185 11.9914 4.5699 3.1549
NCI-H661 CTRP2 8.1215 10.1124 5.3717 0.581
NCI-H1339 CTRP2 8.1248 9.3892 5.6378 0.1018
NCI-H1395 CTRP2 8.1267 14.7311 3.2899 8.0544
HCC1588 CTRP2 8.14 9.3005 5.6733 0.0659
HCC1171 CTRP2 8.1498 10.1846 5.356 0.6045
NCI-H727 CTRP2 8.1742 10.0058 5.4348 0.4155
NCI-H1184 CTRP2 8.1835 10.3098 5.322 0.6708
NCI-H1563 CTRP2 8.1852 9.6167 5.5807 0.1594
COR-L95 CTRP2 8.2102 9.8411 5.5101 0.2603
HCC4006 CTRP2 8.2132 9.8063 5.5238 0.2367
NCI-H2405 CTRP2 8.2273 10.1974 5.3844 0.5018
PC-14 CTRP2 8.2303 10.5865 5.2335 0.8746
NCI-H1838 CTRP2 8.2468 10.008 5.4635 0.3316
VMRC-LCD CTRP2 8.2479 10.0471 5.4495 0.358
SW1271 CTRP2 8.253 10.5801 5.2465 0.8264
NCI-H2085 CTRP2 8.2585 9.8951 5.5093 0.2476
NCI-H292 CTRP2 8.2599 9.7918 5.5468 0.1896
NCI-H1734 CTRP2 8.2728 10.2482 5.3843 0.4823
HCC78 CTRP2 8.2799 9.774 5.5605 0.1661
NCI-H1755 CTRP2 8.2967 9.79 5.5611 0.1618
HCC2279 CTRP2 8.3375 10.344 5.3751 0.4749
SK-LU-1 CTRP2 8.3609 10.3019 5.4006 0.4126
RERF-LC-MS CTRP2 8.3938 10.2429 5.4356 0.3337
NCI-H1915 CTRP2 8.4103 9.9142 5.5593 0.1416
HCC95 CTRP2 8.4427 9.8413 5.5959 0.0969
NCI-H2110 CTRP2 8.4548 10.8866 5.2163 0.7912
HCC366 CTRP2 8.4568 10.0797 5.5185 0.1842
EPLC-272H CTRP2 8.4702 11.1896 5.1023 1.0865
NCI-H2122 CTRP2 8.473 9.8055 5.6185 0.073
NCI-H1299 CTRP2 8.4878 10.5376 5.3644 0.4371
HCC2108 CTRP2 8.5279 10.648 5.3395 0.4722
Calu-1 CTRP2 8.5345 12.8912 4.406 3.309
CAL-12T CTRP2 8.5481 10.0534 5.5607 0.1166
Lu-65 CTRP2 8.5496 10.1295 5.535 0.1448
LUDLU-1 CTRP2 8.5602 22.128 -0.0092 18.6424
LXF 289 CTRP2 8.5709 10.5921 5.3777 0.381
NCI-H23 CTRP2 8.5784 10.7222 5.3324 0.467
NCI-H1693 CTRP2 8.5796 10.59 5.382 0.3702
NCI-H1623 CTRP2 8.6003 10.5269 5.4132 0.3083
NCI-H2291 CTRP2 8.6271 10.103 5.5717 0.0947
NCI-H2009 CTRP2 8.6405 10.2383 5.5302 0.1345
HCC1833 CTRP2 8.6409 10.664 5.3791 0.3552
COLO 699 CTRP2 8.6426 10.8994 5.2923 0.5247
RERF-LC-Ad2 CTRP2 8.644 9.9358 5.6333 0.0468
COR-L105 CTRP2 8.6481 10.7818 5.3386 0.4285
NCI-H2030 CTRP2 8.6787 10.3163 5.517 0.1428
NCI-H2342 CTRP2 8.6881 11.5912 5.0422 1.1162
NCI-H1869 CTRP2 8.746 11.8112 4.9803 1.2519
NCI-H1568 CTRP2 8.7528 10.2651 5.5606 0.0888
NCI-H1703 CTRP2 8.7584 10.8128 5.371 0.3327
NCI-H1373 CTRP2 8.7715 10.4328 5.5101 0.1348
NCI-H2023 CTRP2 8.8112 10.49 5.5046 0.1344
NCI-H69 CTRP2 8.9426 17.8247 2.3594 10.3888
SW1573 CTRP2 9.1712 18.1652 2.35 10.1066
COR-L47 CTRP2 9.369 12.0876 5.1454 0.5429
Hs 888.Lu CTRP2 8.5755 10.4015 5.4488 0.2572
⏷ Show the Full List of 140 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.0808 10.9852 4.3754 6.0602
A2780 CTRP2 5.3824 7.6582 4.6361 7.3344
COV434 CTRP2 5.5805 8.8198 4.2534 8.4737
SNU-119 CTRP2 6.2462 13.6479 2.4095 14.6498
TYK-nu CTRP2 6.5632 9.1023 4.9233 3.8007
OVK18 CTRP2 6.6024 8.8992 5.0511 3.2136
OAW42 CTRP2 7.4332 8.6599 5.6347 0.297
OC 314 CTRP2 7.4817 10.7161 4.7701 3.1348
COV362 CTRP2 7.5003 9.7547 5.216 1.4811
EFO-27 CTRP2 7.5181 9.3048 5.4169 0.8194
TOV-21G CTRP2 7.5779 9.0549 5.545 0.5031
DOV13 CTRP2 7.6646 10.3136 5.0609 1.8618
OVCAR-4 CTRP2 7.6887 11.8376 4.3767 4.3972
OVISE CTRP2 7.6929 8.8373 5.6725 0.1435
OV56 CTRP2 7.6984 8.8771 5.6604 0.1601
SNU-840 CTRP2 7.8118 11.1585 4.7669 2.766
RMG-I CTRP2 7.8929 9.8854 5.3586 0.7397
MCAS CTRP2 7.9565 9.7279 5.4488 0.4793
SNU-8 CTRP2 7.9577 9.1974 5.6439 0.1245
COV644 CTRP2 7.967 9.5633 5.5155 0.3317
ES2 CTRP2 7.9974 9.6009 5.5138 0.3237
Caov-3 CTRP2 8.0141 11.1854 4.8705 2.1875
OV7 CTRP2 8.0501 9.3227 5.6339 0.1191
JHOS-2 CTRP2 8.1126 9.4651 5.6071 0.14
SK-OV-3 CTRP2 8.1518 10.1733 5.3613 0.5909
OVSAHO CTRP2 8.1615 9.5191 5.6062 0.1316
OV-90 CTRP2 8.1965 9.7713 5.53 0.2314
ONCO-DG-1 CTRP2 8.2 9.527 5.6173 0.1118
TOV-112D CTRP2 8.2076 10.8783 5.1035 1.2622
JHOC-5 CTRP2 8.2742 9.3968 5.687 0.043
FU-OV-1 CTRP2 8.3275 9.8411 5.5545 0.1639
HEY A8 CTRP2 8.3506 9.6091 5.6423 0.0675
EFO-21 CTRP2 8.397 9.8834 5.5651 0.1371
OVCAR-5 CTRP2 8.5817 10.3008 5.4869 0.1997
JHOM-1 CTRP2 8.6899 9.9899 5.6309 0.0448
OVTOKO CTRP2 8.6955 10.7427 5.3719 0.3506
Kuramochi CTRP2 8.7011 10.472 5.4709 0.1952
OVCAR-8 CTRP2 8.7277 10.4522 5.4876 0.1685
OAW28 CTRP2 8.7743 10.6571 5.4329 0.2313
IGROV-1 CTRP2 9.0342 11.0073 5.406 0.2105
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.1786 8.0461 5.7597 0.1447
SYO-1 CTRP2 7.3845 12.4029 3.9009 7.7407
P-STS CTRP2 7.7236 9.3988 5.4749 0.5324
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.5732 9.4367 5.3894 0.9962
Yamato-SS CTRP2 7.7145 8.7808 5.7003 0.1177
TE 441.T CTRP2 4.8599 7.1706 4.3343 9.8585
A-204 CTRP2 6.0974 9.3051 4.458 6.5661
TE 617.T CTRP2 6.2586 8.1966 5.1412 3.4025
TTC-709 CTRP2 6.2795 8.5732 4.9701 4.7156
Rh41 CTRP2 6.5908 8.9073 5.0388 3.2818
KYM-1 CTRP2 6.7266 9.4862 4.8536 3.832
HT-1080 CTRP2 6.7517 8.2158 5.4762 1.3188
MES-SA CTRP2 6.7662 7.9165 5.6194 0.7837
SW982 CTRP2 7.2884 8.782 5.5208 0.7784
BT-12 CTRP2 7.4482 8.2238 5.7964 0.0505
GCT CTRP2 7.5028 10.5753 4.8482 2.8124
G-402 CTRP2 7.8527 11.6651 4.5599 3.4914
BT-16 CTRP2 7.9819 9.2372 5.6388 0.1456
Rh18 CTRP2 8.0793 15.8349 2.7239 10.2978
RKN CTRP2 8.1039 9.2448 5.6796 0.0649
SK-UT-1 CTRP2 8.1386 9.7964 5.4983 0.3039
Tm87-16 CTRP2 8.2016 9.849 5.5039 0.3161
Hs 729.T CTRP2 8.4091 10.3749 5.393 0.4096
SK-LMS-1 CTRP2 8.5341 10.8847 5.2519 0.6636
G-401 CTRP2 8.9198 10.7964 5.4378 0.193
RD CTRP2 9.3973 11.3585 5.4153 0.1374
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.073 9.7664 5.4829 0.3566
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 CTRP2 7.0893 9.7177 4.9884 2.7807
ACC-MESO-1 CTRP2 7.6463 9.0772 5.5658 0.3557
NCI-H2052 CTRP2 8.0711 10.4584 5.2103 1.0421
MPP 89 CTRP2 8.2757 9.9013 5.5136 0.2358
IST-Mes1 CTRP2 8.3554 10.5278 5.3124 0.6073
MSTO-211H CTRP2 8.3884 10.5422 5.3211 0.5719
JL-1 CTRP2 8.6141 10.1491 5.5514 0.1161
NCI-H28 CTRP2 8.7019 10.3347 5.519 0.1366
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 5.027 9.4304 3.4434 13.0567
PaCa-3 CTRP2 6.5185 7.5732 5.6297 1.0124
DU145 CTRP2 7.3053 9.8156 5.0772 2.1799
VCaP CTRP2 7.3505 11.9303 4.106 5.9396
22Rv1 CTRP2 8.27 10.6361 5.2319 0.8552
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 7.167 10.7558 4.5459 4.4328
YD-15 CTRP2 7.7811 8.6911 5.7542 0.0413
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 5.0335 5.9997 4.9531 7.0146
OCUM-1 CTRP2 5.666 25.7325 -4.1168 32.2796
SNU-16 CTRP2 5.8439 7.6207 5.0835 4.4437
NUGC-3 CTRP2 6.2392 7.6638 5.3908 2.3937
HGC-27 CTRP2 6.2587 8.7606 4.8605 4.5779
GSU CTRP2 6.8175 7.6913 5.7413 0.3544
SNU-620 CTRP2 7.1842 8.4622 5.6016 0.5109
MKN45 CTRP2 7.2538 8.1762 5.7418 0.1526
SNU-1 CTRP2 7.3518 10.5412 4.7698 3.2972
MKN1 CTRP2 7.3719 9.6429 5.194 1.6825
SNU-601 CTRP2 7.3837 11.111 4.5215 4.2301
SNU-5 CTRP2 7.4161 10.5834 4.7907 3.1356
23132/87 CTRP2 7.4861 10.5954 4.8286 2.9061
Hs 746.T CTRP2 7.6822 10.4795 4.9972 2.0689
SNU-216 CTRP2 7.6962 11.1456 4.7036 3.132
GSS CTRP2 7.7037 9.2716 5.5157 0.4435
ECC12 CTRP2 7.8321 8.8281 5.7258 0.0579
NCI-N87 CTRP2 7.9201 17.41 1.8389 13.7987
AGS CTRP2 8.0287 9.2844 5.6394 0.1164
MKN7 CTRP2 8.0789 9.9379 5.4206 0.4873
SH-10-TC CTRP2 8.1636 9.302 5.6809 0.0573
SNU-668 CTRP2 8.1799 9.2912 5.6901 0.0491
KATO III CTRP2 8.2046 10.3054 5.333 0.6326
IM95 CTRP2 8.2257 10.145 5.4037 0.4604
MKN74 CTRP2 8.3053 10.3147 5.3727 0.4937
NUGC-4 CTRP2 8.3276 9.9316 5.5226 0.2086
KE-39 CTRP2 8.3794 12.0607 4.6871 2.474
Fu97 CTRP2 8.5589 15.8117 3.0639 8.3167
LMSU CTRP2 8.6912 14.4251 3.8007 5.3598
SNU-719 CTRP2 8.7723 11.871 4.9685 1.2682
HuG1-N CTRP2 8.9838 17.518 2.5337 9.7012
SNG-M CTRP2 7.39 10.1178 4.9898 2.4101
SNU-685 CTRP2 8.3214 9.5475 5.6529 0.0623
SNU-1077 CTRP2 8.5864 9.9314 5.6153 0.0636
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 CTRP2 6.702 8.5922 5.268 2.1911
8505C CTRP2 6.7822 9.1046 5.0769 2.8437
SW579 CTRP2 7.0996 8.6951 5.4608 1.0166
B-CPAP CTRP2 7.7836 9.2784 5.547 0.3386
FTC-238 CTRP2 7.8675 9.3121 5.5685 0.2654
BHT-101 CTRP2 7.9756 9.6027 5.5043 0.3507
TT2609-C02 CTRP2 8.109 10.286 5.2978 0.7743
TT CTRP2 8.2094 10.0719 5.4245 0.4229
8305C CTRP2 8.2306 9.6605 5.5821 0.1481
FTC-133 CTRP2 8.2517 9.6219 5.6032 0.1188
CGTH-W-1 CTRP2 8.2845 9.6247 5.6139 0.102
ML-1 [Human leukemia] CTRP2 8.659 10.4332 5.469 0.2071
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP2 6.0798 8.2062 4.9929 4.352
HSC-4 CTRP2 6.3029 7.9994 5.273 2.7763
PE/CA-PJ49 CTRP2 6.8495 8.1423 5.5661 0.8887
PE/CA-PJ15 CTRP2 7.2864 8.8966 5.4721 0.8231
SNU-899 CTRP2 7.3429 9.4675 5.2555 1.4945
CAL-27 CTRP2 7.4288 8.8007 5.5785 0.4301
FaDu CTRP2 7.4937 11.7348 4.2976 4.9687
SCC-25 CTRP2 7.5377 9.3608 5.4034 0.8458
BHY CTRP2 7.5896 9.4806 5.3792 0.881
CAL-33 CTRP2 7.6152 9.7512 5.2785 1.1739
BICR 6 CTRP2 7.6501 8.8015 5.6691 0.1593
BICR 22 CTRP2 7.7081 8.9142 5.6508 0.1724
SNU-1076 CTRP2 7.9006 11.4901 4.6688 3.0299
HSC-3 CTRP2 7.9146 9.1265 5.6528 0.1218
YD-8 CTRP2 7.9803 14.2716 3.411 7.7921
YD-10B CTRP2 7.9896 9.3779 5.5921 0.1894
BICR 56 CTRP2 8.0235 9.3948 5.5988 0.1709
SCC-4 CTRP2 8.0448 9.534 5.5571 0.2301
BICR 18 CTRP2 8.1326 9.6295 5.5565 0.2069
SNU-1214 CTRP2 8.1658 10.3359 5.3038 0.7264
BICR 31 CTRP2 8.3125 10.7235 5.2165 0.8713
PE/CA-PJ34 (clone C12) CTRP2 8.3246 9.7865 5.5725 0.1417
SNU-1041 CTRP2 8.4285 10.0474 5.5193 0.1894
SCC-9 CTRP2 8.4629 12.8138 4.3995 3.4067
BICR 16 CTRP2 8.464 10.806 5.2519 0.6981
PE/CA-PJ41 (clone D2) CTRP2 8.4717 9.8172 5.6142 0.0767
Detroit 562 CTRP2 8.6921 10.0946 5.5969 0.0666
SNU-1066 CTRP2 8.7307 10.2345 5.5633 0.0891
SNU-46 CTRP2 8.795 10.5872 5.4651 0.1833
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 6.0042 11.02 3.5231 10.6543
UM-UC-1 CTRP2 6.0806 7.657 5.268 3.1942
253J-BV CTRP2 6.4278 8.4242 5.157 3.0522
U-BLC1 CTRP2 6.9281 8.5572 5.4257 1.3098
639V CTRP2 7.0295 8.1595 5.6514 0.4706
CAL-29 CTRP2 7.1836 8.8457 5.4405 1.0097
SW1710 CTRP2 7.1899 9.88 4.9765 2.6996
BC-3C CTRP2 7.1981 9.1255 5.3259 1.3896
BFTC-905 CTRP2 7.4697 8.907 5.555 0.4672
TCCSUP CTRP2 7.5787 11.309 4.5545 3.8458
HT-1376 CTRP2 7.6361 10.2474 5.0743 1.8424
KU-19-19 CTRP2 7.6472 9.1799 5.5267 0.4451
JMSU-1 CTRP2 7.7012 9.075 5.5893 0.2844
RT-112 CTRP2 7.9286 9.8451 5.3909 0.6342
253J CTRP2 8.0279 9.2473 5.652 0.1023
UM-UC-3 CTRP2 8.4139 15.311 3.2059 7.9757
647V CTRP2 8.4173 9.4639 5.7126 0.0217
VM-CUB-1 CTRP2 8.4217 10.9487 5.1767 0.913
RT-4 CTRP2 8.4397 10.2954 5.4346 0.3207
SCaBER CTRP2 8.4899 9.7549 5.6412 0.0545
5637 CTRP2 8.7329 10.6592 5.4165 0.2659
J82 CTRP2 8.7824 10.3064 5.557 0.0883
KMBC-2 CTRP2 9.1876 16.2767 3.2502 6.8067
T24 CTRP2 10.8326 19.8584 2.6021 7.2058
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.4622 8.4543 5.7218 0.1274

References

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