Details of the Drug

General Information of Drug (ID: DM1Z74X)

Drug Name
Tacedinaline
Synonyms
Acetyldinaline; Tacedinalina; Goe 5549; PD 123654; Ci-994; Goe-5549; PD-123654; Tacedinalina [INN-Spanish]; Tacedinaline [USAN:INN]; C.I. 994; Tacedinaline (USAN/INN); 4-(Acetylamino)-N-(2-aminophenyl)benzamide; 4-acetamido-N-(2-aminophenyl)benzamide; 4-acetamido-n-(2-aminophenyl)benzamid; 4-acetylamino-N-(2'-aminophenyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 269.3
Logarithm of the Partition Coefficient (xlogp) 1.3
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C15H15N3O2
IUPAC Name
4-acetamido-N-(2-aminophenyl)benzamide
Canonical SMILES
CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N
InChI
InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)
InChIKey
VAZAPHZUAVEOMC-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
2746
ChEBI ID
CHEBI:90195
CAS Number
112522-64-2
UNII
UMF554N5FG
DrugBank ID
DB12291
TTD ID
D0W9NH
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Centrosomal protein of 68 kDa (CEP68) OTZDM4J1 CEP68_HUMAN Gene/Protein Processing [3]
Ceramide glucosyltransferase OTRT5P5I CEGT_HUMAN Gene/Protein Processing [3]
Enhancer of filamentation 1 (NEDD9) OTGCFN4M CASL_HUMAN Gene/Protein Processing [3]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Gene/Protein Processing [3]
G-protein coupled receptor 183 (GPR183) OTRILX7G GP183_HUMAN Gene/Protein Processing [3]
Glycine dehydrogenase (GLDC) OTVVDNW0 GCSP_HUMAN Gene/Protein Processing [3]
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) OTJQL0I3 HEY1_HUMAN Gene/Protein Processing [3]
Interferon alpha-inducible protein 6 (IFI6) OTWOOAM4 IFI6_HUMAN Gene/Protein Processing [3]
Interleukin-3 receptor subunit alpha (IL3RA) OTDC3Y8O IL3RA_HUMAN Gene/Protein Processing [3]
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) OTGM06VJ IDI1_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histone deacetylase 1 (HDAC1) DTT HDAC1 6.27E-01 0.11 0.33
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 107 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.2696 4.3559 1.0903 25.7613
MEC1 CTRP2 3.5663 6.2498 2.9951 11.9702
JM1 CTRP2 1.2961 3.4337 1.2557 25.1078
EoL-1 CTRP2 -0.1798 1.6379 -0.1828 34.8144
SEM CTRP2 -0.0636 1.2486 -0.0639 34.0313
MHH-CALL-4 CTRP2 0.7766 4.3297 0.5607 29.1619
KMS-20 CTRP2 1.0291 3.5772 0.9586 26.9883
Kasumi-1 CTRP2 1.0722 2.0255 1.0721 26.4638
Mino CTRP2 1.113 3.6147 1.0432 26.4272
GA-10 CTRP2 1.2494 3.1464 1.2284 25.3532
TALL-1 [Human adult T-ALL] CTRP2 1.3022 4.5564 1.0826 25.6849
697 CTRP2 1.3134 2.692 1.3102 24.867
SET-2 CTRP2 1.314 2.1664 1.314 24.8526
M-07e CTRP2 1.3184 2.1322 1.3183 24.8235
OPM-2 CTRP2 1.3439 2.1806 1.3439 24.6532
MOLP-8 CTRP2 1.3619 2.3276 1.3617 24.5341
OCI-AML-3 CTRP2 1.3839 3.2014 1.3643 24.4523
ST486 CTRP2 1.3952 2.5954 1.3938 24.316
A3/Kawakami CTRP2 1.4149 2.0232 1.4149 24.1799
RCH-ACV CTRP2 1.4155 3.8921 1.3288 24.4703
Kasumi-2 CTRP2 1.4841 2.4201 1.4839 23.7202
NU-DHL-1 CTRP2 1.488 3.4695 1.4537 23.8082
A4/Fukuda CTRP2 1.4904 2.7243 1.4884 23.6839
MOLM-16 CTRP2 1.5181 3.0079 1.5107 23.5175
KMS-34 CTRP2 1.5193 2.5512 1.5188 23.4863
HuT 78 CTRP2 1.5494 2.8152 1.5467 23.2931
NU-DUL-1 CTRP2 1.5778 2.9198 1.5736 23.1091
SU-DHL-8 CTRP2 1.5891 3.1238 1.5792 23.0528
CMK CTRP2 1.671 2.1057 1.671 22.4739
CA46 CTRP2 1.6759 4.5696 1.4861 23.0951
Daudi CTRP2 1.7143 4.6407 1.5118 22.8843
MOTN-1 CTRP2 1.7185 3.2563 1.7065 22.1976
HPB-ALL CTRP2 1.7642 3.4015 1.7462 21.9134
HH [Human lymphoma] CTRP2 1.7781 3.3779 1.7619 21.815
SUP-B15 CTRP2 1.8252 3.5724 1.7979 21.5386
SK-MM-2 CTRP2 1.8662 4.3358 1.7405 21.6039
KMS-12-BM CTRP2 1.8704 3.2036 1.8639 21.1673
OCI-AML-5 CTRP2 1.8887 2.9399 1.8874 21.0279
F-36P CTRP2 1.9033 4.1987 1.8048 21.2623
MM1.S CTRP2 1.9129 3.1558 1.9084 20.8775
BV-173 CTRP2 1.9273 3.8606 1.8778 20.9336
Mono-Mac-1 CTRP2 1.9777 4.5575 1.8169 20.9842
SU-DHL-6 CTRP2 2.0129 4.9099 1.7717 21.0354
MOLM-6 CTRP2 2.0658 4.5387 1.9166 20.3573
KMS-28BM CTRP2 2.1466 5.295 1.8101 20.4898
HEL 92.1.7 CTRP2 2.1758 4.1383 2.1066 19.3459
MOLT-16 CTRP2 2.2296 3.6348 2.2141 18.8043
SUP-M2 CTRP2 2.2396 4.2571 2.1569 18.9679
RPMI-8226 CTRP2 2.3069 3.827 2.281 18.3247
U266B1 CTRP2 2.3287 4.3684 2.2341 18.4155
SUP-T1 CTRP2 2.3786 4.0175 2.3379 17.8974
BL-70 CTRP2 2.3911 4.8093 2.2095 18.3065
SKM-1 CTRP2 2.3927 3.3603 2.3905 17.6733
Namalwa CTRP2 2.448 5.0887 2.1986 18.171
JJN-3 CTRP2 2.466 4.5925 2.3398 17.6117
EJM CTRP2 2.5039 4.909 2.3076 17.6082
EB1 CTRP2 2.5205 6.5771 1.76 19.5929
OCI-M1 CTRP2 2.6274 4.3808 2.5537 16.3538
THP-1 CTRP2 2.6618 4.9055 2.4807 16.5031
MOLT-3 CTRP2 2.6956 4.3972 2.6244 15.8906
JeKo-1 CTRP2 2.7057 5.1408 2.4651 16.4255
Ri-1 CTRP2 2.7677 5.8411 2.3043 16.8376
LP-1 CTRP2 2.7843 4.6112 2.6813 15.4109
RS4;11 CTRP2 2.798 5.8042 2.3501 16.5785
AMO1 CTRP2 2.8085 5.26 2.5422 15.8357
KMS-11 CTRP2 2.8139 4.6184 2.7118 15.2107
PL21 CTRP2 2.8317 4.4287 2.7655 14.9667
HL-60 CTRP2 2.8317 4.5315 2.7478 15.0282
OCI-Ly3 CTRP2 2.8906 5.3932 2.5902 15.415
L-540 CTRP2 2.9135 4.7124 2.8004 14.5862
SR CTRP2 2.9587 5.2463 2.71 14.773
L-363 CTRP2 2.9857 4.3732 2.939 13.8738
MOLP-2 CTRP2 3.1102 5.2044 2.8878 13.6699
ME1 CTRP2 3.1108 5.9255 2.6418 14.5863
SIG-M5 CTRP2 3.1563 5.4124 2.8728 13.5883
KYO-1 CTRP2 3.1626 4.2484 3.1412 12.6088
AML-193 CTRP2 3.1672 4.7508 3.0678 12.8489
MHH-CALL-3 CTRP2 3.1724 9.7684 0.9853 20.8056
KMS-18 CTRP2 3.1865 4.7617 3.0864 12.7228
KO52 CTRP2 3.1967 4.9667 3.0487 12.8252
OCI-Ly19 CTRP2 3.2075 5.429 2.9229 13.2524
Karpas-422 CTRP2 3.2481 6.2339 2.6673 14.1064
SUP-HD1 CTRP2 3.2865 6.5617 2.572 14.3727
OCI-Ly10 CTRP2 3.3296 7.0491 2.4054 14.9137
MC116 CTRP2 3.3503 4.7767 3.2612 11.593
TF-1 CTRP2 3.3725 5.4071 3.1093 12.0771
RPMI-6666 CTRP2 3.4436 5.5256 3.1458 11.7344
SU-DHL-10 CTRP2 3.4768 5.0635 3.3284 10.9633
K-562 CTRP2 3.6107 6.4442 2.9587 11.995
Pfeiffer CTRP2 3.6337 6.7007 2.8702 12.2845
RL CTRP2 3.6682 6.1893 3.1269 11.1821
L-428 CTRP2 3.6888 5.5807 3.3904 10.1108
DB CTRP2 3.7415 5.7036 3.4005 9.9237
SU-DHL-4 CTRP2 3.7447 5.3625 3.528 9.4336
P3HR-1 CTRP2 3.8506 5.8615 3.4538 9.4172
SUP-T11 CTRP2 4.0988 5.8384 3.7238 7.6956
U-937 CTRP2 4.1275 6.3855 3.5124 8.4594
MJ CTRP2 4.1896 10.6284 1.5116 16.4311
DND-41 CTRP2 4.4139 5.7129 4.1042 5.3655
HD-MY-Z CTRP2 4.575 7.4679 3.4222 7.7823
Granta-519 CTRP2 4.8267 7.906 3.4284 7.2247
Ci-1 CTRP2 4.9879 5.6654 4.6856 1.6209
Hs 611.T CTRP2 5.1691 10.152 2.5938 10.0435
Toledo CTRP2 5.5646 13.2592 1.3621 14.2278
BL-41 CTRP2 6.2229 11.1087 2.9295 6.8464
REC-1 CTRP2 7.197 9.3037 4.3303 0.6431
Karpas-620 CTRP2 7.2044 9.1353 4.3984 0.481
⏷ Show the Full List of 107 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.3438 9.016 0.5223 24.6077
TE15 CTRP2 4.4076 6.6207 3.6783 7.1022
TE-1 CTRP2 3.3008 5.5342 2.9884 12.7361
TE-6 CTRP2 3.7393 10.474 1.1777 18.7285
OE33 CTRP2 3.9665 7.7826 2.6986 12.1552
KYSE-70 CTRP2 4.1797 6.4456 3.5371 8.2293
OE19 CTRP2 4.4197 7.3986 3.3133 8.5791
OE21 CTRP2 4.6751 8.4067 3.0464 9.1373
EC-GI-10 CTRP2 4.8011 10.0799 2.3211 11.8912
KYSE-410 CTRP2 4.8091 7.0231 3.8527 5.4827
TE-14 CTRP2 4.861 6.1988 4.308 3.4686
KYSE-510 CTRP2 5.2334 6.9783 4.23 3.0752
TE-11 CTRP2 5.4213 9.6242 3.0605 7.6354
TE-4 CTRP2 5.4643 13.1443 1.3389 14.5039
TE-5 CTRP2 5.5494 8.9437 3.498 5.5879
KYSE-450 CTRP2 5.5968 7.1629 4.4026 1.7993
KYSE-30 CTRP2 5.6688 7.9884 4.0547 3.0982
KYSE-150 CTRP2 5.7415 8.2752 3.9666 3.3484
KYSE-520 CTRP2 6.547 13.0714 2.2038 9.2576
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.6667 9.9259 3.1009 7.0399
HuP-T4 CTRP2 4.3222 8.1137 2.873 10.621
SU.86.86 CTRP2 4.4401 19.9481 -2.9168 28.9064
Panc 05.04 CTRP2 4.4664 6.2474 3.9126 6.0044
MIA PaCa-2 CTRP2 4.5169 5.6775 4.2253 4.6179
TCC-Pan2 CTRP2 4.5342 5.7676 4.2024 4.6652
Capan-1 CTRP2 4.8109 7.3587 3.6873 6.1715
Panc 04.03 CTRP2 4.8488 6.6049 4.0957 4.3819
Panc 08.13 CTRP2 4.8728 7.1872 3.8268 5.4591
L3.3 CTRP2 4.9456 7.6716 3.6475 6.0651
PK-59 CTRP2 4.9738 8.9848 3.0151 8.6638
DAN-G CTRP2 5.0811 6.4384 4.3778 2.732
PaTu 8988s CTRP2 5.1489 8.2908 3.5075 6.261
PaTu 8902 CTRP2 5.1713 8.6629 3.3398 6.9231
AsPC-1 CTRP2 5.1745 8.3403 3.5035 6.2299
HPAC CTRP2 5.2625 7.6716 3.9078 4.3727
PSN1 CTRP2 5.3196 11.5428 2.0216 12.0993
Hs 766T CTRP2 5.3813 7.0708 4.2964 2.5505
SNU-410 CTRP2 5.7235 8.6446 3.7741 4.1626
SW1990 CTRP2 5.7326 8.4208 3.8897 3.6756
Panc 10.05 CTRP2 5.8373 8.9673 3.698 4.3
Panc 03.27 CTRP2 5.9519 8.2058 4.1409 2.3619
YAPC CTRP2 6.0532 8.1123 4.2474 1.8308
HuP-T3 CTRP2 6.0973 12.4779 2.1645 10.1421
PK-45H CTRP2 6.1618 12.2102 2.3447 9.3124
Panc 02.03 CTRP2 6.3083 10.0017 3.5234 4.3252
KP-2 CTRP2 6.3611 10.9507 3.1035 5.9344
PaTu 8988t CTRP2 6.8599 7.958 4.6914 0.0869
Capan-2 CTRP2 6.8684 9.6067 4.0441 1.7283
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.4786 17.6313 -0.891 21.9316
Hs 852.T CTRP2 2.7904 5.4537 2.4617 16.185
LOX-IMVI CTRP2 2.9155 6.9368 2.027 17.4874
IGR-1 CTRP2 3.0838 5.4572 2.7793 14.1474
G-361 CTRP2 3.6342 5.2676 3.4391 10.0871
WM88 CTRP2 3.6804 7.4022 2.5986 13.2532
UACC-257 CTRP2 3.7018 7.4261 2.6087 13.1593
SK-MEL-5 CTRP2 3.7646 4.8844 3.6879 8.791
Hs 936.T CTRP2 3.9335 5.1006 3.8162 7.813
MeWo CTRP2 4.0251 7.2467 3.0103 10.744
IGR-37 CTRP2 4.2071 6.7653 3.4151 8.6569
SK-MEL-30 CTRP2 4.2622 8.248 2.7517 11.2565
WM266-4 CTRP2 4.2915 5.0221 4.2287 5.235
IPC-298 CTRP2 4.2963 7.914 2.9468 10.3739
Hs 294T CTRP2 4.3266 5.5691 4.0744 5.7151
COLO 800 CTRP2 4.3597 8.1477 2.8908 10.4637
Hs 944.T CTRP2 4.3779 6.1348 3.8778 6.3624
A-375 CTRP2 4.4041 6.4447 3.7586 6.7824
K029AX CTRP2 4.4709 6.224 3.928 5.9311
UACC-62 CTRP2 4.5322 8.1792 3.0321 9.5001
SK-MEL-31 CTRP2 4.5747 6.1519 4.0631 5.1307
HT-144 CTRP2 4.5755 6.2747 4.0051 5.3665
A101D CTRP2 4.6381 5.187 4.5553 3.0053
WM115 CTRP2 4.6506 5.4449 4.4646 3.3218
A2058 CTRP2 4.6598 5.4557 4.4694 3.2789
SK-MEL-3 CTRP2 4.7285 7.7281 3.431 7.4167
SK-MEL-2 CTRP2 4.776 5.2323 4.6851 2.1236
RVH-421 CTRP2 4.8065 5.5671 4.5655 2.5248
SK-MEL-24 CTRP2 4.9647 6.6981 4.1502 3.9154
MDA-MB-435S CTRP2 5.0109 6.275 4.401 2.7699
WM793 CTRP2 5.0395 6.5889 4.2681 3.2726
WM983B CTRP2 5.0499 7.9703 3.586 6.1194
SK-MEL-28 CTRP2 5.3475 7.4004 4.1085 3.3863
WM1799 CTRP2 5.4344 8.9431 3.4098 6.1535
COLO 792 CTRP2 5.4687 8.5999 3.6067 5.272
COLO 829 CTRP2 5.5138 9.1813 3.3529 6.2528
WT2-iPS CTRP2 5.8594 9.7479 3.3324 5.7659
Hs 940.T CTRP2 5.876 7.4592 4.4395 1.3158
HMCB CTRP2 5.901 10.1576 3.1618 6.4017
Hs 895.T CTRP2 6.3799 12.4647 2.3798 8.8205
Hs 839.T CTRP2 6.3806 7.5256 4.6635 0.2575
CJM [Human melanoma] CTRP2 6.3837 12.2486 2.4883 8.3796
Hs 688(A).T CTRP2 6.3969 7.4762 4.6885 0.2021
Mel JuSo CTRP2 6.6509 13.4143 2.111 9.4609
Hs 934.T CTRP2 6.7843 7.8786 4.6917 0.0994
IGR-39 CTRP2 6.8695 8.4155 4.5309 0.3378
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.0629 14.2602 1.2553 13.73
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 0.8794 3.0607 0.85 27.8464
SK-N-DZ CTRP2 1.8025 3.4351 1.7839 21.6603
Kelly CTRP2 2.1634 4.4381 2.0427 19.6074
CHP-126 CTRP2 2.2842 3.7036 2.2665 18.4482
NH-6 CTRP2 2.7701 5.9692 2.2602 16.9968
KP-N-YN CTRP2 3.1099 8.7358 1.4138 19.3539
SK-N-BE(2) CTRP2 3.1156 5.7057 2.7279 14.2471
NB1 CTRP2 3.3878 4.742 3.3092 11.3069
SK-N-FI CTRP2 3.7878 5.5629 3.5033 9.4024
SK-N-SH CTRP2 4.1591 8.4514 2.5566 12.2917
SK-N-AS CTRP2 4.4784 7.9545 3.0944 9.3576
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 5.5342 9.8234 3.0499 7.4801
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 888.T CTRP2 3.1836 9.1595 1.2862 19.6545
A-673 CTRP2 3.2258 5.6608 2.8628 13.4232
SK-N-MC CTRP2 3.2816 4.9341 3.1496 12.2031
SK-ES-1 CTRP2 4.0029 6.2577 3.4435 9.0529
TC71 CTRP2 4.4433 6.5428 3.7499 6.7244
CAL-78 CTRP2 4.8979 10.4995 2.1938 12.218
SaOS-2 CTRP2 4.9654 6.352 4.3236 3.1856
HOS CTRP2 5.1643 7.6028 3.8636 4.7366
SJSA-1 CTRP2 5.5345 20.6299 -2.3438 25.5625
G-292 clone A141B1 CTRP2 6.0744 11.034 2.8586 7.3683
Hs 822.T CTRP2 6.2453 7.2543 4.7096 0.216
MG-63 CTRP2 6.2809 12.076 2.4983 8.502
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578Bst CTRP2 0.1182 123.7313 -58.4526 48.8559
BT-474 CTRP2 1.2353 6.1491 0.5408 27.7701
DU4475 CTRP2 1.6335 4.3508 1.4858 23.2299
MDA-MB-361 CTRP2 2.7208 4.6374 2.607 15.8714
HCC1143 CTRP2 2.7496 6.3629 2.0878 17.7084
MDA-MB-453 CTRP2 2.8216 4.3172 2.7715 14.9788
HCC2218 CTRP2 2.9227 6.0042 2.4108 15.9941
Hs 578T CTRP2 2.9911 7.786 1.7321 18.4315
HCC1500 CTRP2 3.7865 6.5889 3.0757 11.0733
HCC1428 CTRP2 4.0476 6.5474 3.3583 9.2795
AU565 CTRP2 4.2031 9.5134 2.0751 14.16
MDA-MB-157 CTRP2 4.2472 5.8544 3.8709 6.7239
T-47D CTRP2 4.7484 6.6478 3.9844 5.0618
HCC202 CTRP2 4.8443 11.9764 1.4103 15.4414
CAL-85-1 CTRP2 4.8528 10.7483 2.0312 12.9688
ZR-75-30 CTRP2 4.9094 10.2934 2.3066 11.7335
MDA-MB-231 CTRP2 4.9907 7.8628 3.5902 6.2167
MDA-MB-468 CTRP2 5.014 6.1706 4.4558 2.5335
BT-20 CTRP2 5.1891 7.0646 4.1522 3.4804
ZR-75-1 CTRP2 5.2297 7.7591 3.8382 4.7235
BT-549 CTRP2 5.3652 9.7237 2.9665 8.1286
CAL-51 CTRP2 5.4265 11.2179 2.27 10.8939
HCC38 CTRP2 5.4945 8.2519 3.7986 4.4295
BT 245 CTRP2 2.8718 6.591 2.1255 17.226
BT 428 CTRP2 3.4685 5.594 3.1484 11.6526
BT 239 CTRP2 3.7303 6.0485 3.2507 10.5324
BT 145 CTRP2 3.8021 7.8438 2.5106 13.3117
BT 231 CTRP2 3.9511 8.6832 2.2492 14.0224
BT164 CTRP2 4.3419 8.144 2.8762 10.564
BT 139 CTRP2 5.0474 9.0706 3.0338 8.4423
BT 359 CTRP2 5.1098 9.0737 3.084 8.112
BT 330 CTRP2 5.1248 8.9435 3.1614 7.7593
BT 112 CTRP2 5.1825 8.7717 3.2945 7.092
BT 333 CTRP2 5.3203 7.7037 3.9371 4.1482
BT 216 CTRP2 5.3461 6.7873 4.4099 2.1382
BT 131 CTRP2 5.3493 15.5207 0.0581 19.2703
BT 320 CTRP2 5.3971 7.6223 4.0363 3.6037
BT 232 CTRP2 5.4133 6.7128 4.4941 1.6907
BT 416 CTRP2 5.4693 6.7005 4.538 1.4344
BT 286 CTRP2 5.4962 10.8978 2.4852 9.8861
BT 504 CTRP2 5.5788 8.294 3.8406 4.1172
BT147 CTRP2 5.6362 7.8451 4.1013 2.9571
BT 187 CTRP2 5.6376 14.4689 0.8169 16.111
BT 482 CTRP2 5.7488 8.7294 3.7509 4.2189
BT 172 CTRP2 5.774 8.2345 4.0088 3.1301
BT 159 CTRP2 5.8444 9.1035 3.6368 4.5394
BT 444 CTRP2 5.9237 10.4075 3.0557 6.8021
BT 422 CTRP2 6.4453 12.0586 2.6251 7.7351
BT 224 CTRP2 6.5716 11.6961 2.8892 6.4882
BT 440 CTRP2 6.5719 9.6127 3.8729 2.6403
BT 328 CTRP2 6.6515 10.7975 3.3716 4.4653
BT 498 CTRP2 6.9748 8.2043 4.6477 0.1165
BT 340 CTRP2 7.2749 8.5809 4.6254 0.0918
BT 248 CTRP2 7.2941 14.555 2.0082 8.8993
BT 228 CTRP2 7.3519 8.4837 4.6844 0.0387
BT 179 CTRP2 10.2997 19.8322 1.435 7.265
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 3.1483 5.5755 2.8091 13.8485
KNS-60 CTRP2 3.5084 11.6802 0.3731 22.1628
A-172 CTRP2 4.482 6.5418 3.7875 6.4793
SF268 CTRP2 4.5823 6.8986 3.7087 6.5749
Hs 683 CTRP2 4.5857 6.8691 3.7263 6.4941
U-118MG CTRP2 4.825 8.4711 3.1449 8.4164
KG-1-C CTRP2 5.1251 6.5004 4.3825 2.6303
42-MG-BA CTRP2 5.2387 6.5829 4.4305 2.2291
YH-13 CTRP2 5.2414 9.6397 2.9088 8.5967
Becker CTRP2 5.3226 7.4482 4.0657 3.6071
YKG-1 CTRP2 5.3811 7.9863 3.8437 4.4332
8-MG-BA CTRP2 5.4353 6.6311 4.5484 1.4401
DK-MG CTRP2 5.4448 13.4833 1.1539 15.2384
U-251MG CTRP2 5.5416 8.8498 3.5385 5.4321
GOS-3 CTRP2 5.5872 7.1406 4.4068 1.7954
GaMG CTRP2 5.6487 9.558 3.2692 6.3716
SW1783 CTRP2 5.6776 11.116 2.5188 9.4256
DBTRG-05MG CTRP2 5.7096 7.2435 4.4375 1.5167
CCF-STTG1 CTRP2 5.7505 7.0568 4.5479 1.0543
T98G CTRP2 5.9633 7.7533 4.3575 1.5221
SW1088 CTRP2 6.1239 8.082 4.303 1.5478
SF539 CTRP2 6.1651 10.7726 3.052 6.437
KNS-42 CTRP2 6.216 8.3155 4.2512 1.638
KALS-1 CTRP2 6.2517 12.5358 2.2511 9.541
GMS-10 CTRP2 6.255 11.4461 2.7878 7.3721
SNB-75 CTRP2 6.5701 10.1976 3.6012 3.6759
M059K CTRP2 6.8345 15.3612 1.2912 12.3004
TM-31 CTRP2 8.1918 15.7971 2.01 7.6841
KNS-81 CTRP2 8.996 26.7538 -2.7191 20.8288
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-3 CTRP2 3.723 8.9845 1.888 16.0067
ESS-1 CTRP2 3.8704 7.4859 2.7465 12.1901
HEC-151 CTRP2 4.3424 7.1465 3.3632 8.5493
MFE-319 CTRP2 4.5688 5.9117 4.1706 4.7073
EFE-184 CTRP2 4.7509 8.1011 3.2651 8.0649
JHUEM-7 CTRP2 4.7531 7.7319 3.4508 7.2826
JHUEM-1 CTRP2 4.9142 8.1526 3.3805 7.249
HEC-1-A CTRP2 5.1332 8.1949 3.5426 6.1431
AN3-CA CTRP2 5.6101 10.935 2.5563 9.3903
EN CTRP2 5.6584 10.6149 2.7528 8.4958
MFE-296 CTRP2 5.773 8.932 3.6693 4.5164
HEC-50B CTRP2 12.8993 29.0821 -1.2303 12.362
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 CTRP2 4.7336 7.3845 3.6062 6.6731
TUHR14TKB CTRP2 4.8466 7.656 3.5703 6.5889
786-O CTRP2 4.8971 6.6334 4.124 4.1627
UO-31 CTRP2 4.9992 7.7637 3.6469 5.9618
ACHN CTRP2 5.07 7.371 3.9024 4.751
Caki-1 CTRP2 5.1958 12.1061 1.6389 13.8566
VMRC-RCZ CTRP2 5.3107 9.4131 3.0778 7.7628
TUHR10TKB CTRP2 5.4384 7.5628 4.0966 3.2851
RCC10RGB CTRP2 5.5796 7.3918 4.2813 2.3099
KMRC-3 CTRP2 5.5805 9.4244 3.2836 6.4274
A-498 CTRP2 5.6201 8.2484 3.8932 3.8348
VMRC-RCW CTRP2 5.6271 7.423 4.2987 2.1721
KMRC-2 CTRP2 5.8623 9.275 3.566 4.802
KMRC-1 CTRP2 7.6891 17.4874 0.8654 12.5091
Caki-2 CTRP2 8.7475 18.7669 0.9695 10.663
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW948 CTRP2 1.6416 4.3121 1.502 48.836
SNU-C1 CTRP2 2.0628 4.6383 1.8917 20.4546
GP2d CTRP2 3.14 6.8702 2.2884 15.8713
LoVo CTRP2 3.3504 5.7756 2.9548 12.721
RCM-1 [Human ESC] CTRP2 3.4402 5.5992 3.116 11.8558
CW-2 CTRP2 3.4845 5.4725 3.2085 11.3816
CL-11 CTRP2 3.4924 5.8051 3.0957 11.7847
NCI-H747 CTRP2 3.5437 6.9044 2.688 13.2405
COLO 320 CTRP2 3.6762 8.2953 2.1741 14.9728
MDST8 CTRP2 3.6853 4.633 3.6499 9.1746
HCC-56 CTRP2 3.7825 6.0651 3.2985 10.2054
SNU-503 CTRP2 3.9055 9.7701 1.6762 16.4227
NCI-H716 CTRP2 4.1007 6.3805 3.4876 8.6266
NCI-H508 CTRP2 4.2063 7.1444 3.2343 9.3971
HT-55 CTRP2 4.2317 7.8664 2.9098 10.6729
HCT 8 CTRP2 4.3546 5.8396 3.9878 5.9813
LS123 CTRP2 4.4147 6.2318 3.8692 6.3068
SW1417 CTRP2 4.4393 6.3914 3.8181 6.4551
SNU-C5 CTRP2 4.4528 7.7417 3.1758 9.0754
SNU-1033 CTRP2 4.5401 6.5813 3.8238 6.1947
SNU-407 CTRP2 4.7598 7.055 3.793 5.8363
T84 CTRP2 4.8035 8.4987 3.1126 8.5954
HCT 15 CTRP2 5.015 6.062 4.5109 2.2999
COLO 678 CTRP2 5.1057 7.4282 3.9032 4.6799
C2BBe1 CTRP2 5.1783 8.6529 3.3505 6.8653
LS1034 CTRP2 5.2272 7.5366 3.9472 4.2711
SNU-C4 CTRP2 5.2571 6.1085 4.6775 1.177
SNU-61 CTRP2 5.269 7.5416 3.9777 4.0688
KM12 CTRP2 5.3829 10.0907 2.7975 8.8003
SW620 CTRP2 5.7358 10.2882 2.9741 7.4487
RKO CTRP2 6.1162 11.6289 2.5971 8.3667
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 CTRP2 1.9005 3.5496 1.8781 21.0201
HuH-6 CTRP2 3.0155 5.6392 2.6433 14.8526
Hep-G2 CTRP2 3.6085 8.2685 2.1213 15.348
JHH-2 CTRP2 3.7966 8.9096 1.9939 15.4113
SNU-886 CTRP2 4.193 5.668 3.8933 14.5647
JHH-4 CTRP2 4.2332 6.1028 3.7469 7.2526
HuH-1 CTRP2 4.3416 6.0764 3.8683 6.4914
JHH-5 CTRP2 4.6008 10.1786 2.0989 13.2103
HLF CTRP2 4.7212 5.9339 4.3081 3.781
SNU-398 CTRP2 4.8556 6.7195 4.0447 4.5813
PLC/PRF/5 CTRP2 4.8998 7.7736 3.5575 6.5349
SNU-423 CTRP2 4.9748 8.274 3.3712 7.1679
SNU-761 CTRP2 5.3875 19.5487 -1.9239 24.842
SK-HEP-1 CTRP2 5.647 8.2574 3.9082 3.7309
SNU-449 CTRP2 5.6936 10.3641 2.9043 7.8087
JHH-6 CTRP2 5.9742 6.8327 4.7559 0.2305
SNU-475 CTRP2 6.4698 7.8795 4.5658 0.4401
SNU-387 CTRP2 7.9235 17.2004 1.1662 11.1074
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 94 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1105 CTRP2 1.2038 2.7119 1.1987 25.6037
NCI-H146 CTRP2 1.3256 2.2162 1.3255 24.7752
NCI-H2171 CTRP2 1.5737 4.2998 1.431 23.6106
NCI-H1184 CTRP2 1.6057 5.3141 1.2146 24.2753
NCI-H810 CTRP2 1.609 3.4518 1.5815 22.9793
COR-L88 CTRP2 1.6196 5.2105 1.2602 24.0704
NCI-H1694 CTRP2 1.7341 3.1498 1.7265 22.079
DV-90 CTRP2 1.7833 4.062 1.6975 22.0175
COR-L51 CTRP2 2.53 5.6888 2.1009 18.2854
DMS 273 CTRP2 2.5881 6.0254 2.0439 18.3305
NCI-H1341 CTRP2 2.5919 4.387 2.5145 16.6026
NCI-H889 CTRP2 2.6227 6.0715 2.064 18.1558
NCI-H2081 CTRP2 2.6866 4.919 2.5045 16.3417
DMS 454 CTRP2 2.8978 7.2485 1.8748 18.124
NCI-H2228 CTRP2 3.3538 10.7505 0.6837 21.4514
NCI-H1915 CTRP2 3.4341 6.4066 2.7912 13.1212
PC-14 CTRP2 3.4511 6.7167 2.676 13.5284
NCI-H446 CTRP2 3.4547 5.247 3.2502 11.3144
NCI-H2141 CTRP2 3.4879 5.8739 3.0643 11.9174
NCI-H2126 CTRP2 3.5013 5.3079 3.2817 11.0603
NCI-H1435 CTRP2 3.6058 6.805 2.7955 12.6534
NCI-H520 CTRP2 3.6254 6.7488 2.8405 12.4239
NCI-H2110 CTRP2 3.6783 7.4192 2.5887 13.298
EBC-1 CTRP2 3.6871 5.3323 3.4756 9.7968
VMRC-LCD CTRP2 3.7027 6.3436 3.0972 11.2069
NCI-H2029 CTRP2 3.7156 7.1633 2.7439 12.5811
NCI-H2087 CTRP2 3.7176 6.3457 3.1116 11.1108
NCI-H23 CTRP2 3.9673 7.4673 2.8496 11.5371
NCI-H661 CTRP2 4.0594 6.1762 3.5372 8.5346
COR-L95 CTRP2 4.1848 5.7589 3.847 6.9833
NCI-H1755 CTRP2 4.2652 5.7918 3.9166 6.4963
NCI-H1666 CTRP2 4.2684 7.9484 2.904 10.6133
NCI-H522 CTRP2 4.2853 6.2762 3.7204 7.2277
NCI-H2444 CTRP2 4.3094 25.1238 -5.6142 33.6089
LCLC-97TM1 CTRP2 4.3463 6.5598 3.648 7.3723
COLO 668 CTRP2 4.3499 7.866 3.02 9.9505
COR-L105 CTRP2 4.4706 7.5823 3.2705 8.6428
SK-MES-1 CTRP2 4.4822 7.0292 3.5518 7.4504
NCI-H1092 CTRP2 4.4849 7.1285 3.5059 7.6341
NCI-H1623 CTRP2 4.4962 8.9177 2.6339 11.2322
NCI-H1944 CTRP2 4.5451 8.5007 2.8843 10.088
Sq-1 CTRP2 4.5549 8.4388 2.9238 9.9028
HOP-92 CTRP2 4.5665 7.5587 3.3697 8.0191
LXF 289 CTRP2 4.585 7.4525 3.4389 7.691
NCI-H647 CTRP2 4.5946 9.1269 2.6171 11.0935
EPLC-272H CTRP2 4.6719 7.7976 3.3462 7.8907
RERF-LC-MS CTRP2 4.6743 7.9904 3.2526 8.277
NCI-H1651 CTRP2 4.6778 8.1739 3.1645 8.6379
NCI-H1339 CTRP2 4.6942 7.4936 3.517 7.1298
NCI-H841 CTRP2 4.751 5.8725 4.3662 3.4726
HCC1195 CTRP2 4.7719 5.9317 4.3573 3.4612
LK2 CTRP2 4.7782 5.564 4.5394 2.6994
NCI-H1693 CTRP2 4.7813 5.938 4.363 3.4158
SW1271 CTRP2 4.7839 12.1133 1.2906 16.0232
NCI-H2170 CTRP2 4.8128 8.463 3.1384 8.4684
NCI-H1568 CTRP2 4.8961 16.1305 -0.6227 22.296
Lu-65 CTRP2 4.8972 7.5078 3.688 5.9921
NCI-H838 CTRP2 4.9091 8.439 3.2331 7.878
NCI-H1869 CTRP2 4.9231 9.4068 2.7613 9.8241
LUDLU-1 CTRP2 4.9346 6.417 4.2646 3.4958
NCI-H1355 CTRP2 4.9865 9.9828 2.5267 10.6738
DMS 114 CTRP2 5.0034 7.3431 3.8607 5.0553
HCC4006 CTRP2 5.0928 8.0313 3.591 6.0162
HCC1438 CTRP2 5.0964 7.3077 3.9558 4.4763
NCI-H1703 CTRP2 5.1051 6.4044 4.4143 2.5335
NCI-H2196 CTRP2 5.2802 7.0683 4.2217 3.029
NCI-H1793 CTRP2 5.475 6.8624 4.4644 1.7215
NCI-H322 CTRP2 5.5033 9.1245 3.373 6.187
KNS-62 CTRP2 5.5058 7.539 4.1576 2.9256
A-549 CTRP2 5.5596 7.4414 4.2434 2.4931
NCI-H1650 CTRP2 5.5747 7.8723 4.0444 3.2838
NCI-H2023 CTRP2 5.7108 8.238 3.9631 3.4087
NCI-H1373 CTRP2 5.8013 9.0509 3.6316 4.6272
NCI-H2342 CTRP2 5.8876 8.3346 4.0379 2.8532
T3M-10 CTRP2 5.9722 9.029 3.7623 3.8397
LOU-NH91 CTRP2 5.9811 8.5334 4.0052 2.8563
NCI-H1395 CTRP2 5.9832 13.5303 1.5562 12.7283
HOP-62 CTRP2 6.0319 8.8213 3.9019 3.1973
NCI-H2122 CTRP2 6.0471 14.032 1.3565 13.3775
SW1573 CTRP2 6.1151 8.7773 3.977 2.7919
NCI-H1563 CTRP2 6.1251 8.0952 4.2977 1.5654
NCI-H2085 CTRP2 6.3657 11.3664 2.9054 6.7268
HCC2935 CTRP2 6.3887 20.65 -1.6683 22.3787
SK-LU-1 CTRP2 6.4591 10.3349 3.4648 4.3529
EKVX CTRP2 6.5287 10.6303 3.3705 4.6319
LC-1/sq-SF CTRP2 6.5438 13.185 2.146 9.4909
Calu-6 CTRP2 6.7782 13.7478 2.0393 9.5445
Calu-1 CTRP2 6.8227 11.5934 3.1069 5.277
ChaGo-K-1 CTRP2 6.8717 14.3428 1.816 10.2636
NCI-H1792 CTRP2 7.0414 11.2529 3.4044 3.857
RERF-LC-Ad2 CTRP2 7.0782 13.2369 2.494 7.3291
NCI-H460 CTRP2 7.5648 15.7468 1.6201 9.9717
NCI-H226 CTRP2 8.3812 31.6155 -5.5731 27.1446
Hs 888.Lu CTRP2 5.0733 11.8668 1.6572 14.0235
⏷ Show the Full List of 94 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 2.9036 6.6569 2.1319 17.1148
SYO-1 CTRP2 3.0555 5.1927 2.8317 14.0386
H-STS CTRP2 4.1024 5.1808 3.9761 6.7232
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.0038 6.2344 3.4547 9.0062
Aska-SS CTRP2 4.3795 5.3338 4.2233 4.9966
KYM-1 CTRP2 2.9678 4.8123 2.8371 14.287
TE 441.T CTRP2 3.0311 6.3959 2.3728 15.8374
G-401 CTRP2 3.6652 8.1287 2.2427 14.7236
TE 617.T CTRP2 3.8193 6.9131 2.9623 11.4437
HT-1080 CTRP2 4.0226 7.7211 2.7819 11.6825
A-204 CTRP2 4.0918 7.8261 2.7972 11.4578
Rh18 CTRP2 4.2005 5.7161 3.8813 6.8071
Tm87-16 CTRP2 4.3627 7.5889 3.1673 9.3119
RD CTRP2 4.4941 9.2875 2.4485 12.0032
TTC-709 CTRP2 4.6267 7.8506 3.2796 8.265
SW982 CTRP2 4.7764 6.1474 4.2563 3.869
MES-SA CTRP2 4.8894 5.5832 4.637 2.0372
GCT CTRP2 5.0652 6.8717 4.1481 3.7276
G-402 CTRP2 5.3708 9.9287 2.8686 8.5261
SK-LMS-1 CTRP2 5.525 10.8427 2.5354 9.6276
RKN CTRP2 5.7138 7.8933 4.1319 2.72
BT-16 CTRP2 5.8571 8.7776 3.8041 3.838
Hs 729.T CTRP2 6.3475 12.4578 2.3596 8.9526
SK-UT-1 CTRP2 6.3915 11.105 3.05 6.1053
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.8726 7.1705 3.835 5.4254
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.314 9.1265 4.4467 0.3401
A2780 CTRP2 2.7584 4.8651 2.5962 15.7926
OAW28 CTRP2 3.7874 6.7962 2.9835 11.4395
RMG-I CTRP2 3.7986 7.1625 2.8269 12.0402
OVCAR-5 CTRP2 3.8859 10.0595 1.5163 17.0938
IGROV-1 CTRP2 4.1799 7.4912 3.0426 10.2454
COV644 CTRP2 4.2794 7.4279 3.1675 9.5012
OVK18 CTRP2 4.488 6.593 3.7686 6.5426
JHOM-1 CTRP2 4.5424 8.8747 2.6964 10.875
MCAS CTRP2 4.5738 7.0916 3.6063 7.019
EFO-27 CTRP2 4.5793 9.0579 2.638 11.039
TOV-112D CTRP2 4.6812 7.9024 3.3025 8.054
OC 314 CTRP2 4.9185 6.2017 4.3578 3.1385
Caov-3 CTRP2 4.9284 7.7939 3.5718 6.4173
HEY A8 CTRP2 5.0038 7.5526 3.7563 5.4931
OV-90 CTRP2 5.0419 9.2659 2.9316 8.8803
FU-OV-1 CTRP2 5.3066 7.5974 3.9793 3.9959
EFO-21 CTRP2 5.3362 8.4698 3.5684 5.6634
TOV-21G CTRP2 5.3401 7.0921 4.2554 2.7876
OAW42 CTRP2 5.5609 8.2816 3.8335 4.1755
TYK-nu CTRP2 5.8529 9.4439 3.4767 5.1828
OVCAR-4 CTRP2 5.8968 12.4969 2.0025 11.1309
SK-OV-3 CTRP2 5.9561 8.5239 3.9932 2.9375
OVCAR-8 CTRP2 6.0881 12.8719 1.9628 10.96
JHOS-2 CTRP2 6.1715 11.1827 2.8564 7.2236
OV56 CTRP2 6.3038 10.103 3.472 4.5364
COV362 CTRP2 6.562 11.7876 2.8385 6.7051
SNU-840 CTRP2 7.2536 12.8736 2.7823 5.9739
OV7 CTRP2 8.8714 23.7155 -1.3259 17.5436
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 CTRP2 4.5199 7.0667 3.5687 7.2954
MSTO-211H CTRP2 4.9556 11.0139 1.9853 12.9489
MPP 89 CTRP2 5.1537 7.4757 3.9186 4.5252
NCI-H2452 CTRP2 5.3421 10.2287 2.696 9.2963
NCI-H2052 CTRP2 5.3793 7.206 4.2284 2.835
JL-1 CTRP2 5.5256 6.7959 4.5299 1.391
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 1.8406 4.9802 1.5654 22.3024
LNCaP clone FGC CTRP2 3.2675 6.1073 2.7384 13.7792
DU145 CTRP2 4.8375 9.1509 2.8163 9.7658
PaCa-3 CTRP2 5.7559 10.0976 3.0835 6.9621
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 5.3014 9.7312 2.9116 8.474
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 1.1975 4.1152 1.0585 26.1017
SNU-16 CTRP2 2.4833 5.1588 2.2173 17.9963
Fu97 CTRP2 2.9236 6.59 2.1804 16.8731
NCC-StC-K140 CTRP2 3.3934 6.3092 2.7895 13.2373
NUGC-3 CTRP2 3.7302 5.0163 3.6177 9.1482
IM95 CTRP2 3.9859 6.027 3.5264 8.7699
SNU-1 CTRP2 4.2558 7.9341 2.8992 10.6618
MKN74 CTRP2 4.4399 6.7928 3.6265 7.2391
Hs 746.T CTRP2 4.4421 9.0273 2.5312 11.7731
KATO III CTRP2 4.561 6.1952 4.0292 5.302
HGC-27 CTRP2 4.6957 8.124 3.2052 8.4303
SNU-216 CTRP2 4.832 9.5635 2.6055 10.6542
KE-39 CTRP2 4.8733 7.321 3.7605 5.7362
SNU-601 CTRP2 5.0097 6.2289 4.423 2.6795
MKN7 CTRP2 5.0526 7.86 3.6435 5.8727
SH-10-TC CTRP2 5.7241 9.0753 3.5635 5.0288
HuG1-N CTRP2 5.7773 8.595 3.8366 3.8246
LMSU CTRP2 6.7332 13.3034 2.2237 8.892
SNU-685 CTRP2 4.3568 9.2871 2.3259 12.8021
SNG-M CTRP2 4.579 7.4049 3.4569 7.6288
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] CTRP2 -2.0998 28.4122 -13.0212 49.3657
SW579 CTRP2 3.9782 8.3758 2.4239 13.2489
TT2609-C02 CTRP2 4.721 8.2839 3.1478 8.6179
FTC-133 CTRP2 5.0482 7.3311 3.9042 4.7855
FTC-238 CTRP2 7.4036 15.3282 1.7111 9.8652
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PE/CA-PJ49 CTRP2 3.262 5.6443 2.9077 13.1508
SCC-25 CTRP2 3.7344 7.7061 2.5097 13.4789
BICR 56 CTRP2 3.9395 6.8644 3.1048 10.5704
SCC-4 CTRP2 4.3381 6.3553 3.7361 7.0338
BICR 18 CTRP2 4.6549 8.592 2.9364 9.6387
CAL-27 CTRP2 4.7955 6.1953 4.2503 3.8515
BICR 22 CTRP2 4.9136 7.9416 3.4855 6.8094
SCC-9 CTRP2 5.1308 7.6342 3.8207 4.9792
FaDu CTRP2 5.1532 6.7561 4.2774 3.0199
YD-8 CTRP2 5.2241 8.1582 3.6345 5.5883
PE/CA-PJ34 (clone C12) CTRP2 5.2742 7.3085 4.0977 3.5574
BICR 31 CTRP2 5.3245 9.6349 2.9782 8.1541
PE/CA-PJ15 CTRP2 5.3851 9.1018 3.2922 6.7322
HSC-4 CTRP2 5.3979 9.763 2.9728 8.043
CAL-33 CTRP2 5.404 7.9154 3.8965 4.174
HSC-2 CTRP2 5.9388 8.3115 4.0826 2.6074
PE/CA-PJ41 (clone D2) CTRP2 6.4284 15.7661 0.7888 14.7965
BICR 16 CTRP2 6.579 12.4272 2.5405 7.8708
BICR 6 CTRP2 6.6649 15.2468 1.2227 12.8285
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 0.766 8.1951 -5.809 11.8966
U-BLC1 CTRP2 3.7602 5.4238 3.5237 9.4045
647V CTRP2 4.0296 7.8051 2.7482 11.8041
UM-UC-1 CTRP2 4.7513 11.5923 1.5231 15.1942
HT-1376 CTRP2 4.8891 23.3526 -4.2395 30.5005
SCaBER CTRP2 4.9878 7.0517 3.9932 4.529
KMBC-2 CTRP2 5.2229 6.7308 4.3449 2.613
T24 CTRP2 5.5345 9.5248 3.1984 6.861
RT-112 CTRP2 5.6307 10.6073 2.7352 8.6167
BC-3C CTRP2 5.8095 9.9697 3.1866 6.4476
J82 CTRP2 6.2545 10.4546 3.2693 5.4213
UM-UC-3 CTRP2 6.724 8.4046 4.4728 0.5376
RT-4 CTRP2 7.1021 14.2473 2.0245 9.1156
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 4.9815 7.7463 3.6406 6.0231

References

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